4-hydroxynonenal regulates mitochondrial function in human small airway epithelial cells

Oncotarget

Volumn 6, Issue 39, 2015, Pages 41508-41521

  Galam, Lakshmi ^a   Failla, Athena ^a   Soundararajan, Ramani ^a   Lockey, Richard F ^a   Kolliputi, Narasaiah ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

4 HNE; Acute lung injury; Hyperoxia; Immune response; Immunity; Immunology and Microbiology Section; Mitochondrial dysfunction; ROS

Indexed keywords

4 HYDROXYNONENAL; ADENOSINE TRIPHOSPHATE; CASPASE 3; ROTENONE; THIOREDOXIN; 4-HYDROXY-2-NONENAL; ACONITATE HYDRATASE; ALDEHYDE; CASP3 PROTEIN, HUMAN; OXIDIZING AGENT;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL DAMAGE; CELL FUNCTION; CELL LEVEL; CELL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; ENERGY YIELD; ENZYME ACTIVITY; EPITHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MITOCHONDRIAL RESPIRATION; OXYGEN CONSUMPTION; RESPIRATORY EPITHELIUM; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; ENERGY METABOLISM; FEMALE; HYPEROXIA; LUNG; MALE; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; OXIDATIVE STRESS; PATHOLOGY; TIME FACTOR;

ACONITATE HYDRATASE; ADENOSINE TRIPHOSPHATE; ALDEHYDES; ANIMALS; CASPASE 3; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENERGY METABOLISM; EPITHELIAL CELLS; FEMALE; HUMANS; HYPEROXIA; LUNG; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE, INBRED C57BL; MITOCHONDRIA; OXIDANTS; OXIDATIVE STRESS; OXYGEN CONSUMPTION; THIOREDOXINS; TIME FACTORS;

EID: 84951854894     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.6131     Document Type: Article

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