-
1
-
-
84874086395
-
Beyond secondary structure: primary-sequence determinants license pri-miRNA hairpins for processing
-
Auyeung V.C., Ulitsky I., McGeary S.E., Bartel D.P. Beyond secondary structure: primary-sequence determinants license pri-miRNA hairpins for processing. Cell 2013, 152:844-858.
-
(2013)
Cell
, vol.152
, pp. 844-858
-
-
Auyeung, V.C.1
Ulitsky, I.2
McGeary, S.E.3
Bartel, D.P.4
-
2
-
-
70350442963
-
Coupled RNA processing and transcription of intergenic primary microRNAs
-
Ballarino M., Pagano F., Girardi E., Morlando M., Cacchiarelli D., Marchioni M., Proudfoot N.J., Bozzoni I. Coupled RNA processing and transcription of intergenic primary microRNAs. Mol. Cell. Biol. 2009, 29:5632-5638.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 5632-5638
-
-
Ballarino, M.1
Pagano, F.2
Girardi, E.3
Morlando, M.4
Cacchiarelli, D.5
Marchioni, M.6
Proudfoot, N.J.7
Bozzoni, I.8
-
3
-
-
58249088751
-
MicroRNAs: target recognition and regulatory functions
-
Bartel D.P. MicroRNAs: target recognition and regulatory functions. Cell 2009, 136:215-233.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
4
-
-
84874113985
-
A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility
-
Bassik M.C., Kampmann M., Lebbink R.J., Wang S., Hein M.Y., Poser I., Weibezahn J., Horlbeck M.A., Chen S., Mann M., et al. A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility. Cell 2013, 152:909-922.
-
(2013)
Cell
, vol.152
, pp. 909-922
-
-
Bassik, M.C.1
Kampmann, M.2
Lebbink, R.J.3
Wang, S.4
Hein, M.Y.5
Poser, I.6
Weibezahn, J.7
Horlbeck, M.A.8
Chen, S.9
Mann, M.10
-
5
-
-
22844440427
-
Identification of hundreds of conserved and nonconserved human microRNAs
-
Bentwich I., Avniel A., Karov Y., Aharonov R., Gilad S., Barad O., Barzilai A., Einat P., Einav U., Meiri E., et al. Identification of hundreds of conserved and nonconserved human microRNAs. Nat. Genet. 2005, 37:766-770.
-
(2005)
Nat. Genet.
, vol.37
, pp. 766-770
-
-
Bentwich, I.1
Avniel, A.2
Karov, Y.3
Aharonov, R.4
Gilad, S.5
Barad, O.6
Barzilai, A.7
Einat, P.8
Einav, U.9
Meiri, E.10
-
6
-
-
9144224451
-
Processing of primary microRNAs by the Microprocessor complex
-
Denli A.M., Tops B.B., Plasterk R.H., Ketting R.F., Hannon G.J. Processing of primary microRNAs by the Microprocessor complex. Nature 2004, 432:231-235.
-
(2004)
Nature
, vol.432
, pp. 231-235
-
-
Denli, A.M.1
Tops, B.B.2
Plasterk, R.H.3
Ketting, R.F.4
Hannon, G.J.5
-
7
-
-
84890985901
-
An optimized microRNA backbone for effective single-copy RNAi
-
Fellmann C., Hoffmann T., Sridhar V., Hopfgartner B., Muhar M., Roth M., Lai D.Y., Barbosa I.A., Kwon J.S., Guan Y., et al. An optimized microRNA backbone for effective single-copy RNAi. Cell Rep. 2013, 5:1704-1713.
-
(2013)
Cell Rep.
, vol.5
, pp. 1704-1713
-
-
Fellmann, C.1
Hoffmann, T.2
Sridhar, V.3
Hopfgartner, B.4
Muhar, M.5
Roth, M.6
Lai, D.Y.7
Barbosa, I.A.8
Kwon, J.S.9
Guan, Y.10
-
8
-
-
9144225636
-
The Microprocessor complex mediates the genesis of microRNAs
-
Gregory R.I., Yan K.P., Amuthan G., Chendrimada T., Doratotaj B., Cooch N., Shiekhattar R. The Microprocessor complex mediates the genesis of microRNAs. Nature 2004, 432:235-240.
-
(2004)
Nature
, vol.432
, pp. 235-240
-
-
Gregory, R.I.1
Yan, K.P.2
Amuthan, G.3
Chendrimada, T.4
Doratotaj, B.5
Cooch, N.6
Shiekhattar, R.7
-
9
-
-
34250805982
-
MicroRNA targeting specificity in mammals: determinants beyond seed pairing
-
Grimson A., Farh K.K., Johnston W.K., Garrett-Engele P., Lim L.P., Bartel D.P. MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol. Cell 2007, 27:91-105.
-
(2007)
Mol. Cell
, vol.27
, pp. 91-105
-
-
Grimson, A.1
Farh, K.K.2
Johnston, W.K.3
Garrett-Engele, P.4
Lim, L.P.5
Bartel, D.P.6
-
10
-
-
17844364875
-
Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
-
Grishok A., Pasquinelli A.E., Conte D., Li N., Parrish S., Ha I., Baillie D.L., Fire A., Ruvkun G., Mello C.C. Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 2001, 106:23-34.
-
(2001)
Cell
, vol.106
, pp. 23-34
-
-
Grishok, A.1
Pasquinelli, A.E.2
Conte, D.3
Li, N.4
Parrish, S.5
Ha, I.6
Baillie, D.L.7
Fire, A.8
Ruvkun, G.9
Mello, C.C.10
-
11
-
-
84869037267
-
The loop position of shRNAs and pre-miRNAs is critical for the accuracy of dicer processing in vivo
-
Gu S., Jin L., Zhang Y., Huang Y., Zhang F., Valdmanis P.N., Kay M.A. The loop position of shRNAs and pre-miRNAs is critical for the accuracy of dicer processing in vivo. Cell 2012, 151:900-911.
-
(2012)
Cell
, vol.151
, pp. 900-911
-
-
Gu, S.1
Jin, L.2
Zhang, Y.3
Huang, Y.4
Zhang, F.5
Valdmanis, P.N.6
Kay, M.A.7
-
12
-
-
84904985459
-
Regulation of microRNA biogenesis
-
Ha M., Kim V.N. Regulation of microRNA biogenesis. Nat. Rev. Mol. Cell Biol. 2014, 15:509-524.
-
(2014)
Nat. Rev. Mol. Cell Biol.
, vol.15
, pp. 509-524
-
-
Ha, M.1
Kim, V.N.2
-
13
-
-
10644234841
-
The Drosha-DGCR8 complex in primary microRNA processing
-
Han J., Lee Y., Yeom K.H., Kim Y.K., Jin H., Kim V.N. The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev. 2004, 18:3016-3027.
-
(2004)
Genes Dev.
, vol.18
, pp. 3016-3027
-
-
Han, J.1
Lee, Y.2
Yeom, K.H.3
Kim, Y.K.4
Jin, H.5
Kim, V.N.6
-
14
-
-
33744520104
-
Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex
-
Han J., Lee Y., Yeom K.H., Nam J.W., Heo I., Rhee J.K., Sohn S.Y., Cho Y., Zhang B.T., Kim V.N. Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex. Cell 2006, 125:887-901.
-
(2006)
Cell
, vol.125
, pp. 887-901
-
-
Han, J.1
Lee, Y.2
Yeom, K.H.3
Nam, J.W.4
Heo, I.5
Rhee, J.K.6
Sohn, S.Y.7
Cho, Y.8
Zhang, B.T.9
Kim, V.N.10
-
15
-
-
0037144546
-
A microRNA in a multiple-turnover RNAi enzyme complex
-
Hutvágner G., Zamore P.D. A microRNA in a multiple-turnover RNAi enzyme complex. Science 2002, 297:2056-2060.
-
(2002)
Science
, vol.297
, pp. 2056-2060
-
-
Hutvágner, G.1
Zamore, P.D.2
-
16
-
-
0035800521
-
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
-
Hutvágner G., McLachlan J., Pasquinelli A.E., Bálint E., Tuschl T., Zamore P.D. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 2001, 293:834-838.
-
(2001)
Science
, vol.293
, pp. 834-838
-
-
Hutvágner, G.1
McLachlan, J.2
Pasquinelli, A.E.3
Bálint, E.4
Tuschl, T.5
Zamore, P.D.6
-
17
-
-
84937856311
-
Next-generation libraries for robust RNA interference-based genome-wide screens
-
Kampmann M., Horlbeck M.A., Chen Y., Tsai J.C., Bassik M.C., Gilbert L.A., Villalta J.E., Kwon S.C., Chang H., Kim V.N., Weissman J.S. Next-generation libraries for robust RNA interference-based genome-wide screens. Proc. Natl. Acad. Sci. USA 2015, 112:E3384-E3391.
-
(2015)
Proc. Natl. Acad. Sci. USA
, vol.112
, pp. E3384-E3391
-
-
Kampmann, M.1
Horlbeck, M.A.2
Chen, Y.3
Tsai, J.C.4
Bassik, M.C.5
Gilbert, L.A.6
Villalta, J.E.7
Kwon, S.C.8
Chang, H.9
Kim, V.N.10
Weissman, J.S.11
-
18
-
-
0142165224
-
Functional siRNAs and miRNAs exhibit strand bias
-
Khvorova A., Reynolds A., Jayasena S.D. Functional siRNAs and miRNAs exhibit strand bias. Cell 2003, 115:209-216.
-
(2003)
Cell
, vol.115
, pp. 209-216
-
-
Khvorova, A.1
Reynolds, A.2
Jayasena, S.D.3
-
19
-
-
33846945735
-
Processing of intronic microRNAs
-
Kim Y.K., Kim V.N. Processing of intronic microRNAs. EMBO J. 2007, 26:775-783.
-
(2007)
EMBO J.
, vol.26
, pp. 775-783
-
-
Kim, Y.K.1
Kim, V.N.2
-
20
-
-
84918804365
-
A computational algorithm to predict shRNA potency
-
Knott S.R., Maceli A.R., Erard N., Chang K., Marran K., Zhou X., Gordon A., El Demerdash O., Wagenblast E., Kim S., et al. A computational algorithm to predict shRNA potency. Mol. Cell 2014, 56:796-807.
-
(2014)
Mol. Cell
, vol.56
, pp. 796-807
-
-
Knott, S.R.1
Maceli, A.R.2
Erard, N.3
Chang, K.4
Marran, K.5
Zhou, X.6
Gordon, A.7
El Demerdash, O.8
Wagenblast, E.9
Kim, S.10
-
21
-
-
42949179593
-
In vitro and in vivo assays for the activity of Drosha complex
-
Lee Y., Kim V.N. In vitro and in vivo assays for the activity of Drosha complex. Methods Enzymol. 2007, 427:89-106.
-
(2007)
Methods Enzymol.
, vol.427
, pp. 89-106
-
-
Lee, Y.1
Kim, V.N.2
-
22
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee Y., Ahn C., Han J., Choi H., Kim J., Yim J., Lee J., Provost P., Rådmark O., Kim S., Kim V.N. The nuclear RNase III Drosha initiates microRNA processing. Nature 2003, 425:415-419.
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
Choi, H.4
Kim, J.5
Yim, J.6
Lee, J.7
Provost, P.8
Rådmark, O.9
Kim, S.10
Kim, V.N.11
-
23
-
-
0037423845
-
Vertebrate microRNA genes
-
Lim L.P., Glasner M.E., Yekta S., Burge C.B., Bartel D.P. Vertebrate microRNA genes. Science 2003, 299:1540.
-
(2003)
Science
, vol.299
, pp. 1540
-
-
Lim, L.P.1
Glasner, M.E.2
Yekta, S.3
Burge, C.B.4
Bartel, D.P.5
-
24
-
-
0037447334
-
The microRNAs of Caenorhabditis elegans
-
Lim L.P., Lau N.C., Weinstein E.G., Abdelhakim A., Yekta S., Rhoades M.W., Burge C.B., Bartel D.P. The microRNAs of Caenorhabditis elegans. Genes Dev. 2003, 17:991-1008.
-
(2003)
Genes Dev.
, vol.17
, pp. 991-1008
-
-
Lim, L.P.1
Lau, N.C.2
Weinstein, E.G.3
Abdelhakim, A.4
Yekta, S.5
Rhoades, M.W.6
Burge, C.B.7
Bartel, D.P.8
-
25
-
-
4444368187
-
Argonaute2 is the catalytic engine of mammalian RNAi
-
Liu J., Carmell M.A., Rivas F.V., Marsden C.G., Thomson J.M., Song J.J., Hammond S.M., Joshua-Tor L., Hannon G.J. Argonaute2 is the catalytic engine of mammalian RNAi. Science 2004, 305:1437-1441.
-
(2004)
Science
, vol.305
, pp. 1437-1441
-
-
Liu, J.1
Carmell, M.A.2
Rivas, F.V.3
Marsden, C.G.4
Thomson, J.M.5
Song, J.J.6
Hammond, S.M.7
Joshua-Tor, L.8
Hannon, G.J.9
-
26
-
-
77953642976
-
Titers of lentiviral vectors encoding shRNAs and miRNAs are reduced by different mechanisms that require distinct repair strategies
-
Liu Y.P., Vink M.A., Westerink J.T., Ramirez de Arellano E., Konstantinova P., Ter Brake O., Berkhout B. Titers of lentiviral vectors encoding shRNAs and miRNAs are reduced by different mechanisms that require distinct repair strategies. RNA 2010, 16:1328-1339.
-
(2010)
RNA
, vol.16
, pp. 1328-1339
-
-
Liu, Y.P.1
Vink, M.A.2
Westerink, J.T.3
Ramirez de Arellano, E.4
Konstantinova, P.5
Ter Brake, O.6
Berkhout, B.7
-
27
-
-
84890835664
-
Lower and upper stem-single-stranded RNA junctions together determine the Drosha cleavage site
-
Ma H., Wu Y., Choi J.G., Wu H. Lower and upper stem-single-stranded RNA junctions together determine the Drosha cleavage site. Proc. Natl. Acad. Sci. USA 2013, 110:20687-20692.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 20687-20692
-
-
Ma, H.1
Wu, Y.2
Choi, J.G.3
Wu, H.4
-
28
-
-
30844438338
-
Structural basis for double-stranded RNA processing by Dicer
-
MacRae I.J., Zhou K., Li F., Repic A., Brooks A.N., Cande W.Z., Adams P.D., Doudna J.A. Structural basis for double-stranded RNA processing by Dicer. Science 2006, 311:195-198.
-
(2006)
Science
, vol.311
, pp. 195-198
-
-
MacRae, I.J.1
Zhou, K.2
Li, F.3
Repic, A.4
Brooks, A.N.5
Cande, W.Z.6
Adams, P.D.7
Doudna, J.A.8
-
29
-
-
0037087780
-
MiRNPs: a novel class of ribonucleoproteins containing numerous microRNAs
-
Mourelatos Z., Dostie J., Paushkin S., Sharma A., Charroux B., Abel L., Rappsilber J., Mann M., Dreyfuss G. miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. Genes Dev. 2002, 16:720-728.
-
(2002)
Genes Dev.
, vol.16
, pp. 720-728
-
-
Mourelatos, Z.1
Dostie, J.2
Paushkin, S.3
Sharma, A.4
Charroux, B.5
Abel, L.6
Rappsilber, J.7
Mann, M.8
Dreyfuss, G.9
-
30
-
-
84930478808
-
Functional anatomy of the human Microprocessor
-
Nguyen T.A., Jo M.H., Choi Y.G., Park J., Kwon S.C., Hohng S., Kim V.N., Woo J.S. Functional anatomy of the human Microprocessor. Cell 2015, 161:1374-1387.
-
(2015)
Cell
, vol.161
, pp. 1374-1387
-
-
Nguyen, T.A.1
Jo, M.H.2
Choi, Y.G.3
Park, J.4
Kwon, S.C.5
Hohng, S.6
Kim, V.N.7
Woo, J.S.8
-
31
-
-
84888872901
-
PLogo: a probabilistic approach to visualizing sequence motifs
-
O'Shea J.P., Chou M.F., Quader S.A., Ryan J.K., Church G.M., Schwartz D. pLogo: a probabilistic approach to visualizing sequence motifs. Nat. Methods 2013, 10:1211-1212.
-
(2013)
Nat. Methods
, vol.10
, pp. 1211-1212
-
-
O'Shea, J.P.1
Chou, M.F.2
Quader, S.A.3
Ryan, J.K.4
Church, G.M.5
Schwartz, D.6
-
32
-
-
79960185923
-
Dicer recognizes the 5' end of RNA for efficient and accurate processing
-
Park J.E., Heo I., Tian Y., Simanshu D.K., Chang H., Jee D., Patel D.J., Kim V.N. Dicer recognizes the 5' end of RNA for efficient and accurate processing. Nature 2011, 475:201-205.
-
(2011)
Nature
, vol.475
, pp. 201-205
-
-
Park, J.E.1
Heo, I.2
Tian, Y.3
Simanshu, D.K.4
Chang, H.5
Jee, D.6
Patel, D.J.7
Kim, V.N.8
-
33
-
-
10744225153
-
Asymmetry in the assembly of the RNAi enzyme complex
-
Schwarz D.S., Hutvágner G., Du T., Xu Z., Aronin N., Zamore P.D. Asymmetry in the assembly of the RNAi enzyme complex. Cell 2003, 115:199-208.
-
(2003)
Cell
, vol.115
, pp. 199-208
-
-
Schwarz, D.S.1
Hutvágner, G.2
Du, T.3
Xu, Z.4
Aronin, N.5
Zamore, P.D.6
-
34
-
-
27644436787
-
Second-generation shRNA libraries covering the mouse and human genomes
-
Silva J.M., Li M.Z., Chang K., Ge W., Golding M.C., Rickles R.J., Siolas D., Hu G., Paddison P.J., Schlabach M.R., et al. Second-generation shRNA libraries covering the mouse and human genomes. Nat. Genet. 2005, 37:1281-1288.
-
(2005)
Nat. Genet.
, vol.37
, pp. 1281-1288
-
-
Silva, J.M.1
Li, M.Z.2
Chang, K.3
Ge, W.4
Golding, M.C.5
Rickles, R.J.6
Siolas, D.7
Hu, G.8
Paddison, P.J.9
Schlabach, M.R.10
-
35
-
-
4444302947
-
Crystal structure of Argonaute and its implications for RISC slicer activity
-
Song J.J., Smith S.K., Hannon G.J., Joshua-Tor L. Crystal structure of Argonaute and its implications for RISC slicer activity. Science 2004, 305:1434-1437.
-
(2004)
Science
, vol.305
, pp. 1434-1437
-
-
Song, J.J.1
Smith, S.K.2
Hannon, G.J.3
Joshua-Tor, L.4
-
36
-
-
81255176919
-
Argonaute proteins regulate microRNA stability: increased microRNA abundance by Argonaute proteins is due to microRNA stabilization
-
Winter J., Diederichs S. Argonaute proteins regulate microRNA stability: increased microRNA abundance by Argonaute proteins is due to microRNA stabilization. RNA Biol. 2011, 8:1149-1157.
-
(2011)
RNA Biol.
, vol.8
, pp. 1149-1157
-
-
Winter, J.1
Diederichs, S.2
-
37
-
-
0037273432
-
Sequence requirements for micro RNA processing and function in human cells
-
Zeng Y., Cullen B.R. Sequence requirements for micro RNA processing and function in human cells. RNA 2003, 9:112-123.
-
(2003)
RNA
, vol.9
, pp. 112-123
-
-
Zeng, Y.1
Cullen, B.R.2
-
38
-
-
23044502585
-
Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences
-
Zeng Y., Cullen B.R. Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences. J. Biol. Chem. 2005, 280:27595-27603.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 27595-27603
-
-
Zeng, Y.1
Cullen, B.R.2
-
39
-
-
0036294527
-
Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells
-
Zeng Y., Wagner E.J., Cullen B.R. Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol. Cell 2002, 9:1327-1333.
-
(2002)
Mol. Cell
, vol.9
, pp. 1327-1333
-
-
Zeng, Y.1
Wagner, E.J.2
Cullen, B.R.3
-
40
-
-
12544255565
-
Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha
-
Zeng Y., Yi R., Cullen B.R. Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha. EMBO J. 2005, 24:138-148.
-
(2005)
EMBO J.
, vol.24
, pp. 138-148
-
-
Zeng, Y.1
Yi, R.2
Cullen, B.R.3
-
41
-
-
3142613181
-
Single processing center models for human Dicer and bacterial RNase III
-
Zhang H., Kolb F.A., Jaskiewicz L., Westhof E., Filipowicz W. Single processing center models for human Dicer and bacterial RNase III. Cell 2004, 118:57-68.
-
(2004)
Cell
, vol.118
, pp. 57-68
-
-
Zhang, H.1
Kolb, F.A.2
Jaskiewicz, L.3
Westhof, E.4
Filipowicz, W.5
|