Vascular endothelial growth factor regulates osteoblast survival - Evidence for an autocrine feedback mechanism

Journal of Orthopaedic Surgery and Research

Volumn 4, Issue 1, 2009, Pages

  Street, John ^a,b   Lenehan, Brian ^a,b  

^a UNIVERSITY COLLEGE CORK   (Ireland)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 67651112022     PISSN: None     EISSN: 1749799X     Source Type: Journal    
DOI: 10.1186/1749-799X-4-19     Document Type: Article

References (33)

1. Biology of the basic multicellular unit and the pathophysiology of osteoporosis. RL Jilka, Med Pediatr Oncol 2003 41 3 182 5 10.1002/mpo.10334 12868116 (Pubitemid 36910125)
2. Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. SC Manolagas, Endocr Rev 2000 21 2 115 37 10.1210/er.21.2.115 10782361 (Pubitemid 32275592)
3. VEGF is required for growth and survival in neonatal mice. HP Gerber KJ Hillan AM Ryan J Kowalski GA Keller L Rangell BD Wright F Radtke M Aguet N Ferrara, Development 1999 126 6 1149 59 10021335
4. Expression of vascular endothelial growth factors and their receptors during osteoblast differentiation. MM Deckers M Karperien C van der Bent T Yamashita SE Papapoulos CW Lowik, Endocrinology 2000 141 5 1667 74 10.1210/en.141.5.1667 10803575 (Pubitemid 32274395)
5. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. HP Gerber A McMurtrey J Kowalski M Yan BA Keyt V Dixit N Ferrara, J Biol Chem 1998 273 46 30336 43 10.1074/jbc.273.46. 30336 9804796 (Pubitemid 28545503)
6. Is human fracture hematoma inherently angiogenic? J Street D Winter JH Wang A Wakai A McGuinness HP Redmond, Clin Orthop 2000 378 224 37 10986998
7. The angiogenic response to skeletal injury is preserved in the elderly. JT Street JH Wang QD Wu A Wakai A McGuinness HP Redmond, J Orthop Res 2001 19 6 1057 66 10.1016/S0736-0266(01)00048-1 11781005 (Pubitemid 33150182)
8. Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover. J Street M Bao L deGuzman S Bunting FV Peale Jr N Ferrara H Steinmetz J Hoeffel JL Cleland A Daugherty N van Bruggen HP Redmond RA Carano EH Filvaroff, Proc Natl Acad Sci USA 2002 99 15 9656 61 12118119 10.1073/pnas.152324099 (Pubitemid 34831103)
9. VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation. HP Gerber TH Vu AM Ryan J Kowalski Z Werb N Ferrara, Nat Med 1999 5 6 623 8 10.1038/9467 10371499 (Pubitemid 29289424)
10. Enhanced expression of vascular endothelial growth factor in human SaOS-2 osteoblast-like cells and murine osteoblasts induced by insulin-like growth factor I. DL Goad J Rubin H Wang AH Tashjian Jr C Patterson, Endocrinology 1996 137 6 2262 8 10.1210/en.137.6.2262 8641174 (Pubitemid 26155757)
11. Induction of vascular endothelial growth factor expression by prostaglandin E2 and E1 in osteoblasts. S Harada JA Nagy KA Sullivan KA Thomas N Endo GA Rodan SB Rodan, J Clin Invest 1994 93 6 2490 6 8200985 10.1172/JCI117258
12. Transforming growth factor-beta1 modulates the expression of vascular endothelial growth factor by osteoblasts. PB Saadeh BJ Mehrara DS Steinbrech ME Dudziak JA Greenwald JS Luchs JA Spector H Ueno GK Gittes MT Longaker, Am J Physiol 1999 277 4 Pt 1 C628 37 10516092
13. 1,25-Dihydroxyvitamin D3 induces the expression of vascular endothelial growth factor in osteoblastic cells. JM Schlaeppi S Gutzwiller G Finkenzeller B Fournier, Endocr Res 1997 23 3 213 29 9378108
14. VEGF expression in an osteoblast-like cell line is regulated by a hypoxia response mechanism. DS Steinbrech BJ Mehrara PB Saadeh JA Greenwald JA Spector GK Gittes MT Longaker, Am J Physiol Cell Physiol 2000 278 4 C853 60 10751333
15. Hypoxia couples the paracrine interaction between osteoblasts and endothelial cells. JT Street B Lenehan JH Wang A Wakai HP Redmond, European Journal of Orthopaedic Surgery and Traumatology 2005 15 3 214 225 10.1007/s00590-005-0232-z (Pubitemid 41414411)
16. Vascular endothelial growth factor can substitute for macrophage colony-stimulating factor in the support of osteoclastic bone resorption. S Niida M Kaku H Amano H Yoshida H Kataoka S Nishikawa K Tanne N Maeda S Nishikawa H Kodama, J Exp Med 1999 190 2 293 8 10432291 10.1084/jem.190.2.293 (Pubitemid 29354921)
17. Could apoptosis be responsible for localized imbalances in bone cell homeostasis? DR Clohisy, J Lab Clin Med 1999 134 3 190 1 10.1016/S0022-2143(99) 90197-X 10482302 (Pubitemid 29423090)
18. Staphylococcus aureus - induced tumor necrosis factor - related apoptosis - inducing ligand expression mediates apoptosis and caspase-8 activation in infected osteoblasts. EH Alexander FA Rivera I Marriott J Anguita KL Bost MC Hudson, BMC Microbiol 2003 3 1 5 12697056 10.1186/1471-2180-3-5
19. Multiple extracellular signals promote osteoblast survival and apoptosis. PA Hill A Tumber MC Meikle, Endocrinology 1997 138 9 3849 58 10.1210/en.138.9.3849 9275074 (Pubitemid 27351939)
20. Stemming bone loss by suppressing apoptosis. JM Hock, J Clin Invest 1999 104 4 371 3 10449428 10.1172/JCI7991
21. Osteoblast apoptosis and bone turnover. JM Hock V Krishnan JE Onyia JP Bidwell J Milas D Stanislaus, J Bone Miner Res 2001 16 6 975 84 10.1359/jbmr.2001.16.6.975 11393794
22. Osteoblast programmed cell death (apoptosis): modulation by growth factors and cytokines. RL Jilka RS Weinstein T Bellido AM Parfitt SC Manolagas, J Bone Miner Res 1998 13 5 793 802 10.1359/jbmr.1998.13.5.793 9610743 (Pubitemid 28224195)
23. Apoptosis is coordinately regulated with osteoblast formation during bone healing. P Landry K Sadasivan A Marino J Albright, Tissue Cell 1997 29 4 413 9 10.1016/S0040-8166(97)80027-4 9281844 (Pubitemid 27373098)
24. Programmed cell death in post-traumatic bone callus. ML Olmedo PS Landry KK Sadasivan JA Albright AA Marino, Cell Mol Biol (Noisy-le-grand) 2000 46 1 89 97 10726975
25. Matrix regulation of skeletal cell apoptosis. Role of calcium and phosphate ions. CS Adams K Mansfield RL Perlot IM Shapiro, J Biol Chem 2001 276 23 20316 22 10.1074/jbc.M006492200 11278303
26. Mechanisms by which extracellular matrix components induce osteoblast apoptosis. CS Adams IM Shapiro, Connect Tissue Res 2003 44 Suppl 1 230 9 10.1080/713713629 12952203
27. Rapid new bone tissue remodeling during distraction osteogenesis is associated with apoptosis. G Li GR Dickson DR Marsh H Simpson, J Orthop Res 2003 21 1 28 35 10.1016/S0736-0266(02)00097-9 12507577 (Pubitemid 36157617)
28. Angiogenesis in fracture repair. J Glowacki, Clin Orthop 1998 355 Suppl S82 9 9917629
29. Effect of 1alpha,25(OH)2-vitamin D3 on TNF alpha-mediated apoptosis of human primary osteoblast-like cells in vitro. E Pascher A Perniok A Becker J Feldkamp, Horm Metab Res 1999 31 12 653 6 10.1055/s-2007-978815 10668917
30. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. JA Forsythe BH Jiang NV Iyer F Agani SW Leung RD Koos GL Semenza, Mol Cell Biol 1996 16 9 4604 13 8756616
31. TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts. K Fuller B Wong S Fox Y Choi TJ Chambers, J Exp Med 1998 188 5 997 1001 9730902 10.1084/jem.188.5.997 (Pubitemid 28433427)
32. TGF-beta1 inhibits multiple caspases induced by TNF-alpha in murine osteoblastic MC3T3-E1 cells. CC Chua BH Chua Z Chen C Landy RC Hamdy, Biochim Biophys Acta 2002 1593 1 1 8 10.1016/S0167-4889(02)00257-4 12431778 (Pubitemid 35335906)
33. Tumor necrosis factor-alpha and interleukin-1beta increase the Fas-mediated apoptosis of human osteoblasts. M Tsuboi M Kaku H Amano H Yoshida H Kataoka S Nishikawa K Tanne N Maeda S Nishikawa H Kodama, J Lab Clin Med 1999 134 3 222 31 10.1016/S0022-2143(99)90201-9 10482306 (Pubitemid 29423094)