TYK2 Promoter Variant and Diabetes Mellitus in the Japanese

EBioMedicine

Volumn 2, Issue 7, 2015, Pages 744-749

  Nagafuchi, Seiho ^a,e   Kamada Hibio, Yumi ^a   Hirakawa, Kanako ^a   Tsutsu, Nobutaka ^b   Minami, Masae ^c   Okada, Akira ^d   Kai, Katsuya ^a   Teshima, Miho ^a   Moroishi, Arisa ^a   Murakami, Yoshikazu ^f   Umeno, Yoshikazu ^g   Yokogawa, Yasushi ^h   Kogawa, Kazuhiko ^h   Izumi, Kenichi ⁱ   Anzai, Keizo ⁱ   Iwakiri, Ryuichi ^j   Hamaguchi, Kazuyuki ^k   Sasaki, Nobuhiro ^b   Nohara, Sakae ^b   Yoshida, Eiko ^a   Harada, Mine ^a   Akashi, Koichi ^a   Yanase, Toshihiko ^l,o   Ono, Junko ^l,o   Okeda, Toshimitsu ^l   Fujimoto, Ryoji ^l   Ihara, Kenji ^a   Hara, Toshiro ^a   Kikuchi, Yohei ^a   Iwase, Masanori ^a   Kitazono, Takanari ^a   Kojima, Fumiko ^a   Kono, Suminori ^m   Kurisaki, Hironori ^a   Kondo, Shiori ⁿ   Katsuta, Hitoshi ^a,e   more..

^a KYUSHU UNIVERSITY   (Japan)

^b FUKUOKA RED CROSS HOSPITAL   (Japan)

^c Minami Masae Clinic   (Japan)

^d Okada Clinic   (Japan)

^e Department of Internal Medicine   (Japan)

^f YAMAGUCHI RED CROSS HOSPITAL   (Japan)

^g OITA RED CROSS HOSPITAL   (Japan)

^h HAMANOMACHI HOSPITAL   (Japan)

ⁱ SAGA UNIVERSITY   (Japan)

^j SAGA UNIVERSITY   (Japan)

^k OITA UNIVERSITY   (Japan)

^l FUKUOKA UNIVERSITY   (Japan)

^m Shin Kokura Hospital   (Japan)

ⁿ NATIONAL INSTITUTE OF HEALTH AND NUTRITION   (Japan)

^o MATSUYAMA RED CROSS HOSPITAL   (Japan)

more..

Author keywords

Diabetes mellitus; Polymorphism; Promoter variant; Tyrosine kinase 2 (TYK2); Virus

Indexed keywords

ANTI GLUTAMIC ACID DECARBOXYLASE AUTOANTIBODY; AUTOANTIBODY; HEMOGLOBIN A1C; LUCIFERASE; MEMBRANE PROTEIN; TYROSINE KINASE 2; UNCLASSIFIED DRUG; PROTEIN KINASE TYK2;

ADULT; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; DIABETES MELLITUS; EXON; FEMALE; FLU LIKE SYNDROME; GENE; GENE EXPRESSION; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE SEQUENCE; GENOTYPE; HAPLOTYPE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; JAPANESE (PEOPLE); LUCIFERASE ASSAY; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET BETA CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM; TYROSINE KINASE 2 GENE; ADOLESCENT; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; CASE CONTROL STUDY; CHILD; ENZYMOLOGY; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; ONSET AGE; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGE OF ONSET; AGED; AGED, 80 AND OVER; ASIAN CONTINENTAL ANCESTRY GROUP; BASE SEQUENCE; CASE-CONTROL STUDIES; CHILD; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; TYK2 KINASE; YOUNG ADULT;

EID: 84951573859     PISSN: None     EISSN: 23523964     Source Type: Journal    
DOI: 10.1016/j.ebiom.2015.05.004     Document Type: Article

References (32)

1. Casanova J.L., Holland S.M., Notarangelo L.D. Inborn errors of human JAKs and STATs. Immunity 2012, 36:515-528.
2. Coppieters K.T., Boettler T., von Herrath M. Virus infections in type 1 diabetes. Cold Spring Harb. Perspect. Med. 2012, 2:1-14.
3. Derecka M., Gomicka A., Koralov S.B., et al. Tyk2 and stat3 regulate brown adipose tissue differentiation and obesity. Cell Metab. 2012, 16:814-824.
4. Dwivedi O.P., Tabassum R., Chauhan G., et al. Common variants of FTO are associated with childhood obesity in a cross-sectional study of 3,126 urban Indian children. PLoS One 2012, 7:e47772.
5. Fairweather D., Rose N. Type 1 diabetes: virus infection or autoimmune disease?. Nat. Immunol. 2002, 23:338-340.
6. Firmbach-Kraft I., Byers M., Shows T., Dalla-Favera R., Krolewski J.J. Tyk2, prototype of a novel class of non-receptor tyrosine kinase genes. Oncogene 1990, 5:1329-1336.
7. Haskins K., Cooke A. CD4 T cells and their antigens in the pathogenesis of autoimmune diabetes. Curr. Opin. Immunol. 2011, 23:739-745.
8. Ida-Hosonuma M., Iwasaki T., Yoshikawa T., et al. The alpha/beta interferon response controls tissue tropism and pathogenicity of poliovirus. J. Virol. 2005, 79:4460-4469.
9. Imagawa A., Hanafusa T., Miyagawa J., Matsuzawa Y. A novel subtype of type 1 diabetes mellitus characterized by a rapid onset and an absence of diabetes-related antibodies. N. Engl. J. Med. 2000, 342:301-307.
10. Izumi K., Mine K., Inoue Y., et al. Reduced tyrosine kinase 2 (Tyk2) gene expression in β-cells due to natural mutation determines susceptibility to virus-induced diabetes. Nat. Commun. 2015, 6:e6748.
11. Jenson B.A., Rosenberg H.S., Notkins A.L. Pancreatic islet-cell damage in children with fatal viral infections. Lancet 1980, II:354-358.
12. Jonietz E. Cause and effect. Nature 2012, 485:S10-S11.
13. Kounoue E., Izumi K., Ogawa S., et al. The significance of T cells, B cells, antibodies and macrophages against encephalomyocarditis (EMC)-D virus-induced diabetes in mice. Arch. Virol. 2008, 153:1223-1231.
14. McCarthy M.I. Genomics, type 2 diabetes, and obesity. N. Engl. J. Med. 2010, 363. (2339-2250).
15. Mein C.A., Esposito L., Dunn M.G., et al. A search for type 1 diabetes susceptibility genes in families from the United Kingdom. Nat. Genet. 1998, 19:297-300.
16. Nagafuchi S., Kurisaki H., Katsuta H. Encephalomyocarditis virus. Diabetes and Viruses 2013, 37-48. Springer Science+Business Media, New York. K.W. Taylor, H. Hyöty, A. Toniolo, A. Zuckerman (Eds.).
17. Nejentsev S., Walker N., Riches D., Egholm M., Todd J.A. Rare variants of IFIH1, a gene implicated in antiviral response, protect against type 1 diabetes. Science 2009, 324:387-389.
18. O'Shea J.J., Holland S.M., Staudt L.M. JAKs and STATs in immunity, immunodeficiency, and cancer. N. Engl. J. Med. 2013, 368:161-170.
19. Oikarinen S., Martiskainen M., Tauriainene S., et al. Enterovirus RNA in blood is linked to the development of type 1 diabetes. Diabetes 2011, 60:276-279.
20. Scully T. Diabetes in numbers. Nature 2012, 485:S2-S3.
21. Shimoda K., Kato K., Aoki K., et al. Tyk2 plays a restricted role in IFNα signaling, although it is required for IL-12 mediated T cell function. Immunity 2000, 13:561-571.
22. Smyth D.J., Cooper J.D., Bailey R., et al. A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region. Nat. Genet. 2006, 38:617-619.
23. Stene L.C., Oikarinene S., Hyöty H., et al. Enterovirus infection and progression from islet autoimmunity to type 1 diabetes: the diabetes and autoimmunity study in the young (DAISY). Diabetes 2010, 259:3174-3180.
24. Strobl B., Soiber D., Sexl V., Mueller M. Tyrosine kinase 2 (TYK2) in cytokine signaling and host immunity. Front. Biosci. 2011, 16:3214-3232.
25. Tabrah F.L. Koch's postulates, carnivorous cows, and tuberculosis today. Hawaii Med. J. 2011, 70:144-148.
26. Takeuchi O., Akira S. Innate immunity to virus infection. Immunol. Rev. 2009, 227:75-86.
27. Tanaka S., Nishida Y., Aida K., et al. Enterovirus infection, CXC chemokine ligand 10 (CXCL10), and CXCR3 circuit. Diabetes 2009, 58:2285-2291.
28. Tauriainen S., Oikarinen S., Oikarinen M., Hyöty H. Enteroviruses in the pathogenesis of type 1 diabetes. Semin. Immunopathol. 2011, 33:45-55.
29. Taylor K.W. Historical background: earlier studies on the connection between viruses and diabetes. Diabetes and Viruses 2013, 3-6. Springer Science+Business Media, New York. K.W. Taylor, H. Hyöty, A. Toniolo, A. Zuckerman (Eds.).
30. The 1000 Genomes Project Consortium A map of human genome variation from population-scale sequencing. Nature 2010, 467:1061-1073.
31. The 1000 Genomes Project Consortium An integrated map of genetic variation from 1092 human genomes. Nature 2012, 491:56-65.
32. Toniolo A., Onodera T., Yoon J.W., Notkins A.L. Induction of diabetes by cumulative environmental insults from virus and chemicals. Nature 1980, 288:383-385.