Systemic prostaglandin E2 increases cancellous bone formation and mass in aging rats and stimulates their bone marrow osteogenic capacity in vivo and in vitro

Journal of Endocrinology

Volumn 168, Issue 1, 2001, Pages 131-139

  Keila, S ^a   Kelner, A ^a   Weinreb, M ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

PROSTAGLANDIN E2;

AGED; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BONE MARROW; BONE MASS; CANCELLOUS BONE; CONTROLLED STUDY; MALE; METAPHYSIS; NONHUMAN; OSSIFICATION; OSTEOBLAST; PRIORITY JOURNAL; RAT; STROMA CELL; TIBIA; ANALYSIS OF VARIANCE; ANIMAL; BONE MARROW CELL; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; DRUG EFFECT; PHYSIOLOGY; SPRAGUE DAWLEY RAT; STIMULATION;

AGING; ANALYSIS OF VARIANCE; ANIMALS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELLS, CULTURED; DINOPROSTONE; MALE; OSTEOBLASTS; OSTEOGENESIS; RATS; RATS, SPRAGUE-DAWLEY; STIMULATION, CHEMICAL;

EID: 0034746416     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1680131     Document Type: Article

References (38)

1. 2 prevents bone loss and adds extra bone to immobilized distal femoral metaphysis in female rats
2. Age-related changes in osteogenic stem cells in mice
3. Age-associated decline in human femoral neck cortical and trabecular content of IGF-I: Potential implications for age-related (type II) osteoporotic fracture occurrence
4. Evidence for both generalized and regional low bone mass among elderly women
5. Age-related osteogenic potential of mesenchymal stromal stem cells from human vertebral bone marrow
6. The number of fibroblastic colonies formed from bone marrow is decreased and the in vitro proliferation rate of trabecular bone cells increased in aged animals
7. Osteogenic stern cells in the bone marrow
8. Heterotopic transplantation of bone marrow: Analysis of precursor cells for osteogenic and hemopoietic tissues
9. Bone loss (osteopenia) in old male mice results from diminished activity and availability of TGFβ
10. The decrease in bone mass associated with aging and menopause
11. The effect of aging on bone formation in porous hydroxyapatite: Biochemical and histological analysis
12. In vivo anabolic actions of prostaglandins in bone
13. 2
14. 2 prevents disuse-induced cortical bone loss
15. 2 administration
16. Age-related bone loss. A hypothesis and initial assessment in mice
17. 2 on bone after its withdrawal in rats
18. 2 on maintaining elevated proximal tibial metaphyseal cancellous bone mass in male rats
19. Bone marrow from mechanically unloaded rat bones expresses reduced osteogenic capacity in vitro
20. Bone formation in vitro by stromal cells obtained from bone marrow of young adult rats
21. Osteoporosis and the replacement of cell populations of the marrow by adipose tissue
22. 2 on production of new cancellous bone in the axial skeleton of ovariectomized rats
23. The role of prostaglandins in bone in vivo. A review
24. Marrow stromal stem cells
25. Bone histomorphometry: Standardization of nomenclature, symbols and units
26. Relations between histologic indices of bone formation: Implications for the pathogenesis of spinal osteoporosis
27. Bone progenitor cell deficits and the age-associated decline in bone repair capacity
28. Determinants of peak bone mass and mechanisms of bone loss
29. The in vivo role of bone marrow fibroblast-like stromal cells
30. 2 in long bones and calvariae of young rats
31. Effect of donor age on osteogenic cells of rat bone marrow in vitro
32. 1
33. 2 in rapidly growing rats: Depressed longitudinal and radial growth and increased metaphyseal hard tissue mass
34. Depression of osteoblastic activity in immobilized limbs of suckling rats
35. 2 in young rats increases the osteogenic capacity of bone marrow
36. 2 induces early-response genes in rat bones
37. 4 receptor subtype
38. 2 on cortical bone of aged male rats comes mainly from modeling-dependent bone gain