Quantitative assessment of nanoparticle surface hydrophobicity and its influence on pulmonary biocompatibility

Journal of Controlled Release

Volumn 183, Issue 1, 2014, Pages 94-104

  Jones, Marie Christine ^a   Jones, Stuart A ^a   Riffo Vasquez, Yanira ^a   Spina, Domenico ^a   Hoffman, Ewelina ^a   Morgan, Anna ^a   Patel, Aateka ^a   Page, Clive ^a   Forbes, Ben ^a   Dailey, Lea Ann ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Hydrophobicity; Lipid nanocapsules; Nanomedicine; Nanotoxicology; Polystyrene; Pulmonary drug delivery

Indexed keywords

BIOCOMPATIBILITY; BODY FLUIDS; HYBRID INTEGRATED CIRCUITS; HYDROPHOBIC CHROMATOGRAPHY; HYDROPHOBICITY; LIQUID CHROMATOGRAPHY; MAMMALS; MEDICAL NANOTECHNOLOGY; NANOCAPSULES; NANOPARTICLES; NANOSTRUCTURED MATERIALS; PATHOLOGY; POLYSTYRENES; POLYVINYL ACETATES; RESPIRATORY THERAPY;

HYDROPHOBIC INTERACTION CHROMATOGRAPHY; LIPID NANOCAPSULES; NANOTOXICOLOGY; POLYSTYRENE NANOPARTICLES; POLYVINYL ACETATES (PVAC); PRO-INFLAMMATORY CYTOKINES; PULMONARY ADMINISTRATIONS; PULMONARY DRUG DELIVERY;

DRUG DELIVERY;

CLCX 1 PROTEIN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 1BETA; INTERLEUKIN 6; NANOPARTICLE; POLYSTYRENE; POLYVINYL ACETATE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; BIOMATERIAL; DRUG CARRIER; LIPID; POLYSTYRENE DERIVATIVE; POLYVINYL DERIVATIVE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BIOCOMPATIBILITY; CELL VACUOLE; CONTROLLED STUDY; HISTOPATHOLOGY; HYDROPHILICITY; HYDROPHOBIC INTERACTION CHROMATOGRAPHY; HYDROPHOBICITY; LUNG; MACROPHAGE; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PHENOTYPE; PNEUMONIA; PRIORITY JOURNAL; PROTEIN CONTENT; SURFACE CHARGE; SURFACE PROPERTY; TISSUE INJURY; ZETA POTENTIAL; ANIMAL; APOPTOSIS; BAGG ALBINO MOUSE; CELL LINE; CHEMICAL PHENOMENA; CHEMICALLY INDUCED; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; IMMUNOLOGY; INHALATIONAL DRUG ADMINISTRATION; LIQUID CHROMATOGRAPHY; LUNG LAVAGE; PARTICLE SIZE; PATHOLOGY; PROCEDURES; TOXICITY;

ADMINISTRATION, INHALATION; ANIMALS; APOPTOSIS; BIOCOMPATIBLE MATERIALS; BRONCHOALVEOLAR LAVAGE FLUID; CELL LINE; CHROMATOGRAPHY, LIQUID; CYTOKINES; DRUG CARRIERS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIPIDS; LUNG; MALE; MICE, INBRED BALB C; NANOPARTICLES; PARTICLE SIZE; PNEUMONIA; POLYSTYRENES; POLYVINYLS; SURFACE PROPERTIES;

EID: 84898648696     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.03.022     Document Type: Article

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