-
1
-
-
0035431018
-
Nonalcoholic fatty liver disease: A feature of the metabolic syndrome
-
PMID: 11473047
-
Marchesini G, Brizi M, Bianchi G, Tomassetti S, Bugianesi E, et al. (2001) Nonalcoholic fatty liver disease: a feature of the metabolic syndrome. Diabetes 50: 1844-1850. doi: 10.2337/diabetes.50.8.1844 PMID: 11473047
-
(2001)
Diabetes
, vol.50
, pp. 1844-1850
-
-
Marchesini, G.1
Brizi, M.2
Bianchi, G.3
Tomassetti, S.4
Bugianesi, E.5
-
2
-
-
43149120463
-
Donation frequency, iron loss, and risk of cancer among blood donors
-
PMID: 18398098
-
Edgren G, Reilly M, Hjalgrim H, Tran TN, Rostgaard K, et al. (2008) Donation frequency, iron loss, and risk of cancer among blood donors. J Natl Cancer Inst 100: 572-579. doi: 10.1093/jnci/djn084 PMID: 18398098
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 572-579
-
-
Edgren, G.1
Reilly, M.2
Hjalgrim, H.3
Tran, T.N.4
Rostgaard, K.5
-
3
-
-
2642608680
-
Serum ferritin as a component of the insulin resistance syndrome
-
PMID: 9580307
-
Fernandez-Real JM, Ricart-Engel W, Arroyo E, Balanca R, Casamitjana-Abella R, et al. (1998) Serum ferritin as a component of the insulin resistance syndrome. Diabetes Care 21: 62-68. doi: 10.2337/ diacare.21.1.62 PMID: 9580307
-
(1998)
Diabetes Care
, vol.21
, pp. 62-68
-
-
Fernandez-Real, J.M.1
Ricart-Engel, W.2
Arroyo, E.3
Balanca, R.4
Casamitjana-Abella, R.5
-
4
-
-
4644243396
-
Serum ferritin and risk of the metabolic syndrome in U.S. Adults
-
PMID: 15451911
-
Jehn M, Clark JM, Guallar E (2004) Serum ferritin and risk of the metabolic syndrome in U.S. adults. Diabetes Care 27: 2422-2428. doi: 10.2337/diacare.27.10.2422 PMID: 15451911
-
(2004)
Diabetes Care
, vol.27
, pp. 2422-2428
-
-
Jehn, M.1
Clark, J.M.2
Guallar, E.3
-
5
-
-
79251571756
-
Enhanced erythropoiesis in hfe-ko mice indicates a role for hfe in the modulation of erythroid iron homeostasis
-
PMID: 21059897
-
Ramos P, Guy E, Chen N, Proenca CC, Gardenghi S, et al. (2011) Enhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis. Blood 117: 1379-1389. doi: 10.1182/blood-2010-09-307462 PMID: 21059897
-
(2011)
Blood
, vol.117
, pp. 1379-1389
-
-
Ramos, P.1
Guy, E.2
Chen, N.3
Proenca, C.C.4
Gardenghi, S.5
-
6
-
-
80052940689
-
Iron in fatty liver and in the metabolic syndrome: A promising therapeutic target
-
PMID: 21718726
-
Dongiovanni P, Fracanzani AL, Fargion S, Valenti L (2011) Iron in fatty liver and in the metabolic syndrome: A promising therapeutic target. J Hepatol 55: 920-932. doi: 10.1016/j.jhep.2011.05.008 PMID: 21718726
-
(2011)
J Hepatol
, vol.55
, pp. 920-932
-
-
Dongiovanni, P.1
Fracanzani, A.L.2
Fargion, S.3
Valenti, L.4
-
7
-
-
55449134689
-
Revaluation of clinical and histological criteria for diagnosis of dysmetabolic iron overload syndrome
-
PMID: 18720534
-
Riva A, Trombini P, Mariani R, Salvioni A, Coletti S, et al. (2008) Revaluation of clinical and histological criteria for diagnosis of dysmetabolic iron overload syndrome. World J Gastroenterol 14: 4745-4752. doi: 10.3748/wjg.14.4745 PMID: 18720534
-
(2008)
World J Gastroenterol
, vol.14
, pp. 4745-4752
-
-
Riva, A.1
Trombini, P.2
Mariani, R.3
Salvioni, A.4
Coletti, S.5
-
8
-
-
80052960022
-
Dietary iron overload induces visceral adipose tissue insulin resistance associated with hyper-resistinemia, and synergizes with obesity and fatty liver in inducing systemic insulin resistance
-
Dongiovanni P, Ruscica M, Benedan L, Borroni V, Recalcati S, et al. (2011) Dietary iron overload induces visceral adipose tissue insulin resistance associated with hyper-resistinemia, and synergizes with obesity and fatty liver in inducing systemic insulin resistance. J Hepatol 54: S505.
-
(2011)
J Hepatol
, vol.54
, pp. S505
-
-
Dongiovanni, P.1
Ruscica, M.2
Benedan, L.3
Borroni, V.4
Recalcati, S.5
-
9
-
-
84867167258
-
Adipocyte iron regulates adiponectin and insulin sensitivity
-
PMID: 22996660
-
Gabrielsen JS, Gao Y, Simcox JA, Huang J, Thorup D, et al. (2012) Adipocyte iron regulates adiponectin and insulin sensitivity. J Clin Invest 122: 3529-3540. doi: 10.1172/JCI44421 PMID: 22996660
-
(2012)
J Clin Invest
, vol.122
, pp. 3529-3540
-
-
Gabrielsen, J.S.1
Gao, Y.2
Simcox, J.A.3
Huang, J.4
Thorup, D.5
-
10
-
-
84878225591
-
Iron metabolism is associated with adipocyte insulin resistance and plasma adiponectin
-
ePub ahead of print
-
Wlazlo N, van Greevenbroek MMJ, Ferreira I, Jansen EHJM, Feskens EJ, et al. (2012) Iron Metabolism Is Associated With Adipocyte Insulin Resistance and Plasma Adiponectin. Diabetes Care: ePub ahead of print.
-
(2012)
Diabetes Care
-
-
Wlazlo, N.1
Van Greevenbroek, M.M.J.2
Ferreira, I.3
Jansen, E.H.J.M.4
Feskens, E.J.5
-
11
-
-
0036211032
-
Effect of iron depletion in carbohydrate-intolerant patients with clinical evidence of nonalcoholic fatty liver disease
-
PMID: 11910345
-
Facchini FS, Hua NW, Stoohs RA (2002) Effect of iron depletion in carbohydrate-intolerant patients with clinical evidence of nonalcoholic fatty liver disease. Gastroenterology 122: 931-939. doi: 10.1053/ gast.2002.32403 PMID: 11910345
-
(2002)
Gastroenterology
, vol.122
, pp. 931-939
-
-
Facchini, F.S.1
Hua, N.W.2
Stoohs, R.A.3
-
12
-
-
34249098685
-
Iron depletion by phlebotomy improves insulin resistance in patients with nonalcoholic fatty liver disease and hyperferritinemia: Evidence from a case-control study
-
PMID: 17391316
-
Valenti L, Fracanzani AL, Dongiovanni P, Bugianesi E, Marchesini G, et al. (2007) Iron depletion by phlebotomy improves insulin resistance in patients with nonalcoholic fatty liver disease and hyperferritinemia: evidence from a case-control study. Am J Gastroenterol 102: 1251-1258. doi: 10.1111/j.1572- 0241.2007.01192.x PMID: 17391316
-
(2007)
Am J Gastroenterol
, vol.102
, pp. 1251-1258
-
-
Valenti, L.1
Fracanzani, A.L.2
Dongiovanni, P.3
Bugianesi, E.4
Marchesini, G.5
-
13
-
-
0034891077
-
Hyperferritinemia, iron overload, and multiple metabolic alterations identify patients at risk for nonalcoholic steatohepatitis
-
PMID: 11513189
-
Fargion S, Mattioli M, Fracanzani AL, Sampietro M, Tavazzi D, et al. (2001) Hyperferritinemia, iron overload, and multiple metabolic alterations identify patients at risk for nonalcoholic steatohepatitis. Am J Gastroenterol 96: 2448-2455. doi: 10.1111/j.1572-0241.2001.04052.x PMID: 11513189
-
(2001)
Am J Gastroenterol
, vol.96
, pp. 2448-2455
-
-
Fargion, S.1
Mattioli, M.2
Fracanzani, A.L.3
Sampietro, M.4
Tavazzi, D.5
-
14
-
-
77249139227
-
HFE genotype, parenchymal iron accumulation, and liver fibrosis in patients with nonalcoholic fatty liver disease
-
PMID: 19931264
-
Valenti L, Fracanzani A, Bugianesi E, Dongiovanni P, Galmozzi E, et al. (2010) HFE genotype, parenchymal iron accumulation, and liver fibrosis in patients with nonalcoholic fatty liver disease. Gastroenterology 138: 905-912. doi: 10.1053/j.gastro.2009.11.013 PMID: 19931264
-
(2010)
Gastroenterology
, vol.138
, pp. 905-912
-
-
Valenti, L.1
Fracanzani, A.2
Bugianesi, E.3
Dongiovanni, P.4
Galmozzi, E.5
-
15
-
-
84155188801
-
Serum ferritin is an independent predictor of histologic severity and advanced fibrosis in patients with nonalcoholic fatty liver disease
-
PMID: 21953442
-
Kowdley KV, Belt P, Wilson LA, Yeh MM, Neuschwander-Tetri BA, et al. (2012) Serum ferritin is an independent predictor of histologic severity and advanced fibrosis in patients with nonalcoholic fatty liver disease. Hepatology 55: 77-85. doi: 10.1002/hep.24706 PMID: 21953442
-
(2012)
Hepatology
, vol.55
, pp. 77-85
-
-
Kowdley, K.V.1
Belt, P.2
Wilson, L.A.3
Yeh, M.M.4
Neuschwander-Tetri, B.A.5
-
16
-
-
77957376214
-
Beta-globin mutations are associated with parenchymal siderosis and fibrosis in patients with non-alcoholic fatty liver disease
-
PMID: 20739079
-
Valenti L, Canavesi E, Galmozzi E, Dongiovanni P, Rametta R, et al. (2010) Beta-globin mutations are associated with parenchymal siderosis and fibrosis in patients with non-alcoholic fatty liver disease. J Hepatol 53: 927-933. doi: 10.1016/j.jhep.2010.05.023 PMID: 20739079
-
(2010)
J Hepatol
, vol.53
, pp. 927-933
-
-
Valenti, L.1
Canavesi, E.2
Galmozzi, E.3
Dongiovanni, P.4
Rametta, R.5
-
17
-
-
78149358654
-
Serum ferritin levels are associated with vascular damage in patients with nonalcoholic fatty liver disease
-
in press
-
Valenti L, Swinkels DW, Burdick L, Dongiovanni P, Tjalsma H, et al. (2010) Serum ferritin levels are associated with vascular damage in patients with nonalcoholic fatty liver disease. Nutr Metab Cardiovasc: in press.
-
(2010)
Nutr Metab Cardiovasc
-
-
Valenti, L.1
Swinkels, D.W.2
Burdick, L.3
Dongiovanni, P.4
Tjalsma, H.5
-
18
-
-
79952191602
-
Serum hepcidin and macrophage iron correlate with mcp-1 release and vascular damage in patients with metabolic syndrome alterations
-
PMID: 21183736
-
Valenti L, Dongiovanni P, Motta BM, Swinkels DW, Bonara P, et al. (2011) Serum Hepcidin and Macrophage Iron Correlate With MCP-1 Release and Vascular Damage in Patients With Metabolic Syndrome Alterations. Arterioscler Thromb Vasc Biol 31: 683-690. doi: 10.1161/ATVBAHA.110.214858 PMID: 21183736
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 683-690
-
-
Valenti, L.1
Dongiovanni, P.2
Motta, B.M.3
Swinkels, D.W.4
Bonara, P.5
-
19
-
-
84868095049
-
Serum hepcidin levels in subjects with the metabolic syndrome. A population study
-
PMID: 23144745
-
Martinelli N, Traglia M, Campostrini N, Biino G, Corbella M, et al. (2012) Serum hepcidin levels in subjects with the metabolic syndrome. A population study. PLOS ONE 7: e48250. doi: 10.1371/journal. pone.0048250 PMID: 23144745
-
(2012)
PLOS ONE
, vol.7
-
-
Martinelli, N.1
Traglia, M.2
Campostrini, N.3
Biino, G.4
Corbella, M.5
-
20
-
-
48549094554
-
Copper availability contributes to iron perturbations in human nonalcoholic fatty liver disease
-
PMID: 18505688
-
Aigner E, Theurl I, Haufe H, Seifert M, Hohla F, et al. (2008) Copper availability contributes to iron perturbations in human nonalcoholic fatty liver disease. Gastroenterology 135: 680-688. doi: 10.1053/j. gastro.2008.04.007 PMID: 18505688
-
(2008)
Gastroenterology
, vol.135
, pp. 680-688
-
-
Aigner, E.1
Theurl, I.2
Haufe, H.3
Seifert, M.4
Hohla, F.5
-
21
-
-
44649155598
-
Hepcidin and iron-related gene expression in subjects with dysmetabolic hepatic iron overload
-
PMID: 18462824
-
Barisani D, Pelucchi S, Mariani R, Galimberti S, Trombini P, et al. (2008) Hepcidin and iron-related gene expression in subjects with Dysmetabolic Hepatic Iron Overload. J Hepatol 49: 123-133. doi: 10. 1016/j.jhep.2008.03.011 PMID: 18462824
-
(2008)
J Hepatol
, vol.49
, pp. 123-133
-
-
Barisani, D.1
Pelucchi, S.2
Mariani, R.3
Galimberti, S.4
Trombini, P.5
-
22
-
-
43549087627
-
Pathways underlying iron accumulation in human nonalcoholic fatty liver disease
-
PMID: 18469261
-
Aigner E, Theurl I, Theurl M, Lederer D, Haufe H, et al. (2008) Pathways underlying iron accumulation in human nonalcoholic fatty liver disease. Am J Clin Nutr 87: 1374-1383. PMID: 18469261
-
(2008)
Am J Clin Nutr
, vol.87
, pp. 1374-1383
-
-
Aigner, E.1
Theurl, I.2
Theurl, M.3
Lederer, D.4
Haufe, H.5
-
23
-
-
84868349912
-
The a736v tmprss6 polymorphism influences hepatic iron overload in nonalcoholic fatty liver disease
-
PMID: 23144979
-
Valenti L, Rametta R, Dongiovanni P, Motta BM, Canavesi E, et al. (2012) The A736V TMPRSS6 Polymorphism Influences Hepatic Iron Overload in Nonalcoholic Fatty Liver Disease. PLoS One 7: e48804. doi: 10.1371/journal.pone.0048804 PMID: 23144979
-
(2012)
PLoS One
, vol.7
-
-
Valenti, L.1
Rametta, R.2
Dongiovanni, P.3
Motta, B.M.4
Canavesi, E.5
-
24
-
-
33748794808
-
A model of insulin resistance and nonalcoholic steatohepatitis in rats: Role of peroxisome proliferator-activated receptor- alpha and n-3 polyunsaturated fatty acid treatment on liver injury
-
PMID: 16936261
-
Svegliati-Baroni G, Candelaresi C, Saccomanno S, Ferretti G, Bachetti T, et al. (2006) A model of insulin resistance and nonalcoholic steatohepatitis in rats: role of peroxisome proliferator-activated receptor- alpha and n-3 polyunsaturated fatty acid treatment on liver injury. Am J Pathol 169: 846-860. doi: 10.2353/ajpath.2006.050953 PMID: 16936261
-
(2006)
Am J Pathol
, vol.169
, pp. 846-860
-
-
Svegliati-Baroni, G.1
Candelaresi, C.2
Saccomanno, S.3
Ferretti, G.4
Bachetti, T.5
-
25
-
-
0015228412
-
Measurement of liver iron concentration in needle biopsy specimens
-
PMID: 4099600
-
Barry M, Sherlock S (1971) Measurement of liver iron concentration in needle biopsy specimens. Lancet 1: 100-103. doi: 10.1016/S0140-6736(71)90838-5 PMID: 4099600
-
(1971)
Lancet
, vol.1
, pp. 100-103
-
-
Barry, M.1
Sherlock, S.2
-
26
-
-
0028928738
-
Induction of ferritin synthesis by oxidative stress. Transcriptional and post-transcriptional regulation by expansion of the "free" iron pool
-
PMID: 7822298
-
Cairo G, Tacchini L, Pogliaghi G, Anzon E, Tomasi A, et al. (1995) Induction of ferritin synthesis by oxidative stress. Transcriptional and post-transcriptional regulation by expansion of the "free" iron pool. J Biol Chem 270: 700-703. doi: 10.1074/jbc.270.2.700 PMID: 7822298
-
(1995)
J Biol Chem
, vol.270
, pp. 700-703
-
-
Cairo, G.1
Tacchini, L.2
Pogliaghi, G.3
Anzon, E.4
Tomasi, A.5
-
27
-
-
76149107519
-
Iron dependent regulation of mdm2 influences p53 activity and hepatic carcinogenesis
-
in press., PMID: 20019189
-
Dongiovanni P, Fracanzani A, Cairo G, Megazzini CP, Gatti S, et al. (2010) Iron dependent regulation of MDM2 influences p53 activity and hepatic carcinogenesis. Am J Pathol 176: in press. doi: 10.2353/ ajpath.2010.090249 PMID: 20019189
-
(2010)
Am J Pathol
, vol.176
-
-
Dongiovanni, P.1
Fracanzani, A.2
Cairo, G.3
Megazzini, C.P.4
Gatti, S.5
-
28
-
-
20044374023
-
Design and validation of a histological scoring system for nonalcoholic fatty liver disease
-
PMID: 15915461
-
Kleiner DE, Brunt EM, Van Natta M, Behling C, Contos MJ, et al. (2005) Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 41: 1313-1321. doi: 10.1002/ hep.20701 PMID: 15915461
-
(2005)
Hepatology
, vol.41
, pp. 1313-1321
-
-
Kleiner, D.E.1
Brunt, E.M.2
Van Natta, M.3
Behling, C.4
Contos, M.J.5
-
29
-
-
39149136945
-
Hepatic pathology in relatives of patients with hemochromatosis
-
PMID: 14498313
-
Scheuer PG, Williams R, Muir AR (1962) Hepatic pathology in relatives of patients with hemochromatosis. J Pathol Bacteriol 84: 53-64. doi: 10.1002/path.1700840107 PMID: 14498313
-
(1962)
J Pathol Bacteriol
, vol.84
, pp. 53-64
-
-
Scheuer, P.G.1
Williams, R.2
Muir, A.R.3
-
30
-
-
11144289986
-
Iron metabolism and toxicity
-
PMID: 15629195
-
Papanikolaou G, Pantopoulos K (2005) Iron metabolism and toxicity. Toxicol Appl Pharmacol 202: 199-211. doi: 10.1016/j.taap.2004.06.021 PMID: 15629195
-
(2005)
Toxicol Appl Pharmacol
, vol.202
, pp. 199-211
-
-
Papanikolaou, G.1
Pantopoulos, K.2
-
31
-
-
79959517565
-
Human fatty liver disease: Old questions and new insights
-
PMID: 21700865
-
Cohen JC, Horton JD, Hobbs HH (2011) Human fatty liver disease: old questions and new insights. Science 332: 1519-1523. doi: 10.1126/science.1204265 PMID: 21700865
-
(2011)
Science
, vol.332
, pp. 1519-1523
-
-
Cohen, J.C.1
Horton, J.D.2
Hobbs, H.H.3
-
32
-
-
79960479283
-
Molecular mechanisms regulating hepcidin revealed by hepcidin disorders
-
PMID: 21789471
-
Camaschella C, Silvestri L (2011) Molecular mechanisms regulating hepcidin revealed by hepcidin disorders. ScientificWorldJournal 11: 1357-1366. doi: 10.1100/tsw.2011.130 PMID: 21789471
-
(2011)
ScientificWorldJournal
, vol.11
, pp. 1357-1366
-
-
Camaschella, C.1
Silvestri, L.2
-
33
-
-
84866007988
-
Macrophages and systemic iron homeostasis
-
PMID: 22441209
-
Ganz T (2012) Macrophages and systemic iron homeostasis. J Innate Immun 4: 446-453. doi: 10. 1159/000336423 PMID: 22441209
-
(2012)
J Innate Immun
, vol.4
, pp. 446-453
-
-
Ganz, T.1
-
34
-
-
32044456491
-
Iron accumulation in alcoholic liver diseases
-
PMID: 16344607
-
Kohgo Y, Ohtake T, Ikuta K, Suzuki Y, Hosoki Y, et al. (2005) Iron accumulation in alcoholic liver diseases. Alcohol Clin Exp Res 29: 189S-193S. doi: 10.1097/01.alc.0000189274.00479.62 PMID: 16344607
-
(2005)
Alcohol Clin Exp Res
, vol.29
, pp. 189S-193S
-
-
Kohgo, Y.1
Ohtake, T.2
Ikuta, K.3
Suzuki, Y.4
Hosoki, Y.5
-
35
-
-
0034531651
-
Iron regulatory proteins in pathobiology
-
PMID: 11085915
-
Cairo G, Pietrangelo A (2000) Iron regulatory proteins in pathobiology. Biochem J 352 Pt 2: 241-250. doi: 10.1042/0264-6021:3520241 PMID: 11085915
-
(2000)
Biochem J
, vol.352
, pp. 241-250
-
-
Cairo, G.1
Pietrangelo, A.2
-
36
-
-
84879263200
-
High fat diet induces liver steatosis and early dysregulation of iron metabolism in rats
-
PMID: 23805238
-
Meli R, Mattace Raso G, Irace C, Simeoli R, Di Pascale A, et al. (2013) High Fat Diet Induces Liver Steatosis and Early Dysregulation of Iron Metabolism in Rats. PLoS One 8: e66570. PMID: 23805238
-
(2013)
PLoS One
, vol.8
-
-
Meli, R.1
Mattace Raso, G.2
Irace, C.3
Simeoli, R.4
Di Pascale, A.5
-
37
-
-
84873522131
-
Dietary fat level affects tissue iron levels but not the iron regulatory gene hamp in rats
-
PMID: 23399663
-
Ahmed U, Oates PS (2013) Dietary fat level affects tissue iron levels but not the iron regulatory gene HAMP in rats. Nutr Res 33: 126-135. doi: 10.1016/j.nutres.2012.11.012 PMID: 23399663
-
(2013)
Nutr Res
, vol.33
, pp. 126-135
-
-
Ahmed, U.1
Oates, P.S.2
-
38
-
-
84869088411
-
High-fat diet causes iron deficiency via hepcidin-independent reduction of duodenal iron absorption
-
PMID: 22444869
-
Sonnweber T, Ress C, Nairz M, Theurl I, Schroll A, et al. (2012) High-fat diet causes iron deficiency via hepcidin-independent reduction of duodenal iron absorption. J Nutr Biochem 23: 1600-1608. doi: 10. 1016/j.jnutbio.2011.10.013 PMID: 22444869
-
(2012)
J Nutr Biochem
, vol.23
, pp. 1600-1608
-
-
Sonnweber, T.1
Ress, C.2
Nairz, M.3
Theurl, I.4
Schroll, A.5
-
39
-
-
20044366342
-
Kupffer cells and macrophages are not required for hepatic hepcidin activation during iron overload
-
PMID: 15726660
-
Montosi G, Corradini E, Garuti C, Barelli S, Recalcati S, et al. (2005) Kupffer cells and macrophages are not required for hepatic hepcidin activation during iron overload. Hepatology 41: 545-552. doi: 10. 1002/hep.20620 PMID: 15726660
-
(2005)
Hepatology
, vol.41
, pp. 545-552
-
-
Montosi, G.1
Corradini, E.2
Garuti, C.3
Barelli, S.4
Recalcati, S.5
-
40
-
-
84861788364
-
Ferritin couples iron and fatty acid metabolism
-
PMID: 22362897
-
Bu W, Liu R, Cheung-Lau JC, Dmochowski IJ, Loll PJ, et al. (2012) Ferritin couples iron and fatty acid metabolism. FASEB J 26: 2394-2400. doi: 10.1096/fj.11-198853 PMID: 22362897
-
(2012)
FASEB J
, vol.26
, pp. 2394-2400
-
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Bu, W.1
Liu, R.2
Cheung-Lau, J.C.3
Dmochowski, I.J.4
Loll, P.J.5
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