-
1
-
-
57049151909
-
Marker metabolites can be therapeutic targets as well
-
Arakaki AK, Skolnick J and McDonald JF. Marker metabolites can be therapeutic targets as well. Nature 2008; 456: 443.
-
(2008)
Nature
, vol.456
, pp. 443
-
-
Arakaki, A.K.1
Skolnick, J.2
McDonald, J.F.3
-
2
-
-
80255124795
-
Identification of serum biomarkers of hepatocarcinoma through liquid chromatography/mass spectrometry-based metabonomic method
-
Chen F, Xue J, Zhou L, Wu S and Chen Z. Identification of serum biomarkers of hepatocarcinoma through liquid chromatography/mass spectrometry-based metabonomic method. Analytical and Bioanalytical Chemistry 2011a; 401: 1899-1904.
-
(2011)
Analytical and Bioanalytical Chemistry
, vol.401
, pp. 1899-1904
-
-
Chen, F.1
Xue, J.2
Zhou, L.3
Wu, S.4
Chen, Z.5
-
3
-
-
84855206110
-
Serum and urine metabolite profiling reveals potential biomarkers of human hepatocellular carcinoma
-
Chen T, Xie G, Wang X, Fan J, Qiu Y, Zheng X, Qi X, Cao Y, Su M, Wang X, Xu LX, Yen Y, Liu P and Jia W. Serum and urine metabolite profiling reveals potential biomarkers of human hepatocellular carcinoma. Molecular and Cellular Proteomics 2011b; 10: M110.004945.
-
(2011)
Molecular and Cellular Proteomics
, vol.10
, pp. M110004945
-
-
Chen, T.1
Xie, G.2
Wang, X.3
Fan, J.4
Qiu, Y.5
Zheng, X.6
Qi, X.7
Cao, Y.8
Su, M.9
Wang, X.10
Xu, L.X.11
Yen, Y.12
Liu, P.13
Jia, W.14
-
4
-
-
79959913950
-
Human Serum Metabolome (HUSERMET) Consortium. Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry
-
Dunn WB, Broadhurst D, Begley P, Zelena E, Francis-McIntyre S, Anderson N, Brown M, Knowles JD, Halsall A, Haselden JN, Nicholls AW, Wilson ID, Kell DB and Goodacre R. Human Serum Metabolome (HUSERMET) Consortium. Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry. Nature Protocols 2011; 6: 1060-1083.
-
(2011)
Nature Protocols
, vol.6
, pp. 1060-1083
-
-
Dunn, W.B.1
Broadhurst, D.2
Begley, P.3
Zelena, E.4
Francis-McIntyre, S.5
Anderson, N.6
Brown, M.7
Knowles, J.D.8
Halsall, A.9
Haselden, J.N.10
Nicholls, A.W.11
Wilson, I.D.12
Kell, D.B.13
Goodacre, R.14
-
5
-
-
84868367130
-
Serum UPLC-MS/MS metabolic profiling in an experimental model for acute-liver injury reveals potential biomarkers for hepatotoxicity
-
Gonzalez E, van Liempd S, Conde-Vancells J, Gutierrez-de Juan V, Perez-Cormenzana M, Mayo R, Berisa A, Alonso C, Marquez CA, Barr J, Lu SC, Mato JM and Falcon-Perez JM. Serum UPLC-MS/MS metabolic profiling in an experimental model for acute-liver injury reveals potential biomarkers for hepatotoxicity. Metabolomics 2012; 8: 997-1011.
-
(2012)
Metabolomics
, vol.8
, pp. 997-1011
-
-
Gonzalez, E.1
van Liempd, S.2
Conde-Vancells, J.3
Gutierrez-de Juan, V.4
Perez-Cormenzana, M.5
Mayo, R.6
Berisa, A.7
Alonso, C.8
Marquez, C.A.9
Barr, J.10
Lu, S.C.11
Mato, J.M.12
Falcon-Perez, J.M.13
-
6
-
-
84873388502
-
Investigation of the human brain metabolome to identify potential markers for early diagnosis and therapeutic targets of Alzheimer's disease
-
Graham SF, Chevallier OP, Roberts D, Hölscher C, Elliott CT and Green BD. Investigation of the human brain metabolome to identify potential markers for early diagnosis and therapeutic targets of Alzheimer's disease. Analytical Chemistry 2013; 85: 1803-1811.
-
(2013)
Analytical Chemistry
, vol.85
, pp. 1803-1811
-
-
Graham, S.F.1
Chevallier, O.P.2
Roberts, D.3
Hölscher, C.4
Elliott, C.T.5
Green, B.D.6
-
7
-
-
43749087841
-
Human metabolic phenotype diversity and its association with diet and blood pressure
-
Holmes E, Loo RL, Stamler S, Bictash M, Yap IK, Chan Q, Ebbels T, De Iorio M, Brown IJ, Veselkov KA, Daviglus ML, Kesteloot H, Ueshima H, Zhao L, Nicholson JK and Elliott P. Human metabolic phenotype diversity and its association with diet and blood pressure. Nature 2008; 453: 396-401.
-
(2008)
Nature
, vol.453
, pp. 396-401
-
-
Holmes, E.1
Loo, R.L.2
Stamler, S.3
Bictash, M.4
Yap, I.K.5
Chan, Q.6
Ebbels, T.7
De Iorio, M.8
Brown, I.J.9
Veselkov, K.A.10
Daviglus, M.L.11
Kesteloot, H.12
Ueshima, H.13
Zhao, L.14
Nicholson, J.K.15
Elliott, P.16
-
8
-
-
80053654173
-
A metabolomic approach to lung cancer
-
Hori S, Nishiumi S, Kobayashi K, Shinohara M, Hatakeyama Y, Kotani Y, Hatano N, Maniwa Y, Nishio W, Bamba T, Fukusaki E, Azuma T, Takenawa T, Nishimura Y and Yoshida M. A metabolomic approach to lung cancer. Lung Cancer 2011; 74: 284-292.
-
(2011)
Lung Cancer
, vol.74
, pp. 284-292
-
-
Hori, S.1
Nishiumi, S.2
Kobayashi, K.3
Shinohara, M.4
Hatakeyama, Y.5
Kotani, Y.6
Hatano, N.7
Maniwa, Y.8
Nishio, W.9
Bamba, T.10
Fukusaki, E.11
Azuma, T.12
Takenawa, T.13
Nishimura, Y.14
Yoshida, M.15
-
9
-
-
84869398478
-
Toward a predictive model of Alzheimer's disease progression using capillary electrophoresis-mass spectrometry metabolomics
-
Ibáñez C, Simó C, Martín-Álvarez PJ, Kivipelto M, Winblad B, Cedazo-Mínguez A and Cifuentes A. Toward a predictive model of Alzheimer's disease progression using capillary electrophoresis-mass spectrometry metabolomics. Analytical Chemistry 2012; 84: 8532-8540.
-
(2012)
Analytical Chemistry
, vol.84
, pp. 8532-8540
-
-
Ibáñez, C.1
Simó, C.2
Martín-Álvarez, P.J.3
Kivipelto, M.4
Winblad, B.5
Cedazo-Mínguez, A.6
Cifuentes, A.7
-
11
-
-
79955766231
-
Urine molecular profiling distinguishes health and disease: new methods in diagnostics? Focus on UPLC-MS
-
König S. Urine molecular profiling distinguishes health and disease: new methods in diagnostics? Focus on UPLC-MS. Expert Reviws in Molecular Diagnosis 2011; 11: 383-391.
-
(2011)
Expert Reviws in Molecular Diagnosis
, vol.11
, pp. 383-391
-
-
König, S.1
-
12
-
-
79952436750
-
LC-MS based serum metabonomic analysis for renal cell carcinoma diagnosis, staging, and biomarker discovery
-
Lin L, Huang Z, Gao Y, Yan X, Xing J and Hang W. LC-MS based serum metabonomic analysis for renal cell carcinoma diagnosis, staging, and biomarker discovery. Journal of Proteome Research 2011; 10: 1396-1405.
-
(2011)
Journal of Proteome Research
, vol.10
, pp. 1396-1405
-
-
Lin, L.1
Huang, Z.2
Gao, Y.3
Yan, X.4
Xing, J.5
Hang, W.6
-
13
-
-
0043069547
-
Understanding 'global' systems biology: metabonomics and the continuum of metabolism
-
Nicholson JK, Wilson ID. Understanding 'global' systems biology: metabonomics and the continuum of metabolism. Nature Reviews 2003; 2: 668-676.
-
(2003)
Nature Reviews
, vol.2
, pp. 668-676
-
-
Nicholson, J.K.1
Wilson, I.D.2
-
14
-
-
84867732904
-
A pilot metabolic profiling study in serum of patients with chronic kidney disease based on (1) H-NMR-spectroscopy
-
Qi S, Ouyang X, Wang L, Peng W, Wen J and Dai Y. A pilot metabolic profiling study in serum of patients with chronic kidney disease based on (1) H-NMR-spectroscopy. Clinical and Translation Science 2012; 5: 379-385.
-
(2012)
Clinical and Translation Science
, vol.5
, pp. 379-385
-
-
Qi, S.1
Ouyang, X.2
Wang, L.3
Peng, W.4
Wen, J.5
Dai, Y.6
-
15
-
-
78650907092
-
Applications of liquid chromatography coupled to mass spectrometry-based metabolomics in clinical chemistry and toxicology: a review
-
Roux A, Lison D, Junot C and Heilier JF. Applications of liquid chromatography coupled to mass spectrometry-based metabolomics in clinical chemistry and toxicology: a review. Clinical Biochemistry 2011; 44(1): 119-135.
-
(2011)
Clinical Biochemistry
, vol.44
, Issue.1
, pp. 119-135
-
-
Roux, A.1
Lison, D.2
Junot, C.3
Heilier, J.F.4
-
16
-
-
80051623540
-
Serum metabolomics reveals γ-glutamyl dipeptides as biomarkers for discrimination among different forms of liver disease
-
Soga T, Sugimoto M, Honma M, Mori M, Igarashi K, Kashikura K, Ikeda S, Hirayama A, Yamamoto T, Yoshida H, Otsuka M, Tsuji S, Yatomi Y, Sakuragawa T, Watanabe H, Nihei K, Saito T, Kawata S, Suzuki H, Tomita M and Suematsu M. Serum metabolomics reveals γ-glutamyl dipeptides as biomarkers for discrimination among different forms of liver disease. Journal of Hepatology 2011; 55: 896-905.
-
(2011)
Journal of Hepatology
, vol.55
, pp. 896-905
-
-
Soga, T.1
Sugimoto, M.2
Honma, M.3
Mori, M.4
Igarashi, K.5
Kashikura, K.6
Ikeda, S.7
Hirayama, A.8
Yamamoto, T.9
Yoshida, H.10
Otsuka, M.11
Tsuji, S.12
Yatomi, Y.13
Sakuragawa, T.14
Watanabe, H.15
Nihei, K.16
Saito, T.17
Kawata, S.18
Suzuki, H.19
Tomita, M.20
Suematsu, M.21
more..
-
17
-
-
84874642175
-
Metabolomic analysis of key regulatory metabolites in hepatitis C virus-infected tree shrews
-
Sun H, Zhang A, Yan G, Piao C, Li W, Sun C, Wu X, Li X, Chen Y and Wang X. Metabolomic analysis of key regulatory metabolites in hepatitis C virus-infected tree shrews. Molecular and Cellular Proteomics 2013; 12: 710-719.
-
(2013)
Molecular and Cellular Proteomics
, vol.12
, pp. 710-719
-
-
Sun, H.1
Zhang, A.2
Yan, G.3
Piao, C.4
Li, W.5
Sun, C.6
Wu, X.7
Li, X.8
Chen, Y.9
Wang, X.10
-
18
-
-
84863080102
-
Metabolomics study of stepwise hepatocarcinogenesis from the model rats to patients: potential biomarkers effective for small hepatocellular carcinoma diagnosis
-
M111.010694.
-
Tan Y, Yin P, Tang L, Xing W, Huang Q, Cao D, Zhao X, Wang W, Lu X, Xu Z, Wang H and Xu G. Metabolomics study of stepwise hepatocarcinogenesis from the model rats to patients: potential biomarkers effective for small hepatocellular carcinoma diagnosis. Molecular and Cellular Proteomics 2012; 11: M111.010694.
-
(2012)
Molecular and Cellular Proteomics
, vol.11
-
-
Tan, Y.1
Yin, P.2
Tang, L.3
Xing, W.4
Huang, Q.5
Cao, D.6
Zhao, X.7
Wang, W.8
Lu, X.9
Xu, Z.10
Wang, H.11
Xu, G.12
-
19
-
-
84864309412
-
Exploration of serum metabolomic profiles and outcomes in women with metastatic breast cancer: a pilot study
-
Tenori L, Oakman C, Claudino WM, Bernini P, Cappadona S, Nepi S, Biganzoli L, Arbushites MC, Luchinat C, Bertini I and Di Leo A. Exploration of serum metabolomic profiles and outcomes in women with metastatic breast cancer: a pilot study. Molecular Oncology 2012; 6: 437-444.
-
(2012)
Molecular Oncology
, vol.6
, pp. 437-444
-
-
Tenori, L.1
Oakman, C.2
Claudino, W.M.3
Bernini, P.4
Cappadona, S.5
Nepi, S.6
Biganzoli, L.7
Arbushites, M.C.8
Luchinat, C.9
Bertini, I.10
Di Leo, A.11
-
20
-
-
84861422298
-
Cancer. Systems biology, metabolomics, and cancer metabolism
-
Tomita M, Kami K. Cancer. Systems biology, metabolomics, and cancer metabolism. Science 2012; 336: 990-991.
-
(2012)
Science
, vol.336
, pp. 990-991
-
-
Tomita, M.1
Kami, K.2
-
21
-
-
84866402322
-
Discovery of phosphatidylcholines and sphingomyelins as biomarkers for ovarian endometriosis
-
Vouk K, Hevir N, Ribić-Pucelj M, Haarpaintner G, Scherb H, Osredkar J, Möller G, Prehn C, Rižner TL and Adamski J. Discovery of phosphatidylcholines and sphingomyelins as biomarkers for ovarian endometriosis. Human Reproduction 2012; 27: 2955-2965.
-
(2012)
Human Reproduction
, vol.27
, pp. 2955-2965
-
-
Vouk, K.1
Hevir, N.2
Ribić-Pucelj, M.3
Haarpaintner, G.4
Scherb, H.5
Osredkar, J.6
Möller, G.7
Prehn, C.8
Rižner, T.L.9
Adamski, J.10
-
22
-
-
84863042105
-
Metabonomic profiles discriminate hepatocellular carcinoma from liver cirrhosis by ultraperformance liquid chromatography-mass spectrometry
-
Wang B, Chen D, Chen Y, Hu Z, Cao M, Xie Q, Chen Y, Xu J, Zheng S and Li L. Metabonomic profiles discriminate hepatocellular carcinoma from liver cirrhosis by ultraperformance liquid chromatography-mass spectrometry. Journal of Proteome Research 2012a; 11: 1217-1227.
-
(2012)
Journal of Proteome Research
, vol.11
, pp. 1217-1227
-
-
Wang, B.1
Chen, D.2
Chen, Y.3
Hu, Z.4
Cao, M.5
Xie, Q.6
Chen, Y.7
Xu, J.8
Zheng, S.9
Li, L.10
-
23
-
-
79953737332
-
Metabolite profiles and the risk of developing diabetes
-
Wang TJ, Larson MG, Vasan RS, Cheng S, Rhee EP, McCabe E, Lewis GD, Fox CS, Jacques PF, Fernandez C, O'Donnell CJ, Carr SA, Mootha VK, Florez JC, Souza A, Melander O, Clish CB and Gerszten RE. Metabolite profiles and the risk of developing diabetes. Nature Medicine 2011; 17: 448-453.
-
(2011)
Nature Medicine
, vol.17
, pp. 448-453
-
-
Wang, T.J.1
Larson, M.G.2
Vasan, R.S.3
Cheng, S.4
Rhee, E.P.5
McCabe, E.6
Lewis, G.D.7
Fox, C.S.8
Jacques, P.F.9
Fernandez, C.10
O'Donnell, C.J.11
Carr, S.A.12
Mootha, V.K.13
Florez, J.C.14
Souza, A.15
Melander, O.16
Clish, C.B.17
Gerszten, R.E.18
-
24
-
-
84855392494
-
Pattern recognition approaches and computational systems tools for ultra performance liquid chromatography-mass spectrometry-based comprehensive metabolomic profiling and pathways analysis of biological data sets
-
Wang X, Yang B, Sun H and Zhang A. Pattern recognition approaches and computational systems tools for ultra performance liquid chromatography-mass spectrometry-based comprehensive metabolomic profiling and pathways analysis of biological data sets. Analytical Chemistry 2012b; 84: 428-439.
-
(2012)
Analytical Chemistry
, vol.84
, pp. 428-439
-
-
Wang, X.1
Yang, B.2
Sun, H.3
Zhang, A.4
-
25
-
-
84864828304
-
Urine metabolomics analysis for biomarker discovery and detection of jaundice syndrome in patients with liver disease
-
Wang X, Zhang A, Han Y, Wang P, Sun H, Song G, Dong T, Yuan Y, Yuan X, Zhang M, Xie N, Zhang H, Dong H and Dong W. Urine metabolomics analysis for biomarker discovery and detection of jaundice syndrome in patients with liver disease. Molecular and Cellular Proteomics 2012c; 11: 370-380.
-
(2012)
Molecular and Cellular Proteomics
, vol.11
, pp. 370-380
-
-
Wang, X.1
Zhang, A.2
Han, Y.3
Wang, P.4
Sun, H.5
Song, G.6
Dong, T.7
Yuan, Y.8
Yuan, X.9
Zhang, M.10
Xie, N.11
Zhang, H.12
Dong, H.13
Dong, W.14
-
27
-
-
84863702568
-
A metabonomics study of epilepsy in patients using gas chromatography coupled with mass spectrometry
-
Wei C, Li Y, Yao H, Liu H, Zhang X and Guo R. A metabonomics study of epilepsy in patients using gas chromatography coupled with mass spectrometry. Molecular Biosystems 2012; 8: 2197-2204.
-
(2012)
Molecular Biosystems
, vol.8
, pp. 2197-2204
-
-
Wei, C.1
Li, Y.2
Yao, H.3
Liu, H.4
Zhang, X.5
Guo, R.6
-
28
-
-
57949103373
-
Mass spectrometry based metabolomic approaches in urinary biomarker study of women's cancers
-
Woo HM, Kim KM, Choi MH, Jung BH, Lee J, Kong G, Nam SJ, Kim S, Bai SW and Chung BC. Mass spectrometry based metabolomic approaches in urinary biomarker study of women's cancers. Clinica Chimica Acta 2009; 400: 63-69.
-
(2009)
Clinica Chimica Acta
, vol.400
, pp. 63-69
-
-
Woo, H.M.1
Kim, K.M.2
Choi, M.H.3
Jung, B.H.4
Lee, J.5
Kong, G.6
Nam, S.J.7
Kim, S.8
Bai, S.W.9
Chung, B.C.10
-
29
-
-
84870915868
-
LC-MS based serum metabolomics for identification of hepatocellular carcinoma biomarkers in Egyptian cohort
-
Xiao JF, Varghese RS, Zhou B, Nezami Ranjbar MR, Zhao Y, Tsai TH, Di Poto C, Wang J, Goerlitz D, Luo Y, Cheema AK, Sarhan N, Soliman H, Tadesse MG, Ziada DH and Ressom HW. LC-MS based serum metabolomics for identification of hepatocellular carcinoma biomarkers in Egyptian cohort. Journal of Proteome Research 2012; 11: 5914-5923.
-
(2012)
Journal of Proteome Research
, vol.11
, pp. 5914-5923
-
-
Xiao, J.F.1
Varghese, R.S.2
Zhou, B.3
Nezami Ranjbar, M.R.4
Zhao, Y.5
Tsai, T.H.6
Di Poto, C.7
Wang, J.8
Goerlitz, D.9
Luo, Y.10
Cheema, A.K.11
Sarhan, N.12
Soliman, H.13
Tadesse, M.G.14
Ziada, D.H.15
Ressom, H.W.16
-
30
-
-
84877598859
-
Global and targeted metabolomics of esophageal squamous cell carcinoma discovers potential diagnostic and therapeutic biomarkers
-
Xu J, Chen Y, Zhang R, Song Y, Cao J, Bi N, Wang J, He J, Bai J, Dong L, Wang L, Zhan Q and Abliz Z. Global and targeted metabolomics of esophageal squamous cell carcinoma discovers potential diagnostic and therapeutic biomarkers. Molecular and Cellular Proteomics 2013; 12: 1306-1318.
-
(2013)
Molecular and Cellular Proteomics
, vol.12
, pp. 1306-1318
-
-
Xu, J.1
Chen, Y.2
Zhang, R.3
Song, Y.4
Cao, J.5
Bi, N.6
Wang, J.7
He, J.8
Bai, J.9
Dong, L.10
Wang, L.11
Zhan, Q.12
Abliz, Z.13
-
31
-
-
84857626878
-
Diagnosis of gastroenterological diseases by metabolome analysis using gas chromatography-mass spectrometry
-
Yoshida M, Hatano N, Nishiumi S, Irino Y, Izumi Y, Takenawa T and Azuma T. Diagnosis of gastroenterological diseases by metabolome analysis using gas chromatography-mass spectrometry. Journal of Gastroenterology 2012; 47: 9-20.
-
(2012)
Journal of Gastroenterology
, vol.47
, pp. 9-20
-
-
Yoshida, M.1
Hatano, N.2
Nishiumi, S.3
Irino, Y.4
Izumi, Y.5
Takenawa, T.6
Azuma, T.7
-
32
-
-
84871784703
-
Saliva metabolomics opens door to biomarker discovery, disease diagnosis, and treatment
-
Zhang A, Sun H and Wang X. Saliva metabolomics opens door to biomarker discovery, disease diagnosis, and treatment. Applied Biochemistry and Biotechnology 2012a; 168: 1718-1727.
-
(2012)
Applied Biochemistry and Biotechnology
, vol.168
, pp. 1718-1727
-
-
Zhang, A.1
Sun, H.2
Wang, X.3
-
34
-
-
83455203337
-
Modern analytical techniques in metabolomics analysis
-
Zhang A, Sun H, Wang P, Han Y and Wang X. Modern analytical techniques in metabolomics analysis. Analyst 2012c; 137: 293-300.
-
(2012)
Analyst
, vol.137
, pp. 293-300
-
-
Zhang, A.1
Sun, H.2
Wang, P.3
Han, Y.4
Wang, X.5
-
35
-
-
84864989347
-
Exploratory urinary metabolic biomarkers and pathways using UPLC-Q-TOF-HDMS coupled with pattern recognition approach
-
Zhang A, Sun H, Han Y, Yuan Y, Wang P, Song G, Yuan X, Zhang M, Xie N and Wang X. Exploratory urinary metabolic biomarkers and pathways using UPLC-Q-TOF-HDMS coupled with pattern recognition approach. Analyst 2012d; 137: 4200-4208.
-
(2012)
Analyst
, vol.137
, pp. 4200-4208
-
-
Zhang, A.1
Sun, H.2
Han, Y.3
Yuan, Y.4
Wang, P.5
Song, G.6
Yuan, X.7
Zhang, M.8
Xie, N.9
Wang, X.10
-
36
-
-
84873263333
-
Metabolomics study on the hepatoprotective effect of scoparone using ultra-performance liquid chromatography/electrospray ionization quadruple time-of-flight mass spectrometry
-
Zhang A, Sun H, Dou S, Sun W, Wu X, Wang P and Wang X. Metabolomics study on the hepatoprotective effect of scoparone using ultra-performance liquid chromatography/electrospray ionization quadruple time-of-flight mass spectrometry. Analyst 2013; 138: 353-361.
-
(2013)
Analyst
, vol.138
, pp. 353-361
-
-
Zhang, A.1
Sun, H.2
Dou, S.3
Sun, W.4
Wu, X.5
Wang, P.6
Wang, X.7
-
37
-
-
84877887630
-
Metabolomics in chronic kidney diseases
-
Clinica Chimica Acta 2013
-
Zhao YY, Xu Q. Metabolomics in chronic kidney diseases. Clinica Chimica Acta 2013; pii: S0009-8981(13)00133-2. Clin Chim Acta 2013; 422: 59-69.
-
(2013)
Clin Chim Acta
, vol.422
, pp. 59-69
-
-
Zhao, Y.Y.1
Xu, Q.2
|