-
1
-
-
84883466306
-
A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors
-
M. Aragona, T. Panciera, A. Manfrin, S. Giulitti, F. Michielin, N. Elvassore, S. Dupont, and S. Piccolo A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors Cell 154 2013 1047 1059
-
(2013)
Cell
, vol.154
, pp. 1047-1059
-
-
Aragona, M.1
Panciera, T.2
Manfrin, A.3
Giulitti, S.4
Michielin, F.5
Elvassore, N.6
Dupont, S.7
Piccolo, S.8
-
2
-
-
84891012505
-
Switch enhancers interpret TGF-β and Hippo signaling to control cell fate in human embryonic stem cells
-
T.A. Beyer, A. Weiss, Y. Khomchuk, K. Huang, A.A. Ogunjimi, X. Varelas, and J.L. Wrana Switch enhancers interpret TGF-β and Hippo signaling to control cell fate in human embryonic stem cells Cell Rep. 5 2013 1611 1624
-
(2013)
Cell Rep.
, vol.5
, pp. 1611-1624
-
-
Beyer, T.A.1
Weiss, A.2
Khomchuk, Y.3
Huang, K.4
Ogunjimi, A.A.5
Varelas, X.6
Wrana, J.L.7
-
3
-
-
34249018367
-
GEFs and GAPs: Critical elements in the control of small G proteins
-
J.L. Bos, H. Rehmann, and A. Wittinghofer GEFs and GAPs: critical elements in the control of small G proteins Cell 129 2007 865 877
-
(2007)
Cell
, vol.129
, pp. 865-877
-
-
Bos, J.L.1
Rehmann, H.2
Wittinghofer, A.3
-
4
-
-
0842281652
-
Rho and Rac take center stage
-
K. Burridge, and K. Wennerberg Rho and Rac take center stage Cell 116 2004 167 179
-
(2004)
Cell
, vol.116
, pp. 167-179
-
-
Burridge, K.1
Wennerberg, K.2
-
5
-
-
0035941212
-
AKAP-Lbc anchors protein kinase A and nucleates Galpha 12-selective Rho-mediated stress fiber formation
-
D. Diviani, J. Soderling, and J.D. Scott AKAP-Lbc anchors protein kinase A and nucleates Galpha 12-selective Rho-mediated stress fiber formation J. Biol. Chem. 276 2001 44247 44257
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 44247-44257
-
-
Diviani, D.1
Soderling, J.2
Scott, J.D.3
-
6
-
-
33745014962
-
AKAP-Lbc: A molecular scaffold for the integration of cyclic AMP and Rho transduction pathways
-
D. Diviani, L. Baisamy, and A. Appert-Collin AKAP-Lbc: a molecular scaffold for the integration of cyclic AMP and Rho transduction pathways Eur. J. Cell Biol. 85 2006 603 610
-
(2006)
Eur. J. Cell Biol.
, vol.85
, pp. 603-610
-
-
Diviani, D.1
Baisamy, L.2
Appert-Collin, A.3
-
7
-
-
79958284636
-
Role of YAP/TAZ in mechanotransduction
-
S. Dupont, L. Morsut, M. Aragona, E. Enzo, S. Giulitti, M. Cordenonsi, F. Zanconato, J. Le Digabel, M. Forcato, S. Bicciato, and et al. Role of YAP/TAZ in mechanotransduction Nature 474 2011 179 183
-
(2011)
Nature
, vol.474
, pp. 179-183
-
-
Dupont, S.1
Morsut, L.2
Aragona, M.3
Enzo, E.4
Giulitti, S.5
Cordenonsi, M.6
Zanconato, F.7
Le Digabel, J.8
Forcato, M.9
Bicciato, S.10
-
8
-
-
79956327002
-
Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila
-
B.G. Fernández, P. Gaspar, C. Brás-Pereira, B. Jezowska, S.R. Rebelo, and F. Janody Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila Development 138 2011 2337 2346
-
(2011)
Development
, vol.138
, pp. 2337-2346
-
-
Fernández, B.G.1
Gaspar, P.2
Brás-Pereira, C.3
Jezowska, B.4
Rebelo, S.R.5
Janody, F.6
-
9
-
-
24344486013
-
RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis
-
A. Hakem, O. Sanchez-Sweatman, A. You-Ten, G. Duncan, A. Wakeham, R. Khokha, and T.W. Mak RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis Genes Dev. 19 2005 1974 1979
-
(2005)
Genes Dev.
, vol.19
, pp. 1974-1979
-
-
Hakem, A.1
Sanchez-Sweatman, O.2
You-Ten, A.3
Duncan, G.4
Wakeham, A.5
Khokha, R.6
Mak, T.W.7
-
10
-
-
84920989984
-
Long-term culture of genome-stable bipotent stem cells from adult human liver
-
M. Huch, H. Gehart, R. van Boxtel, K. Hamer, F. Blokzijl, M.M. Verstegen, E. Ellis, M. van Wenum, S.A. Fuchs, J. de Ligt, and et al. Long-term culture of genome-stable bipotent stem cells from adult human liver Cell 160 2015 299 312
-
(2015)
Cell
, vol.160
, pp. 299-312
-
-
Huch, M.1
Gehart, H.2
Van Boxtel, R.3
Hamer, K.4
Blokzijl, F.5
Verstegen, M.M.6
Ellis, E.7
Van Wenum, M.8
Fuchs, S.A.9
De Ligt, J.10
-
11
-
-
0033571243
-
Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: Comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases
-
A.K. Indra, X. Warot, J. Brocard, J.M. Bornert, J.H. Xiao, P. Chambon, and D. Metzger Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases Nucleic Acids Res. 27 1999 4324 4327
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 4324-4327
-
-
Indra, A.K.1
Warot, X.2
Brocard, J.3
Bornert, J.M.4
Xiao, J.H.5
Chambon, P.6
Metzger, D.7
-
12
-
-
79953310106
-
Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF
-
D. Lai, K.C. Ho, Y. Hao, and X. Yang Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF Cancer Res. 71 2011 2728 2738
-
(2011)
Cancer Res.
, vol.71
, pp. 2728-2738
-
-
Lai, D.1
Ho, K.C.2
Hao, Y.3
Yang, X.4
-
13
-
-
77953040994
-
The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation
-
I. Lian, J. Kim, H. Okazawa, J. Zhao, B. Zhao, J. Yu, A. Chinnaiyan, M.A. Israel, L.S. Goldstein, R. Abujarour, and et al. The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation Genes Dev. 24 2010 1106 1118
-
(2010)
Genes Dev.
, vol.24
, pp. 1106-1118
-
-
Lian, I.1
Kim, J.2
Okazawa, H.3
Zhao, J.4
Zhao, B.5
Yu, J.6
Chinnaiyan, A.7
Israel, M.A.8
Goldstein, L.S.9
Abujarour, R.10
-
14
-
-
84880017102
-
The Hippo pathway polarizes the actin cytoskeleton during collective migration of Drosophila border cells
-
E.P. Lucas, I. Khanal, P. Gaspar, G.C. Fletcher, C. Polesello, N. Tapon, and B.J. Thompson The Hippo pathway polarizes the actin cytoskeleton during collective migration of Drosophila border cells J. Cell Biol. 201 2013 875 885
-
(2013)
J. Cell Biol.
, vol.201
, pp. 875-885
-
-
Lucas, E.P.1
Khanal, I.2
Gaspar, P.3
Fletcher, G.C.4
Polesello, C.5
Tapon, N.6
Thompson, B.J.7
-
15
-
-
77950638532
-
The Rho guanine nucleotide exchange factor AKAP13 (BRX) is essential for cardiac development in mice
-
C.M. Mayers, J. Wadell, K. McLean, M. Venere, M. Malik, T. Shibata, P.H. Driggers, T. Kino, X.C. Guo, H. Koide, and et al. The Rho guanine nucleotide exchange factor AKAP13 (BRX) is essential for cardiac development in mice J. Biol. Chem. 285 2010 12344 12354
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 12344-12354
-
-
Mayers, C.M.1
Wadell, J.2
McLean, K.3
Venere, M.4
Malik, M.5
Shibata, T.6
Driggers, P.H.7
Kino, T.8
Guo, X.C.9
Koide, H.10
-
16
-
-
84891345748
-
A genetic screen identifies an LKB1-MARK signalling axis controlling the Hippo-YAP pathway
-
M. Mohseni, J. Sun, A. Lau, S. Curtis, J. Goldsmith, V.L. Fox, C. Wei, M. Frazier, O. Samson, K.K. Wong, and et al. A genetic screen identifies an LKB1-MARK signalling axis controlling the Hippo-YAP pathway Nat. Cell Biol. 16 2014 108 117
-
(2014)
Nat. Cell Biol.
, vol.16
, pp. 108-117
-
-
Mohseni, M.1
Sun, J.2
Lau, A.3
Curtis, S.4
Goldsmith, J.5
Fox, V.L.6
Wei, C.7
Frazier, M.8
Samson, O.9
Wong, K.K.10
-
17
-
-
0025315642
-
Immunochemical identification of the ADP-ribosyltransferase in botulinum C1 neurotoxin as C3 exoenzyme-like molecule
-
N. Morii, Y. Ohashi, Y. Nemoto, M. Fujiwara, Y. Ohnishi, T. Nishiki, Y. Kamata, S. Kozaki, S. Narumiya, and G. Sakaguchi Immunochemical identification of the ADP-ribosyltransferase in botulinum C1 neurotoxin as C3 exoenzyme-like molecule J. Biochem. 107 1990 769 775
-
(1990)
J. Biochem.
, vol.107
, pp. 769-775
-
-
Morii, N.1
Ohashi, Y.2
Nemoto, Y.3
Fujiwara, M.4
Ohnishi, Y.5
Nishiki, T.6
Kamata, Y.7
Kozaki, S.8
Narumiya, S.9
Sakaguchi, G.10
-
18
-
-
84929089950
-
Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice
-
Y. Morikawa, M. Zhang, T. Heallen, J. Leach, G. Tao, Y. Xiao, Y. Bai, W. Li, J.T. Willerson, and J.F. Martin Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice Sci. Signal. 8 2015 ra41
-
(2015)
Sci. Signal.
, vol.8
, pp. ra41
-
-
Morikawa, Y.1
Zhang, M.2
Heallen, T.3
Leach, J.4
Tao, G.5
Xiao, Y.6
Bai, Y.7
Li, W.8
Willerson, J.T.9
Martin, J.F.10
-
19
-
-
39349106325
-
Differentiation of embryonic stem cells to clinically relevant populations: Lessons from embryonic development
-
C.E. Murry, and G. Keller Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development Cell 132 2008 661 680
-
(2008)
Cell
, vol.132
, pp. 661-680
-
-
Murry, C.E.1
Keller, G.2
-
21
-
-
77956243773
-
Molecular pathway and cell state responsible for dissociation-induced apoptosis in human pluripotent stem cells
-
M. Ohgushi, M. Matsumura, M. Eiraku, K. Murakami, T. Aramaki, A. Nishiyama, K. Muguruma, T. Nakano, H. Suga, M. Ueno, and et al. Molecular pathway and cell state responsible for dissociation-induced apoptosis in human pluripotent stem cells Cell Stem Cell 7 2010 225 239
-
(2010)
Cell Stem Cell
, vol.7
, pp. 225-239
-
-
Ohgushi, M.1
Matsumura, M.2
Eiraku, M.3
Murakami, K.4
Aramaki, T.5
Nishiyama, A.6
Muguruma, K.7
Nakano, T.8
Suga, H.9
Ueno, M.10
-
22
-
-
84874817493
-
An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells
-
K. Okita, T. Yamakawa, Y. Matsumura, Y. Sato, N. Amano, A. Watanabe, N. Goshima, and S. Yamanaka An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells Stem Cells 31 2013 458 466
-
(2013)
Stem Cells
, vol.31
, pp. 458-466
-
-
Okita, K.1
Yamakawa, T.2
Matsumura, Y.3
Sato, Y.4
Amano, N.5
Watanabe, A.6
Goshima, N.7
Yamanaka, S.8
-
23
-
-
0031283446
-
Distinct roles for DH and PH domains in the Lbc oncogene
-
M.F. Olson, P. Sterpetti, K. Nagata, D. Toksoz, and A. Hall Distinct roles for DH and PH domains in the Lbc oncogene Oncogene 15 1997 2827 2831
-
(1997)
Oncogene
, vol.15
, pp. 2827-2831
-
-
Olson, M.F.1
Sterpetti, P.2
Nagata, K.3
Toksoz, D.4
Hall, A.5
-
24
-
-
84929315796
-
YAP is essential for tissue tension to ensure vertebrate 3D body shape
-
S. Porazinski, H. Wang, Y. Asaoka, M. Behrndt, T. Miyamoto, H. Morita, S. Hata, T. Sasaki, S.F. Krens, Y. Osada, and et al. YAP is essential for tissue tension to ensure vertebrate 3D body shape Nature 521 2015 217 221
-
(2015)
Nature
, vol.521
, pp. 217-221
-
-
Porazinski, S.1
Wang, H.2
Asaoka, Y.3
Behrndt, M.4
Miyamoto, T.5
Morita, H.6
Hata, S.7
Sasaki, T.8
Krens, S.F.9
Osada, Y.10
-
25
-
-
84859235472
-
Transcriptional analysis of pluripotency reveals the Hippo pathway as a barrier to reprogramming
-
H. Qin, K. Blaschke, G. Wei, Y. Ohi, L. Blouin, Z. Qi, J. Yu, R.F. Yeh, M. Hebrok, and M. Ramalho-Santos Transcriptional analysis of pluripotency reveals the Hippo pathway as a barrier to reprogramming Hum. Mol. Genet. 21 2012 2054 2067
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 2054-2067
-
-
Qin, H.1
Blaschke, K.2
Wei, G.3
Ohi, Y.4
Blouin, L.5
Qi, Z.6
Yu, J.7
Yeh, R.F.8
Hebrok, M.9
Ramalho-Santos, M.10
-
26
-
-
13444252631
-
GEF means go: Turning on RHO GTPases with guanine nucleotide-exchange factors
-
K.L. Rossman, C.J. Der, and J. Sondek GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors Nat. Rev. Mol. Cell Biol. 6 2005 167 180
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 167-180
-
-
Rossman, K.L.1
Der, C.J.2
Sondek, J.3
-
27
-
-
0038013875
-
Senescence, apoptosis and therapy-cutting the lifelines of cancer
-
C.A. Schmitt Senescence, apoptosis and therapy-cutting the lifelines of cancer Nat. Rev. Cancer 3 2003 286 295
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 286-295
-
-
Schmitt, C.A.1
-
28
-
-
0038100185
-
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
-
K. Takahashi, K. Mitsui, and S. Yamanaka Role of ERas in promoting tumour-like properties in mouse embryonic stem cells Nature 423 2003 541 545
-
(2003)
Nature
, vol.423
, pp. 541-545
-
-
Takahashi, K.1
Mitsui, K.2
Yamanaka, S.3
-
30
-
-
46049087598
-
TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal
-
X. Varelas, R. Sakuma, P. Samavarchi-Tehrani, R. Peerani, B.M. Rao, J. Dembowy, M.B. Yaffe, P.W. Zandstra, and J.L. Wrana TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal Nat. Cell Biol. 10 2008 837 848
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 837-848
-
-
Varelas, X.1
Sakuma, R.2
Samavarchi-Tehrani, P.3
Peerani, R.4
Rao, B.M.5
Dembowy, J.6
Yaffe, M.B.7
Zandstra, P.W.8
Wrana, J.L.9
-
31
-
-
80051923057
-
Hippo pathway regulation by cell morphology and stress fibers
-
K. Wada, K. Itoga, T. Okano, S. Yonemura, and H. Sasaki Hippo pathway regulation by cell morphology and stress fibers Development 138 2011 3907 3914
-
(2011)
Development
, vol.138
, pp. 3907-3914
-
-
Wada, K.1
Itoga, K.2
Okano, T.3
Yonemura, S.4
Sasaki, H.5
-
32
-
-
84931268960
-
Cloning and variation of ground state intestinal stem cells
-
X. Wang, Y. Yamamoto, L.H. Wilson, T. Zhang, B.E. Howitt, M.A. Farrow, F. Kern, G. Ning, Y. Hong, C.C. Khor, and et al. Cloning and variation of ground state intestinal stem cells Nature 522 2015 173 178
-
(2015)
Nature
, vol.522
, pp. 173-178
-
-
Wang, X.1
Yamamoto, Y.2
Wilson, L.H.3
Zhang, T.4
Howitt, B.E.5
Farrow, M.A.6
Kern, F.7
Ning, G.8
Hong, Y.9
Khor, C.C.10
-
33
-
-
34250206996
-
A ROCK inhibitor permits survival of dissociated human embryonic stem cells
-
K. Watanabe, M. Ueno, D. Kamiya, A. Nishiyama, M. Matsumura, T. Wataya, J.B. Takahashi, S. Nishikawa, S. Nishikawa, K. Muguruma, and Y. Sasai A ROCK inhibitor permits survival of dissociated human embryonic stem cells Nat. Biotechnol. 25 2007 681 686
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 681-686
-
-
Watanabe, K.1
Ueno, M.2
Kamiya, D.3
Nishiyama, A.4
Matsumura, M.5
Wataya, T.6
Takahashi, J.B.7
Nishikawa, S.8
Nishikawa, S.9
Muguruma, K.10
Sasai, Y.11
-
34
-
-
84874257648
-
The Hippo pathway: Regulators and regulations
-
F.X. Yu, and K.L. Guan The Hippo pathway: regulators and regulations Genes Dev. 27 2013 355 371
-
(2013)
Genes Dev.
, vol.27
, pp. 355-371
-
-
Yu, F.X.1
Guan, K.L.2
-
35
-
-
77950866324
-
Zscan4 regulates telomere elongation and genomic stability in ES cells
-
M. Zalzman, G. Falco, L.V. Sharova, A. Nishiyama, M. Thomas, S.L. Lee, C.A. Stagg, H.G. Hoang, H.T. Yang, F.E. Indig, and et al. Zscan4 regulates telomere elongation and genomic stability in ES cells Nature 464 2010 858 863
-
(2010)
Nature
, vol.464
, pp. 858-863
-
-
Zalzman, M.1
Falco, G.2
Sharova, L.V.3
Nishiyama, A.4
Thomas, M.5
Lee, S.L.6
Stagg, C.A.7
Hoang, H.G.8
Yang, H.T.9
Indig, F.E.10
-
36
-
-
47549095853
-
TEAD mediates YAP-dependent gene induction and growth control
-
B. Zhao, X. Ye, J. Yu, L. Li, W. Li, S. Li, J. Yu, J.D. Lin, C.Y. Wang, A.M. Chinnaiyan, and et al. TEAD mediates YAP-dependent gene induction and growth control Genes Dev. 22 2008 1962 1971
-
(2008)
Genes Dev.
, vol.22
, pp. 1962-1971
-
-
Zhao, B.1
Ye, X.2
Yu, J.3
Li, L.4
Li, W.5
Li, S.6
Yu, J.7
Lin, J.D.8
Wang, C.Y.9
Chinnaiyan, A.M.10
-
37
-
-
84855326431
-
Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis
-
B. Zhao, L. Li, L. Wang, C.Y. Wang, J. Yu, and K.L. Guan Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis Genes Dev. 26 2012 54 68
-
(2012)
Genes Dev.
, vol.26
, pp. 54-68
-
-
Zhao, B.1
Li, L.2
Wang, L.3
Wang, C.Y.4
Yu, J.5
Guan, K.L.6
-
38
-
-
0028967665
-
Direct involvement of the small GTP-binding protein Rho in lbc oncogene function
-
Y. Zheng, M.F. Olson, A. Hall, R.A. Cerione, and D. Toksoz Direcvolvement of the small GTP-binding protein Rho in lbc oncogene function J. Biol. Chem. 270 1995 9031 9034
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 9031-9034
-
-
Zheng, Y.1
Olson, M.F.2
Hall, A.3
Cerione, R.A.4
Toksoz, D.5
|