A metalloproteinase secreted by Streptococcus pneumoniae removes membrane mucin MUC16 from the epithelial glycocalyx barrier

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Govindarajan, Bharathi ^a   Menon, Balaraj B ^a   Spurr Michaud, Sandra ^a   Rastogi, Komal ^a   Gilmore, Michael S ^a   Argüeso, Pablo ^a   Gipson, Ilene K ^a  

^a SCHEPENS EYE RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN; METALLOPROTEINASE; MUCIN 1; MUCIN 16; MUCIN 4; PROTEIN ZMPC; UNCLASSIFIED DRUG; CA 125 ANTIGEN; MEMBRANE PROTEIN; MUC16 PROTEIN, HUMAN; ZMPC PROTEIN, STREPTOCOCCUS PNEUMONIAE;

ARTICLE; BACTERIAL STRAIN; BRONCHUS MUCOSA; CELL DIFFERENTIATION; CONJUNCTIVA EPITHELIUM; CONTROLLED STUDY; CORNEA EPITHELIUM; ENZYME RELEASE; EPITHELIUM CELL; GLYCOCALYX; HUMAN; HUMAN CELL; INTERNALIZATION; NONHUMAN; PROTEIN EXPRESSION; STREPTOCOCCUS PNEUMONIA; CELL CULTURE; CELL LINE; ENZYMOLOGY; GENE DELETION; GENETICS; METABOLISM; MICROBIOLOGY; MUCOSA; PATHOGENICITY; STREPTOCOCCUS PNEUMONIAE;

BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE;

CA-125 ANTIGEN; CELL LINE; CELLS, CULTURED; EPITHELIAL CELLS; GLYCOCALYX; HUMANS; MEMBRANE PROTEINS; METALLOENDOPEPTIDASES; METALLOPROTEASES; MUCOUS MEMBRANE; SEQUENCE DELETION; STREPTOCOCCUS PNEUMONIAE;

EID: 84857828122     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032418     Document Type: Article

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