메뉴 건너뛰기




Volumn 35, Issue 11, 2015, Pages 939-947

Genetic and epigenetic transgenerational implications related to omega-3 fatty acids. Part I: Maternal FADS2 genotype and DNA methylation correlate with polyunsaturated fatty acid status in toddlers: An exploratory analysis

Author keywords

Dietary intakes; DNA methylation; FADS2; Nutrigenomics; Polyunsaturated fatty acids

Indexed keywords

ACYL COENZYME A DESATURASE; ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; DOCOSAPENTAENOIC ACID; GENOMIC DNA; ICOSAPENTAENOIC ACID; LINOLENIC ACID; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; POLYUNSATURATED FATTY ACID; PROTEIN FADS2; UNCLASSIFIED DRUG; FADS2 PROTEIN, HUMAN; UNSATURATED FATTY ACID;

EID: 84952639014     PISSN: 02715317     EISSN: 18790739     Source Type: Journal    
DOI: 10.1016/j.nutres.2015.09.004     Document Type: Article
Times cited : (20)

References (26)
  • 1
    • 70350059182 scopus 로고    scopus 로고
    • Alpha-linolenic acid and its conversion to longer chain n-3 fatty acids: benefits for human health and a role in maintaining tissue n-3 fatty acid levels
    • Barcelo-Coblijn G., Murphy E.J. Alpha-linolenic acid and its conversion to longer chain n-3 fatty acids: benefits for human health and a role in maintaining tissue n-3 fatty acid levels. Prog Lipid Res 2009, 48:355-374.
    • (2009) Prog Lipid Res , vol.48 , pp. 355-374
    • Barcelo-Coblijn, G.1    Murphy, E.J.2
  • 2
    • 34447331361 scopus 로고    scopus 로고
    • Extremely limited synthesis of long chain polyunsaturates in adults: implications for their dietary essentiality and use as supplements
    • Plourde M., Cunnane S.C. Extremely limited synthesis of long chain polyunsaturates in adults: implications for their dietary essentiality and use as supplements. Appl Physiol Nutr Metab 2007, 32:619-634.
    • (2007) Appl Physiol Nutr Metab , vol.32 , pp. 619-634
    • Plourde, M.1    Cunnane, S.C.2
  • 3
    • 3142753961 scopus 로고    scopus 로고
    • Structure, function, and dietary regulation of delta6, delta5, and delta9 desaturases
    • Nakamura M.T., Nara T.Y. Structure, function, and dietary regulation of delta6, delta5, and delta9 desaturases. Annu Rev Nutr 2004, 24:345-376.
    • (2004) Annu Rev Nutr , vol.24 , pp. 345-376
    • Nakamura, M.T.1    Nara, T.Y.2
  • 4
    • 80455122613 scopus 로고    scopus 로고
    • Maternal alpha-linolenic acid availability during gestation and lactation alters the postnatal hippocampal development in the mouse offspring
    • Niculescu M.D., Lupu D.S., Craciunescu C.N. Maternal alpha-linolenic acid availability during gestation and lactation alters the postnatal hippocampal development in the mouse offspring. Int J Dev Neurosci 2011, 29:795-802.
    • (2011) Int J Dev Neurosci , vol.29 , pp. 795-802
    • Niculescu, M.D.1    Lupu, D.S.2    Craciunescu, C.N.3
  • 5
    • 84871898012 scopus 로고    scopus 로고
    • Perinatal manipulation of alpha-linolenic acid intake induces epigenetic changes in maternal and offspring livers
    • Niculescu M.D., Lupu D.S., Craciunescu C.N. Perinatal manipulation of alpha-linolenic acid intake induces epigenetic changes in maternal and offspring livers. FASEB J 2013, 27:350-358.
    • (2013) FASEB J , vol.27 , pp. 350-358
    • Niculescu, M.D.1    Lupu, D.S.2    Craciunescu, C.N.3
  • 6
    • 33645079134 scopus 로고    scopus 로고
    • The developmental origins of adult disease (Barker) hypothesis
    • de Boo H.A., Harding J.E. The developmental origins of adult disease (Barker) hypothesis. Aust N Z J Obstet Gynaecol 2006, 46:4-14.
    • (2006) Aust N Z J Obstet Gynaecol , vol.46 , pp. 4-14
    • de Boo, H.A.1    Harding, J.E.2
  • 7
    • 33846868388 scopus 로고    scopus 로고
    • Alpha-linolenic acid, delta6-desaturase gene polymorphism, and the risk of nonfatal myocardial infarction
    • Baylin A., Ruiz-Narvaez E., Kraft P., Campos H. Alpha-linolenic acid, delta6-desaturase gene polymorphism, and the risk of nonfatal myocardial infarction. Am J Clin Nutr 2007, 85:554-560.
    • (2007) Am J Clin Nutr , vol.85 , pp. 554-560
    • Baylin, A.1    Ruiz-Narvaez, E.2    Kraft, P.3    Campos, H.4
  • 8
    • 84878839327 scopus 로고    scopus 로고
    • Oils rich in alpha-linolenic acid independently protect against characteristics of fatty liver disease in the delta6-desaturase null mouse
    • Monteiro J., Askarian F., Nakamura M.T., Moghadasian M.H., Ma D.W. Oils rich in alpha-linolenic acid independently protect against characteristics of fatty liver disease in the delta6-desaturase null mouse. Can J Physiol Pharmacol 2013, 91:469-479.
    • (2013) Can J Physiol Pharmacol , vol.91 , pp. 469-479
    • Monteiro, J.1    Askarian, F.2    Nakamura, M.T.3    Moghadasian, M.H.4    Ma, D.W.5
  • 9
    • 84861472018 scopus 로고    scopus 로고
    • Menhaden oil, but not safflower or soybean oil, aids in restoring the polyunsaturated fatty acid profile in the novel delta-6-desaturase null mouse
    • Monteiro J., Li F.J., Maclennan M., Rabalski A., Moghadasian M.H., Nakamura M.T., et al. Menhaden oil, but not safflower or soybean oil, aids in restoring the polyunsaturated fatty acid profile in the novel delta-6-desaturase null mouse. Lipids Health Dis 2012, 11:60.
    • (2012) Lipids Health Dis , vol.11 , pp. 60
    • Monteiro, J.1    Li, F.J.2    Maclennan, M.3    Rabalski, A.4    Moghadasian, M.H.5    Nakamura, M.T.6
  • 10
    • 84858174171 scopus 로고    scopus 로고
    • Polyunsaturated fatty acid levels in blood during pregnancy, at birth and at 7 years: their associations with two common FADS2 polymorphisms
    • Steer C.D., Hibbeln J.R., Golding J., Davey Smith G. Polyunsaturated fatty acid levels in blood during pregnancy, at birth and at 7 years: their associations with two common FADS2 polymorphisms. Hum Mol Genet 2012, 21:1504-1512.
    • (2012) Hum Mol Genet , vol.21 , pp. 1504-1512
    • Steer, C.D.1    Hibbeln, J.R.2    Golding, J.3    Davey Smith, G.4
  • 11
    • 84878387779 scopus 로고    scopus 로고
    • FADS genotype and diet are important determinants of DHA status: a cross-sectional study in Danish infants
    • Harslof L.B., Larsen L.H., Ritz C., Hellgren L.I., Michaelsen K.F., Vogel U., et al. FADS genotype and diet are important determinants of DHA status: a cross-sectional study in Danish infants. Am J Clin Nutr 2013, 97:1403-1410.
    • (2013) Am J Clin Nutr , vol.97 , pp. 1403-1410
    • Harslof, L.B.1    Larsen, L.H.2    Ritz, C.3    Hellgren, L.I.4    Michaelsen, K.F.5    Vogel, U.6
  • 12
    • 55949102407 scopus 로고    scopus 로고
    • Genetic variants of the FADS1 FADS2 gene cluster are associated with altered (n-6) and (n-3) essential fatty acids in plasma and erythrocyte phospholipids in women during pregnancy and in breast milk during lactation
    • Xie L., Innis S.M. Genetic variants of the FADS1 FADS2 gene cluster are associated with altered (n-6) and (n-3) essential fatty acids in plasma and erythrocyte phospholipids in women during pregnancy and in breast milk during lactation. J Nutr 2008, 138:2222-2228.
    • (2008) J Nutr , vol.138 , pp. 2222-2228
    • Xie, L.1    Innis, S.M.2
  • 13
    • 77951941671 scopus 로고    scopus 로고
    • FADS1 FADS2 gene variants modify the association between fish intake and the docosahexaenoic acid proportions in human milk
    • Moltó-Puigmartí C., Plat J., Mensink R.P., Müller A., Jansen E., Zeegers M.P., et al. FADS1 FADS2 gene variants modify the association between fish intake and the docosahexaenoic acid proportions in human milk. Am J Clin Nutr 2010, 91:1368-1376.
    • (2010) Am J Clin Nutr , vol.91 , pp. 1368-1376
    • Moltó-Puigmartí, C.1    Plat, J.2    Mensink, R.P.3    Müller, A.4    Jansen, E.5    Zeegers, M.P.6
  • 14
    • 84908125109 scopus 로고    scopus 로고
    • Supplementation with N-3 long-chain polyunsaturated fatty acids or olive oil in men and women with renal disease induces differential changes in the DNA methylation of FADS2 and ELOVL5 in peripheral blood mononuclear cells
    • Hoile S.P., Clarke-Harris R., Huang R.C., Calder P.C., Mori T.A., Beilin L.J., et al. Supplementation with N-3 long-chain polyunsaturated fatty acids or olive oil in men and women with renal disease induces differential changes in the DNA methylation of FADS2 and ELOVL5 in peripheral blood mononuclear cells. PLoS One 2014, 9:e109896.
    • (2014) PLoS One , vol.9 , pp. e109896
    • Hoile, S.P.1    Clarke-Harris, R.2    Huang, R.C.3    Calder, P.C.4    Mori, T.A.5    Beilin, L.J.6
  • 15
    • 0030407246 scopus 로고    scopus 로고
    • Comparison of multiple-pass 24-hour recall estimates of energy intake with total energy expenditure determined by the doubly labeled water method in young children
    • Johnson R.K., Driscoll P., Goran M.I. Comparison of multiple-pass 24-hour recall estimates of energy intake with total energy expenditure determined by the doubly labeled water method in young children. J Am Diet Assoc 1996, 96:1140-1144.
    • (1996) J Am Diet Assoc , vol.96 , pp. 1140-1144
    • Johnson, R.K.1    Driscoll, P.2    Goran, M.I.3
  • 16
    • 77956997560 scopus 로고    scopus 로고
    • A systematic review of the validity of dietary assessment methods in children when compared with the method of doubly labeled water
    • Burrows T.L., Martin R.J., Collins C.E. A systematic review of the validity of dietary assessment methods in children when compared with the method of doubly labeled water. J Am Diet Assoc 2010, 110:1501-1510.
    • (2010) J Am Diet Assoc , vol.110 , pp. 1501-1510
    • Burrows, T.L.1    Martin, R.J.2    Collins, C.E.3
  • 18
    • 84984680059 scopus 로고    scopus 로고
    • Low dose flaxseed oil supplementation alters the fatty acids profile and the progression of metabolic syndrome in men without adequate medical treatment
    • Tint D., Anghel M., Lupu D.S., Fischer L.M., Niculescu M.D. Low dose flaxseed oil supplementation alters the fatty acids profile and the progression of metabolic syndrome in men without adequate medical treatment. J Nutr Disord Ther 2011, S7:1.
    • (2011) J Nutr Disord Ther , vol.S7 , pp. 1
    • Tint, D.1    Anghel, M.2    Lupu, D.S.3    Fischer, L.M.4    Niculescu, M.D.5
  • 19
    • 84883193135 scopus 로고    scopus 로고
    • Dietary intake and food sources of EPA, DPA and DHA in Australian children
    • Rahmawaty S., Charlton K., Lyons-Wall P., Meyer B.J. Dietary intake and food sources of EPA, DPA and DHA in Australian children. Lipids 2013, 869-877.
    • (2013) Lipids , pp. 869-877
    • Rahmawaty, S.1    Charlton, K.2    Lyons-Wall, P.3    Meyer, B.J.4
  • 20
    • 84857789211 scopus 로고    scopus 로고
    • Effect of different levels of docosahexaenoic acid supply on fatty acid status and linoleic and alpha-linolenic acid conversion in preterm infants
    • Sauerwald U.C., Fink M.M., Demmelmair H., Schoenaich P.V., Rauh-Pfeiffer A.A., Koletzko B. Effect of different levels of docosahexaenoic acid supply on fatty acid status and linoleic and alpha-linolenic acid conversion in preterm infants. J Pediatr Gastroenterol Nutr 2012, 54:353-363.
    • (2012) J Pediatr Gastroenterol Nutr , vol.54 , pp. 353-363
    • Sauerwald, U.C.1    Fink, M.M.2    Demmelmair, H.3    Schoenaich, P.V.4    Rauh-Pfeiffer, A.A.5    Koletzko, B.6
  • 21
    • 78149265344 scopus 로고    scopus 로고
    • Dietary intake and status of n-3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters, vegetarians, and vegans and the product-precursor ratio [corrected] of alpha-linolenic acid to long-chain n-3 polyunsaturated fatty acids: results from the EPIC-Norfolk cohort
    • Welch A.A., Shakya-Shrestha S., Lentjes M.A., Wareham N.J., Khaw K.T. Dietary intake and status of n-3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters, vegetarians, and vegans and the product-precursor ratio [corrected] of alpha-linolenic acid to long-chain n-3 polyunsaturated fatty acids: results from the EPIC-Norfolk cohort. Am J Clin Nutr 2010, 92:1040-1051.
    • (2010) Am J Clin Nutr , vol.92 , pp. 1040-1051
    • Welch, A.A.1    Shakya-Shrestha, S.2    Lentjes, M.A.3    Wareham, N.J.4    Khaw, K.T.5
  • 22
    • 82355190915 scopus 로고    scopus 로고
    • Sex-specific differences in essential fatty acid metabolism
    • Decsi T., Kennedy K. Sex-specific differences in essential fatty acid metabolism. Am J Clin Nutr 2011, 94:1914S-1919S.
    • (2011) Am J Clin Nutr , vol.94 , pp. 1914S-1919S
    • Decsi, T.1    Kennedy, K.2
  • 23
    • 84870789980 scopus 로고    scopus 로고
    • Angiotensinogen gene polymorphisms and food-intake behavior in young, normal female subjects in Japan
    • Sasaki M., Yamada K., Namba H., Yoshinaga M., Du D., Uehara Y. Angiotensinogen gene polymorphisms and food-intake behavior in young, normal female subjects in Japan. Nutrition 2013, 29:60-65.
    • (2013) Nutrition , vol.29 , pp. 60-65
    • Sasaki, M.1    Yamada, K.2    Namba, H.3    Yoshinaga, M.4    Du, D.5    Uehara, Y.6
  • 24
    • 84875922294 scopus 로고    scopus 로고
    • Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake
    • Tanaka T., Ngwa J.S., van Rooij F.J., Zillikens M.C., Wojczynski M.K., Frazier-Wood A.C., et al. Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake. Am J Clin Nutr 2013, 97:1395-1402.
    • (2013) Am J Clin Nutr , vol.97 , pp. 1395-1402
    • Tanaka, T.1    Ngwa, J.S.2    van Rooij, F.J.3    Zillikens, M.C.4    Wojczynski, M.K.5    Frazier-Wood, A.C.6
  • 26
    • 84879302084 scopus 로고    scopus 로고
    • Maternal fat intake in rats alters 20:4n-6 and 22:6n-3 status and the epigenetic regulation of Fads2 in offspring liver
    • Hoile S.P., Irvine N.A., Kelsall C.J., Sibbons C., Feunteun A., Collister A., et al. Maternal fat intake in rats alters 20:4n-6 and 22:6n-3 status and the epigenetic regulation of Fads2 in offspring liver. J Nutr Biochem 2013, 24:1213-1220.
    • (2013) J Nutr Biochem , vol.24 , pp. 1213-1220
    • Hoile, S.P.1    Irvine, N.A.2    Kelsall, C.J.3    Sibbons, C.4    Feunteun, A.5    Collister, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.