메뉴 건너뛰기




Volumn 2016, Issue , 2016, Pages

Nitroxyl (HNO): A reduced form of nitric oxide with distinct chemical, pharmacological, and therapeutic properties

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; HEALTH CARE; MEDICINE;

EID: 84953311113     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2016/4867124     Document Type: Review
Times cited : (12)

References (134)
  • 2
    • 18944394614 scopus 로고    scopus 로고
    • The physiological chemistry and biological activity of nitroxyl (HNO): The neglected, misunderstood, and enigmatic nitrogen oxide
    • J. M. Fukuto, M. D. Bartberger, A. S. Dutton, N. Paolocci, D. A. Wink, and K. N. Houk, The physiological chemistry and biological activity of nitroxyl (HNO): the neglected, misunderstood, and enigmatic nitrogen oxide, Chemical Research in Toxicology, vol. 18, no. 5, pp. 790-801, 2005.
    • (2005) Chemical Research in Toxicology , vol.18 , Issue.5 , pp. 790-801
    • Fukuto, J.M.1    Bartberger, M.D.2    Dutton, A.S.3    Paolocci, N.4    Wink, D.A.5    Houk, K.N.6
  • 3
    • 0028902552 scopus 로고
    • Nitric oxide synthases: Properties and catalytic mechanism
    • O. W. Griffith and D. J. Stuehr, Nitric oxide synthases: properties and catalytic mechanism, Annual Review of Physiology, vol. 57, pp. 707-736, 1995.
    • (1995) Annual Review of Physiology , vol.57 , pp. 707-736
    • Griffith, O.W.1    Stuehr, D.J.2
  • 4
    • 0025784834 scopus 로고
    • Endogenous nitric oxide: Physiology, pathology and clinical relevance
    • S. Moncada and E. A. Higgs, Endogenous nitric oxide: physiology, pathology and clinical relevance, European Journal of Clinical Investigation, vol. 21, no. 4, pp. 361-374, 1991.
    • (1991) European Journal of Clinical Investigation , vol.21 , Issue.4 , pp. 361-374
    • Moncada, S.1    Higgs, E.A.2
  • 5
    • 0000707453 scopus 로고
    • Nitric oxide activates guanylate cyclase and increases guanosine 3′:5′-cyclic monophosphate levels in various tissue preparations
    • W. P. Arnold, C. K. Mittal, S. Katsuki, and F. Murad, Nitric oxide activates guanylate cyclase and increases guanosine 3′:5′-cyclic monophosphate levels in various tissue preparations, Proceedings of the National Academy of Sciences of the United States of America, vol. 74, no. 8, pp. 3203-3207, 1977.
    • (1977) Proceedings of the National Academy of Sciences of the United States of America , vol.74 , Issue.8 , pp. 3203-3207
    • Arnold, W.P.1    Mittal, C.K.2    Katsuki, S.3    Murad, F.4
  • 6
    • 0032382795 scopus 로고    scopus 로고
    • NOproblem for nitroglycerin: Organic nitrate chemistry and therapy
    • G. R. J. Thatcher, NOproblem for nitroglycerin: organic nitrate chemistry and therapy, Chemical Society Reviews, vol. 27, no. 5, pp. 331-337, 1998.
    • (1998) Chemical Society Reviews , vol.27 , Issue.5 , pp. 331-337
    • Thatcher, G.R.J.1
  • 7
    • 0029928061 scopus 로고    scopus 로고
    • CGMPmediates the vascular and platelet actions of nitric oxide: Confirmation using an inhibitor of the soluble guanylyl cyclase
    • M. A. Moro, R. J. R. Russell, S. Cellek et al., cGMPmediates the vascular and platelet actions of nitric oxide: confirmation using an inhibitor of the soluble guanylyl cyclase, Proceedings of the National Academy of Sciences of the United States of America, vol. 93, no. 4, pp. 1480-1485, 1996.
    • (1996) Proceedings of the National Academy of Sciences of the United States of America , vol.93 , Issue.4 , pp. 1480-1485
    • Moro, M.A.1    Russell, R.J.R.2    Cellek, S.3
  • 8
    • 0031923571 scopus 로고    scopus 로고
    • Role of nitric oxide in the biology, physiology and pathophysiology of reproduction
    • M. Rosselli, P. J. Keller, and R. K. Dubey, Role of nitric oxide in the biology, physiology and pathophysiology of reproduction, Human Reproduction Update, vol. 4, no. 1, pp. 3-24, 1998.
    • (1998) Human Reproduction Update , vol.4 , Issue.1 , pp. 3-24
    • Rosselli, M.1    Keller, P.J.2    Dubey, R.K.3
  • 9
    • 33846553066 scopus 로고    scopus 로고
    • The pharmacology of nitroxyl (HNO) and its therapeutic potential: Not just the Janus face of NO1
    • N. Paolocci, M. I. Jackson, B. E. Lopez et al., The pharmacology of nitroxyl (HNO) and its therapeutic potential: not just the Janus face of NO1, Pharmacology andTherapeutics, vol. 113, no. 2, pp. 442-458, 2007.
    • (2007) Pharmacology AndTherapeutics , vol.113 , Issue.2 , pp. 442-458
    • Paolocci, N.1    Jackson, M.I.2    Lopez, B.E.3
  • 10
    • 21044451423 scopus 로고    scopus 로고
    • The chemistry and biology of nitroxyl (HNO): A chemically unique species with novel and important biological activity
    • J. M. Fukuto, A. S. Dutton, and K. N. Houk, The chemistry and biology of nitroxyl (HNO): a chemically unique species with novel and important biological activity, ChemBioChem, vol. 6, no. 4, pp. 612-619, 2005.
    • (2005) ChemBioChem , vol.6 , Issue.4 , pp. 612-619
    • Fukuto, J.M.1    Dutton, A.S.2    Houk, K.N.3
  • 11
    • 0345306150 scopus 로고    scopus 로고
    • Oxidation and nitrosylation of oxyhemoglobin by S-nitrosoglutathione via nitroxyl anion
    • N. Y. Spencer, N. K. Patel, A. Keszler, and N. Hogg, Oxidation and nitrosylation of oxyhemoglobin by S-nitrosoglutathione via nitroxyl anion, Free Radical Biology and Medicine, vol. 35, no. 11, pp. 1515-1526, 2003.
    • (2003) Free Radical Biology and Medicine , vol.35 , Issue.11 , pp. 1515-1526
    • Spencer, N.Y.1    Patel, N.K.2    Keszler, A.3    Hogg, N.4
  • 12
    • 0021994944 scopus 로고
    • Biologic activity of hydroxylamine: A review
    • P. Gross and R. P. Smith, Biologic activity of hydroxylamine: a review, Critical Reviews in Toxicology, vol. 14, no. 1, pp. 87-99, 1985.
    • (1985) Critical Reviews in Toxicology , vol.14 , Issue.1 , pp. 87-99
    • Gross, P.1    Smith, R.P.2
  • 14
    • 0345455370 scopus 로고
    • Sopra la nitroidrossilammina
    • A. Angeli, Sopra la nitroidrossilammina, Gazzetta Chimica Italiana, vol. 26, pp. 17-25, 1896.
    • (1896) Gazzetta Chimica Italiana , vol.26 , pp. 17-25
    • Angeli, A.1
  • 15
    • 0001546977 scopus 로고
    • Nuove ricerche sopra lacido nitroidrossilamminico
    • A. A. A. F. Angelico, Nuove ricerche sopra lacido nitroidrossilamminico, Gazzetta Chimica Italiana, vol. 33, p. 245, 1903.
    • (1903) Gazzetta Chimica Italiana , vol.33 , pp. 245
    • Angelico, A.A.A.F.1
  • 16
    • 1642343324 scopus 로고    scopus 로고
    • Mechanisms of HNO and NO production from Angelis salt: Density functional and CBS-QB3 theory predictions
    • A. S. Dutton, J. M. Fukuto, and K. N. Houk, Mechanisms of HNO and NO production from Angelis salt: density functional and CBS-QB3 theory predictions, Journal of the American Chemical Society, vol. 126, no. 12, pp. 3795-3800, 2004.
    • (2004) Journal of the American Chemical Society , vol.126 , Issue.12 , pp. 3795-3800
    • Dutton, A.S.1    Fukuto, J.M.2    Houk, K.N.3
  • 17
    • 11844279035 scopus 로고    scopus 로고
    • The chemistry of nitroxyl (HNO) and implications in biology
    • K. M. Miranda, The chemistry of nitroxyl (HNO) and implications in biology, Coordination Chemistry Reviews, vol. 249, no. 3-4, pp. 433-455, 2005.
    • (2005) Coordination Chemistry Reviews , vol.249 , Issue.3-4 , pp. 433-455
    • Miranda, K.M.1
  • 18
    • 0344616890 scopus 로고    scopus 로고
    • Orthogonal properties of the redox siblings nitroxyl and nitric oxide in the cardiovascular system: A novel redox paradigm
    • D. A. Wink, K. M. Miranda, T. Katori et al., Orthogonal properties of the redox siblings nitroxyl and nitric oxide in the cardiovascular system: a novel redox paradigm, The American Journal of Physiology-Heart and Circulatory Physiology, vol. 285, no. 6, pp. H2264-H2276, 2003.
    • (2003) The American Journal of Physiology-Heart and Circulatory Physiology , vol.285 , Issue.6 , pp. H2264-H2276
    • Wink, D.A.1    Miranda, K.M.2    Katori, T.3
  • 19
    • 8644291670 scopus 로고    scopus 로고
    • Nitroxyl triggers Ca2+ release from skeletal and cardiac sarcoplasmic reticulum by oxidizing ryanodine receptors
    • E. Cheong, V. Tumbev, J. Abramson, G. Salama, and D. A. Stoyanovsky, Nitroxyl triggers Ca2+ release from skeletal and cardiac sarcoplasmic reticulum by oxidizing ryanodine receptors, Cell Calcium, vol. 37, no. 1, pp. 87-96, 2005.
    • (2005) Cell Calcium , vol.37 , Issue.1 , pp. 87-96
    • Cheong, E.1    Tumbev, V.2    Abramson, J.3    Salama, G.4    Stoyanovsky, D.A.5
  • 20
    • 84906053204 scopus 로고    scopus 로고
    • Nitroxyl (HNO) for treatment of acute heart failure
    • A. Arcaro, G. Lembo, and C. G. Tocchetti, Nitroxyl (HNO) for treatment of acute heart failure, Current Heart Failure Reports, vol. 11, no. 3, pp. 227-235, 2014.
    • (2014) Current Heart Failure Reports , vol.11 , Issue.3 , pp. 227-235
    • Arcaro, A.1    Lembo, G.2    Tocchetti, C.G.3
  • 21
    • 0000336110 scopus 로고
    • Pulse radiolytic study of short-lived by-products of nitric oxide-reduction in aqueous solution
    • M. Graetzel, S. Taniguchi, and A. Henglein, Pulse radiolytic study of short-lived by-products of nitric oxide-reduction in aqueous solution, Berichte der Bunsen-Gesellschaft, vol. 74, no. 10, pp. 1003-1010, 1970.
    • (1970) Berichte der Bunsen-Gesellschaft , vol.74 , Issue.10 , pp. 1003-1010
    • Graetzel, M.1    Taniguchi, S.2    Henglein, A.3
  • 24
    • 0037188503 scopus 로고    scopus 로고
    • Nitroxyl and its anion in aqueous solutions: Spin states, protic equilibria, and reactivities toward oxygen and nitric oxide
    • V. Shafirovich and S. V. Lymar, Nitroxyl and its anion in aqueous solutions: spin states, protic equilibria, and reactivities toward oxygen and nitric oxide, Proceedings of the National Academy of Sciences of the United States of America, vol. 99, no. 11, pp. 7340-7345, 2002.
    • (2002) Proceedings of the National Academy of Sciences of the United States of America , vol.99 , Issue.11 , pp. 7340-7345
    • Shafirovich, V.1    Lymar, S.V.2
  • 26
    • 0032554614 scopus 로고    scopus 로고
    • Reaction between S-nitrosothiols and thiols: Generation of nitroxyl (HNO) and subsequent chemistry
    • P. S. Wong, J. Hyun, J. M. Fukuto et al., Reaction between S-nitrosothiols and thiols: generation of nitroxyl (HNO) and subsequent chemistry, Biochemistry, vol. 37, no. 16, pp. 5362-5371, 1998.
    • (1998) Biochemistry , vol.37 , Issue.16 , pp. 5362-5371
    • Wong, P.S.1    Hyun, J.2    Fukuto, J.M.3
  • 27
    • 33644850093 scopus 로고    scopus 로고
    • Discriminating formation of HNO from other reactive nitrogen oxide species
    • S. Donzelli, M. G. Espey, D. D. Thomas et al., Discriminating formation of HNO from other reactive nitrogen oxide species, Free Radical Biology andMedicine, vol. 40, no. 6, pp. 1056-1066, 2006.
    • (2006) Free Radical Biology AndMedicine , vol.40 , Issue.6 , pp. 1056-1066
    • Donzelli, S.1    Espey, M.G.2    Thomas, D.D.3
  • 29
    • 33847801561 scopus 로고
    • Thermal decomposition of oxyhyponitrite (sodium trioxodinitrate(II)) in aqueous solution
    • F. T. Bonner and B. Ravid, Thermal decomposition of oxyhyponitrite (sodium trioxodinitrate(II)) in aqueous solution, Inorganic Chemistry, vol. 14, no. 3, pp. 558-563, 1975.
    • (1975) Inorganic Chemistry , vol.14 , Issue.3 , pp. 558-563
    • Bonner, F.T.1    Ravid, B.2
  • 31
    • 0032525919 scopus 로고    scopus 로고
    • Mechanisms of inhibition of aldehyde dehydrogenase by nitroxyl, the active metabolite of the alcohol deterrent agent cyanamide
    • E. G. DeMaster, B. Redfern, and H. T. Nagasawa, Mechanisms of inhibition of aldehyde dehydrogenase by nitroxyl, the active metabolite of the alcohol deterrent agent cyanamide, Biochemical Pharmacology, vol. 55, no. 12, pp. 2007-2015, 1998.
    • (1998) Biochemical Pharmacology , vol.55 , Issue.12 , pp. 2007-2015
    • DeMaster, E.G.1    Redfern, B.2    Nagasawa, H.T.3
  • 32
    • 0025200713 scopus 로고
    • Evidence for nitroxyl in the catalase-mediated bioactivation of the alcohol deterrent agent cyanamide
    • H. T. Nagasawa, E. G. DeMaster, B. Redfern, F. N. Shirota, and D. J. W. Goon, Evidence for nitroxyl in the catalase-mediated bioactivation of the alcohol deterrent agent cyanamide, Journal of Medicinal Chemistry, vol. 33, no. 12, pp. 3120-3122, 1990.
    • (1990) Journal of Medicinal Chemistry , vol.33 , Issue.12 , pp. 3120-3122
    • Nagasawa, H.T.1    DeMaster, E.G.2    Redfern, B.3    Shirota, F.N.4    Goon, D.J.W.5
  • 33
    • 0026360175 scopus 로고
    • Complexes of ·nO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects
    • C. M. Maragos, D. Morley, D. A. Wink et al., Complexes of ·NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects, Journal ofMedicinal Chemistry, vol. 34, no. 11, pp. 3242-3247, 1991.
    • (1991) Journal OfMedicinal Chemistry , vol.34 , Issue.11 , pp. 3242-3247
    • Maragos, C.M.1    Morley, D.2    Wink, D.A.3
  • 34
    • 0027409381 scopus 로고
    • Mechanism of vascular relaxation induced by the nitric oxide (NO)/nucleophile complexes, a new class of NO-based vasodilators
    • D. Morley, C. M. Maragos, X. Y. Zhang, M. Boignon, D. A. Wink, and L. K. Keefer, Mechanism of vascular relaxation induced by the nitric oxide (NO)/nucleophile complexes, a new class of NO-based vasodilators, Journal of Cardiovascular Pharmacology, vol. 21, no. 4, pp. 670-676, 1993.
    • (1993) Journal of Cardiovascular Pharmacology , vol.21 , Issue.4 , pp. 670-676
    • Morley, D.1    Maragos, C.M.2    Zhang, X.Y.3    Boignon, M.4    Wink, D.A.5    Keefer, L.K.6
  • 35
    • 0027382013 scopus 로고
    • Complexes of nitric oxide with nucleophiles as agents for the controlled biological release of nitric oxide: Antiplatelet effect
    • J. G. Giodati, A. A. Quyyumi, N. Hussain, and L. K. Keefer, Complexes of nitric oxide with nucleophiles as agents for the controlled biological release of nitric oxide: antiplatelet effect, Thrombosis and Haemostasis, vol. 70, no. 4, pp. 654-658, 1993.
    • (1993) Thrombosis and Haemostasis , vol.70 , Issue.4 , pp. 654-658
    • Giodati, J.G.1    Quyyumi, A.A.2    Hussain, N.3    Keefer, L.K.4
  • 36
    • 23844527684 scopus 로고    scopus 로고
    • Comparison of the NO and HNO donating properties of diazeniumdiolates: Primary amine adducts release HNO in vivo
    • K. M. Miranda, T. Katori, C. L. Torres de Holding et al., Comparison of the NO and HNO donating properties of diazeniumdiolates: primary amine adducts release HNO in vivo, Journal of Medicinal Chemistry, vol. 48, no. 26, pp. 8220-8228, 2005.
    • (2005) Journal of Medicinal Chemistry , vol.48 , Issue.26 , pp. 8220-8228
    • Miranda, K.M.1    Katori, T.2    Torres De Holding, L.C.3
  • 37
    • 33645498579 scopus 로고    scopus 로고
    • Mechanism of pH-dependent decomposition of monoalkylamine diazeniumdiolates to form HNO and NO, deduced from the model compound methylamine diazeniumdiolate, density functional theory, and CBSQB3 calculations
    • A. S. Dutton, C. P. Suhrada, K. M. Miranda, D. A. Wink, J. M. Fukuto, and K. N. Houk, Mechanism of pH-dependent decomposition of monoalkylamine diazeniumdiolates to form HNO and NO, deduced from the model compound methylamine diazeniumdiolate, density functional theory, and CBSQB3 calculations, Inorganic Chemistry, vol. 45, no. 6, pp. 2448-2456, 2006.
    • (2006) Inorganic Chemistry , vol.45 , Issue.6 , pp. 2448-2456
    • Dutton, A.S.1    Suhrada, C.P.2    Miranda, K.M.3    Wink, D.A.4    Fukuto, J.M.5    Houk, K.N.6
  • 38
    • 0026321495 scopus 로고
    • DNA deaminating ability and genotoxicity of nitric oxide and its progenitors
    • D. A. Wink, K. S. Kasprzak, C. M. Maragos et al., DNA deaminating ability and genotoxicity of nitric oxide and its progenitors, Science, vol. 254, no. 5034, pp. 1001-1003, 1991.
    • (1991) Science , vol.254 , Issue.5034 , pp. 1001-1003
    • Wink, D.A.1    Kasprzak, K.S.2    Maragos, C.M.3
  • 39
    • 23844494816 scopus 로고    scopus 로고
    • N-hydroxyurea and acyl nitroso compounds as nitroxyl (HNO) and nitric oxide (NO) donors
    • S. B. King, N-hydroxyurea and acyl nitroso compounds as nitroxyl (HNO) and nitric oxide (NO) donors, Current Topics in Medicinal Chemistry, vol. 5, no. 7, pp. 665-673, 2005.
    • (2005) Current Topics in Medicinal Chemistry , vol.5 , Issue.7 , pp. 665-673
    • King, S.B.1
  • 41
    • 84946479076 scopus 로고    scopus 로고
    • Newacyloxy nitroso compounds with improved water solubility and nitroxyl (HNO) release kinetics and inhibitors of platelet aggregation
    • H. A. H. Mohamed, M. Abdel-Aziz, A. A. Gamal El-Din, and S. B. King, Newacyloxy nitroso compounds with improved water solubility and nitroxyl (HNO) release kinetics and inhibitors of platelet aggregation, Bioorganic and Medicinal Chemistry, vol. 23, no. 17, pp. 6069-6077, 2015.
    • (2015) Bioorganic and Medicinal Chemistry , vol.23 , Issue.17 , pp. 6069-6077
    • Mohamed, H.A.H.1    Abdel-Aziz, M.2    Gamal El-Din, A.A.3    King, S.B.4
  • 42
    • 3242695442 scopus 로고    scopus 로고
    • Lewis acid-promoted hetero Diels-Alder cycloaddition of α-acetoxynitroso dienophiles
    • G. Calvet, M. Dussaussois, N. Blanchard, and C. Kouklovsky, Lewis acid-promoted hetero Diels-Alder cycloaddition of α-acetoxynitroso dienophiles, Organic Letters, vol. 6, no. 14, pp. 2449-2451, 2004.
    • (2004) Organic Letters , vol.6 , Issue.14 , pp. 2449-2451
    • Calvet, G.1    Dussaussois, M.2    Blanchard, N.3    Kouklovsky, C.4
  • 43
    • 79951834126 scopus 로고    scopus 로고
    • Acyloxy nitroso compounds as nitroxyl (HNO) donors: Kinetics, reactions with thiols, and vasodilation properties
    • M. E. Shoman, J. F. Dumond, T. S. Isbell et al., Acyloxy nitroso compounds as nitroxyl (HNO) donors: kinetics, reactions with thiols, and vasodilation properties, Journal of Medicinal Chemistry, vol. 54, no. 4, pp. 1059-1070, 2011.
    • (2011) Journal of Medicinal Chemistry , vol.54 , Issue.4 , pp. 1059-1070
    • Shoman, M.E.1    DuMond, J.F.2    Isbell, T.S.3
  • 45
    • 0042763556 scopus 로고    scopus 로고
    • The gasotransmitter role of hydrogen sulfide
    • R. Wang, The gasotransmitter role of hydrogen sulfide, Antioxidants and Redox Signaling, vol. 5, no. 4, pp. 493-501, 2003.
    • (2003) Antioxidants and Redox Signaling , vol.5 , Issue.4 , pp. 493-501
    • Wang, R.1
  • 46
    • 70349836129 scopus 로고    scopus 로고
    • A role for nitroxyl (HNO) as an endothelium-derived relaxing and hyperpolarizing factor in resistance arteries
    • K. L. Andrews, J. C. Irvine, M. Tare et al., A role for nitroxyl (HNO) as an endothelium-derived relaxing and hyperpolarizing factor in resistance arteries, British Journal of Pharmacology, vol. 157, no. 4, pp. 540-550, 2009.
    • (2009) British Journal of Pharmacology , vol.157 , Issue.4 , pp. 540-550
    • Andrews, K.L.1    Irvine, J.C.2    Tare, M.3
  • 47
    • 0034721839 scopus 로고    scopus 로고
    • Arginine conversion to nitroxide by tetrahydrobiopterin-free neuronal nitric-oxide synthase. Implications for mechanism
    • S. Adak, Q. Wang, and D. J. Stuehr, Arginine conversion to nitroxide by tetrahydrobiopterin-free neuronal nitric-oxide synthase. Implications for mechanism, Journal of Biological Chemistry, vol. 275, no. 43, pp. 33554-33561, 2000.
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.43 , pp. 33554-33561
    • Adak, S.1    Wang, Q.2    Stuehr, D.J.3
  • 48
    • 0027948425 scopus 로고
    • Formation of free nitric oxide from L-arginine by nitric oxide synthase: Direct enhancement of generation by superoxide dismutase
    • A. J. Hobbs, J. M. Fukuto, and L. J. Ignarro, Formation of free nitric oxide from L-arginine by nitric oxide synthase: direct enhancement of generation by superoxide dismutase, Proceedings of the National Academy of Sciences of the United States of America, vol. 91, no. 23, pp. 10992-10996, 1994.
    • (1994) Proceedings of the National Academy of Sciences of the United States of America , vol.91 , Issue.23 , pp. 10992-10996
    • Hobbs, A.J.1    Fukuto, J.M.2    Ignarro, L.J.3
  • 50
    • 0028898303 scopus 로고
    • Hydrogen peroxide-supported oxidation of NG-hydroxy-l-arginine by nitric oxide synthase
    • R. A. Pufahl, J. S. Wishnok, and M. A. Marletta, Hydrogen peroxide-supported oxidation of NG-hydroxy-l-arginine by nitric oxide synthase, Biochemistry, vol. 34, no. 6, pp. 1930-1941, 1995.
    • (1995) Biochemistry , vol.34 , Issue.6 , pp. 1930-1941
    • Pufahl, R.A.1    Wishnok, J.S.2    Marletta, M.A.3
  • 51
    • 0032480754 scopus 로고    scopus 로고
    • Reactions catalyzed by tetrahydrobiopterin-free nitric oxide synthase
    • K. M. Rusche, M. M. Spiering, and M. A. Marletta, Reactions catalyzed by tetrahydrobiopterin-free nitric oxide synthase, Biochemistry, vol. 37, no. 44, pp. 15503-15512, 1998.
    • (1998) Biochemistry , vol.37 , Issue.44 , pp. 15503-15512
    • Rusche, K.M.1    Spiering, M.M.2    Marletta, M.A.3
  • 52
    • 0027422994 scopus 로고
    • Peracid oxidation of an N-hydroxyguanidine compound: A chemical model for the oxidation of N omega-hydroxyl-Larginine by nitric oxide synthase
    • J. M. Fukuto, D. J. Stuehr, P. L. Feldman, M. P. Bova, and P. Wong, Peracid oxidation of an N-hydroxyguanidine compound: a chemical model for the oxidation of N omega-hydroxyl-Larginine by nitric oxide synthase, Journal of Medicinal Chemistry, vol. 36, no. 18, pp. 2666-2670, 1993.
    • (1993) Journal of Medicinal Chemistry , vol.36 , Issue.18 , pp. 2666-2670
    • Fukuto, J.M.1    Stuehr, D.J.2    Feldman, P.L.3    Bova, M.P.4    Wong, P.5
  • 53
    • 0032029785 scopus 로고    scopus 로고
    • The cytotoxicity of nitroxyl: Possible implications for the pathophysiological role of NO
    • D. A. Wink, M. Feelisch, J. Fukuto et al., The cytotoxicity of nitroxyl: possible implications for the pathophysiological role of NO, Archives of Biochemistry and Biophysics, vol. 351, no. 1, pp. 66-74, 1998.
    • (1998) Archives of Biochemistry and Biophysics , vol.351 , Issue.1 , pp. 66-74
    • Wink, D.A.1    Feelisch, M.2    Fukuto, J.3
  • 54
    • 0032524268 scopus 로고    scopus 로고
    • Reactions of nitric oxide with mitochondrial cytochrome c: A novel mechanism for the formation of nitroxyl anion and peroxynitrite
    • M. A. Sharpe and C. E. Cooper, Reactions of nitric oxide with mitochondrial cytochrome c: a novel mechanism for the formation of nitroxyl anion and peroxynitrite, Biochemical Journal, vol. 332, part 1, pp. 9-19, 1998.
    • (1998) Biochemical Journal , vol.332 , Issue.PART 1 , pp. 9-19
    • Sharpe, M.A.1    Cooper, C.E.2
  • 55
    • 0842310589 scopus 로고    scopus 로고
    • Xanthine oxidase converts nitric oxide to nitroxyl that inactivates the enzyme
    • M. Saleem and H. Ohshima, Xanthine oxidase converts nitric oxide to nitroxyl that inactivates the enzyme, Biochemical and Biophysical Research Communications, vol. 315, no. 2, pp. 455-462, 2004.
    • (2004) Biochemical and Biophysical Research Communications , vol.315 , Issue.2 , pp. 455-462
    • Saleem, M.1    Ohshima, H.2
  • 56
    • 0033231363 scopus 로고    scopus 로고
    • Exposure ofMn and FeSODs, but not Cu/ZnSOD, to NO leads to nitrosonium and nitroxyl ions generation which cause enzyme modification and inactivation: An in vitro study
    • V. Niketic, S. Stojanovic, A. Nikolic, M. Spasic, and A. M. Michelson, Exposure ofMn and FeSODs, but not Cu/ZnSOD, to NO leads to nitrosonium and nitroxyl ions generation which cause enzyme modification and inactivation: an in vitro study, Free Radical Biology andMedicine, vol. 27, no. 9-10, pp. 992-996, 1999.
    • (1999) Free Radical Biology AndMedicine , vol.27 , Issue.9-10 , pp. 992-996
    • Niketic, V.1    Stojanovic, S.2    Nikolic, A.3    Spasic, M.4    Michelson, A.M.5
  • 57
    • 0032960205 scopus 로고    scopus 로고
    • The reaction of nitric oxide with ubiquinol: Kinetic properties and biological significance
    • J. J. Poderoso, M. C. Carreras, F. Schopfer et al., The reaction of nitric oxide with ubiquinol: kinetic properties and biological significance, FreeRadical Biology andMedicine, vol. 26, no. 7-8, pp. 925-935, 1999.
    • (1999) FreeRadical Biology AndMedicine , vol.26 , Issue.7-8 , pp. 925-935
    • Poderoso, J.J.1    Carreras, M.C.2    Schopfer, F.3
  • 58
    • 77953514816 scopus 로고    scopus 로고
    • Oxidative heme proteinmediated nitroxyl (HNO) generation
    • J. A. Reisz, E. Bechtold, and S. B. King, Oxidative heme proteinmediated nitroxyl (HNO) generation, Dalton Transactions, vol. 39, no. 22, pp. 5203-5212, 2010.
    • (2010) Dalton Transactions , vol.39 , Issue.22 , pp. 5203-5212
    • Reisz, J.A.1    Bechtold, E.2    King, S.B.3
  • 59
    • 0000322203 scopus 로고
    • Oxidation and reduction of hemoproteins by trioxodinitrate(II). The role of nitrosyl hydride and nitrite
    • M. P. Doyle, S. N. Mahapatro, R. D. Broene, and J. K. Guy, Oxidation and reduction of hemoproteins by trioxodinitrate(II). The role of nitrosyl hydride and nitrite, Journal of the American Chemical Society, vol. 110, no. 2, pp. 593-599, 1988.
    • (1988) Journal of the American Chemical Society , vol.110 , Issue.2 , pp. 593-599
    • Doyle, M.P.1    Mahapatro, S.N.2    Broene, R.D.3    Guy, J.K.4
  • 60
    • 0033958479 scopus 로고    scopus 로고
    • Reaction of nitroxyl, an aldehyde dehydrogenase inhibitor, with N-acetyl-L-cysteine
    • D. W. Shoeman, F. N. Shirota, E. G. DeMaster, and H. T. Nagasawa, Reaction of nitroxyl, an aldehyde dehydrogenase inhibitor, with N-acetyl-L-cysteine, Alcohol, vol. 20, no. 1, pp. 55-59, 2000.
    • (2000) Alcohol , vol.20 , Issue.1 , pp. 55-59
    • Shoeman, D.W.1    Shirota, F.N.2    DeMaster, E.G.3    Nagasawa, H.T.4
  • 61
    • 0026763915 scopus 로고
    • Oxidation of dithiothreitol during turnover of nitric oxide reductase: Evidence for generation of nitroxyl with the enzyme from Paracoccus denitrificans
    • T. Turk and T. C. Hollocher, Oxidation of dithiothreitol during turnover of nitric oxide reductase: evidence for generation of nitroxyl with the enzyme from Paracoccus denitrificans, Biochemical and Biophysical Research Communications, vol. 183, no. 3, pp. 983-988, 1992.
    • (1992) Biochemical and Biophysical Research Communications , vol.183 , Issue.3 , pp. 983-988
    • Turk, T.1    Hollocher, T.C.2
  • 63
    • 27144507452 scopus 로고    scopus 로고
    • Mass spectrometric analysis of nitroxyl-mediated protein modification: Comparison of products formed with free and protein-based cysteines
    • B. Shen and A. M. English, Mass spectrometric analysis of nitroxyl-mediated protein modification: comparison of products formed with free and protein-based cysteines, Biochemistry, vol. 44, no. 42, pp. 14030-14044, 2005.
    • (2005) Biochemistry , vol.44 , Issue.42 , pp. 14030-14044
    • Shen, B.1    English, A.M.2
  • 64
    • 67449105855 scopus 로고    scopus 로고
    • Identification of nitroxyl-induced modifications in human platelet proteins using a novel mass spectrometric detection method
    • M. D. Hoffman, G. M. Walsh, J. C. Rogalski, and J. Kast, Identification of nitroxyl-induced modifications in human platelet proteins using a novel mass spectrometric detection method, Molecular and Cellular Proteomics, vol. 8, no. 5, pp. 887-903, 2009.
    • (2009) Molecular and Cellular Proteomics , vol.8 , Issue.5 , pp. 887-903
    • Hoffman, M.D.1    Walsh, G.M.2    Rogalski, J.C.3    Kast, J.4
  • 65
    • 84884232961 scopus 로고    scopus 로고
    • Direct and nitroxyl (HNO)-mediated reactions of acyloxy nitroso compounds with the thiol-containing proteins glyceraldehyde 3-phosphate dehydrogenase and alkyl hydroperoxide reductase subunit C
    • S. Mitroka, M. E. Shoman, J. F. DuMond et al., Direct and nitroxyl (HNO)-mediated reactions of acyloxy nitroso compounds with the thiol-containing proteins glyceraldehyde 3-phosphate dehydrogenase and alkyl hydroperoxide reductase subunit C, Journal of Medicinal Chemistry, vol. 56, no. 17, pp. 6583-6592, 2013.
    • (2013) Journal of Medicinal Chemistry , vol.56 , Issue.17 , pp. 6583-6592
    • Mitroka, S.1    Shoman, M.E.2    DuMond, J.F.3
  • 67
    • 77953520252 scopus 로고    scopus 로고
    • Computational investigation of the reaction mechanisms of nitroxyl and thiols
    • M. P. Sherman, W. R. Grither, and R. D. McCulla, Computational investigation of the reaction mechanisms of nitroxyl and thiols, Journal of Organic Chemistry, vol. 75, no. 12, pp. 4014-4024, 2010.
    • (2010) Journal of Organic Chemistry , vol.75 , Issue.12 , pp. 4014-4024
    • Sherman, M.P.1    Grither, W.R.2    McCulla, R.D.3
  • 68
    • 10644245185 scopus 로고    scopus 로고
    • Coordination chemistry of the HNO ligand with hemes and synthetic coordination complexes
    • P. J. Farmer and F. Sulc, Coordination chemistry of the HNO ligand with hemes and synthetic coordination complexes, Journal of Inorganic Biochemistry, vol. 99, no. 1, pp. 166-184, 2005.
    • (2005) Journal of Inorganic Biochemistry , vol.99 , Issue.1 , pp. 166-184
    • Farmer, P.J.1    Sulc, F.2
  • 69
    • 0037245344 scopus 로고    scopus 로고
    • Comparison of the reactivity of nitric oxide and nitroxyl with heme proteins: A chemical discussion of the differential biological effects of these redox related products of NOS
    • K. M. Miranda, R. W. Nims, D. D. Thomas et al., Comparison of the reactivity of nitric oxide and nitroxyl with heme proteins: a chemical discussion of the differential biological effects of these redox related products of NOS, Journal of Inorganic Biochemistry, vol. 93, no. 1-2, pp. 52-60, 2003.
    • (2003) Journal of Inorganic Biochemistry , vol.93 , Issue.1-2 , pp. 52-60
    • Miranda, K.M.1    Nims, R.W.2    Thomas, D.D.3
  • 70
    • 3042554283 scopus 로고    scopus 로고
    • Catalase-mediated nitric oxide formation from hydroxyurea
    • J. Huang, D. B. Kim-Shapiro, and S. B. King, Catalase-mediated nitric oxide formation from hydroxyurea, Journal of Medicinal Chemistry, vol. 47, no. 14, pp. 3495-3501, 2004.
    • (2004) Journal of Medicinal Chemistry , vol.47 , Issue.14 , pp. 3495-3501
    • Huang, J.1    Kim-Shapiro, D.B.2    King, S.B.3
  • 72
    • 33845434556 scopus 로고    scopus 로고
    • Consequences ofMnSOD interactions with nitric oxide: Nitric oxide dismutation and the generation of peroxynitrite and hydrogen peroxide
    • M. R. Filipovic, D. Stanic, S. Raicevic, M. Spasic, and V. Niketic, Consequences ofMnSOD interactions with nitric oxide: nitric oxide dismutation and the generation of peroxynitrite and hydrogen peroxide, Free Radical Research, vol. 41, no. 1, pp. 62-72, 2007.
    • (2007) Free Radical Research , vol.41 , Issue.1 , pp. 62-72
    • Filipovic, M.R.1    Stanic, D.2    Raicevic, S.3    Spasic, M.4    Niketic, V.5
  • 73
    • 0041292497 scopus 로고
    • Organophosphorus compounds. XXIV. The reaction of triphenylphosphine and trialkyl phosphites with α-nitroso-β-naphthol
    • M. M. Sidky, F. M. Soliman, and R. Shabana, Organophosphorus compounds. XXIV. The reaction of triphenylphosphine and trialkyl phosphites with α-nitroso-β-naphthol, Egyptian Journal of Chemistry, vol. 21, pp. 29-35, 1980.
    • (1980) Egyptian Journal of Chemistry , vol.21 , pp. 29-35
    • Sidky, M.M.1    Soliman, F.M.2    Shabana, R.3
  • 74
    • 77951137130 scopus 로고    scopus 로고
    • Water-soluble triarylphosphines as biomarkers for protein S-nitrosation
    • E. Bechtold, J. A. Reisz, C. Klomsiri et al., Water-soluble triarylphosphines as biomarkers for protein S-nitrosation, ACS Chemical Biology, vol. 5, no. 4, pp. 405-414, 2010.
    • (2010) ACS Chemical Biology , vol.5 , Issue.4 , pp. 405-414
    • Bechtold, E.1    Reisz, J.A.2    Klomsiri, C.3
  • 75
    • 13344283840 scopus 로고
    • Zur desoxygenierung von tritylthionitrit
    • M. Haake, Zur desoxygenierung von tritylthionitrit, Tetrahedron Letters, vol. 13, no. 33, pp. 3405-3408, 1972.
    • (1972) Tetrahedron Letters , vol.13 , Issue.33 , pp. 3405-3408
    • Haake, M.1
  • 76
    • 67649506367 scopus 로고    scopus 로고
    • Reductive phosphine-mediated ligation of nitroxyl (HNO)
    • J. A. Reisz, E. B. Klorlg, M. W. Wright, and S. B. King, Reductive phosphine-mediated ligation of nitroxyl (HNO), Organic Letters, vol. 11, no. 13, pp. 2719-2721, 2009.
    • (2009) Organic Letters , vol.11 , Issue.13 , pp. 2719-2721
    • Reisz, J.A.1    Klorlg, E.B.2    Wright, M.W.3    King, S.B.4
  • 77
    • 0037095633 scopus 로고    scopus 로고
    • Further evidence for distinct reactive intermediates from nitroxyl and peroxynitrite: Effects of buffer composition on the chemistry of Angelis salt and synthetic peroxynitrite
    • K. M. Miranda, Y. K-I, M. G. Espey et al., Further evidence for distinct reactive intermediates from nitroxyl and peroxynitrite: effects of buffer composition on the chemistry of Angelis salt and synthetic peroxynitrite, Archives of Biochemistry and Biophysics, vol. 401, no. 2, pp. 134-144, 2002.
    • (2002) Archives of Biochemistry and Biophysics , vol.401 , Issue.2 , pp. 134-144
    • Miranda, K.M.1    Ki, Y.2    Espey, M.G.3
  • 78
    • 19944434346 scopus 로고    scopus 로고
    • Mechanism of aerobic decomposition of Angelis salt (Sodium Trioxodinitrate) at physiological pH
    • K. M. Miranda, A. S. Dutton, L. A. Ridnour et al., Mechanism of aerobic decomposition of Angelis salt (Sodium Trioxodinitrate) at physiological pH, Journal of the American Chemical Society, vol. 127, no. 2, pp. 722-731, 2005.
    • (2005) Journal of the American Chemical Society , vol.127 , Issue.2 , pp. 722-731
    • Miranda, K.M.1    Dutton, A.S.2    Ridnour, L.A.3
  • 80
    • 0042062298 scopus 로고    scopus 로고
    • Oxidation of N-hydroxyguanidines by copper(II): Model systems for elucidating the physiological chemistry of the nitric oxide biosynthetic intermediate N-hydroxyl-L-arginine
    • J. Y. Cho, A. Dutton, T. Miller, K. N. Houk, and J. M. Fukuto, Oxidation of N-hydroxyguanidines by copper(II): model systems for elucidating the physiological chemistry of the nitric oxide biosynthetic intermediate N-hydroxyl-L-arginine, Archives of Biochemistry and Biophysics, vol. 417, no. 1, pp. 65-76, 2003.
    • (2003) Archives of Biochemistry and Biophysics , vol.417 , Issue.1 , pp. 65-76
    • Cho, J.Y.1    Dutton, A.2    Miller, T.3    Houk, K.N.4    Fukuto, J.M.5
  • 81
    • 0028232689 scopus 로고
    • Bioassay discrimination between nitric oxide (NO) and nitroxyl (NO-) using L-cysteine
    • R. Z. Pino and M. Feelisch, Bioassay discrimination between nitric oxide (NO) and nitroxyl (NO-) using L-cysteine, Biochemical and Biophysical Research Communications, vol. 201, no. 1, pp. 54-62, 1994.
    • (1994) Biochemical and Biophysical Research Communications , vol.201 , Issue.1 , pp. 54-62
    • Pino, R.Z.1    Feelisch, M.2
  • 82
    • 0034022918 scopus 로고    scopus 로고
    • Electron-paramagnetic resonance spectroscopy usingN-methyl-D-glucamine dithiocarbamate iron cannot discriminate between nitric oxide and nitroxyl: Implications for the detection of reaction products for nitric oxide synthase
    • A. M. Komarov, D. A. Wink, M. Feelisch, and H. H. H. W. Schmidt, Electron-paramagnetic resonance spectroscopy usingN-methyl-D-glucamine dithiocarbamate iron cannot discriminate between nitric oxide and nitroxyl: implications for the detection of reaction products for nitric oxide synthase, Free Radical Biology and Medicine, vol. 28, no. 5, pp. 739-742, 2000.
    • (2000) Free Radical Biology and Medicine , vol.28 , Issue.5 , pp. 739-742
    • Komarov, A.M.1    Wink, D.A.2    Feelisch, M.3    Schmidt, H.H.H.W.4
  • 83
    • 0034667724 scopus 로고    scopus 로고
    • Electron paramagnetic resonance spectroscopy with N-methyl-D-glucamine dithiocarbamate iron complexes distinguishes nitric oxide and nitroxyl anion in a redox-dependent manner: Applications in identifying nitrogen monoxide products from nitric oxide synthase
    • Y. Xia, A. J. Cardounel, A. F. Vanin, and J. L. Zweier, Electron paramagnetic resonance spectroscopy with N-methyl-D-glucamine dithiocarbamate iron complexes distinguishes nitric oxide and nitroxyl anion in a redox-dependent manner: applications in identifying nitrogen monoxide products from nitric oxide synthase, Free Radical Biology and Medicine, vol. 29, no. 8, pp. 793-797, 2000.
    • (2000) Free Radical Biology and Medicine , vol.29 , Issue.8 , pp. 793-797
    • Xia, Y.1    Cardounel, A.J.2    Vanin, A.F.3    Zweier, J.L.4
  • 84
    • 0035910389 scopus 로고    scopus 로고
    • Unique oxidative mechanisms for the reactive nitrogen oxide species, nitroxyl anion
    • K. M. Miranda, M. G. Espey, K. Yamada et al., Unique oxidative mechanisms for the reactive nitrogen oxide species, nitroxyl anion, The Journal of Biological Chemistry, vol. 276, no. 3, pp. 1720-1727, 2001.
    • (2001) The Journal of Biological Chemistry , vol.276 , Issue.3 , pp. 1720-1727
    • Miranda, K.M.1    Espey, M.G.2    Yamada, K.3
  • 85
    • 0032004515 scopus 로고    scopus 로고
    • The reaction of nitroxyl (HNO) with nitrosobenzene gives cupferron (NNitrosophenylhydroxylamine)
    • D. W. Shoeman and H. T. Nagasawa, The reaction of nitroxyl (HNO) with nitrosobenzene gives cupferron (NNitrosophenylhydroxylamine), Nitric Oxide, vol. 2, no. 1, pp. 66-72, 1998.
    • (1998) Nitric Oxide , vol.2 , Issue.1 , pp. 66-72
    • Shoeman, D.W.1    Nagasawa, H.T.2
  • 86
    • 79960853659 scopus 로고    scopus 로고
    • Rapid and selective nitroxyl (HNO) trapping by phosphines: Kinetics and new aqueous ligations for HNO detection and quantitation
    • J. A. Reisz, C. N. Zink, and S. B. King, Rapid and selective nitroxyl (HNO) trapping by phosphines: kinetics and new aqueous ligations for HNO detection and quantitation, Journal of the American Chemical Society, vol. 133, no. 30, pp. 11675-11685, 2011.
    • (2011) Journal of the American Chemical Society , vol.133 , Issue.30 , pp. 11675-11685
    • Reisz, J.A.1    Zink, C.N.2    King, S.B.3
  • 88
    • 80053303135 scopus 로고    scopus 로고
    • Detection of nitroxyl (HNO) by a prefluorescent probe
    • M. R. Cline and J. P. Toscano, Detection of nitroxyl (HNO) by a prefluorescent probe, Journal of Physical Organic Chemistry, vol. 24, no. 10, pp. 993-998, 2011.
    • (2011) Journal of Physical Organic Chemistry , vol.24 , Issue.10 , pp. 993-998
    • Cline, M.R.1    Toscano, J.P.2
  • 91
    • 0026483146 scopus 로고
    • The pharmacological activity of nitroxyl: A potent vasodilator with activity similar to nitric oxide and/or endothelium-derived relaxing factor
    • J. M. Fukuto, K. Chiang, R. Hszieh, P. Wong, and G. Chaudhuri, The pharmacological activity of nitroxyl: a potent vasodilator with activity similar to nitric oxide and/or endothelium-derived relaxing factor, Journal of Pharmacology and Experimental Therapeutics, vol. 263, no. 2, pp. 546-551, 1992.
    • (1992) Journal of Pharmacology and Experimental Therapeutics , vol.263 , Issue.2 , pp. 546-551
    • Fukuto, J.M.1    Chiang, K.2    Hszieh, R.3    Wong, P.4    Chaudhuri, G.5
  • 92
    • 0034779669 scopus 로고    scopus 로고
    • Vascular smooth muscle relaxation mediated by nitric oxide donors: A comparison with acetylcholine, nitric oxide and nitroxyl ion
    • J. C. Wanstall, T. K. Jeffery, A. Gambino, F. Lovren, and C. R. Triggle, Vascular smooth muscle relaxation mediated by nitric oxide donors: a comparison with acetylcholine, nitric oxide and nitroxyl ion, British Journal of Pharmacology, vol. 134, no. 3, pp. 463-472, 2001.
    • (2001) British Journal of Pharmacology , vol.134 , Issue.3 , pp. 463-472
    • Wanstall, J.C.1    Jeffery, T.K.2    Gambino, A.3    Lovren, F.4    Triggle, C.R.5
  • 93
    • 0033979144 scopus 로고    scopus 로고
    • Differential actions of Lcysteine on responses to nitric oxide, nitroxyl anions and EDRF in the rat aorta
    • A. Ellis, C. G. Li, and M. J. Rand, Differential actions of Lcysteine on responses to nitric oxide, nitroxyl anions and EDRF in the rat aorta, British Journal of Pharmacology, vol. 129, no. 2, pp. 315-322, 2000.
    • (2000) British Journal of Pharmacology , vol.129 , Issue.2 , pp. 315-322
    • Ellis, A.1    Li, C.G.2    Rand, M.J.3
  • 94
    • 0038796529 scopus 로고    scopus 로고
    • NOactivates soluble guanylate cyclase andKv channels to vasodilate resistance arteries
    • J. C. Irvine, J. L. Favaloro, and B. K. Kemp-Harper, NOactivates soluble guanylate cyclase andKv channels to vasodilate resistance arteries, Hypertension, vol. 41, no. 6, pp. 1301-1307, 2003.
    • (2003) Hypertension , vol.41 , Issue.6 , pp. 1301-1307
    • Irvine, J.C.1    Favaloro, J.L.2    Kemp-Harper, B.K.3
  • 95
    • 33846056511 scopus 로고    scopus 로고
    • The nitroxyl anion (HNO) is a potent dilator of rat coronary vasculature
    • J. L. Favaloro and B. K. Kemp-Harper, The nitroxyl anion (HNO) is a potent dilator of rat coronary vasculature, Cardiovascular Research, vol. 73, no. 3, pp. 587-596, 2007.
    • (2007) Cardiovascular Research , vol.73 , Issue.3 , pp. 587-596
    • Favaloro, J.L.1    Kemp-Harper, B.K.2
  • 96
    • 0035798372 scopus 로고    scopus 로고
    • Comparison of responses to novel nitric oxide donors in the feline pulmonary vascular bed
    • B. J. De Witt, J. R. Marrone, A. D. Kaye, L. K. Keefer, and P. J. Kadowitz, Comparison of responses to novel nitric oxide donors in the feline pulmonary vascular bed, European Journal of Pharmacology, vol. 430, no. 2-3, pp. 311-315, 2001.
    • (2001) European Journal of Pharmacology , vol.430 , Issue.2-3 , pp. 311-315
    • De Witt, B.J.1    Marrone, J.R.2    Kaye, A.D.3    Keefer, L.K.4    Kadowitz, P.J.5
  • 101
    • 0031435306 scopus 로고    scopus 로고
    • Soluble guanylate cyclase: The forgotten sibling
    • A. J. Hobbs, Soluble guanylate cyclase: the forgotten sibling, Trends in Pharmacological Sciences, vol. 18, no. 12, pp. 484-491, 1997.
    • (1997) Trends in Pharmacological Sciences , vol.18 , Issue.12 , pp. 484-491
    • Hobbs, A.J.1
  • 102
    • 0029664587 scopus 로고    scopus 로고
    • Nitric oxide (NO), the only nitrogen monoxide redox form capable of activating soluble guanylyl cyclase
    • E. A. Dierks and J. N. Burstyn, Nitric oxide (NO), the only nitrogen monoxide redox form capable of activating soluble guanylyl cyclase, Biochemical Pharmacology, vol. 51, no. 12, pp. 1593-1600, 1996.
    • (1996) Biochemical Pharmacology , vol.51 , Issue.12 , pp. 1593-1600
    • Dierks, E.A.1    Burstyn, J.N.2
  • 103
    • 34047216951 scopus 로고    scopus 로고
    • Nitroxyl anion donor, Angelis salt, does not develop tolerance in rat isolated aortae
    • J. C. Irvine, J. L. Favaloro, R. E. Widdop, and B. K. Kemp-Harper, Nitroxyl anion donor, Angelis salt, does not develop tolerance in rat isolated aortae, Hypertension, vol. 49, no. 4, pp. 885-892, 2007.
    • (2007) Hypertension , vol.49 , Issue.4 , pp. 885-892
    • Irvine, J.C.1    Favaloro, J.L.2    Widdop, R.E.3    Kemp-Harper, B.K.4
  • 104
    • 33748302123 scopus 로고    scopus 로고
    • Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vessels
    • J.-P. Stasch, P. M. Schmidt, P. I. Nedvetsky et al., Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vessels, The Journal of Clinical Investigation, vol. 116, no. 9, pp. 2552-2561, 2006.
    • (2006) The Journal of Clinical Investigation , vol.116 , Issue.9 , pp. 2552-2561
    • Stasch, J.-P.1    Schmidt, P.M.2    Nedvetsky, P.I.3
  • 105
    • 70350469954 scopus 로고    scopus 로고
    • Mechanisms underlying activation of soluble guanylate cyclase by the nitroxyl donor Angelis salt
    • A. Zeller, M. V. Wenzl, M. Beretta et al., Mechanisms underlying activation of soluble guanylate cyclase by the nitroxyl donor Angelis salt, Molecular Pharmacology, vol. 76, no. 5, pp. 1115-1122, 2009.
    • (2009) Molecular Pharmacology , vol.76 , Issue.5 , pp. 1115-1122
    • Zeller, A.1    Wenzl, M.V.2    Beretta, M.3
  • 106
    • 3042597423 scopus 로고    scopus 로고
    • Vascular actions of calcitonin gene-related peptide and adrenomedullin
    • S. D. Brain and A. D. Grant, Vascular actions of calcitonin gene-related peptide and adrenomedullin, Physiological Reviews, vol. 84, no. 3, pp. 903-934, 2004.
    • (2004) Physiological Reviews , vol.84 , Issue.3 , pp. 903-934
    • Brain, S.D.1    Grant, A.D.2
  • 107
    • 84904490728 scopus 로고    scopus 로고
    • H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO-TRPA1-CGRP signalling pathway
    • article 4381, 17 pages
    • M. Eberhardt, M. Dux, B. Namer et al., H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO-TRPA1-CGRP signalling pathway, Nature Communications, vol. 5, article 4381, 17 pages, 2014.
    • (2014) Nature Communications , vol.5
    • Eberhardt, M.1    Dux, M.2    Namer, B.3
  • 108
    • 0031853894 scopus 로고    scopus 로고
    • Nitric oxide (NO)-induced activation of large conductance Ca2+-dependent K+ channels (BK(Ca)) in smooth muscle cells isolated from the rat mesenteric artery
    • D. K. Mistry and C. J. Garland, Nitric oxide (NO)-induced activation of large conductance Ca2+-dependent K+ channels (BK(Ca)) in smooth muscle cells isolated from the rat mesenteric artery, British Journal of Pharmacology, vol. 124, no. 6, pp. 1131-1140, 1998.
    • (1998) British Journal of Pharmacology , vol.124 , Issue.6 , pp. 1131-1140
    • Mistry, D.K.1    Garland, C.J.2
  • 110
    • 33846035704 scopus 로고    scopus 로고
    • Nitroxyl improves cellular heart function by directly enhancing cardiac sarcoplasmic reticulumCa2+ cycling
    • C. G. Tocchetti, W. Wang, J. P. Froehlich et al., Nitroxyl improves cellular heart function by directly enhancing cardiac sarcoplasmic reticulumCa2+ cycling, Circulation Research, vol. 100, no. 1, pp. 96-104, 2007.
    • (2007) Circulation Research , vol.100 , Issue.1 , pp. 96-104
    • Tocchetti, C.G.1    Wang, W.2    Froehlich, J.P.3
  • 111
    • 57649128299 scopus 로고    scopus 로고
    • Phospholamban thiols play a central role in activation of the cardiac muscle sarcoplasmic reticulum calcium pump by nitroxyl
    • J. P. Froehlich, J. E. Mahaney, G. Keceli et al., Phospholamban thiols play a central role in activation of the cardiac muscle sarcoplasmic reticulum calcium pump by nitroxyl, Biochemistry, vol. 47, no. 50, pp. 13150-13152, 2008.
    • (2008) Biochemistry , vol.47 , Issue.50 , pp. 13150-13152
    • Froehlich, J.P.1    Mahaney, J.E.2    Keceli, G.3
  • 112
    • 34249853701 scopus 로고    scopus 로고
    • Nitroxyl increases force development in rat cardiac muscle
    • T. Dai, Y. Tian, C. G. Tocchetti et al., Nitroxyl increases force development in rat cardiac muscle, Journal of Physiology, vol. 580, no. 3, pp. 951-960, 2007.
    • (2007) Journal of Physiology , vol.580 , Issue.3 , pp. 951-960
    • Dai, T.1    Tian, Y.2    Tocchetti, C.G.3
  • 113
    • 12244282420 scopus 로고    scopus 로고
    • Nitroxyl affords thiol-sensitive myocardial protective effects akin to early preconditioning
    • P. Pagliaro, D. Mancardi, R. Rastaldo et al., Nitroxyl affords thiol-sensitive myocardial protective effects akin to early preconditioning, Free Radical Biology and Medicine, vol. 34, no. 1, pp. 33-43, 2003.
    • (2003) Free Radical Biology and Medicine , vol.34 , Issue.1 , pp. 33-43
    • Pagliaro, P.1    Mancardi, D.2    Rastaldo, R.3
  • 114
    • 2342614194 scopus 로고    scopus 로고
    • Mechanisms of the interaction of nitroxyl with mitochondria
    • S. Shiva, J. H. Crawford, A. Ramachandran et al., Mechanisms of the interaction of nitroxyl with mitochondria, Biochemical Journal, vol. 379, no. 2, pp. 359-366, 2004.
    • (2004) Biochemical Journal , vol.379 , Issue.2 , pp. 359-366
    • Shiva, S.1    Crawford, J.H.2    Ramachandran, A.3
  • 115
    • 0037053106 scopus 로고    scopus 로고
    • The cardioprotection of calcitonin generelated peptide-mediated preconditioning
    • Y.-J. Li and J. Peng, The cardioprotection of calcitonin generelated peptide-mediated preconditioning, European Journal of Pharmacology, vol. 442, no. 3, pp. 173-177, 2002.
    • (2002) European Journal of Pharmacology , vol.442 , Issue.3 , pp. 173-177
    • Li, Y.-J.1    Peng, J.2
  • 116
    • 84938545459 scopus 로고    scopus 로고
    • Chronic administration of the nitroxyl donor 1-nitrosocyclo hexyl acetate limits left ventricular diastolic dysfunction in a mouse model of diabetes mellitus in vivo
    • N. Cao, Y. G. Wong, S. Rosli et al., Chronic administration of the nitroxyl donor 1-nitrosocyclo hexyl acetate limits left ventricular diastolic dysfunction in a mouse model of diabetes mellitus in vivo, Circulation:Heart Failure, vol. 8, no. 3, pp. 572-581, 2015.
    • (2015) Circulation:Heart Failure , vol.8 , Issue.3 , pp. 572-581
    • Cao, N.1    Wong, Y.G.2    Rosli, S.3
  • 118
    • 40349085661 scopus 로고    scopus 로고
    • Nitroxyl inhibits breast tumor growth and angiogenesis
    • A. J. Norris, M. R. Sartippour, M. Lu et al., Nitroxyl inhibits breast tumor growth and angiogenesis, International Journal of Cancer, vol. 122, no. 8, pp. 1905-1910, 2008.
    • (2008) International Journal of Cancer , vol.122 , Issue.8 , pp. 1905-1910
    • Norris, A.J.1    Sartippour, M.R.2    Lu, M.3
  • 120
    • 34548400837 scopus 로고    scopus 로고
    • The inhibition of glyceraldehyde-3-phosphate dehydrogenase by nitroxyl (HNO)
    • B. E. Lopez, D. A. Wink, and J. M. Fukuto, The inhibition of glyceraldehyde-3-phosphate dehydrogenase by nitroxyl (HNO), Archives of Biochemistry and Biophysics, vol. 465, no. 2, pp. 430-436, 2007.
    • (2007) Archives of Biochemistry and Biophysics , vol.465 , Issue.2 , pp. 430-436
    • Lopez, B.E.1    Wink, D.A.2    Fukuto, J.M.3
  • 121
    • 27944509575 scopus 로고    scopus 로고
    • FXYD3 is over expressed in pancreatic ductal adenocarcinoma and influences pancreatic cancer cell growth
    • H. Kayed, J. Kleeff, A. Kolb et al., FXYD3 is over expressed in pancreatic ductal adenocarcinoma and influences pancreatic cancer cell growth, International Journal of Cancer, vol. 118, no. 1, pp. 43-54, 2006.
    • (2006) International Journal of Cancer , vol.118 , Issue.1 , pp. 43-54
    • Kayed, H.1    Kleeff, J.2    Kolb, A.3
  • 122
    • 3843134200 scopus 로고    scopus 로고
    • Up-regulated expression of the MAT-8 gene in prostate cancer and its siRNA-mediated inhibition of expression induces a decrease in proliferation of human prostate carcinoma cells
    • J. P. Froehlich and N. Paolocci, Up-regulated expression of the MAT-8 gene in prostate cancer and its siRNA-mediated inhibition of expression induces a decrease in proliferation of human prostate carcinoma cells, International Journal of Oncology, vol. 24, no. 1, pp. 97-105, 2004.
    • (2004) International Journal of Oncology , vol.24 , Issue.1 , pp. 97-105
    • Froehlich, J.P.1    Paolocci, N.2
  • 123
    • 0034662757 scopus 로고    scopus 로고
    • The FXYD gene family of small ion transport regulators or channels: CDNA sequence, protein signature sequence, and expression
    • K. J. Sweadner and E. Rael, The FXYD gene family of small ion transport regulators or channels: cDNA sequence, protein signature sequence, and expression, Genomics, vol. 68, no. 1, pp. 41-56, 2000.
    • (2000) Genomics , vol.68 , Issue.1 , pp. 41-56
    • Sweadner, K.J.1    Rael, E.2
  • 124
    • 0032910169 scopus 로고    scopus 로고
    • Apoptosis control by death and decoy receptors
    • A. Ashkenazi and V. M. Dixit, Apoptosis control by death and decoy receptors, Current Opinion in Cell Biology, vol. 11, no. 2, pp. 255-260, 1999.
    • (1999) Current Opinion in Cell Biology , vol.11 , Issue.2 , pp. 255-260
    • Ashkenazi, A.1    Dixit, V.M.2
  • 127
    • 0033213383 scopus 로고    scopus 로고
    • Attenuation of NMDA receptor activity and neurotoxicity by nitroxyl anion, NO
    • W.-K. Kim, Y.-B. Choi, P. V. Rayudu et al., Attenuation of NMDA receptor activity and neurotoxicity by nitroxyl anion, NO, Neuron, vol. 24, no. 2, pp. 461-469, 1999.
    • (1999) Neuron , vol.24 , Issue.2 , pp. 461-469
    • Kim, W.-K.1    Choi, Y.-B.2    Rayudu, P.V.3
  • 129
    • 15244350287 scopus 로고    scopus 로고
    • Nitric oxiderelated species-induced protein oxidation: Reversible, irreversible, and protective effects on enzyme function of papain
    • A. J. Vaananen, E. Kankuri, and P. Rauhala, Nitric oxiderelated species-induced protein oxidation: reversible, irreversible, and protective effects on enzyme function of papain, Free Radical Biology and Medicine, vol. 38, no. 8, pp. 1102-1111, 2005.
    • (2005) Free Radical Biology and Medicine , vol.38 , Issue.8 , pp. 1102-1111
    • Vaananen, A.J.1    Kankuri, E.2    Rauhala, P.3
  • 130
    • 54949147940 scopus 로고    scopus 로고
    • Persistent susceptibility of cathepsin B to irreversible inhibition by nitroxyl (HNO) in the presence of endogenous nitric oxide
    • A. J. Vaananen, P. Salmenpera, M. Hukkanen et al., Persistent susceptibility of cathepsin B to irreversible inhibition by nitroxyl (HNO) in the presence of endogenous nitric oxide, Free Radical Biology and Medicine, vol. 45, no. 6, pp. 749-755, 2008.
    • (2008) Free Radical Biology and Medicine , vol.45 , Issue.6 , pp. 749-755
    • Vaananen, A.J.1    Salmenpera, P.2    Hukkanen, M.3
  • 131
    • 33745058367 scopus 로고    scopus 로고
    • Cathepsin B is a differentiation-resistant target for nitroxyl (HNO) in THP-1 monocyte/macrophages
    • A. J. Vaananen, P. Salmenpera, M. Hukkanen, P. Rauhala, and E. Kankuri, Cathepsin B is a differentiation-resistant target for nitroxyl (HNO) in THP-1 monocyte/macrophages, Free Radical Biology and Medicine, vol. 41, no. 1, pp. 120-131, 2006.
    • (2006) Free Radical Biology and Medicine , vol.41 , Issue.1 , pp. 120-131
    • Vaananen, A.J.1    Salmenpera, P.2    Hukkanen, M.3    Rauhala, P.4    Kankuri, E.5
  • 132
    • 0037328556 scopus 로고    scopus 로고
    • Nitroxyl-mediated disruption of thiol proteins: Inhibition of the yeast transcription factor Ace1
    • N. M. Cook, M. Shinyashiki, M. I. Jackson, F. A. Leal, and J. M. Fukuto, Nitroxyl-mediated disruption of thiol proteins: inhibition of the yeast transcription factor Ace1, Archives of Biochemistry and Biophysics, vol. 410, no. 1, pp. 89-95, 2003.
    • (2003) Archives of Biochemistry and Biophysics , vol.410 , Issue.1 , pp. 89-95
    • Cook, N.M.1    Shinyashiki, M.2    Jackson, M.I.3    Leal, F.A.4    Fukuto, J.M.5
  • 133
    • 0037399572 scopus 로고    scopus 로고
    • Angelis salt induces neurotoxicity in dopaminergic neurons in vivo and in vitro
    • A. J. Vaananen, M. Moed, R. K. Tuominen et al., Angelis salt induces neurotoxicity in dopaminergic neurons in vivo and in vitro, Free Radical Research, vol. 37, no. 4, pp. 381-389, 2003.
    • (2003) Free Radical Research , vol.37 , Issue.4 , pp. 381-389
    • Vaananen, A.J.1    Moed, M.2    Tuominen, R.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.