Renal carcinogenesis in models of diabetes in rats - Metabolic changes are closely related to neoplastic development

Diabetologia

Volumn 50, Issue 12, 2007, Pages 2580-2590

  Dombrowski, F ^a   Klotz, L ^b   Bannasch, P ^c   Evert, M ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

^b UNIVERSITY OF BONN   (Germany)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Armanni Ebstein lesion; Diabetes mellitus; Diabetic tubulopathy; Hyperglycaemia; IGF; Insulin; Nephrocarcinogenesis; Renal cell carcinoma; TGF

Indexed keywords

CYTOKERATIN 7; EPIDERMAL GROWTH FACTOR RECEPTOR; GEFITINIB; GLUCOSE 6 PHOSPHATASE; GLYCOGEN PHOSPHORYLASE; GLYCOGEN SYNTHASE; INSULIN RECEPTOR SUBSTRATE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; SOMATOMEDIN B; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; TRANSFORMING GROWTH FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARMANNI EBSTEIN LESION; ARTICLE; CANCER RISK; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; HYPERGLYCEMIA; KIDNEY CARCINOMA; KIDNEY DISEASE; KIDNEY DISTAL TUBULE; KIDNEY PROXIMAL TUBULE; LEUKEMIA; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; STREPTOZOCIN DIABETES; TUMOR VOLUME; VIRUS ONCOGENE;

ANIMALS; CARCINOMA, RENAL CELL; CELL PROLIFERATION; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KERATIN-7; KIDNEY; KIDNEY NEOPLASMS; MALE; PRECANCEROUS CONDITIONS; RATS; RATS, INBRED LEW; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STREPTOZOCIN; TIME FACTORS;

EID: 35848941694     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-007-0838-2     Document Type: Article

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