Regulatory mechanisms of surfactant secretion

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1408, Issue 2-3, 1998, Pages 226-240

  Mason, Robert J ^a,b   Voelker, Dennis R ^a,b,c  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

Alveolar type II cell; Dipalmitoylphosphatidylcholine; Exocytosis; SP A; SP B; SP C; SP D; Surfactant protein

Indexed keywords

CELL SURFACE RECEPTOR; DIPALMITOYLPHOSPHATIDYLCHOLINE; LUNG SURFACTANT; SURFACTANT PROTEIN A;

CELL MEMBRANE; HUMAN; HYPERVENTILATION; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN METABOLISM; PROTEIN SECRETION; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION;

1,2-DIPALMITOYLPHOSPHATIDYLCHOLINE; ANIMALS; EXOCYTOSIS; GLYCOPROTEINS; LUNG; MODELS, BIOLOGICAL; PROTEIN BINDING; PROTEOLIPIDS; PULMONARY ALVEOLI; PULMONARY SURFACTANTS; RATS; RECEPTORS, CELL SURFACE;

EID: 0031772526     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4439(98)00070-2     Document Type: Review

References (99)

1. Chander A., Fisher A.B. Regulation of lung surfactant secretion. Am. J. Physiol. 258:1990;L241-L253.
2. Creuwels L.A.J.M., van Golde L.M.G., Haagsman H.P. The pulmonary surfactant system: biochemical and clinical aspects. Lung. 175:1997;1-39.
3. Wright J.R., Dobbs L.G. Regulation of pulmonary surfactant secretion and clearance. Annu. Rev. Physiol. 53:1991;395-414.
4. Wirtz H., Schmidt M. Ventilation and secretion of pulmonary surfactant. Clin. Invest. 70:1992;3-13.
5. R.J. Mason, Surfactant secretion, in: B. Robertson, L.M.G. Van Golde, J.J. Batenburg (Eds.), Pulmonary Surfactant: From Molecular Biology to Clinical Practice, Elsevier, Amsterdam, 1992, pp. 295-312.
6. Williams M.C. Freeze-fracture studies of tubular myelin and lamellar bodies in fetal and adult rat lungs. J. Ultrastruct. Res. 64:1978;352-361.
7. Gibson K.F., Widnell C.C. The relationship between lamellar bodies and lysosomes in type II pneumocytes. Am. J. Respir. Cell Mol. Biol. 4:1991;504-513.
8. Coalson J.J., Winter V.T., Martin H.M., King R.J. Colloidal gold immunoultrastructural localization of rat surfactant. Am. Rev. Respir. Dis. 133:1986;230-237.
9. Power J.H., Barr H.A., Nicholas T.E. Surfactant-associated 15- and 35-kDa proteins are concentrated in different organelles in rat lung tissue. Exp. Lung. Res. 14:1988;209-224.
10. Oosterlaken-Dijksterhuis M.A., van Eijk M., van Buel B.L., van Golde L.M., Haagsman H.P. Surfactant protein composition of lamellar bodies isolated from rat lung. Biochem. J. 274:1991;115-119.
11. Froh D., Ballard P.L., Williams M.C., Gonzales J., Goerke J., Odom M.W., Gonzales L.W. Lamellar bodies of cultured human fetal lung: content of surfactant protein A (SP-A), surface film formation and structural transformation in vitro. Biochim. Biophys. Acta. 1052:1990;78-79.
12. Froh D., Gonzales L.W., Ballard P. Secretion of surfactant protein A and phosphatidylcholine from type II cells of human fetal lung. Am. J. Respir. Cell Mol. Biol. 8:1993;556-561.
13. Rooney S.A., Gobran L.I., Umstead T.M., Phelps D.S. Secretion of surfactant protein A from rat type II pneumocytes. Am. J. Physiol. 265:1993;L586-L590.
14. Ikegami M., Jobe A.H. Surfactant metabolism. Semin. Perinatol. 4:1993;233-240.
15. 2u-purinergic receptor. Am. J. Respir. Cell Mol. Biol. 12:1995;27-32.
16. Gobran L., Xu Z., Lu Z., Rooney S.A. P2u purinoceptor stimulation of surfactant secretion coupled to phosphatidylcholine hydrolysis in type II cells. Am. J. Physiol. 267:1994;L625-L633.
17. Sano K., Voelker D.R., Mason R.J. Effect of secretagogues on cytoplasmic free calcium in alveolar type II epithelial cells. Am. J. Physiol. 253:1987;C679-C686.
18. 2-purinoceptor regulation of surfactant phosphatidylcholine secretion. Relative roles of calcium and protein kinase C. Biochem. J. 266:1990;407-413.
19. Edwards Y.S., Power J.H.T., Nicholas T.E., Murray A.W. Effect of secretagogues on protein kinase-C (PKC) and mitogen-activated protein kinase (MAPK)-regulated pathways in rat alveolar type II cells. Am. J. Resp. Crit. Care Med. 155:1997;A211A.
20. Tsilibary E.C., Williams M.C. Actin and secretion of surfactant. J. Histochem. Cytochem. 31:1983;1298-1304.
21. Brown L.S., Pasquale S.M., Longmore W.J. Role of microtubules in surfactant secretion. J. Appl. Physiol. 58:1985;1866-1873.
22. Liu L., Wang M., Fisher A.B., Zimmerman U.-J.P. Involvement of annexin II in exocytosis of lamellar bodies from alveolar epithelial type II cells. Am. J. Physiol. 270:1996;L668-L676.
23. Sen N., Spitzer A.R., Chander A. Calcium-dependence of synexin binding may determine aggregation and fusion of lamellar bodies. Biochem. J. 15:1997;103-109.
24. Bhandari V., Lu H., Pachter J., Kresch M.J. Actin depolymerization is developmentally regulated in rat type II cells exposed to terbutaline. Pediatr. Res. 41:1997;166-171.
25. 2+-dependent exocytosis. Genes Cells. 1:1996;615-632.
26. Morgan A. Exocytosis. Essays Biochem. 30:1995;77-95.
27. Wright J.R., Clements J.A. Metabolism and turnover of lung surfactant. Am. Rev. Respir. Dis. 135:1987;426.
28. Wright J.R. Clearance and recycling of pulmonary surfactant. Am. J. Physiol. 259:1990;L1-L12.
29. Power J.H.T., Jones M.E., Barr H.A., Nicholas T.E. Analysis of pulmonary phospholipid compartments during prolonged periods of hyperpnea. Exp. Lung Res. 11:1986;105-128.
30. Nicholas T.E., Power J.H., Barr H.A. Surfactant homeostasis in the rat lung during swimming exercise. J. Appl. Physiol. 53:1982;314-324.
31. Power J.H.T., Barr H.A., Jones M.E., Nicholas T.E. Changes in surfactant pools after a physiological increase in alveolar surfactant. Am. J. Physiol. 63:1987;1902-1911.
32. Nicholas T.E., Barr H.A. The release of surfactant in rat lung by brief periods of hyperventilation. Respir. Physiol. 52:1983;69-83.
33. Faridy E.E. Effect of distension on release of surfactant in excised dogs' lungs. Respir. Physiol. 27:1976;99-114.
34. Oyarzun M.J., Clements J.A. Control of lung surfactant by ventilation, adrenergic mediators, and prostaglandins in the rabbit. Am. Rev. Respir. Dis. 117:1978;879-891.
35. Oyarzun M.J., Clements J.A. Ventilatory and cholinergic control of pulmonary surfactant in the rabbit. J. Appl. Physiol. 43:1977;39-45.
36. Massaro G.D., Massaro D. Morphologic evidence that large inflations of the lung stimulate secretion of surfactant. Am. Rev. Respir. Dis. 127:1983;235-236.
37. Nicholas T.E., Power J.H.T., Barr H.A. The pulmonary consequences of a deep breath. Respir. Physiol. 49:1982;315-324.
38. Nicholas T.E., Barr H.A. Control of release of surfactant phospholipids in the isolated perfused rat lung. J. Appl. Physiol. 51:1981;90-98.
39. Wirtz H.R.W., Dobbs L.G. Calcium mobilization and exocytosis after one mechanical stretch of lung epithelial cells. Science. 250:1990;1266-1269.
40. Sano K., Voelker D.R., Mason R.J. Tetradecanoylphorbol acetate and terbutaline stimulate surfactant secretion in alveolar type II cells without changing the membrane potential. Biochim. Biophys. Acta. 902:1987;317-326.
41. Chander A. Regulation of lung surfactant secretion by intracellular pH. Am. J. Physiol. 257:1989;L354-L360.
42. Gerboth G.D., Effros R.M., Roman R.J., Jacobs E.R. pH-induced calcium transients in type II alveolar epithelial cells. Am. J. Physiol. 264:1993;L448-L457.
43. Oguchi K., Ikegami M., Jacobs H., Jobe A. Clearance of large amounts of natural surfactants and liposomes of dipalmitoylphosphatidylcholine from the lungs of rabbits. Exp. Lung Res. 9:1985;221-235.
44. Oetomo S.B., Lewis J., Ikegami M., Jobe A.H. Surfactant treatments alter endogenous surfactant metabolism in rabbit lungs. Am. J. Physiol. 68:1990;1590-1596.
45. Pettenazzo A., Ikegami M., Seidner S., Jobe A. Clearance of surfactant phosphatidylcholine from adult rabbit lungs. J. Appl. Physiol. 64:1988;120-127.
46. Brown L.A., Longmore W.J. Adrenergic and cholinergic regulation of lung surfactant secretion in the isolated perfused rat lung and in the alveolar type II cell in culture. J. Biol. Chem. 256:1981;66-72.
47. Rice W.R., Osterhoudt K.C., Whitsett J.A. Effect of cytochalasins on surfactant release from alveolar type II cells. Biochim. Biophys. Acta. 805:1984;12-18.
48. Dobbs L.G., Mason R.J. Stimulation of secretion of disaturated phosphatidylcholine from isolated alveolar type II cells by 12-O-tetradecanoyl-13-phorbol acetate. Am. Rev. Respir. Dis. 118:1978;705-733.
49. Mettler N.R., Gray M.E., Schuffman S., LeQuire V.S. β-Adrenergic induced synthesis and secretion of phosphatidylcholine by isolated pulmonary alveolar type II cells. Lab. Invest. 45:1981;575-586.
50. Dobbs L.G., Gonzalez R.F., Marinari L.A., Mescher E.J., Hawgood S. The role of calcium in the secretion of surfactant by rat alveolar type II cells. Biochim. Biophys. Acta. 877:1986;305-313.
51. Sano K., Voelker D.R., Mason R.J. Involvement of protein kinase C in pulmonary surfactant secretion from alveolar type II cells. J. Biol. Chem. 260:1985;12725-12729.
52. Dobbs L.G., Mason R.J., Williams M.C., Benson B.J., Sueishi K. Secretion of surfactant by primary cultures of alveolar type II cells isolated from rats. Biochim. Biophys. Acta. 713:1982;118-127.
53. Mescher E.J., Dobbs L.G., Mason R.J. Cholera toxin stimulates secretion of saturated phosphatidylcholine and increases cellular cyclic AMP in isolated rat alveolar type II cells. Exp. Lung Res. 5:1983;173-182.
54. Dobbs L.G., Mason R.J. Pulmonary alveolar type II cells isolated from rats. Release of phosphatidylcholine in response to beta-adrenergic stimulation. J. Clin. Invest. 63:1979;378-387.
55. Mak J.C., Nishikawa M., Haddad E.B., Kwon O.J., Hirst S.J., Twort C.H., Barnes P.J. Localisation and expression of beta-adrenoceptor subtype mRNAs in human lung. Eur. J. Pharmacol. 302:1996;215-221.
56. Fabisiak J.P., Vessell E.S., Rannels D.E. Interactions of beta adrenergic antagonists with isolated rat alveolar type II pneumocytes. I. Analysis, characterization and regulation of specific beta adrenergic receptors. J. Pharmacol. Exp. Ther. 241:1987;722-727.
57. Gilfillan A.M., Rooney S.A. Purinoceptor agonists stimulate phosphatidylcholine secretion in primary culture of adult rat type II pneumocytes. Biochim. Biophys. Acta. 917:1987;18-23.
58. Rice W.R., Singleton F.M. P2-purinoceptors regulate surfactant secretion from rat isolated alveolar type II cells. Br. J. Pharmacol. 89:1986;485-491.
59. Rice W.R., Singleton F.M. P2Y-purinoceptor regulation of surfactant secretion from rat isolated alveolar type II cells is associated with mobilization of intracellular calcium. Br. J. Pharmacol. 91:1987;833-838.
60. Warburton D., Buckley S., Cosico L. P1 and P2 purinergic receptor signal transduction in rat type II pneumocytes. J. Appl. Physiol. 66:1989;901-905.
61. Tio D., Tayag A., Rehn M., Warburton D. Role of inositol triphosphate isomer formation in type II pneumocyte signal transduction. Am. J. Respir. Cell Mol. Biol. 4:1991;514-518.
62. Chander A., Sen N., Wu A.-M., Spitzer A.R. Protein kinase C in ATP regulation of lung surfactant secretion in type II cells. Am. J. Physiol. 268:1995;L108-L116.
63. Griese M., Gobran L.I., Douglas J.S., Rooney S.A. Adenosine A2-receptor-mediated phosphatidylcholine secretion in type II pneumocytes. Am. J. Physiol. 260:1991;L52-L60.
64. 1 receptor-mediated inhibition of surfactant secretion in rat type II pneumocytes. Am. J. Physiol. 258:1990;L45-L51.
65. Rice W.F., Burhans M., Wispe J.R. Effect of oxygen exposure on ATP content of rat bronchoalveolar lavage. Pediatr. Res. 25:1989;396-398.
66. Pian M.S., Dobbs L.G., Duzgunes N. Positive correlation between cytosolic free calcium and surfactant secretion in cultured rat alveolar type II cells. Biochim. Biophys. Acta. 960:1988;43-53.
67. Gilfillan A.M., Rooney S.A. Arachidonic acid metabolites stimulate phosphatidylcholine secretion in primary cultures of type II pneumocytes. Biochim. Biophys. Acta. 833:1985;336-341.
68. Gilfillan A.M., Rooney S.A. Leukotrienes stimulate phosphatidylcholine secretion in cultured type II pneumocytes. Biochim. Biophys. Acta. 876:1986;22-27.
69. Baybutt R.C., Smith J.E., Gillespie M.N., Newcomb T.G., Yeh Y.-Y. Arachidonic acid and eicosapentaenoic acid stimulate type II pneumocyte surfactant secretion. Lipids. 29:1994;535-539.
70. Cott G.R., Westcott J.Y., Voelkel N.F. Prostaglandin and leukotriene production by alveolar type II cells in vitro. Am. J. Physiol. 258:1990;L179-L187.
71. Brown L.A., Wood L.H. Stimulation of surfactant secretion by vasopressin in primary cultures of adult rat type II pneumocytes. Biochim. Biophys. Acta. 1001:1989;76-81.
72. Sen N., Grunstein M.M., Chander A. Stimulation of lung surfactant secretion by endothelin-1 from rat alveolar type II cells. Am. J. Physiol. 266:1994;L255-L262.
73. Pian M.S., Dobbs L.G. Lipoprotein-stimulated surfactant secretion in alveolar type II cells: mediation by heterotrimeric G proteins. Am. J. Physiol. 273:1997;L634-L639.
74. Voyno-Yasenetskaya T.A., Dobbs L.G., Erickson S.K., Hamilton R.L. Low density lipoprotein- and high density lipoprotein-mediated signal transduction and exocytosis in alveolar type II cells. Proc. Natl. Acad. Sci. USA. 90:1993;4256-4260.
75. Rice W.R., Singleton F.M. Regulation of surfactant phospholipid secretion from isolated rat alveolar type II cells by lectins. Biochim. Biophys. Acta. 958:1988;205-210.
76. Hildebran J.N., Goerke J., Clements J.A. Pulmonary surface film stability and composition. J. Appl. Physiol. 47:1979;604-611.
77. Dobbs L.G., Wright J.R., Hawgood S., Gonzalez R., Venstrom K., Nellenbogen J. Pulmonary surfactant and its components inhibit secretion of phosphatidylcholine from cultured rat alveolar type II cells. Proc. Natl. Acad. Sci. USA. 84:1987;1010-1014.
78. Rice W.R., Ross G.F., Singleton F.M., Dingle S., Whitsett J.A. Surfactant-associated protein inhibits phospholipid secretion from type II cells. J. Appl. Physiol. 63:1987;692-698.
79. Kuroki Y., Mason R.J., Voelker D.R. Chemical modification of surfactant protein A alters high affinity binding to rat alveolar type II cells and regulation of phospholipid secretion. J. Biol. Chem. 263:1988;17596-17602.
80. Kuroki Y., Mason R.J., Voelker D.R. Pulmonary surfactant apoprotein A structure and modulation of surfactant secretion by rat alveolar type II cells. J. Biol. Chem. 263:1988;3388-3394.
81. Kuroki Y., Mason R.J., Voelker D.R. Alveolar type II cells express a high-affinity receptor for pulmonary surfactant protein A. Proc. Natl. Acad. Sci. USA. 85:1988;5566-5570.
82. Wright J.R., Borchelt J.D., Hawgood S. Lung surfactant apoprotein SP-A (26-36 kDa) binds with high affinity to isolated alveolar type II cells. Proc. Natl. Acad. Sci. USA. 86:1989;5410-5414.
83. Wright J.R. Immunomodulatory functions of surfactant. Physiol. Rev. 77:1997;931-962.
84. Honma T., Kuroki Y., Tsunezawa W., Ogasawara Y., Sohma H., Voelker D.R., Akino T. The mannose binding protein A region of Glu 185-Ala 221 can functionally replace the surfactant protein A region of Glu 195-Phe 228 without loss of interaction with lipids and alveolar type II cells. Biochemistry. 36:1997;7176-7184.
85. Sano H., Kuroki Y., Honma T., Ogaswara Y., Sohma H., Voelker D.R., Akino T. Analysis of chimeric proteins identifies the regions in the carbohydrate recognition domains of rat lung collectins that are essential for interactions with phospholipids, glycolipids, and alveolar type II cells. J. Biol. Chem. 273:1998;4783-4789.
86. Kalina M., Socher R. Internalization of pulmonary surfactant into lamellar bodies of cultured rat pulmonary type II cells. J. Histochem. Cytochem. 38:1990;483-492.
87. Chroneos Z.C., Abdolrasulnia R., Whitsett J.A., Rice W.R., Shepherd V.L. Purification of a cell-surface receptor for surfactant protein A. J. Biol. Chem. 271:1996;16375-16383.
88. Strayer D.S., Pinder R., Chander A. Receptor-mediated regulation of pulmonary surfactant secretion. Exp. Cell Res. 226:1996;90-97.
89. Nepomuceno R.R., Henschen-Edman A.H., Burgess W.H., Tenner A.J. cDNA cloning and primary structure analysis of C1qRp, the human C1q/MBL/SPA receptor that mediates enhanced phagocytosis in vitro. Immunity. 6:1997;119-129.
90. Wissel H., Looman A.C., Fritzsche I., Rustow B., Stevens P.A. SP-A-binding protein BP55 is involved in surfactant endocytosis by type II pneumocytes. Am. J. Physiol. 271:1996;L432-L440.
91. Suwabe A., Mason R.J., Voelker D.R. Temporal segregation of surfactant secretion and lamellar body biogenesis in primary cultures of rat alveolar type II cells. Am. J. Respir. Cell Mol. Biol. 5:1991;80-86.
92. Dranoff G., Crawford A.D., Sadelain M., Ream B., Rashid A., Bronson R.T., Dickersin G.R., Bachurski C.J., Mark E.L., Whitsett J.A., Mulligan R.C. Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis. Science. 264:1994;713-716.
93. Saitoh H., Okayama H., Fushimi T., Shimura S., Shirato K., Hosoda K. Surfactant protein-A secretion and genotype in human airway submucosal glands. Am. J. Resp. Crit. Care Med. 155:1997;A210.
94. Korfhagen T.R., Bruno M.D., Ross G.F., Huelsman K.M., Ikegami M., Jobe A.H., Wert S.E., Stripp B.E., Morris R.E., Glasser S.W., Bachurski C.J., Iwamoto H.S., Whitsett J.A. Altered surfactant function and structure in SP-A gene target mice. Proc. Natl. Acad. Sci. USA. 93:1996;9594-9599.
95. Ikegami M., Korfhagen T.R., Bruno M.D., Whitsett J.A., Jobe A.H. Surfactant metabolism in surfactant protein A-deficient mice. Am. J. Physiol. 272:1997;L479-L485.
96. McCormack F.X., Calvert H.M., Watson P.A., Smith D.L., Mason R.J., Voelker D.R. The structure and function of surfactant protein A: hydroxyproline and carbohydrate-deficient mutant proteins. J. Biol. Chem. 269:1994;5833-5841.
97. 6 intermolecular disulfide bond and the collagen-like region of rat SP-A play critical roles in interactions with alveolar type II cells and surfactant lipids. J. Biol. Chem. 272:1997;27971-27979.
98. 197 are essential for receptor binding, phospholipid aggregation, regulation of secretion, and the facilitated uptake of phospholipid by type II cells. J. Biol. Chem. 269:1994;29801-29807.
99. McCormack F.X., Stewart J., Voelker D.R., Damodarasamy M. Alanine mutagenesis of surfactant protein A reveals that lipid binding and pH-dependent liposome aggregation are mediated by the carbohydrate recognition domain. Biochemistry. 36:1997;13963-13971.