Anti-proliferative activity and chemical characterization by comprehensive two-dimensional liquid chromatography coupled to mass spectrometry of phlorotannins from the brown macroalga Sargassum muticum collected on North-Atlantic coasts

Journal of Chromatography A

Volumn 1428, Issue , 2016, Pages 115-125

  Montero, Lidia ^a   Sánchez Camargo, Andrea P ^a   García Cañas, Virginia ^a   Tanniou, Anaëlle ^b   Stiger Pouvreau, Valérie ^b   Russo, Mariateresa ^c   Rastrelli, Luca ^d   Cifuentes, Alejandro ^a   Herrero, Miguel ^a   Ibáñez, Elena ^a  

^a INSTITUTE OF FOOD SCIENCE RESEARCH CIAL   (Spain)

^b UNIVERSITÉ DE BRETAGNE OCCIDENTALE   (France)

^c UNIVERSITY MEDITERRANEA OF REGGIO CALABRIA   (Italy)

^d UNIVERSITY OF SALERNO   (Italy)

Author keywords

Anti proliferative activity; Brown algae; Comprehensive LC; Phenolic compounds; Phlorotannins; Sargassum muticum

Indexed keywords

ALGAE; CHROMATOGRAPHY; CYTOTOXICITY; LOCATION; MASS SPECTROMETRY; PHENOLS;

ANTI-PROLIFERATIVE ACTIVITIES; BROWN ALGAE; COMPREHENSIVE LC; PHENOLIC COMPOUNDS; PHLOROTANNINS; SARGASSUM MUTICUM;

LIQUID CHROMATOGRAPHY;

ALGAL EXTRACT; ANTINEOPLASTIC AGENT; DIHYDROXYHEPTAFUHALOL; DIHYDROXYHEXAFUHALOL; DIHYDROXYPENTAFUHALOL; DIHYDROXYTETRAFUHALOL; FUHALOL DERIVATIVE; HEPTAPHLORETHOL; HEXAFUHALOL; HEXAPHLORETHOL; HYDROXYFUHALOL DERIVATIVE; HYDROXYHEPTAFUHALOL; HYDROXYHEXAFUHALOL; HYDROXYPENTAFUHALOL; HYDROXYTETRAFUHALOL; NONAFUHALOL; OCTAFUHALOL; PENTAFUHALOL; PENTAPHLORETHOL; PHENOL DERIVATIVE; PHLORETHOL DERIVATIVE; PHLOROGLUCINOL; PHLOROTANNIN DERIVATIVE; SARGASSUM MUTICUM EXTRACT; TANNIN DERIVATIVE; TETRAFUHALOL; TRIFUHALOL; TRIHYDROXYHEPTAFUHALOL; TRIHYDROXYHEXAFUHALOL; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BIOCHEMICAL COMPOSITION; BIOLOGICAL ACTIVITY; CHROMATOGRAPH; COASTAL WATERS; COLON ADENOCARCINOMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG PURIFICATION; DRUG SCREENING; DRUG STRUCTURE; HT 29 CELL LINE; HUMAN; HUMAN CELL; HYDROPHILIC INTERACTION CHROMATOGRAPHY; ION TRAP MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETER; NONHUMAN; NORWAY; POLYMERIZATION; PORTUGAL; PRIORITY JOURNAL; SARGASSUM; SARGASSUM MUTICUM; SEPARATION TECHNIQUE; ATLANTIC OCEAN; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; ISOLATION AND PURIFICATION; TANDEM MASS SPECTROMETRY;

ANTINEOPLASTIC AGENTS; ATLANTIC OCEAN; CELL PROLIFERATION; CHROMATOGRAPHY, LIQUID; HT29 CELLS; HUMANS; PHENOLS; PHLOROGLUCINOL; SARGASSUM; TANDEM MASS SPECTROMETRY; TANNINS;

EID: 84952982803     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2015.07.053     Document Type: Article

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