Undefined role of mucus as a barrier in ocular drug delivery

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 96, Issue , 2015, Pages 442-446

  Ruponen, Marika ^a   Urtti, Arto ^a,b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Conjunctival permeation; Corneal permeation; Mucin; Mucoadhesion; Mucus; Nanoparticle; Ocular drug delivery

Indexed keywords

MUCIN; DRUG CARRIER; NANOPARTICLE;

CHEMICAL COMPOSITION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; HUMAN; INTRAOCULAR DRUG ADMINISTRATION; MUCUS; PROTEIN FUNCTION; REVIEW; SURFACE PROPERTY; ABSORPTION; ANIMAL; BLOOD EYE BARRIER; BLOOD RETINA BARRIER; CHEMISTRY; CONJUNCTIVA; CORNEA; EYE; GLYCOCALYX; LACRIMAL APPARATUS; METABOLISM; MUCOSA; PERMEABILITY; PHARMACOKINETICS; SECRETION (PROCESS); TISSUE DISTRIBUTION;

ABSORPTION, PHYSIOLOGICAL; ADMINISTRATION, OPHTHALMIC; ANIMALS; BLOOD-AQUEOUS BARRIER; BLOOD-RETINAL BARRIER; CONJUNCTIVA; CORNEA; DRUG CARRIERS; EYE; GLYCOCALYX; HUMANS; LACRIMAL APPARATUS; MUCINS; MUCOUS MEMBRANE; MUCUS; NANOPARTICLES; PERMEABILITY; PHARMACOKINETICS; TISSUE DISTRIBUTION;

EID: 84952877397     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2015.02.032     Document Type: Review

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