Glycyrrhetinic acid induces cytoprotective autophagy via the inositol-requiring enzyme 1α-c-Jun N-terminal kinase cascade in non-small cell lung cancer cells

Oncotarget

Volumn 6, Issue 41, 2015, Pages 43911-43926

  Tang, Zheng Hai ^a   Zhang, Le Le ^a   Li, Ting ^a   Lu, Jia Hong ^a   Ma, Dik Lung ^b   Leung, Chung Hang ^a   Chen, Xiu Ping ^a   Jiang, Hu Lin ^c   Wang, Yi Tao ^a   Lu, Jin Jian ^a  

^a University of Macau   (Macao)

^b HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^c CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Autophagy; Glycyrrhetinic acid; IRE1 ; JNK; Protective

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; GLYCYRRHETINIC ACID; GREEN FLUORESCENT PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; PHOSPHATIDYLETHANOLAMINE; PROTEIN IRE1; PROTEIN IRE1ALPHA; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; ERN1 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; RIBONUCLEASE;

A549 CELL LINE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER INHIBITION; CELL PROTECTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; GENE SILENCING; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; IRE1ALPHA GENE; LIGHT CHAIN; LUNG CANCER CELL LINE; NCI H1299 CELL LINE; NON SMALL CELL LUNG CANCER; ONCOGENE C JUN; PROTEIN EXPRESSION; CELL PROLIFERATION; CELL SURVIVAL; DRUG EFFECTS; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC TRANSFECTION; LUNG TUMOR; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; AUTOPHAGY; BLOTTING, WESTERN; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; ENDORIBONUCLEASES; FLUORESCENT ANTIBODY TECHNIQUE; GLYCYRRHETINIC ACID; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LUNG NEOPLASMS; MAP KINASE SIGNALING SYSTEM; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84952923768     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.6084     Document Type: Article

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