Mechanical loading up-regulates early remodeling signals from osteocytes subjected to physical damage

Journal of Biomechanics

Volumn 48, Issue 16, 2015, Pages 4221-4228

  Liu, Chao ^a   Zhang, Xiaoqing ^b   Wu, Michael ^c   You, Lidan ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Osteoclastogenesis; Osteocyte; PGE2; Physical damage; VEGF

Indexed keywords

CRACKS; SHEAR STRESS;

OSTEOCLASTOGENESIS; OSTEOCYTES; PGE2; PHYSICAL DAMAGES; VEGF;

SHEAR FLOW;

CYCLOOXYGENASE 2; INTERLEUKIN 6; MESSENGER RNA; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN; OSTEOCLAST DIFFERENTIATION FACTOR; PTGS2 PROTEIN, MOUSE; TNFSF11 PROTEIN, MOUSE; TRANSCRIPTOME; VASCULAR ENDOTHELIAL GROWTH FACTOR A, MOUSE; VASCULOTROPIN A;

ARTICLE; BONE MATRIX; BONE REMODELING; CELL DAMAGE; CELL DIFFERENTIATION; CELL LINE; CELL VIABILITY; CELLULAR DISTRIBUTION; CELLULAR STRESS RESPONSE; CONCENTRATION (PARAMETERS); IN VITRO STUDY; MECHANICAL STRESS; MLO Y4 CELL LINE; OSTEOCLAST; OSTEOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHEAR STRESS; UPREGULATION; ANIMAL; BIOMECHANICS; GENETICS; METABOLISM; MOUSE; PHYSIOLOGY; RAW 264.7 CELL LINE;

ANIMALS; BIOMECHANICAL PHENOMENA; BONE REMODELING; CYCLOOXYGENASE 2; DINOPROSTONE; INTERLEUKIN-6; MICE; OSTEOCYTES; RANK LIGAND; RAW 264.7 CELLS; RNA, MESSENGER; TRANSCRIPTOME; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84952876689     PISSN: 00219290     EISSN: 18732380     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2015.10.018     Document Type: Article

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