Structural and biochemical characterization of GTP cyclohydrolase II from Helicobacter pylori reveals its redox dependent catalytic activity

Journal of Structural Biology

Volumn 192, Issue 1, 2015, Pages 100-115

  Yadav, Savita ^a   Karthikeyan, Subramanian ^a  

^a INSTITUTE OF MICROBIAL TECHNOLOGY   (India)

Author keywords

Antimicrobial; FAD; FMN; GCHII; RibA; Riboflavin

Indexed keywords

CHLORPHENOTANE; CYSTEINE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE II; HYDROGEN PEROXIDE; THIOMESYLIC ACID METHYL ESTER; ZINC ION; 5'-GUANYLYLMETHYLENEBISPHOSPHONATE; BACTERIAL PROTEIN; GUANOSINE TRIPHOSPHATE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; PEPTIDE FRAGMENT; PROTEIN BINDING;

ARTICLE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISULFIDE BOND; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME REGULATION; ENZYME STRUCTURE; HELICOBACTER PYLORI; MASS SPECTROMETRY; NONHUMAN; OXIDATION; OXIDATION REDUCTION REACTION; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; AMINO ACID SEQUENCE; ANALOGS AND DERIVATIVES; CHEMICAL STRUCTURE; CHEMISTRY; CONSERVED SEQUENCE; ENZYMOLOGY; KINETICS; MOLECULAR GENETICS; PROTEIN SECONDARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CATALYTIC DOMAIN; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; GTP CYCLOHYDROLASE; GUANOSINE TRIPHOSPHATE; HELICOBACTER PYLORI; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY;

EID: 84952873470     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2015.08.004     Document Type: Article

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