Antitumor Activity of Americanin A Isolated from the Seeds of Phytolacca americana by Regulating the ATM/ATR Signaling Pathway and the Skp2-p27 Axis in Human Colon Cancer Cells

Journal of Natural Products

Volumn 78, Issue 12, 2015, Pages 2983-2993

  Jung, Cholomi ^a   Hong, Ji Young ^a   Bae, Song Yi ^a   Kang, Sam Sik ^a   Park, Hyen Joo ^a   Lee, Sang Kook ^a  

^a Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMERICANIN A; ANTINEOPLASTIC AGENT; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CYCLIN DEPENDENT KINASE 1; DIOXIN; PROTEIN KINASE; PROTEIN P53;

ANIMAL; APOPTOSIS; CHEMICAL STRUCTURE; CHEMISTRY; COLON TUMOR; DRUG EFFECTS; G2 PHASE CELL CYCLE CHECKPOINT; HCT116 CELL LINE; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; MOUSE; NUDE MOUSE; PHYTOLACCA AMERICANA; PLANT SEED; SIGNAL TRANSDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CDC2 PROTEIN KINASE; CHECKPOINT KINASE 2; COLONIC NEOPLASMS; DIOXINS; G2 PHASE CELL CYCLE CHECKPOINTS; HCT116 CELLS; HUMANS; MICE; MICE, NUDE; MOLECULAR STRUCTURE; PHYTOLACCA AMERICANA; PROTEIN KINASES; SEEDS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84953265838     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/acs.jnatprod.5b00743     Document Type: Article

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