Farnesoid X receptor activation promotes cell proliferation via PDK4-controlled metabolic reprogramming

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Xie, Yang ^a,b   Wang, Hong ^a   Cheng, Xuefang ^a   Wu, Yuzheng ^a   Cao, Lijuan ^a   Wu, Mengqiu ^a   Xie, Wen ^b   Wang, Guangji ^a   Hao, Haiping ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 [2 [2 CHLORO 4 [3 (2,6 DICHLOROPHENYL) 5 ISOPROPYL 4 ISOXAZOLYLMETHOXY]PHENYL]VINYL]BENZOIC ACID; CELL RECEPTOR; FARNESOID X-ACTIVATED RECEPTOR; ISOXAZOLE DERIVATIVE; PROTEIN KINASE; PYRUVATE DEHYDROGENASE KINASE 4;

AGONISTS; ANIMAL; BIOLOGICAL MODEL; CELL PROLIFERATION; CLUSTER ANALYSIS; DISEASE MODEL; DRUG EFFECTS; ENERGY METABOLISM; GENETICS; GLYCOLYSIS; HEP-G2 CELL LINE; HUMAN; KNOCKOUT MOUSE; LIVER REGENERATION; METABOLISM; METABOLOME; METABOLOMICS; MOUSE; PATHOLOGY; PROCEDURES; TOXIC HEPATITIS; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; CHEMICAL AND DRUG INDUCED LIVER INJURY; CLUSTER ANALYSIS; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; GLYCOLYSIS; HEP G2 CELLS; HUMANS; ISOXAZOLES; LIVER REGENERATION; METABOLOME; METABOLOMICS; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; PROTEIN KINASES; RECEPTORS, CYTOPLASMIC AND NUCLEAR;

EID: 84953273695     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep18751     Document Type: Article

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