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Volumn 8, Issue 11, 2014, Pages 11778-11789

Critical determinants of uptake and translocation of nanoparticles by the human pulmonary alveolar Epithelium

Author keywords

Endocytosis; Epithelial; Human; Lung; Nanoparticles; siRNA; Surfactant

Indexed keywords

BIOLOGICAL ORGANS; CONTROLLED DRUG DELIVERY; CYTOLOGY; MOLECULAR BIOLOGY; NANOPARTICLES; NANOSTRUCTURED MATERIALS; SURFACE ACTIVE AGENTS; TARGETED DRUG DELIVERY;

EID: 84912571932     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn505399e     Document Type: Article
Times cited : (124)

References (56)
  • 1
    • 84934299031 scopus 로고    scopus 로고
    • The Woodrow Wilson International Center for Scholars (accessed Oct 26, 2014)
    • The Project on Emerging Nanotechnologies: Consumer Product Inventory. The Woodrow Wilson International Center for Scholars. 2014. http://www.nanotechproject.org/cpi (accessed Oct 26, 2014).
    • (2014) The Project on Emerging Nanotechnologies: Consumer Product Inventory
  • 5
    • 84885190174 scopus 로고    scopus 로고
    • New Perspectives in Nanomedicine
    • Thorley, A. J.; Tetley, T. D. New Perspectives in Nanomedicine. Pharmacol. Ther. 2013, 140, 176-185.
    • (2013) Pharmacol. Ther. , vol.140 , pp. 176-185
    • Thorley, A.J.1    Tetley, T.D.2
  • 6
    • 20644449754 scopus 로고    scopus 로고
    • Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles
    • Oberdorster, G.; Oberdorster, E.; Oberdorster, J. Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles. Environ. Health Perspect. 2005, 113, 823-839.
    • (2005) Environ. Health Perspect. , vol.113 , pp. 823-839
    • Oberdorster, G.1    Oberdorster, E.2    Oberdorster, J.3
  • 8
    • 0038041946 scopus 로고    scopus 로고
    • Alveolar Type I Cells: Molecular Phenotype and Development
    • Williams, M. C. Alveolar Type I Cells: Molecular Phenotype and Development. Annu. Rev. Physiol. 2003, 65, 669-695.
    • (2003) Annu. Rev. Physiol. , vol.65 , pp. 669-695
    • Williams, M.C.1
  • 10
    • 0025307779 scopus 로고
    • Surfactant Displaces Particles toward the Epithelium in Airways and Alveoli
    • Schurch, S.; Gehr, P.; Im Hof, V.; Geiser, M.; Green, F. Surfactant Displaces Particles toward the Epithelium in Airways and Alveoli. Respir. Physiol. 1990, 80, 17-32.
    • (1990) Respir. Physiol. , vol.80 , pp. 17-32
    • Schurch, S.1    Gehr, P.2    Im Hof, V.3    Geiser, M.4    Green, F.5
  • 12
    • 0032777287 scopus 로고    scopus 로고
    • Surfactant Lipid Uptake and Metabolism by Neonatal and Adult Type II Pneumocytes
    • Griese, M.; Beck, J.; Feuerhake, F. Surfactant Lipid Uptake and Metabolism by Neonatal and Adult Type II Pneumocytes. Am. J. Physiol. Lung Cell Mol. Physiol. 1999, 277, L901-L909.
    • (1999) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.277 , pp. L901-L909
    • Griese, M.1    Beck, J.2    Feuerhake, F.3
  • 16
    • 80052870945 scopus 로고    scopus 로고
    • Effects of Transport Inhibitors on the Cellular Uptake of Carboxylated Polystyrene Nanoparticles in Different Cell Lines
    • dos Santos, T.; Varela, J.; Lynch, I.; Salvati, A.; Dawson, K. A. Effects of Transport Inhibitors on the Cellular Uptake of Carboxylated Polystyrene Nanoparticles in Different Cell Lines. PLoS One 2011, 6, e24438.
    • (2011) PLoS One , vol.6 , pp. e24438
    • Dos Santos, T.1    Varela, J.2    Lynch, I.3    Salvati, A.4    Dawson, K.A.5
  • 20
    • 84866517033 scopus 로고    scopus 로고
    • Quantifying Size-Dependent Interactions between Fluorescently Labeled Polystyrene Nanoparticles and Mammalian Cells
    • Varela, J. A.; Bexiga, M. G.; Aberg, C.; Simpson, J. C.; Dawson, K. A. Quantifying Size-Dependent Interactions between Fluorescently Labeled Polystyrene Nanoparticles and Mammalian Cells. J. Nanobiotechnol. 2012, 10, 39.
    • (2012) J. Nanobiotechnol. , vol.10 , pp. 39
    • Varela, J.A.1    Bexiga, M.G.2    Aberg, C.3    Simpson, J.C.4    Dawson, K.A.5
  • 21
    • 84856813853 scopus 로고    scopus 로고
    • Identifying and Localizing Intracellular Nanoparticles Using Raman Spectroscopy
    • Dorney, J.; Bonnier, F.; Garcia, A.; Casey, A.; Chambers, G.; Byrne, H. J. Identifying and Localizing Intracellular Nanoparticles Using Raman Spectroscopy. Analyst 2012, 137, 1111-1119.
    • (2012) Analyst , vol.137 , pp. 1111-1119
    • Dorney, J.1    Bonnier, F.2    Garcia, A.3    Casey, A.4    Chambers, G.5    Byrne, H.J.6
  • 22
    • 77951637960 scopus 로고    scopus 로고
    • Assessment of Cell Line Models of Primary Human Cells by Raman Spectral Phenotyping
    • Swain, R. J.; Kemp, S. J.; Goldstraw, P.; Tetley, T. D.; Stevens, M. M. Assessment of Cell Line Models of Primary Human Cells by Raman Spectral Phenotyping. Biophys. J. 2010, 98, 1703-1711.
    • (2010) Biophys. J. , vol.98 , pp. 1703-1711
    • Swain, R.J.1    Kemp, S.J.2    Goldstraw, P.3    Tetley, T.D.4    Stevens, M.M.5
  • 23
    • 79960305949 scopus 로고    scopus 로고
    • Innate Immune Responses to Bacterial Ligands in the Peripheral Human Lung - Role of Alveolar Epithelial TLR Expression and Signalling
    • Thorley, A. J.; Grandolfo, D.; Lim, E.; Goldstraw, P.; Young, A.; Tetley, T. D. Innate Immune Responses to Bacterial Ligands in the Peripheral Human Lung - Role of Alveolar Epithelial TLR Expression and Signalling. PLoS One 2011, 6, e21827.
    • (2011) PLoS One , vol.6 , pp. e21827
    • Thorley, A.J.1    Grandolfo, D.2    Lim, E.3    Goldstraw, P.4    Young, A.5    Tetley, T.D.6
  • 25
    • 28444442646 scopus 로고    scopus 로고
    • Oxide Nanoparticle Uptake in Human Lung Fibroblasts: Effects of Particle Size, Agglomeration, and Diffusion at Low Concentrations
    • Limbach, L. K.; Li, Y.; Grass, R. N.; Brunner, T. J.; Hintermann, M. A.; Muller, M.; Gunther, D.; Stark, W. J. Oxide Nanoparticle Uptake in Human Lung Fibroblasts: Effects of Particle Size, Agglomeration, and Diffusion at Low Concentrations. Environ. Sci. Technol. 2005, 39, 9370-9376.
    • (2005) Environ. Sci. Technol. , vol.39 , pp. 9370-9376
    • Limbach, L.K.1    Li, Y.2    Grass, R.N.3    Brunner, T.J.4    Hintermann, M.A.5    Muller, M.6    Gunther, D.7    Stark, W.J.8
  • 27
    • 68549095935 scopus 로고    scopus 로고
    • Tissue Distribution of 20nm, 100nm and 1000nm Fluorescent Polystyrene Latex Nanospheres Following Acute Systemic or Acute and Repeat Airway Exposure in the Rat
    • Sarlo, K.; Blackburn, K. L.; Clark, E. D.; Grothaus, J.; Chaney, J.; Neu, S.; Flood, J.; Abbott, D.; Bohne, C.; Casey, K.; et al. Tissue Distribution of 20nm, 100nm and 1000nm Fluorescent Polystyrene Latex Nanospheres Following Acute Systemic or Acute and Repeat Airway Exposure in the Rat. Toxicology 2009, 263, 117-126.
    • (2009) Toxicology , vol.263 , pp. 117-126
    • Sarlo, K.1    Blackburn, K.L.2    Clark, E.D.3    Grothaus, J.4    Chaney, J.5    Neu, S.6    Flood, J.7    Abbott, D.8    Bohne, C.9    Casey, K.10
  • 29
    • 68649109575 scopus 로고    scopus 로고
    • Translocation Pathway of the Intratracheally Instilled C60 Fullerene from the Lung into the Blood Circulation in the Mouse: Possible Association of Diffusion and Caveolae-mediated Pinocytosis
    • Naota, M.; Shimada, A.; Morita, T.; Inoue, K.; Takano, H. Translocation Pathway of the Intratracheally Instilled C60 Fullerene from the Lung into the Blood Circulation in the Mouse: Possible Association of Diffusion and Caveolae-mediated Pinocytosis. Toxicol. Pathol. 2009, 37, 456-462.
    • (2009) Toxicol. Pathol. , vol.37 , pp. 456-462
    • Naota, M.1    Shimada, A.2    Morita, T.3    Inoue, K.4    Takano, H.5
  • 31
    • 77952482571 scopus 로고    scopus 로고
    • Technosphere Insulin: An Inhaled Prandial Insulin Product
    • Neumiller, J. J.; Campbell, R. K. Technosphere Insulin: An Inhaled Prandial Insulin Product. BioDrugs 2010, 24, 165-172.
    • (2010) BioDrugs , vol.24 , pp. 165-172
    • Neumiller, J.J.1    Campbell, R.K.2
  • 32
    • 42649099670 scopus 로고    scopus 로고
    • Cationic Polystyrene Nanosphere Toxicity Depends on Cell-Specific Endocytic and Mitochondrial Injury Pathways
    • Xia, T.; Kovochich, M.; Liong, M.; Zink, J. I.; Nel, A. E. Cationic Polystyrene Nanosphere Toxicity Depends on Cell-Specific Endocytic and Mitochondrial Injury Pathways. ACS Nano 2008, 2, 85-96.
    • (2008) ACS Nano , vol.2 , pp. 85-96
    • Xia, T.1    Kovochich, M.2    Liong, M.3    Zink, J.I.4    Nel, A.E.5
  • 37
    • 0028247215 scopus 로고
    • Effect of Endocytosis Inhibitors on Alveolar Clearance of Albumin, Immunoglobulin G, and SP-A in Rabbits
    • Hastings, R. H.; Wright, J. R.; Albertine, K. H.; Ciriales, R.; Matthay, M. A. Effect of Endocytosis Inhibitors on Alveolar Clearance of Albumin, Immunoglobulin G, and SP-A in Rabbits. Am. J. Physiol. 1994, 266, L544-552.
    • (1994) Am. J. Physiol. , vol.266 , pp. L544-L552
    • Hastings, R.H.1    Wright, J.R.2    Albertine, K.H.3    Ciriales, R.4    Matthay, M.A.5
  • 41
    • 84861329967 scopus 로고    scopus 로고
    • Pulmonary Surfactant Coating of Multi-Walled Carbon Nanotubes (MWCNTs) Influences their Oxidative and Pro-Inflammatory Potential In Vitro
    • Gasser, M.; Wick, P.; Clift, M. J.; Blank, F.; Diener, L.; Yan, B.; Gehr, P.; Krug, H. F.; Rothen-Rutishauser, B. Pulmonary Surfactant Coating of Multi-Walled Carbon Nanotubes (MWCNTs) Influences their Oxidative and Pro-Inflammatory Potential In Vitro. Part. Fibre Toxicol. 2012, 9, 17.
    • (2012) Part. Fibre Toxicol. , vol.9 , pp. 17
    • Gasser, M.1    Wick, P.2    Clift, M.J.3    Blank, F.4    Diener, L.5    Yan, B.6    Gehr, P.7    Krug, H.F.8    Rothen-Rutishauser, B.9
  • 43
    • 84856599417 scopus 로고    scopus 로고
    • Cellular Uptake Mechanism and Knockdown Activity of siRNA-Loaded Biodegradable DEAPA-PVA-g-PLGA Nanoparticles
    • Benfer, M.; Kissel, T. Cellular Uptake Mechanism and Knockdown Activity of siRNA-Loaded Biodegradable DEAPA-PVA-g-PLGA Nanoparticles. Eur. J. Pharm. Biopharm. 2012, 80, 247-256.
    • (2012) Eur. J. Pharm. Biopharm. , vol.80 , pp. 247-256
    • Benfer, M.1    Kissel, T.2
  • 49
  • 50
    • 33746047516 scopus 로고    scopus 로고
    • Human Pulmonary Surfactant Protein D Binds the Extracellular Domains of Toll-like Receptors 2 and 4 Through the Carbohydrate Recognition Domain by a Mechanism Different from its Binding to Phosphatidylinositol and Lipopolysaccharide
    • Ohya, M.; Nishitani, C.; Sano, H.; Yamada, C.; Mitsuzawa, H.; Shimizu, T.; Saito, T.; Smith, K.; Crouch, E.; Kuroki, Y. Human Pulmonary Surfactant Protein D Binds the Extracellular Domains of Toll-like Receptors 2 and 4 Through the Carbohydrate Recognition Domain by a Mechanism Different from its Binding to Phosphatidylinositol and Lipopolysaccharide. Biochemistry 2006, 45, 8657-8664.
    • (2006) Biochemistry , vol.45 , pp. 8657-8664
    • Ohya, M.1    Nishitani, C.2    Sano, H.3    Yamada, C.4    Mitsuzawa, H.5    Shimizu, T.6    Saito, T.7    Smith, K.8    Crouch, E.9    Kuroki, Y.10
  • 52
    • 0142053191 scopus 로고    scopus 로고
    • Isolation and Culture of Human Alveolar Type II Pneumocytes
    • Rogers, D. F., Donnelly, L. D., Ed.; Humana Press: Totowa
    • Witherden, I. R.; Tetley, T. D. Isolation and Culture of Human Alveolar Type II Pneumocytes. In Human Airway Inflammation; Sampling Techniques and Analytical Protocols; Rogers, D. F., Donnelly, L. D., Ed.; Humana Press: Totowa, 2001; pp 137-146.
    • (2001) Human Airway Inflammation; Sampling Techniques and Analytical Protocols , pp. 137-146
    • Witherden, I.R.1    Tetley, T.D.2
  • 54
    • 84873273831 scopus 로고    scopus 로고
    • Deciphering the Mechanisms of Cellular Uptake of Engineered Nanoparticles by Accurate Evaluation of Internalization Using Imaging Flow Cytometry
    • Vranic, S.; Boggetto, N.; Contremoulins, V.; Mornet, S.; Reinhardt, N.; Marano, F.; Baeza-Squiban, A.; Boland, S. Deciphering the Mechanisms of Cellular Uptake of Engineered Nanoparticles by Accurate Evaluation of Internalization Using Imaging Flow Cytometry. Part. Fibre Toxicol. 2013, 10, 2.
    • (2013) Part. Fibre Toxicol. , vol.10 , pp. 2
    • Vranic, S.1    Boggetto, N.2    Contremoulins, V.3    Mornet, S.4    Reinhardt, N.5    Marano, F.6    Baeza-Squiban, A.7    Boland, S.8
  • 55
    • 84897987661 scopus 로고    scopus 로고
    • Amphiphilic Biodegradable PEG-PCL-PEI Triblock Copolymers for FRET-Capable In Vitro and In Vivo Delivery of siRNA and Quantum Dots
    • Endres, T.; Zheng, M.; Klc¸, A.; Turowska, A.; Beck-Broichsitter, M.; Renz, H.; Merkel, O. M.; Kissel, T. Amphiphilic Biodegradable PEG-PCL-PEI Triblock Copolymers for FRET-Capable In Vitro and In Vivo Delivery of siRNA and Quantum Dots. Mol. Pharmaceutics 2014, 11, 1273-1281.
    • (2014) Mol. Pharmaceutics , vol.11 , pp. 1273-1281
    • Endres, T.1    Zheng, M.2    Klc¸, A.3    Turowska, A.4    Beck-Broichsitter, M.5    Renz, H.6    Merkel, O.M.7    Kissel, T.8
  • 56
    • 55749091647 scopus 로고    scopus 로고
    • Nanoparticle Size and Surface Properties Determine the Protein Corona with Possible Implications for Biological Impacts
    • Lundqvist, M.; Stigler, J.; Elia, G.; Lynch, I.; Cedervall, T.; Dawson, K. A. Nanoparticle Size and Surface Properties Determine the Protein Corona with Possible Implications for Biological Impacts. Proc. Natl. Acad. Sci. U.S.A. 2008, 105, 14265-14270.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 14265-14270
    • Lundqvist, M.1    Stigler, J.2    Elia, G.3    Lynch, I.4    Cedervall, T.5    Dawson, K.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.