A metabonomics study of epilepsy in patients using gas chromatography coupled with mass spectrometry

Molecular BioSystems

Volumn 8, Issue 8, 2012, Pages 2197-2204

  Wei, Chunmin ^a,b   Li, Yi ^b   Yao, Han ^b   Liu, Huanjun ^b   Zhang, Xiumei ^a   Guo, Ruichen ^b  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; BLOOD; CHILD; EPILEPSY; HUMAN; IN VITRO STUDY; MALE; MASS FRAGMENTOGRAPHY; METABOLISM; METABOLOMICS; METHODOLOGY;

ADOLESCENT; ADULT; CHILD; EPILEPSY; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; MALE; METABOLOMICS; YOUNG ADULT;

EID: 84863702568     PISSN: 1742206X     EISSN: 17422051     Source Type: Journal    
DOI: 10.1039/c2mb25105a     Document Type: Article

References (30)

1. R. B. Aird The importance of seizure-inducing factors in the control of refractory forms of epilepsy Epilepsia 1983 24 567 583
2. K. O. Nakken M. H. Solaas M. J. Kjeldsen M. L. Friis J. M. Pellock L. A. Corey Which seizure-precipitating factors do patients with epilepsy most frequently report? Epilepsy Behav. 2005 6 85 89
3. D. R. Curtis J. C. Watkins The excitation and depression of spinal neurones by structurally related amino acids J. Neurochem. 1960 6 117 141
4. P. B. Bradley J. H. Wolstencroft Excitation and inhibition of brain-stem neurons by noradrenaline and acetylcholine Nature 1962 196 840
5. F. E. Bloom E. Costa G. C. Salmoiraghi Analysis of Individual Rabbit Olfactory Bulb Neuron Responses to the Microelectrophoresis of Acetylcholine, Norepinephrine and Serotonin Synergists and Antagonists J. Pharmacol. Exp. Ther. 1964 146 16 23
6. C. D. Ferrie S. Bird K. Tilling M. N. Maisey A. G. Chapman R. O. Robinson Plasma amino acids in childhood epileptic encephalopathies Epilepsy Res. 1999 34 221 229
7. E. Chanut B. Labarthe B. Lacroix A. Noda S. Gasdeblay J. R. Bondier C. Versaux-Botteri Variations of dopamine, serotonin, and amino acid concentrations in Noda epileptic rat (NER) retina Brain Res. 2006 1070 56 64
8. D. Steinhauser J. Kopka Methods, applications and concepts of metabolite profiling: primary metabolism EXS 2007 97 171 194
9. A. R. Fernie R. N. Trethewey A. J. Krotzky L. Willmitzer Metabolite profiling: from diagnostics to systems biology Nat. Rev. Mol. Cell Biol. 2004 5 763 769
10. J. T. Bjerrum O. H. Nielsen F. Hao H. Tang J. K. Nicholson Y. Wang J. Olsen Metabonomics in ulcerative colitis: diagnostics, biomarker identification, and insight into the pathophysiology J. Proteome Res. 2010 9 954 962
11. H. C. Bertram J. O. Duus B. O. Petersen C. Hoppe A. Larnkjaer L. Schack-Nielsen C. Molgaard K. F. Michaelsen Nuclear magnetic resonance-based metabonomics reveals strong sex effect on plasma metabolism in 17-year-old Scandinavians and correlation to retrospective infant plasma parameters Metab., Clin. Exp. 2009 58 1039 1045
12. M. M. Koek R. H. Jellema J. van der Greef A. C. Tas T. Hankemeier Quantitative metabolomics based on gas chromatography mass spectrometry: status and perspectives Metabolomics 2011 7 307 328
13. X. Li X. Luo X. Lu J. Duan G. Xu Metabolomics study of diabetic retinopathy using gas chromatography-mass spectrometry: a comparison of stages and subtypes diagnosed by Western and Chinese medicine Mol. BioSyst. 2011 7 2228 2237
14. Z. An Y. Chen R. Zhang Y. Song J. Sun J. He J. Bai L. Dong Q. Zhan Z. Abliz Integrated ionization approach for RRLC-MS/MS-based metabonomics: finding potential biomarkers for lung cancer J. Proteome Res. 2010 9 4071 4081
15. Y. Chen R. Zhang Y. Song J. He J. Sun J. Bai Z. An L. Dong Q. Zhan Z. Abliz RRLC-MS/MS-based metabonomics combined with in-depth analysis of metabolic correlation network: finding potential biomarkers for breast cancer Analyst 2009 134 2003 2011
16. X. Li Z. Xu X. Lu X. Yang P. Yin H. Kong Y. Yu G. Xu Comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry for metabonomics: Biomarker discovery for diabetes mellitus Anal. Chim. Acta 2009 633 257 262
17. Z. F. Li J. Wang C. Huang S. Zhang J. Yang A. Jiang R. Zhou D. Pan Gas chromatography/time-of-flight mass spectrometry-based metabonomics of hepatocarcinoma in rats with lung metastasis: elucidation of the metabolic characteristics of hepatocarcinoma at formation and metastasis Rapid Commun. Mass Spectrom. 2010 24 2765 2775
18. K. K. Pasikanti P. C. Ho E. C. Y. Chan Gas chromatography/mass spectrometry in metabolic profiling of biological fluids J. Chromatogr., B: Anal. Technol. Biomed. Life Sci. 2008 871 202 211
19. Y. Koh K. K. Pasikanti C. W. Yap E. C. Chan Comparative evaluation of software for retention time alignment of gas chromatography/time-of-flight mass spectrometry-based metabonomic data J. Chromatogr., A 2010 1217 8308 8316
20. L. Krall J. Huege G. Catchpole D. Steinhauser L. Willmitzer Assessment of sampling strategies for gas chromatography-mass spectrometry (GC-MS) based metabolomics of cyanobacteria J. Chromatogr., B, Anal. Technol. Biomed. Life Sci. 2009 877 2952 2960
21. A. C. Foster J. A. Kemp Glutamate- and GABA-based CNS therapeutics Curr. Opin. Pharmacol. 2006 6 7 17
22. F. Pena R. Tapia Seizures and neurodegeneration induced by 4-aminopyridine in rat hippocampus in vivo: role of glutamate- and GABA-mediated neurotransmission and of ion channels Neuroscience 2000 101 547 561
23. F. Guo F. Sun J. L. Yu Q. H. Wang D. Y. Tu X. Y. Mao R. Liu K. C. Wu N. Xie L. Y. Hao Abnormal expressions of glutamate transporters and metabotropic glutamate receptor 1 in the spontaneously epileptic rat hippocampus Brain Res. Bull. 2010 81 510 516
24. J. C. Alvarez M. Sanceaume C. Advenier O. Spreux-Varoquaux Differential changes in brain and platelet 5-HT concentration after steady state achievement and repeated administration of antidepressant drugs in mice Eur. Neuropsychopharmacol. 1999 10 31 36
25. N. J. Jovic D. Mirkovic N. Majkic-Singh D. D. Milovanovic Plasma and urinary serotonin and 5-HIAA in children treated with lamotrigine for intractable epilepsy Adv. Exp. Med. Biol. 1999 467 297 302
26. D. C. Chugani Serotonin in autism and pediatric epilepsies Mental Retardation Dev. Disabilities Res. Rev. 2004 10 112 116
27. J. L. Haines S. S. Rich M. Tsai V. E. Anderson Altered amino acids levels in multiply affected sibships with seizures Epilepsia 1985 26 642 648
28. N. Strehmel J. Hummel A. Erban K. Strassburg J. Kopka Retention index thresholds for compound matching in GC-MS metabolite profiling J. Chromatogr., B: Anal. Technol. Biomed. Life Sci. 2008 871 182 190
29. H. Lu W. B. Dunn H. Shen D. B. Kell Y. Liang Comparative evaluation of software for deconvolution of metabolomics data based on GC-TOF-MS Trends Anal. Chem. 2008 27 215 227
30. Z. Ramadan D. Jacobs M. Grigorov S. Kochhar Metabolic profiling using principal component analysis, discriminant partial least squares, and genetic algorithms Talanta 2006 68 1683 1691