Mechanisms of inhibition of aldehyde dehydrogenase by nitroxyl, the active metabolite of the alcohol deterrent agent cyanamide

Biochemical Pharmacology

Volumn 55, Issue 12, 1998, Pages 2007-2015

  DeMaster, Eugene G ^a,c   Redfern, Beth ^a   Nagasawa, Herbert T ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c VA MEDICAL CENTER   (United States)

Author keywords

Aldehyde dehydrogenase inhibition; Angeli's salt; Cyanamide; Dithiothreitol; Glyceraldehyde 3 phosphate dehydrogenase inhibition; Nitric oxide; Nitroxyl

Indexed keywords

ALDEHYDE DEHYDROGENASE; BENZALDEHYDE; CYANAMIDE; DITHIOTHREITOL; DRUG METABOLITE; GLUTATHIONE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; NITRIC OXIDE; NITROXYL; REAGENT; SODIUM TRIOXODINITRATE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; DRUG ACTIVATION; DRUG MECHANISM; ENZYME INHIBITION; PRIORITY JOURNAL; YEAST;

ALCOHOLISM; ALDEHYDE DEHYDROGENASE; ANTIOXIDANTS; CYANAMIDE; HUMANS; NITRITES; NITROGEN OXIDES;

EID: 0032525919     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(98)00080-X     Document Type: Article

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