Nutrition and physical activity in nonalcoholic fatty liver disease

Journal of Diabetes Research

Volumn 2016, Issue , 2016, Pages

  Oliveira, Claudia P ^a   De Lima Sanches, Priscila ^b   De Abreu Silva, Erlon Oliveira ^b   Marcadenti, Aline ^c,d  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSIDADE FEDERAL DE CIÊNCIAS DA SAÚDE DE PORTO ALEGRE   (Brazil)

^d INSTITUTO DE CARDIOLOGIA DO RIO GRANDE DO SUL   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; CARBOHYDRATE; FAT; OMEGA 3 FATTY ACID; PHENOL DERIVATIVE; PREBIOTIC AGENT; PROBIOTIC AGENT; PROTEIN;

ALCOHOL CONSUMPTION; BRAZILIAN; COFFEE; DIET; EXERCISE; HUMAN; HYPERTENSION; MEDITERRANEAN DIET; NONALCOHOLIC FATTY LIVER; NONHUMAN; NUTRITION; PATHOPHYSIOLOGY; PHYSICAL ACTIVITY; PRACTICE GUIDELINE; PRESCRIPTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; RISK FACTOR; VITAMIN SUPPLEMENTATION; WEIGHT REDUCTION; INSULIN RESISTANCE; MOTOR ACTIVITY; NON-ALCOHOLIC FATTY LIVER DISEASE; NUTRITIONAL STATUS; PHYSIOLOGY;

DIET; EXERCISE; HUMANS; INSULIN RESISTANCE; MOTOR ACTIVITY; NON-ALCOHOLIC FATTY LIVER DISEASE; NUTRITIONAL STATUS;

EID: 84953217300     PISSN: 23146745     EISSN: 23146753     Source Type: Journal    
DOI: 10.1155/2016/4597246     Document Type: Review

References (92)

1. G. C. Farrell and C. Z. Larter, "Nonalcoholic fatty liver disease: from steatosis to cirrhosis," Hepatology, vol. 43, supplement 1, no. 2, pp. S99-S112, 2006.
2. M. Masarone, A. Federico, L. Abenavoli, C. Loguercio, and M. Persico, "Non alcoholic fatty liver: epidemiology and natural history," Reviews on Recent Clinical Trials, vol. 9, no. 3, pp. 126-133, 2014.
3. E. M. Brunt, C. G. Janney, A. M. Di Bisceglie, B. A. Neuschwander-Tetri, and B. R. Bacon, "Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions," American Journal of Gastroenterology, vol. 94, no. 9, pp. 2467-2474, 1999.
4. S. Bellentani, F. Scaglioni, M. Marino, and G. Bedogni, "Epidemiology of non-alcoholic fatty liver disease," Digestive Diseases, vol. 28, no. 1, pp. 155-161, 2010.
5. N. C. Leite, C. A. Villela-Nogueira, C. R. L. Cardoso, and G. F. Salles, "Non-alcoholic fatty liver disease and diabetes: from physiopathological interplay to diagnosis and treatment," World Journal of Gastroenterology, no. 26, pp. 8377-8392, 2014.
6. R. M. Williamson, J. F. Price, S. Glancy, et al., "Prevalence of and risk factors for hepatic steatosis and nonalcoholic fatty liver disease in people with type 2 diabetes: the Edinburgh type 2 diabetes study," Diabetes Care, vol. 34, no. 5, pp. 1139-1144, 2011.
7. K. Dvorak, R. Hainer, J. Petrtyl, et al., "The prevalence of nonalcoholic liver steatosis in patients with type 2 diabetes mellitus in the Czech Republic," Biomedical Papers, 2014.
8. P. Portillo Sanchez, F. Bril, M. Maximos, et al., "High prevalence of nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus and normal plasma aminotransferase levels," The Journal of Clinical Endocrinology & Metabolism, 2014.
9. M. Trauner, M. Arrese, and M. Wagner, "Fatty liver and lipotoxicity," Biochimica et Biophysica Acta, vol. 1801, no. 3, pp. 299-310, 2010.
10. F. Angelico, M. Del Ben, R. Conti, et al., "Insulin resistance, the metabolic syndrome, and nonalcoholic fatty liver disease," Journal of Clinical Endocrinology andMetabolism, vol. 90, no. 3, pp. 1578-1582, 2005.
11. W. I. Youssef and A. J. McCullough, "Steatohepatitis in obese individuals," Baillieres Best Practice and Research in Clinical Gastroenterology, vol. 16, no. 5, pp. 733-747, 2002.
12. C. P. Day and O. F. W. James, "Steatohepatitis: a tale of two hits?" Gastroenterology, vol. 114, no. 4, pp. 842-845, 1998.
13. A. E. Feldstein, "Novel insights into the pathophysiology of nonalcoholic fatty liver disease," Seminars in Liver Disease, vol. 30, no. 4, pp. 391-401, 2010.
14. S. Petta, C. Muratore, and A. Craxi, "Non-alcoholic fatty liver disease pathogenesis: the present and the future," Digestive and Liver Disease, vol. 41, no. 9, pp. 615-625, 2009.
15. C. A. Nagle, E. L. Klett, and R. A. Coleman, "Hepatic triacylglycerol accumulation and insulin resistance," Journal of Lipid Research, vol. 50, supplement, pp. S74-S79, 2009.
16. C. D. Byrne, R. Olufad, K. D. Bruce, F. R. Cagampang, and M. H. Ahmed, "Metabolic disturbances in non-alcoholic fatty liver disease," Clinical Science, vol. 116, no. 7, pp. 539-564, 2009.
17. M. Georgoulis, E. Fragopoulou, M. D. Kontogianni, et al., "Blood redox status is associated with the likelihood of nonalcoholic fatty liver disease irrespectively of diets total antioxidant capacity," Nutrition Research, vol. 35, no. 1, pp. 41-48, 2015.
18. E. Albano, E. Mottaran, M. Vidali, et al., "Immune response towards lipid peroxidation products as a predictor of progression of non-alcoholic fatty liver disease to advanced fibrosis," Gut, vol. 54, no. 7, pp. 987-993, 2005.
19. C. P. M. S. Oliveira, L. C. Da Costa Gayotto, C. Tatai, et al., "Oxidative stress in the pathogenesis of nonalcoholic fatty liver disease, in rats fed with a choline-deficient diet," Journal of Cellular and Molecular Medicine, vol. 6, no. 3, pp. 399-406, 2002.
20. E. Zamara, E. Novo, F. Marra, et al., "4-hydroxynonenal as a selective pro-fibrogenic stimulus for activated human hepatic stellate cells," Journal of Hepatology, vol. 40, no. 1, pp. 60-68, 2004.
21. A. Abdul-Hai, A. Abdallah, and S. D. H. Malnick, "Influence of gut bacteria on development and progression of non-alcoholic fatty liver disease," World Journal of Hepatology, vol. 7, no. 12, pp. 1679-1684, 2015.
22. K. O. Lytvynenko, P. M. Bodnar, T. O. Lysiana, I. H. Ponomarova, and O. A. Kovalchuk, "State of intestinal microbiota in patients with type 2 diabetesmellitus and non-alcoholic fatty liver disease," Likarska Spravas, no. 5-6, pp. 82-87, 2014.
23. X.-C. Jiang, Z. Li, R. Liu, et al., "Phospholipid transfer protein deficiency impairs apolipoprotein-B secretion from hepatocytes by stimulating a proteolytic pathway through a relative deficiency of vitamin E and an increase in intracellular oxidants," Journal of Biological Chemistry, vol. 280, no. 18, pp. 18336-18340, 2005.
24. L. Miele, V. Valenza, G. La Torre, et al., "Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease," Hepatology, vol. 49, no. 6, pp. 1877-1887, 2009.
25. L. Kikuchi, C. P. Oliveira, and F. J. Carrilho, "Nonalcoholic fatty liver disease and hepatocellular carcinoma," BioMed Research International, vol. 2014, Article ID 106247, 6 pages, 2014.
26. J.-W. Chai, Y.-C. Lin, J.-H. Chen, et al., "In vivo magnetic resonance (MR) study of fatty liver: importance of intracellular ultrastructural alteration for MR tissue parameters change," Journal of Magnetic Resonance Imaging, vol. 14, no. 1, pp. 35-41, 2001.
27. L. Castera, J. Vergniol, J. Foucher, et al., "Prospective comparison of transient elastography, fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C," Gastroenterology, vol. 128, no. 2, pp. 343-350, 2005.
28. B. E. Van Beers, R. Materne, L. Annet, et al., "Capillarization of the sinusoids in liver fibrosis: noninvasive assessment with contrast-enhanced MRI in the rabbit," Magnetic Resonance in Medicine, vol. 49, no. 4, pp. 692-699, 2003.
29. R. Kwok, K. C. Choi, G. L.-H. Wong, et al., "Screening diabetic patients for non-alcoholic fatty liver disease with controlled attenuation parameter and liver stiffness measurements: a prospective cohort study," Gut, 2015.
30. Q. Jia, Y. Xia, Q. Zhang, et al., "Dietary patterns are associated with prevalence of fatty liver disease in adults," European Journal of Clinical Nutrition, vol. 69, no. 8, pp. 914-921, 2015.
31. A. R. Moschen and H. Tilg, "Nutrition in pathophysiology and treatment of nonalcoholic fatty liver disease," Current Opinion in Clinical Nutrition and Metabolic Care, vol. 11, no. 5, pp. 620-625, 2008.
32. M. C. Elias, E. R. Parise, L. D. Carvalho, D. Szejnfeld, and J. P. Netto, "Effect of 6-month nutritional intervention on nonalcoholic fatty liver disease," Nutrition, vol. 26, no. 11-12, pp. 1094-1099, 2010.
33. K. Promrat, D. E. Kleiner, H. M. Niemeier, et al., "Randomized controlled trial testing the effects of weight loss on nonalcoholic steatohepatitis," Hepatology, vol. 51, no. 1, pp. 121-129, 2010.
34. N. Chalasani, Z. Younossi, J. E. Lavine, et al., "The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Association for the Study of Liver Diseases, AmericanCollege of Gastroenterology, and the American GastroenterologicalAssociation," Hepatology, vol. 55, no. 6, pp. 2005-2023, 2012.
35. R. C. Schugar and P. A. Crawford, "Low-carbohydrate ketogenic diets, glucose homeostasis, and nonalcoholic fatty liver disease," Current Opinion in Clinical Nutrition and Metabolic Care, vol. 15, no. 4, pp. 374-380, 2012.
36. T. Hu, K. T. Mills, L. Yao, et al., "Effectsof low-carbohydratediets versus low-fat diets on metabolic risk factors: a meta-analysis of randomized controlled clinical trials," American Journal of Epidemiology, vol. 176, no. supplement 7, pp. S44-S54, 2012.
37. A. M. Zivkovic, J. B. German, and A. J. Sanyal, "Comparative review of diets for the metabolic syndrome: implications for nonalcoholic fatty liver disease," The American Journal of Clinical Nutrition, vol. 86, no. 2, pp. 285-300, 2007.
38. M. Chung, J. Ma, K. Patel, S. Berger, J. Lau, and A. H. Lichtenstein, "Fructose, high-fructose corn syrup, sucrose, and nonalcoholic fatty liver disease or indexes of liver health: a systematic review and meta-analysis," American Journal of Clinical Nutrition, vol. 100, no. 3, pp. 833-849, 2014.
39. American Diabetes Association, "Nutrition recommendations and interventions for diabetes: a position statement of the American Diabetes Association," Diabetes Care, vol. 31, supplement 1, pp. S61-S78, 2007.
40. European Association for Cardiovascular Prevention & Rehabilitation, Z. Reiner, A. L. Catapano, et al., "ESC/EAS guidelines for the management of dyslipidaemias: the task force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS)," European Heart Journal, vol. 32, no. 14, pp. 1769-1818, 2011.
41. S. M. B. Duarte, J. Faintuch, J. T. Stefano, et al., "Hypocaloric high-protein diet improves clinical and biochemical markers in patients with Nonalcoholic Fatty Liver Disease (NAFLD)," Nutricion Hospitalaria, vol. 29, no. 1, pp. 94-101, 2014.
42. A. H. Kani, S. M. Alavian, A. Esmaillzadeh, P. Adibi, and L. Azadbakht, "Effects of a novel therapeutic diet on liver enzymes and coagulating factors in patientswith non-alcoholic fatty liver disease: a parallel randomized trial," Nutrition, vol. 30, no. 7-8, pp. 814-821, 2014.
43. A. Kargulewicz, H. Stankowiak-Kulpa, and M. Grzymislawski, "Dietary recommendations for patients with nonalcoholic fatty liver disease," Przeglad Gastroenterologiczny, vol. 9, no. 1, pp. 18-23, 2014.
44. P. Dongiovanni, C. Lanti, S. Gatti, et al., "High fat diet subverts hepatocellular iron uptake determining dysmetabolic iron overload," PLoS ONE, vol. 10, no. 2, Article IDe0116855, 2015.
45. J. Westerbacka, K. Lammi, A.-M. H?kkinen, et al., "Dietary fat content modifies liver fat in overweight nondiabetic subjects," Journal of Clinical Endocrinology andMetabolism, vol. 90, no. 5, pp. 2804-2809, 2005.
46. R. D. Santos, A. C. M. Gagliardi, H. T. Xavier, et al., "Sociedade Brasileira de Cardiologia. I Diretriz sobre o consumo de Gorduras e Sa?de Cardiovascular," Arquivos Brasileiros de Cardiologia, vol. 100, no. 1, supplement 3, pp. 1-40, 2013.
47. L. Bozzetto, A. Prinster, G. Annuzzi, et al., "Liver fat is reduced by an isoenergetic MUFA diet in a controlled randomized study in type 2 diabetic patients," Diabetes Care, vol. 35, no. 7, pp. 1429-1435, 2012.
48. M. Kruse, C. von Loeffelholz, D. Hoffmann, et al., "Dietary rapeseed/canola-oil supplementation reduces serum lipids and liver enzymes and alters postprandial inflammatory responses in adipose tissue compared to olive-oil supplementation in obese men," Molecular Nutrition & Food Research, vol. 59, no. 3, pp. 507-519, 2015.
49. R. Aller, D. A. deLuis, O. Izaola, B. de laFuente, and R. Bachiller, "Effect of a high monounsaturated vs high polyunsaturated fat hypocaloric diets in nonalcoholic fatty liver disease," European Review for Medical and Pharmacological Sciences, vol. 18, no. 7, pp. 1041-1047, 2014.
50. G. S. Masterton, J. N. Plevris, and P. C. Hayes, "Review article: omega-3 fatty acids-a promising novel therapy for non-alcoholic fatty liver disease," Alimentary Pharmacology and Therapeutics, vol. 31, no. 7, pp. 679-692, 2010.
51. M. Capanni, F. Calella, M. R. Biagini, et al., "Prolonged n-3 polyunsaturated fatty acid supplementation ameliorates hepatic steatosis in patientswith non-alcoholic fatty liver disease: a pilot study," Alimentary Pharmacology and Therapeutics, vol. 23, no. 8, pp. 1143-1151, 2006.
52. J. A. Parnell, M. Raman, K. P. Rioux, and R. A. Reimer, "The potential role of prebiotic fibre for treatment and management of non-alcoholic fatty liver disease and associated obesity and insulin resistance," Liver International, vol. 32, no. 5, pp. 701-711, 2012.
53. A. Iacono, G. M. Raso, R. B. Canani, A. Calignano, and R. Meli, "Probiotics as an emerging therapeutic strategy to treatNAFLD: focus on molecular and biochemical mechanisms," Journal of Nutritional Biochemistry, vol. 22, no. 8, pp. 699-711, 2011.
54. S. Nabavi, M. Rafraf, M. H. Somi, A. Homayouni-Rad, and M. Asghari-Jafarabadi, "Effects of probiotic yogurt consumption onmetabolic factors in individuals with nonalcoholic fatty liver disease," Journal of Dairy Science, vol. 97, no. 12, pp. 7386-7393, 2014.
55. Y.-Y. Ma, L. Li, C.-H. Yu, Z. Shen, L.-H. Chen, and Y.-M. Li, "Effects of probiotics onnonalcoholic fatty liver disease: a metaanalysis," World Journal of Gastroenterology, vol. 19, no. 40, pp. 6911-6918, 2013.
56. C. Buss, C. Valle-Tovo, S. Miozzo, and A. A. de Mattos, "Probiotics and synbiotics may improve liver aminotransferases levels in non-alcoholic fatty liver disease patients," Annals of Hepatology, vol. 13, no. 5, pp. 482-488, 2014.
57. N. Velasco, A. Contreras, and B. Grassi, "The mediterranean diet, hepatic steatosis and nonalcoholic fatty liver disease," Current Opinion in Clinical Nutrition & Metabolic Care, vol. 17, no. 5, pp. 453-457, 2014.
58. M. D. Kontogianni, N. Tileli, A. Margariti, et al., "Adherence to the Mediterranean diet is associated with the severity of nonalcoholic fatty liver disease," Clinical Nutrition, vol. 33, no. 4, pp. 678-683, 2014.
59. L. Abenavoli, "Non-alcoholic fatty liver disease and beneficial effects of dietary supplements,"World Journal ofHepatology, vol. 7, no. 12, pp. 1723-1724, 2015.
60. M. C. Ryan, C. Itsiopoulos, T. Thodis, et al., "The Mediterranean diet improves hepatic steatosis and insulin sensitivity in individuals with non-alcoholic fatty liver disease," Journal of Hepatology, vol. 59, no. 1, pp. 138-143, 2013.
61. A. Salehi-Abargouei, Z. Maghsoudi, F. Shirani, and L. Azadbakht, "Effects of Dietary Approaches to Stop Hypertension (DASH)-style diet on fatal or nonfatal cardiovascular diseases-Incidence: a systematic review and meta-analysis on observational prospective studies," Nutrition, vol. 29, no. 4, pp. 611-618, 2013.
62. F. Shirani, A. Salehi-Abargouei, and L. Azadbakht, "Effects of Dietary Approaches to Stop Hypertension (DASH) diet on some risk for developing type 2 diabetes: a systematic review and meta-analysis on controlled clinical trials," Nutrition, vol. 29, no. 7-8, pp. 939-947, 2013.
63. A. J. Sanyal, N. Chalasani, K. V. Kowdley, et al., "Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis,"The New England Journal of Medicine, vol. 362, no. 18, pp. 1675-1685, 2010.
64. H.-F. Ji, Y. Sun, and L. Shen, "Effect of vitamin E supplementation on aminotransferase levels in patients withNAFLD, NASH, and CHC: results from a meta-analysis," Nutrition, vol. 30, no. 9, pp. 986-991, 2014.
65. B. M. Attar and D. H. Van Thiel, "Current concepts and management approaches in nonalcoholic fatty liver disease," The Scientific World Journal, vol. 2013, Article ID 481893, 10 pages, 2013.
66. X. Jiang, D. Zhang, and W. Jiang, "Coffee and caffeine intake and incidence of type 2 diabetes mellitus: a meta-analysis of prospective studies," European Journal of Nutrition, vol. 53, no. 1, pp. 25-38, 2014.
67. L. Aguirre, M. P. Portillo, E. Hijona, and L. Bujanda, "Effects of resveratrol and other polyphenols in hepatic steatosis," World Journal of Gastroenterology, vol. 20, no. 23, pp. 7366-7380, 2014.
68. S. Chen, X. Zhao, L. Ran, et al., "Resveratrol improves insulin resistance, glucose and lipid metabolism in patients with nonalcoholic fatty liver disease: a randomized controlled trial," Digestive and Liver Disease, vol. 47, no. 13, pp. 226-232, 2015.
69. F. Faghihzadeh, P. Adibi, R. Rafiei, and A. Hekmatdoost, "Resveratrol supplementation improves inflammatory biomarkers in patients with nonalcoholic fatty liver disease," Nutrition Research, vol. 34, no. 10, pp. 837-843, 2014.
70. H. K. Seitz, S. Mueller, C. Hellerbrand, and S. Liangpunsakul, "Effect of chronic alcohol consumption on the development and progression of non-alcoholic fatty liver disease (NAFLD)," Hepatobiliary Surgery and Nutrition, vol. 4, no. 3, pp. 147-151, 2015.
71. T. Gunji, N. Matsuhashi, H. Sato, et al., "Light and moderate alcohol consumption significantly reduces the prevalence of fatty liver in the Japanese male population," The American Journal of Gastroenterology, vol. 104, no. 9, pp. 2189-2195, 2009.
72. A. Suzuki, P. Angulo, J. St. Sauver, A. Muto, T. Okada, and K. Lindor, "Light to moderate alcohol consumption is associated with lower frequency of hypertransaminasemia," American Journal of Gastroenterology, vol. 102, no. 9, pp. 1912-1919, 2007.
73. S. Sookoian, G. O. Castano, and C. J. Pirola, "Modest alcohol consumption decreases the risk of nonalcoholic fatty liver disease: a meta-analysis of 43 175 individuals," Gut, vol. 63, no. 3, pp. 530-532, 2014.
74. W. Dunn, A. J. Sanyal, E. M. Brunt, et al., "Modest alcohol consumption is associated with decreased prevalence of steatohepatitis in patients with non-alcoholic fatty liver disease (NAFLD)," Journal of Hepatology, vol. 57, no. 2, pp. 384-391, 2012.
75. V. Marti?-Domi?guez, R. Gonzlezs Casas, J. Mendoza-Jimnez-Ridruejo, L. Garci-Buey, and R. Moreno-Otero, "Pathogenesis, diagnosis and treatment of non-alcoholic fatty liver disease," Revista Espanola de Enfermedades Digestivas, vol. 105, no. 7, pp. 409-420, 2013.
76. I. J. Hickman, J. R. Jonsson, J. B. Prins, et al., "Modest weight loss and physical activity in overweight patients with chronic liver disease results in sustained improvements in alanine aminotransferase, fasting insulin, and quality of life," Gut, vol. 53, no. 3, pp. 413-419, 2004.
77. A. Suzuki, K. Lindor, J. S. Saver, et al., "Effect of changes on body weight and lifestyle in nonalcoholic fatty liver disease," Journal of Hepatology, vol. 43, no. 6, pp. 1060-1066, 2005.
78. N. A. Johnson and J. George, "Fitness versus fatness: moving beyond weight loss in nonalcoholic fatty liver disease," Hepatology, vol. 52, no. 1, pp. 370-381, 2010.
79. N. A. Johnson, T. Sachinwalla, D. W. Walton, et al., "Aerobic exercise training reduces hepatic and visceral lipids in obese individuals without weight loss," Hepatology, vol. 50, no. 4, pp. 1105-1112, 2009.
80. A. St. George, A. Bauman, A. Johnston, G. Farrell, T. Chey, and J. George, "Independent effects of physical activity in patients with nonalcoholic fatty liver disease," Hepatology, vol. 50, no. 1, pp. 68-76, 2009.
81. K. Hallsworth, G. Fattakhova, K. G. Hollingsworth, et al., "Resistance exercise reduces liver fat and its mediators in nonalcoholic fatty liver disease independent ofweight loss," Gut, vol. 60, no. 9, pp. 1278-1283, 2011.
82. C. A. Slentz, L. A. Bateman, L. H. Willis, et al., "Effects of aerobic vs. Resistance training on visceral and liver fat stores, liver enzymes, and insulin resistance byHOMAin overweight adults from STRRIDE AT/RT," American Journal of Physiology-Endocrinology andMetabolism, vol. 301, no. 5, pp. E1033-E1039, 2011.
83. J.-M. Lavoie and M.-S. Gauthier, "Regulation of fat metabolism in the liver: link to non-alcoholic hepatic steatosis and impact of physical exercise," Cellular and Molecular Life Sciences, vol. 63, no. 12, pp. 1393-1409, 2006.
84. R. Taylor, "Pathogenesis of type 2 diabetes: tracing the reverse route from cure to cause," Diabetologia, vol. 51, no. 10, pp. 1781-1789, 2008.
85. M. K. Holten, M. Zacho, M. Gaster, C. Juel, J. F. P. Wojtaszewski, and F. Dela, "Strength training increases insulin-mediated glucose uptake, GLUT4 content, and insulin signaling in skeletal muscle in patients with type 2 diabetes," Diabetes, vol. 53, no. 2, pp. 294-305, 2004.
86. J. J. Dub?, F. Amati, M. Stefanovic-Racic, F. G. S. Toledo, S. E. Sauers, and B. H. Goodpaster, "Exercise-induced alterations in intramyocellular lipids and insulin resistance: the athletes paradox revisited," The American Journal of Physiology-Endocrinology and Metabolism, vol. 294, no. 5, pp. E882-E888, 2008.
87. S. Schenk and J. F. Horowitz, "Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acidinduced insulin resistance,"The Journal of Clinical Investigation, vol. 117, no. 6, pp. 1690-1698, 2007.
88. C. Brandt and B. K. Pedersen, "The role of exercise-induced myokines in muscle homeostasis and the defense against chronic diseases," Journal of Biomedicine and Biotechnology, vol. 2010, Article ID 520258, 6 pages, 2010.
89. N. P. Walsh, M. Gleeson, R. J. Shephard, et al., "Position statement part one: immune function and exercise," Exercise Immunology Review, vol. 17, pp. 6-63, 2011.
90. S. Oh, K. Tanaka, E. Warabi, and J. Shoda, "Exercise reduces inflammation and oxidative stress in obesity-related liver diseases," Medicine & Science in Sports & Exercise, vol. 45, no. 12, pp. 2214-2222, 2013.
91. K. V. Kowdley, P. Belt, L. A. Wilson, et al., "Serum ferritin is an independent predictor of histologic severity and advanced fibrosis in patients with nonalcoholic fatty liver disease," Hepatology, vol. 55, no. 1, pp. 77-85, 2012.
92. C. Finelli and G. Tarantino, "Have guidelines addressing physical activity been established in nonalcoholic fatty liver disease?" World Journal of Gastroenterology, vol. 18, no. 46, pp. 6790-6800, 2012.