Proteomic and Lipidomic Analysis of Nanoparticle Corona upon Contact with Lung Surfactant Reveals Differences in Protein, but Not Lipid Composition

ACS Nano

Volumn 9, Issue 12, 2015, Pages 11872-11885

  Raesch, Simon Sebastian ^a,b   Tenzer, Stefan ^c   Storck, Wiebke ^c   Rurainski, Alexander ^a   Selzer, Dominik ^a   Ruge, Christian Arnold ^a   Perez Gil, Jesus ^d   Schaefer, Ulrich Friedrich ^a   Lehr, Claus Michael ^a,b  

^a SAARLAND UNIVERSITY   (Germany)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

^d UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

biological barrier; bionano interface; bronchoalveolar lining fluid; inhalation; lipid protein interaction; magnetic separation; nanoparticle surface

Indexed keywords

BIOLOGICAL ORGANS; MAGNETIC SEPARATION; MOLECULAR BIOLOGY; NANOMAGNETICS; NANOPARTICLES; PHOSPHOLIPIDS; SURFACE ACTIVE AGENTS; SURFACE PROPERTIES;

BIO-NANO INTERFACES; BIOLOGICAL BARRIER; INHALATION; LIPID-PROTEIN INTERACTIONS; NANOPARTICLE SURFACE;

PROTEINS;

LUNG SURFACTANT; NANOPARTICLE; PHOSPHOLIPID; PROTEIN; PROTEIN CORONA;

BRONCHOALVEOLAR LAVAGE FLUID; CHEMISTRY; METABOLISM;

BRONCHOALVEOLAR LAVAGE FLUID; NANOPARTICLES; PHOSPHOLIPIDS; PROTEIN CORONA; PROTEINS; PULMONARY SURFACTANTS;

EID: 84952362033     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.5b04215     Document Type: Article

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