Supplementation with n-3 long-chain polyunsaturated fatty acids or olive oil in men and women with renal disease induces differential changes in the DNA methylation of FADS2 and ELOVL5 in peripheral blood mononuclear cells

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Hoile, Samuel P ^a   Clarke Harris, Rebecca ^a   Huang, Rae Chi ^b   Calder, Philip C ^a,c   Mori, Trevor A ^d   Beilin, Lawrence J ^d   Lillycrop, Karen A ^e   Burdge, Graham C ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST   (United Kingdom)

^d UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^e UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A DESATURASE 1; MESSENGER RNA; OLIVE OIL; OMEGA 3 ACID ETHYL ESTER; ACYL COENZYME A DESATURASE; ACYLTRANSFERASE; FADS2 PROTEIN, HUMAN; FATTY ACID ELONGASES; OMEGA 3 FATTY ACID; VEGETABLE OIL;

ACYL COENZYME A DESATURASE 1 GENE; ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DIET SUPPLEMENTATION; DNA METHYLATION; ELOVL 2 GENE; ELOVL 5 GENE; EPIGENETICS; FATTY ACID DESATURASE GENE; FEMALE; GENE; GENE EXPRESSION; GENE LOCUS; HUMAN; HUMAN CELL; KIDNEY DISEASE; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; SEQUENCE ANALYSIS; CHRONIC KIDNEY FAILURE; CONTROLLED CLINICAL TRIAL; DRUG EFFECTS; GENETICS; METABOLISM; MIDDLE AGED; MOLECULAR GENETICS; MONONUCLEAR CELL; NUCLEOTIDE SEQUENCE;

ACETYLTRANSFERASES; ADULT; BASE SEQUENCE; DIETARY SUPPLEMENTS; DNA METHYLATION; FATTY ACID DESATURASES; FATTY ACIDS, OMEGA-3; FEMALE; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PLANT OILS; RENAL INSUFFICIENCY, CHRONIC;

EID: 84908125109     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0109896     Document Type: Article

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