Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice with Activated KRAS

Gastroenterology

Volumn 150, Issue 1, 2016, Pages 218-228.e12

  Qiu, Wanglong ^a   Tang, Sophia M ^a   Lee, Sohyae ^a   Turk, Andrew T ^a   Sireci, Anthony N ^a   Qiu, Anne ^a   Rose, Christian ^b   Xie, Chuangao ^a   Kitajewski, Jan ^a   Wen, Hui Ju ^c   Crawford, Howard C ^c   Sims, Peter A ^a   Hruban, Ralph H ^d   Remotti, Helen E ^a   Su, Gloria H ^a  

^a NewYork Presbyterian Hospital   (United States)

^b Plexus Medical Art   (United States)

^c MAYO CLINIC   (United States)

^d DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

Pancreas; PDA; TGF Superfamily; Tumor Suppressor

Indexed keywords

ACTIVIN RECEPTOR 1; ACTIVIN RECEPTOR 1B; CD20 ANTIGEN; CD3 ANTIGEN; GENOMIC DNA; K RAS PROTEIN; NOTCH4 RECEPTOR; PROTEIN P16; RNA; UNCLASSIFIED DRUG; ACRV1 PROTEIN, MOUSE; KRAS2 PROTEIN, MOUSE; MEMBRANE PROTEIN; PROTEIN P21;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CANCER SURVIVAL; CARCINOGENESIS; CELL INFILTRATION; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE COURSE; GENE ACTIVATION; GENE DELETION; IMMUNOHISTOCHEMISTRY; INDEL MUTATION; INTRADUCTAL PAPILLARY MUCINOUS TUMOR; MOUSE; NONHUMAN; PANCREAS ADENOCARCINOMA; PANCREATIC TISSUE; PRIORITY JOURNAL; PROTEIN DEPLETION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SOMATIC MUTATION; TUMOR INVASION; ANIMAL; COLLOID CARCINOMA; DISEASE MODEL; GENETIC PREDISPOSITION; GENETICS; HUMAN; KNOCKOUT MOUSE; MALE; MORTALITY; PANCREAS CARCINOMA; PANCREAS TUMOR; PATHOLOGY; RANDOMIZATION; REAL TIME POLYMERASE CHAIN REACTION; SURVIVAL RATE; TUMOR SUPPRESSOR GENE;

ADENOCARCINOMA, MUCINOUS; ANIMALS; CARCINOGENESIS; CARCINOMA, PANCREATIC DUCTAL; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; GENE DELETION; GENES, TUMOR SUPPRESSOR; GENETIC PREDISPOSITION TO DISEASE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; PANCREATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS P21(RAS); RANDOM ALLOCATION; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SURVIVAL RATE;

EID: 84952685089     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2015.09.013     Document Type: Article

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