메뉴 건너뛰기




Volumn 214, Issue 2, 2008, Pages 537-544

Evaluation of VEGF-mediated signaling in primary human cells reveals a paracrine action for VEGF in osteoblast-mediated crosstalk to endothelial cells

Author keywords

[No Author keywords available]

Indexed keywords

6 OXOPROSTAGLANDIN F1 ALPHA; ALKALINE PHOSPHATASE; CYCLOOXYGENASE 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROSTACYCLIN; PROSTAGLANDIN DERIVATIVE; PROSTAGLANDIN E2; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

EID: 37349095299     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21234     Document Type: Article
Times cited : (134)

References (57)
  • 1
    • 0030908042 scopus 로고    scopus 로고
    • Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells
    • Abedi H, Zachary I. 1997. Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells. J Biol Chem 272:15442-15451.
    • (1997) J Biol Chem , vol.272 , pp. 15442-15451
    • Abedi, H.1    Zachary, I.2
  • 2
    • 0036153327 scopus 로고    scopus 로고
    • Induction of vascular endothelial growth factor by IGF-1 in osteoblast-like cells is mediated by the PI3K signaling pathway through the hypoxia-inducible factor-2{alpha}
    • Akeno N, Robins J, Zhang M, Czyzyk-Krzeska MF, Clemens TL. 2002. Induction of vascular endothelial growth factor by IGF-1 in osteoblast-like cells is mediated by the PI3K signaling pathway through the hypoxia-inducible factor-2{alpha}. Endocrinology 143:420-425.
    • (2002) Endocrinology , vol.143 , pp. 420-425
    • Akeno, N.1    Robins, J.2    Zhang, M.3    Czyzyk-Krzeska, M.F.4    Clemens, T.L.5
  • 3
    • 15744364847 scopus 로고    scopus 로고
    • Selective activation of the MEK-ERK pathway is regulated by mechanical stimuli in forming joints and promotes pericellular matrix formation
    • Bastow ER, Lamb KJ, Lewthwaite JC, Osborne AC, Kavanagh E, Wheeler-Jones CPD. Pitsillides AA. 2005. Selective activation of the MEK-ERK pathway is regulated by mechanical stimuli in forming joints and promotes pericellular matrix formation. J Biol Chem 280:11749-11758.
    • (2005) J Biol Chem , vol.280 , pp. 11749-11758
    • Bastow, E.R.1    Lamb, K.J.2    Lewthwaite, J.C.3    Osborne, A.C.4    Kavanagh, E.5    Wheeler-Jones, C.P.D.6    Pitsillides, A.A.7
  • 4
    • 0032004869 scopus 로고    scopus 로고
    • Role of subchondral vascular system in endochondral ossification: Endothelial cells specifically depress late differentiation in resting chondrocytes in vitro
    • Bittner K, Vischer P, Bartholmes P, Bruckner P. 1998. Role of subchondral vascular system in endochondral ossification: Endothelial cells specifically depress late differentiation in resting chondrocytes in vitro. Exp Cell Res 238:491-497.
    • (1998) Exp Cell Res , vol.238 , pp. 491-497
    • Bittner, K.1    Vischer, P.2    Bartholmes, P.3    Bruckner, P.4
  • 5
    • 0032530319 scopus 로고    scopus 로고
    • Activated endothelial cells elicit paracrine induction of epithelial chloride secretion. 6-Keto-PGF1alpha is an epithelial secretagogue
    • Blume ED, Taylor CT, Lennon PF, Stahl GL, Colgan SP. 1998. Activated endothelial cells elicit paracrine induction of epithelial chloride secretion. 6-Keto-PGF1alpha is an epithelial secretagogue. J Clin Invest 102:1161-1172.
    • (1998) J Clin Invest , vol.102 , pp. 1161-1172
    • Blume, E.D.1    Taylor, C.T.2    Lennon, P.F.3    Stahl, G.L.4    Colgan, S.P.5
  • 7
    • 0025356926 scopus 로고
    • Microvascular invasion of rabbit growth plate cartilage and the influence of dexamethasone
    • Brown RA, Rees JA, Mcfarland CD, Lewinson D, Ali SY. 1990. Microvascular invasion of rabbit growth plate cartilage and the influence of dexamethasone. J Bone Miner Res 9:35-47.
    • (1990) J Bone Miner Res , vol.9 , pp. 35-47
    • Brown, R.A.1    Rees, J.A.2    Mcfarland, C.D.3    Lewinson, D.4    Ali, S.Y.5
  • 8
    • 0023276009 scopus 로고
    • Changes in trabecular bone hematopoiesis and bone marrow vessels in aplastic anemia, primary osteoporosis and old age: A comparative histomorphometric study
    • Burkhardt R, Kettner G, Bohm W, Schmidmeier M, Shalag R, Frisch B, Mallmann B, Eisenmenger W, Gilg TH. 1987. Changes in trabecular bone hematopoiesis and bone marrow vessels in aplastic anemia, primary osteoporosis and old age: A comparative histomorphometric study. Bone 8:564-571.
    • (1987) Bone , vol.8 , pp. 564-571
    • Burkhardt, R.1    Kettner, G.2    Bohm, W.3    Schmidmeier, M.4    Shalag, R.5    Frisch, B.6    Mallmann, B.7    Eisenmenger, W.8    Gilg, T.H.9
  • 9
    • 0026211855 scopus 로고
    • Parallels between development of embryonic and matrix induced endochondral bone
    • Carringdon JL, Reddi AH. 1991. Parallels between development of embryonic and matrix induced endochondral bone. Bioessays 13:403-406.
    • (1991) Bioessays , vol.13 , pp. 403-406
    • Carringdon, J.L.1    Reddi, A.H.2
  • 10
    • 33644797160 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinases and AP-1 mediate the up-regulation of vascular endothelial growth factor by PDGF in human vascular smooth muscle cells
    • Chang HJ, Park JS, Kim MH, Hong MH, Kim KM, Kim SM, Shin BA, Ahn BW, Jung YD. 2006. Extracellular signal-regulated kinases and AP-1 mediate the up-regulation of vascular endothelial growth factor by PDGF in human vascular smooth muscle cells. Int J Oncol 28:135-141.
    • (2006) Int J Oncol , vol.28 , pp. 135-141
    • Chang, H.J.1    Park, J.S.2    Kim, M.H.3    Hong, M.H.4    Kim, K.M.5    Kim, S.M.6    Shin, B.A.7    Ahn, B.W.8    Jung, Y.D.9
  • 11
    • 3142757185 scopus 로고    scopus 로고
    • Anti-chemorepulsive effects of vascular endothelial growth factor and placental growth factor-2 in dorsal root ganglion neurons are mediated by neuropilin-1 and cyclooxygenase-derived prostanoid production
    • Cheng L, Jia H, Lohr M, Bagherzadeh A, Holmes DIR, Selwood D, Zachary I. 2004. Anti-chemorepulsive effects of vascular endothelial growth factor and placental growth factor-2 in dorsal root ganglion neurons are mediated by neuropilin-1 and cyclooxygenase-derived prostanoid production. J Biol Chem 279:30654-30661.
    • (2004) J Biol Chem , vol.279 , pp. 30654-30661
    • Cheng, L.1    Jia, H.2    Lohr, M.3    Bagherzadeh, A.4    Holmes, D.I.R.5    Selwood, D.6    Zachary, I.7
  • 12
    • 0038446575 scopus 로고    scopus 로고
    • Endothelial COX-2 induction by hypoxia liberates 6-ketoPGF1a, a potent epithelial secretagogue
    • Colgan SP, Taylor CT, Narravula S, Synnestvedt K, Blume ED. 2002. Endothelial COX-2 induction by hypoxia liberates 6-ketoPGF1a, a potent epithelial secretagogue. Adv Exp Med Biol 507:107-112.
    • (2002) Adv Exp Med Biol , vol.507 , pp. 107-112
    • Colgan, S.P.1    Taylor, C.T.2    Narravula, S.3    Synnestvedt, K.4    Blume, E.D.5
  • 13
    • 0029043575 scopus 로고
    • Relationships between endothelial cells, pericytes and osteoblasts during bone formation in the sheep femur following inplantation of tricalciumphosphate ceramic
    • Deckers B, Bartels H, Deckers S. 1995. Relationships between endothelial cells, pericytes and osteoblasts during bone formation in the sheep femur following inplantation of tricalciumphosphate ceramic. Anat Rec 242:310-320.
    • (1995) Anat Rec , vol.242 , pp. 310-320
    • Deckers, B.1    Bartels, H.2    Deckers, S.3
  • 15
    • 33645500619 scopus 로고    scopus 로고
    • Angiogenesis-like activity of endothelial cells co-cultured with VEGF-producing smooth muscle cells
    • Elbjeirami WM, West JL. 2006. Angiogenesis-like activity of endothelial cells co-cultured with VEGF-producing smooth muscle cells. Tissue Eng 12:381-390.
    • (2006) Tissue Eng , vol.12 , pp. 381-390
    • Elbjeirami, W.M.1    West, J.L.2
  • 16
    • 0034121663 scopus 로고    scopus 로고
    • C-terminal parathyroid hormone-related protein increases vascular endothelial growth factor in human osteoblastic cells
    • Esbrit P, Alvarez-Arroyo M, De Miguel F, Martin O, Martinez M, Caramelo C. 2000. C-terminal parathyroid hormone-related protein increases vascular endothelial growth factor in human osteoblastic cells. J Am Soc Nephrol 11:1085-1092.
    • (2000) J Am Soc Nephrol , vol.11 , pp. 1085-1092
    • Esbrit, P.1    Alvarez-Arroyo, M.2    De Miguel, F.3    Martin, O.4    Martinez, M.5    Caramelo, C.6
  • 17
    • 0030500444 scopus 로고    scopus 로고
    • Vascular endothelial growth factor
    • Ferrara N. 1996. Vascular endothelial growth factor. Eur J Cancer 32A:2413-2422.
    • (1996) Eur J Cancer , vol.32 A , pp. 2413-2422
    • Ferrara, N.1
  • 19
    • 3442877507 scopus 로고    scopus 로고
    • VEGF-R2 and neuropilin-1 are involved in VEGF-A- induced differentiation of human bone marrow progenitor cells
    • Fons P, Herault JP, Delesque N, Tuyaret J, Bono F, Herbert JM. 2004. VEGF-R2 and neuropilin-1 are involved in VEGF-A- induced differentiation of human bone marrow progenitor cells. J Cell Physiol 200:351-359.
    • (2004) J Cell Physiol , vol.200 , pp. 351-359
    • Fons, P.1    Herault, J.P.2    Delesque, N.3    Tuyaret, J.4    Bono, F.5    Herbert, J.M.6
  • 22
    • 0033027858 scopus 로고    scopus 로고
    • VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation
    • Gerber H, Vu TH, Ryan A, Kowalski J, Werb Z, Ferrara N. 1999. VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation. Nat Med 5:623-628.
    • (1999) Nat Med , vol.5 , pp. 623-628
    • Gerber, H.1    Vu, T.H.2    Ryan, A.3    Kowalski, J.4    Werb, Z.5    Ferrara, N.6
  • 23
    • 37349080206 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-induced prostacyclin production is mediated by a protein kinase C (PKC)-dependent activation of extracellular signal-regulated protein kinases 1 and 2 involving PKC- and by mobilization of intracellular Ca2+
    • Gliki G, Abu-ghazaleh R, Jezequel S, Wheeler-jones C, Zachary I. 2001. Vascular endothelial growth factor-induced prostacyclin production is mediated by a protein kinase C (PKC)-dependent activation of extracellular signal-regulated protein kinases 1 and 2 involving PKC- and by mobilization of intracellular Ca2+. J Biochem 535:503-512.
    • (2001) J Biochem , vol.535 , pp. 503-512
    • Gliki, G.1    Abu-ghazaleh, R.2    Jezequel, S.3    Wheeler-jones, C.4    Zachary, I.5
  • 26
    • 0034874481 scopus 로고    scopus 로고
    • Cancellous bone remodeling occurs in specialized compartments lined by cells expressing osteoblastic markers
    • Hauge EM, Qvesel D, Eriksen EF, Mosekilde L, Meisen F. 2001. Cancellous bone remodeling occurs in specialized compartments lined by cells expressing osteoblastic markers. J Bone Miner Res 16:1575-1582.
    • (2001) J Bone Miner Res , vol.16 , pp. 1575-1582
    • Hauge, E.M.1    Qvesel, D.2    Eriksen, E.F.3    Mosekilde, L.4    Meisen, F.5
  • 29
    • 0032542763 scopus 로고    scopus 로고
    • Expression of cycoloxygenase 1 (COX-1) and cycoloxygenase 2 in human breast cancer
    • Hwang D, Scollard D, Byrne J, Levine E. 1998. Expression of cycoloxygenase 1 (COX-1) and cycoloxygenase 2 in human breast cancer. J Natl Cancer Inst 90:455-460.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 455-460
    • Hwang, D.1    Scollard, D.2    Byrne, J.3    Levine, E.4
  • 30
    • 0036551229 scopus 로고    scopus 로고
    • Suppression of prostaglandin synthesis with NS-398 has different effects on endocortical and periosteal bone formation induced by mechanical loading
    • Li J, Burr DB, Turner CH. 2002. Suppression of prostaglandin synthesis with NS-398 has different effects on endocortical and periosteal bone formation induced by mechanical loading. Calcif Tissue Int 70:320-329.
    • (2002) Calcif Tissue Int , vol.70 , pp. 320-329
    • Li, J.1    Burr, D.B.2    Turner, C.H.3
  • 33
    • 0028237788 scopus 로고
    • Vasculotropin/vascular endothelial growth factor induces differentiation cultured osteoblasts
    • Midy V, Plouet J. 1994. Vasculotropin/vascular endothelial growth factor induces differentiation cultured osteoblasts. Biochem Biophys Res Commun 199:380-386.
    • (1994) Biochem Biophys Res Commun , vol.199 , pp. 380-386
    • Midy, V.1    Plouet, J.2
  • 34
    • 33846605653 scopus 로고    scopus 로고
    • Static strain stimulates expression of matrix metalloproteinase-2 and VEGF in microvascular endothelium via JNK- and ERK-dependent pathways
    • Milkiewicz M, Mohammadzadeh F, Ispanovi E, Gee E, Haas T. 2007. Static strain stimulates expression of matrix metalloproteinase-2 and VEGF in microvascular endothelium via JNK- and ERK-dependent pathways. J Cell Biochem 100:750-761.
    • (2007) J Cell Biochem , vol.100 , pp. 750-761
    • Milkiewicz, M.1    Mohammadzadeh, F.2    Ispanovi, E.3    Gee, E.4    Haas, T.5
  • 35
    • 33750074755 scopus 로고    scopus 로고
    • Hypoxia increases VEGF-A production by prostate cancer and bone marrow stromal cells and initiates paracrine activation of bone marrow endothelial cells
    • Muir C, Leland WK, Chung LW, Carson DD, Farach-Carson M. 2006. Hypoxia increases VEGF-A production by prostate cancer and bone marrow stromal cells and initiates paracrine activation of bone marrow endothelial cells. Clin Exp Metastasis 23:75-86.
    • (2006) Clin Exp Metastasis , vol.23 , pp. 75-86
    • Muir, C.1    Leland, W.K.2    Chung, L.W.3    Carson, D.D.4    Farach-Carson, M.5
  • 36
    • 15444378057 scopus 로고    scopus 로고
    • 165-induced prostacyclin synthesis requires the activation of VEGF receptor-1 and -2 heterodimer
    • 165-induced prostacyclin synthesis requires the activation of VEGF receptor-1 and -2 heterodimer. J Biol Chem 280:9904-9912.
    • (2005) J Biol Chem , vol.280 , pp. 9904-9912
    • Neagoe, P.-E.1    Lemieux, C.2    Sirois, M.G.3
  • 38
    • 0033022861 scopus 로고    scopus 로고
    • Bone's early responses to mechanical loading differ in distinct genetic strains of chick: Selection for enhanced growth reduces skeletal adaptability
    • Pitsillides AA, Rawlinson SC, Mosley JR, Lanyon LE. 1999. Bone's early responses to mechanical loading differ in distinct genetic strains of chick: Selection for enhanced growth reduces skeletal adaptability. J Bone Miner Res 14:980-987.
    • (1999) J Bone Miner Res , vol.14 , pp. 980-987
    • Pitsillides, A.A.1    Rawlinson, S.C.2    Mosley, J.R.3    Lanyon, L.E.4
  • 40
    • 0033941227 scopus 로고    scopus 로고
    • Arachidonic acid for loading induced prostacyclin and prostaglandin E2 release from osteoblasts and osteocytes is derived from the activities of different forms of phospholipase A2
    • Rawlinson SCF, Wheeler-Jones CPD, Lanyon LE. 2000. Arachidonic acid for loading induced prostacyclin and prostaglandin E2 release from osteoblasts and osteocytes is derived from the activities of different forms of phospholipase A2. Bone 27:241-247.
    • (2000) Bone , vol.27 , pp. 241-247
    • Rawlinson, S.C.F.1    Wheeler-Jones, C.P.D.2    Lanyon, L.E.3
  • 41
    • 33744757680 scopus 로고    scopus 로고
    • Role of lymphangiogenesis and lymphangiogenic factors during pancreatic cancer progression and lymphatic spread
    • Schneider M, Buchler P, Giese N, Giese T, Wilting J, Buchler MW, Friess H. 2006. Role of lymphangiogenesis and lymphangiogenic factors during pancreatic cancer progression and lymphatic spread. Int J Oncol 28:883-890.
    • (2006) Int J Oncol , vol.28 , pp. 883-890
    • Schneider, M.1    Buchler, P.2    Giese, N.3    Giese, T.4    Wilting, J.5    Buchler, M.W.6    Friess, H.7
  • 42
    • 0023354121 scopus 로고
    • Mineralisation of normal and rachitic chick growth cartilage: Vascular canals, cartilage calicification and osteogenenesis
    • Shapiro IM, Boyde A. 1987. Mineralisation of normal and rachitic chick growth cartilage: Vascular canals, cartilage calicification and osteogenenesis. Scanning Microsc 1:599-606.
    • (1987) Scanning Microsc , vol.1 , pp. 599-606
    • Shapiro, I.M.1    Boyde, A.2
  • 43
    • 0025085822 scopus 로고
    • Relationship of cell growth to the regulation of tissue-specific gene expression during osteoblast differentiation
    • Stein GS, Lian JB, Owen TA. 1990. Relationship of cell growth to the regulation of tissue-specific gene expression during osteoblast differentiation. FASEB J 4:3111-3123.
    • (1990) FASEB J , vol.4 , pp. 3111-3123
    • Stein, G.S.1    Lian, J.B.2    Owen, T.A.3
  • 44
    • 33744958661 scopus 로고    scopus 로고
    • Cyclooxygenase-2 induction and prostacyclin release by protease-activated receptors in endothelial cells require cooperation between mitogen-activated protein kinase and NF-{kappa}B pathways
    • Syeda F, Grosjean J, Houliston RA, Keogh RJ, Carter TD, Paleolog E, Wheeler-Jones CPD. 2006. Cyclooxygenase-2 induction and prostacyclin release by protease-activated receptors in endothelial cells require cooperation between mitogen-activated protein kinase and NF-{kappa}B pathways. J Biol Chem 281:11792-11804.
    • (2006) J Biol Chem , vol.281 , pp. 11792-11804
    • Syeda, F.1    Grosjean, J.2    Houliston, R.A.3    Keogh, R.J.4    Carter, T.D.5    Paleolog, E.6    Wheeler-Jones, C.P.D.7
  • 45
    • 0033118228 scopus 로고    scopus 로고
    • VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase for DNA synthesis in primary endothelial cells
    • Takahashi T, Ueno H, Shibuya M. 1999. VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase for DNA synthesis in primary endothelial cells. Oncogene 18:2221-2230.
    • (1999) Oncogene , vol.18 , pp. 2221-2230
    • Takahashi, T.1    Ueno, H.2    Shibuya, M.3
  • 46
    • 1542616911 scopus 로고    scopus 로고
    • Osteoblast and osteoclasts express PEDF, VEGF-A isoforms, and VEGF receptors: Possible mediators of angiogenesis and matrix remodelling in bone
    • Tombran-Tink J, Barnstable CJ. 2004. Osteoblast and osteoclasts express PEDF, VEGF-A isoforms, and VEGF receptors: Possible mediators of angiogenesis and matrix remodelling in bone. Biochem Biophys Res Commun 316:573-579.
    • (2004) Biochem Biophys Res Commun , vol.316 , pp. 573-579
    • Tombran-Tink, J.1    Barnstable, C.J.2
  • 47
    • 0000123919 scopus 로고
    • The role of the vessels in osteogenesis
    • Trueta J. 1963. The role of the vessels in osteogenesis. J Bone Joint Surg 45-B:402-418.
    • (1963) J Bone Joint Surg , vol.45-B , pp. 402-418
    • Trueta, J.1
  • 48
    • 0002420684 scopus 로고
    • The vascular contribution to osteogenesis. II. Studies with the electron microscope
    • Trueta J, Little K. 1960. The vascular contribution to osteogenesis. II. Studies with the electron microscope. J Bone Joint Surg 42:367-376.
    • (1960) J Bone Joint Surg , vol.42 , pp. 367-376
    • Trueta, J.1    Little, K.2
  • 49
    • 29444438572 scopus 로고    scopus 로고
    • 200S. Paracrine regulation of vascular endothelial growth factor - a expression during macrophage-melanoma cell interaction: Role of monocyte chemotactic protein-1 and macrophage colony-stimulating factor
    • Varney ML, Olsen KJ, Mosley RL, Singh RK. 200S. Paracrine regulation of vascular endothelial growth factor - a expression during macrophage-melanoma cell interaction: Role of monocyte chemotactic protein-1 and macrophage colony-stimulating factor. J Interferon Cytokine Res 25:674-683.
    • J Interferon Cytokine Res , vol.25 , pp. 674-683
    • Varney, M.L.1    Olsen, K.J.2    Mosley, R.L.3    Singh, R.K.4
  • 50
    • 37349101253 scopus 로고    scopus 로고
    • Increase of vascular endothelial growth factor mRNA expression produced by osteoblasts and by growth factors produced by endothelial cells
    • Wang DS, Yamazazaki K, Nohtomi K, Shizume K, Ohsumi K, Shibuya M, Demura H, Sato K. 1996. Increase of vascular endothelial growth factor mRNA expression produced by osteoblasts and by growth factors produced by endothelial cells. Endocrinology 138:2953-2962.
    • (1996) Endocrinology , vol.138 , pp. 2953-2962
    • Wang, D.S.1    Yamazazaki, K.2    Nohtomi, K.3    Shizume, K.4    Ohsumi, K.5    Shibuya, M.6    Demura, H.7    Sato, K.8
  • 51
    • 0009877834 scopus 로고    scopus 로고
    • Anabolic effects of 1,25-dihydroxyvitamin D3 on osteoblasts are enhanced by vascular endothelial growth factor produced by osteoblasts and by growth factors produced by endothelial cells
    • Wang DS, Miura M, Demura H, Sato K. 1997. Anabolic effects of 1,25-dihydroxyvitamin D3 on osteoblasts are enhanced by vascular endothelial growth factor produced by osteoblasts and by growth factors produced by endothelial cells. Endocrinology 138:2953-2962.
    • (1997) Endocrinology , vol.138 , pp. 2953-2962
    • Wang, D.S.1    Miura, M.2    Demura, H.3    Sato, K.4
  • 52
    • 37349026932 scopus 로고    scopus 로고
    • Vascular endothelial growth factor stimulates prostacylin production and activation of cytosolic phospholipase A in endothelial cells via p42/p44 mitogen activated kinase
    • Wheeler-Jones CPD, Abu-Ghazaleh R, Cospedal R. 1997. Vascular endothelial growth factor stimulates prostacylin production and activation of cytosolic phospholipase A in endothelial cells via p42/p44 mitogen activated kinase. FEBS Lett 353:503-512.
    • (1997) FEBS Lett , vol.353 , pp. 503-512
    • Wheeler-Jones, C.P.D.1    Abu-Ghazaleh, R.2    Cospedal, R.3
  • 56
    • 0035920244 scopus 로고    scopus 로고
    • Vascular permeability factor (VPF)/vascular endothelial growth factor (VEGF) receptor-1 down-modulates VPF/VEGF receptor-2-mediated endothelial cell proliferation, but not migration, through phosphatidylinositol 3-kinase-dependent pathways
    • Zeng H, Dvorak HF, Mukhopadhyay D. 2001. Vascular permeability factor (VPF)/vascular endothelial growth factor (VEGF) receptor-1 down-modulates VPF/VEGF receptor-2-mediated endothelial cell proliferation, but not migration, through phosphatidylinositol 3-kinase-dependent pathways. J Biol Chem 276:26969-26979.
    • (2001) J Biol Chem , vol.276 , pp. 26969-26979
    • Zeng, H.1    Dvorak, H.F.2    Mukhopadhyay, D.3
  • 57
    • 0036259278 scopus 로고    scopus 로고
    • Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair
    • Zhang X, Schwartz EM, Young DA, Puzas E, Rosier RN, O'Keefe RJ. 2002. Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair. J Clin Invest 109:1405-1415.
    • (2002) J Clin Invest , vol.109 , pp. 1405-1415
    • Zhang, X.1    Schwartz, E.M.2    Young, D.A.3    Puzas, E.4    Rosier, R.N.5    O'Keefe, R.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.