Isolation of potent CGRP neutralizing antibodies using four simple assays

Journal of Biomolecular Screening

Volumn 21, Issue 1, 2016, Pages 24-34

  Neal, Frances ^a   Arnold, Joanne ^a   Rossant, Christine J ^a,b   Podichetty, Sadhana ^a   Lowne, David ^a,c   Dobson, Claire ^a   Wilkinson, Trevor ^a   Colley, Caroline ^a   Howes, Rob ^a   Vaughan, Tristan J ^a  

^a MEDIMMUNE   (United States)

^b CRESCENDO BIOLOGICS LTD   (United Kingdom)

^c Immunocore Limited   (United Kingdom)

Author keywords

antibody; CGRP; screening assays

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; NEUTRALIZING ANTIBODY; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; EPITOPE; MONOCLONAL ANTIBODY;

ANTIBODY LIBRARY; ARTICLE; BINDING ASSAY; CAMP ASSAY; CROSS REACTION; FLUORESCENCE; HOMOGENOUS TIME RESOLVED FLUORESCENCE BINDING ASSAY; HUMAN; INTERFEROMETRY; KINETICS; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; RIBOSOME; BIOASSAY; CELL LINE; IMMUNOLOGY; PROCEDURES;

ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; BIOLOGICAL ASSAY; CALCITONIN GENE-RELATED PEPTIDE; CELL LINE; EPITOPES; FLUORESCENCE; HUMANS;

EID: 84951098481     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057115610070     Document Type: Article

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