The chemotherapeutic agent paclitaxel inhibits autophagy through two distinct mechanisms that regulate apoptosis

Oncogene

Volumn 32, Issue 6, 2013, Pages 736-746

  Veldhoen, R A ^a   Banman, S L ^a   Hemmerling, D R ^b   Odsen, R ^a   Simmen, T ^a   Simmonds, A J ^a   Underhill, D A ^a   Goping, I S ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b Department of Philosophy and Religious Studies   (Canada)

Author keywords

apoptosis; autophagy; paclitaxel

Indexed keywords

BAFILOMYCIN; PACLITAXEL; PHOSPHATIDYLINOSITOL 3 KINASE;

APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BREAST CANCER; CANCER CELL; CELL ADHESION; CELL CYCLE ARREST; CELL CYCLE REGULATION; CELL STRAIN MCF 7; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; HUMAN; HUMAN CELL; MITOSIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; AUTOPHAGY; BREAST NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; CLASS III PHOSPHATIDYLINOSITOL 3-KINASES; FEMALE; HUMANS; PACLITAXEL;

EID: 84873708956     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.92     Document Type: Article

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