Protective effect of thymol on high fat diet induced diabetic nephropathy in C57BL/6J mice

Chemico-Biological Interactions

Volumn 245, Issue , 2016, Pages 1-11

  Saravanan, Settu ^a   Pari, Leelevinothan ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

Diabetic nephropathy; Glomerulosclerosis; High fat diet; Lipids; Thymol

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; CATALASE; CHOLESTEROL; CREATININE; FATTY ACID; GLUCOSE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; INSULIN; LIPID HYDROPEROXIDE; PHOSPHOLIPID; PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THYMOL; TRANSFORMING GROWTH FACTOR BETA1; TRIACYLGLYCEROL; UREA; VASCULOTROPIN; ANTIINFECTIVE AGENT; CREATINE; GLUCOSE BLOOD LEVEL; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; VASCULOTROPIN A;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; CREATININE URINE LEVEL; DIABETIC NEPHROPATHY; DOWN REGULATION; ERYTHROCYTE; GLOMERULOSCLEROSIS; GLUCOSE BLOOD LEVEL; GLUCOSE URINE LEVEL; HISTOPATHOLOGY; INSULIN BLOOD LEVEL; KIDNEY HYPERTROPHY; KIDNEY MASS; KIDNEY PARENCHYMA; LIPID ANALYSIS; LIPID DIET; LIPID STORAGE; MALE; MOUSE; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN URINE LEVEL; RENAL PROTECTION; UREA NITROGEN BLOOD LEVEL; UREA URINE LEVEL; URINE LEVEL; ADVERSE EFFECTS; ANALYSIS; ANIMAL; BLOOD; C57BL MOUSE; DIABETIC NEPHROPATHIES; DRUG EFFECTS; KIDNEY; LIPID PEROXIDATION; METABOLISM; PATHOLOGY;

ANIMALS; ANTI-INFECTIVE AGENTS; BLOOD GLUCOSE; CREATINE; DIABETIC NEPHROPATHIES; DIET, HIGH-FAT; INSULIN; KIDNEY; LIPID PEROXIDATION; MALE; MICE, INBRED C57BL; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; THYMOL; TRANSFORMING GROWTH FACTOR BETA1; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84950990513     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2015.11.033     Document Type: Article

References (59)

1. H.J. Heerspink, and D. de Zeeuw The kidney in type 2 diabetes therapy Rev. Diabet. Stud. 8 2011 392 402
2. Y.S. Kang, J.J. Cha, Y.Y. Hyun, and D.R. Cha Novel C-C chemokine receptor 2 antagonists in metabolic disease: a review of recent developments Expert. Opin. Investig. Drugs 20 2011 745 756
3. G. Reaven, F. Abbasi, and T. McLaughlin Obesity, insulin resistance, and cardiovascular disease Recent. Prog. Horm. Res. 59 2004 207 223
4. S.O. Olusi Obesity is an independent risk factor for plasma lipid peroxidation and depletion of erythrocyte cytoprotecticve enzymes in humans Int. J. Obes. 26 2002 1159 1164
5. M. Mathur, D. Marine, D.A. Lu, R. Swartz-Basile, N.J. Saxena, and H.A. Zyromski Pitt, Nonalcoholic fatty pancreas disease HPB Oxf. 9 2007 312 318
6. H. Wickman Kramer, Obesity and kidney disease: potential mechanisms Semin. Nephrol. 33 2013 14 22
7. H. Abuissa, and J. O'Keefe Jr. T he role of renin-angiotensin-aldosterone system-based therapy in diabetes prevention and cardiovascular and renal protection Diabetes Obes. Metab. 10 2008 1157 1166
8. N. Tanji, G.S. Markowitz, C. Fu, T. Kislinger, A. Taguchi, M. Pischetsrieder, D. Stern, A.M. Schmidt, and V.D. D'Agati Expression of advanced glycation end products and their cellular receptor RAGE in diabetic nephropathy and nondiabetic renal disease J. Am. Soc. Nephrol. 11 2000 1656 1666
9. Q. Liang, E.C. Carlson, R.V. Donthi, P.M. Kralik, X. Shen, and P.N. Epstein Overexpression of metallothionein reduces diabetic cardiomyopathy Diabetes 51 2002 174 181
10. K. Susztak, E. Bottinger, A. Novetsky, D. Liang, Y. Zhu, E. Ciccone, D. Wu, S. Dunn, P. McCue, and K. Sharma Molecular profiling of diabetic mouse kidney reveals novel genes linked to glomerular disease Diabetes 53 2004 784 794
11. R.S. Surwit, M.N. Feinglos, and J. Rodin Differential effects of fat and sucrose on the development of obesity and diabetes in C57BL/6J and A/J mice Metabolism 44 1995 645 651
12. G. Proctor, T. Jiang, M. Iwahashi, and et al. Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in Akita and OVE26 mice with type 1 diabetes Diabetes 55 2006 2502 2509
13. S.E. Inzucchi Oral antihyperglycemic therapy for type 2 diabetes: scientific review J. Am. Med. Assoc. 287 2002 360 372
14. Wattanasatchaa, S. Rengpipat, and S. Wanichwecharungruang Thymol nanospheres as an effective anti-bacterial agent Int. J. Pharma 434 2012 360 365
15. M.I. Segvić Klarić, I. Kosalec, J. Mastelić, E. Piecková, and S. Pepeljnak Antifungal activity of thyme (Thymus vulgaris L.) essential oil and thymol against moulds from damp dwellings Lett. Appl. Microbiol. 44 2007 36 42
16. P.C. Braga, M. Dal Sasso, M. Culici, T. Bianchi, L. Bordoni, and L. Marabini Antiinflammatory activity of thymol: inhibitory effect on the release of human neutrophil elastase Pharmacology 77 2006 130 136
17. P.R.A.B. Nageshwar Rao, and B.S. Satish Rao In vivo radioprotective potential of thymol, a monoterpene phenol derivative of cymene Mutat. Res. 726 2011 136 145
18. M.F. Nagoor Meeran, and P.S. Prince Protective effects of thymol on altered plasma lipid peroxidation and nonenzymic antioxidants in isoproterenol-induced myocardial infarcted rats J. Biochem. Mol. Toxicol. 26 2012 368 373
19. S. Dhaneshwar, V. Patel, D. Patil, and G. Meena Studies on synthesis, stability, release and pharmacodynamic profile of a novel diacerein-thymol prodrug Bioorg. Med. Chem. Lett. 23 2009 55 61
20. S. Muthulakshmi, and R. Saravanan Efficacy of azelaic acid on hepatic key enzymes of carbohydrate metabolism in high fat diet induced type 2 diabetic mice Biochimie 95 2013 1239 1244
21. P. Trinder Determination of blood glucose using an oxidase peroxidase system with a non carcinogenic chromogen J. Clin. Pathol. 22 1969 158 161
22. W. Burgi, M. Briner, N. Franken, and A.C. Kessler One-step sandwich enzyme immunoassay for insulin using monoclonal antibodies Clin. Biochem. 21 1998 311 314
23. D.W. Cockcroft, and M.H. Gault Prediction of creatinine from serum creatinine Nephron 16 1976 31 41
24. S. Netlson, M.L. Scott, and C. Beffa A rapid method for the estimation of urea in biologic fluids Am. J. Pathol. 21 1951 275 281
25. M. Jaffe Concerning the precipitate produced in normal urine by picric acid and a new reaction of creatinine Physio. Chem. 10 1886 91 400
26. O.H. Lowry, N.J. Rosebrough, A.L. Farr, and R.J. Randall Protein measurement with the Folin phenol reagent J. Biol. Chem. 193 1951 265 275
27. W.G. Niehaus, and B. Samuelsson Formation of malondialdehyde from phospholipid arachidonate during microsomal lipid peroxidation Eur. J. Biochem. 6 1968 126 130
28. Z.Y. Jiang, J.V. Hunt, and S.P. Wolff Ferrous ion oxidation in the presence of xylenol orange for detection of lipid hydroperoxides in low density lipoprotein Anal. Biochem. 202 1992 384 389
29. H.P. Misra, and I. Fridovich The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase J. Biol. Chem. 247 1972 70 75
30. H. Aebi Catalase in Vitro third ed. Methods in Enzymology vol. 105 1984 Lippincott-Raven Publishers Philadelphia 121 126
31. G.L. Ellman Tissue sulfhydryl groups Arch. Biochem. Biophys. 82 1959 70 77
32. W.H. Habig, M.J. Pabst, and W.B. Jakoby Glutathione S-transferases. The first enzymatic step in mercapturic acid formation J. Biol. Chem. 249 1974 7130 7139
33. J.T. Rotruck, A.L. Pope, H.E. Ganther, A.B. Swanson, D.G. Hafeman, and W.G. Hoekstra Selenium: biochemical role as a component of glutathione peroxidise Science 179 1973 588 590
34. R.E. Pinto, and W. Bartley The effect of age and sex on glutathione reductase and glutathione peroxidase activities on aerobic glutathione oxidation in rat liver homogenate Biochem. J. 12 1969 109 115
35. J.H. Roe, and C.A. Kuether The determination of ascorbic acid in whole blood and urine through the 2, 4-dinitrophenylhydrazine derivative of dehydroascorbic acid J. Biol. Chem. 11 1943 145 164
36. H. Baker, O. Frank, B. DeAngelis, and S. Feingold Plasma tocopherol in man at various times after ingesting free or acetylated tocopherol Nutr. Res. 21 1980 531 536
37. J. Folch, M. Lees, and S.G.H. Solane A simple method for isolation and purification of total lipids from animal tissues J. Biol. Chem. 226 1957 497 509
38. U.K. Laemmli Cleavge of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 685
39. Y.S. Kang, J.J. Cha, Y.Y. Hyun, and D.R. Cha Novel C-C: chemokine receptor 2 antagonists in metabolic disease: a review of recent developments Expert Opin. Investig. Drugs 20 2011 745 756
40. J.A. Jefferson, S.J. Shankland, and R.H. Pichler Proteinuria in diabetic kidney disease: a mechanistic viewpoint Kidney Int. 74 2008 22 36
41. M.J. Soler, M. Riera, and D. Batlle New experimental models of diabetic nephropathy in mice models of type 2 diabetes: efforts to replicate human nephropathy Exp. Diabetes Res. 2012 2012 616313
42. S. Saravanan, and L. Pari Role of thymol on hyperglycaemia and hyperlipidemia in High fat diet-induced type 2 diabetic C57BL/6J mice Eur. J. Pharmacol. 761 2015 279 287
43. P. Pasupathi, V. Chandrasekar, and U. Senthil Kumar Evaluation of oxidative stress, enzymatic and non-enzymatic antioxidants and metabolic thyroid hormone status in patients with diabetes mellitus Diabetes Metabol. Syn. Clin. Res. Rev. 3 2009 160 165
44. W. Xue, J. Lei, X. Li, and R. Zhang Trigonella foenum graecum seed extract protects kidney function and morphology in diabetic rats viaits antioxidant activity Nutr. Res. 31 2011 555 562
45. H. Birn, and E.I. Christensen Renal albumin absorption in physiology and pathology Kidney Int. 69 2006 440 449
46. D.I. Feig, M. Mazzali, D.H. Kang, T. Nakagawa, K. Price, J. Kannelis, and et al. Serum uric acid: a risk factor and a target for treatment? J. Amer. Soc. Nephrol. 17 2006 69 73
47. K. Jandeleit-Dahm, Z. Cao, A.J. Cox, D.J. Kelly, R.E. Gilbert, and M.E. Cooper Role of hyperlipidemia in progressive renal disease: focus on diabetic nephropathy Kidney Int. Suppl. 71 1999 31 36
48. X. Ruan, F. Zheng, and Y. Guan PPARs and the kidney in metabolic syndrome Am. J. Physiol. Ren. Physiol. 294 2008 1032 1047
49. H. Ha, and K.H. Kim Pathogenesis of diabetic nephropathy: The role of oxidative stress and protein kinase C Diabetes Res. Clin. Pract. 45 1999 147 151
50. R.L. Auten, and J.M. Davis Oxygen toxicity and reactive oxygen species: the devil is in the details Pediatr. Res. 66 2009 121 127
51. P. Gangadhara, V. Achari, and V. Elangovan Beneficial effects of aminoguanidine against streptozotocin-induced pathological changes in diabetic mice kidney Biomed. Pre. Nutr. 3 2013 221 226
52. H. Ha, and H.B. Lee Oxidative stress in diabetic nephropathy: basic and clinical information Curr. Diab. Rep. 1 2001 282 287
53. S.I. Rizvi, and P.K. Maurya Markers of oxidative stress in erythrocytes during aging in humans Ann. N. Y. Acad. Sci. 1100 2007 373 382
54. J. Prakash Dyslipidemia in diabetic kidney disease Clin. Queries Nephrol. 0102 2012 115 118
55. T. Jiang, Z. Wang, G. Proctor, S. Moskowitz, S.E. Liebman, T. Rogers, M.S. Lucia, and J.M. Levi Diet-induced obesity in C57BL/6J mice causes increased renal lipid accumulation and glomerulosclerosis via a sterol regulatory element-binding protein-1cdependent pathway J. Biol. Chem. 280 2005 32317 32325
56. M.S. Brown, and J.L. Goldstein The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor Cell 89 1997 331 340
57. N. Deji, S. Araki, M. Soumura, T. Sugimoto, K. Isshiki, M. Chin-Kanasaki, M. Sakaguchi, D. Koya, M. Haneda, A. Kashiwagi, and T. Uzu Structural and functional changes in the kidneys of high-fat diet-induced obese mice Am. J. Physiol. Ren. Physiol. 296 2009 118 126
58. S. Kume, T. Uzu, S. Araki, T. Sugimoto, K. Isshiki, M. Chin-Kanasaki, M. Sakaguchi, N. Kubota, Y. Terauchi, T. Kadowaki, M. Haneda, A. Kashiwagi, and D. Koya Role of altered renal lipid metabolism in the development of renal injury induced by a high-fat diet J. Am. Soc. Nephrol. 18 2007 2715 2723
59. N. Kandasamy, and N. Ashokkumar Renoprotective effect of myricetin restrains dyslipidemia and renal mesangial cell proliferation by the suppression of sterol regulatory element binding proteins in an experimental model of diabetic nephropathy Eur. J. Pharmacol. 743 2014 53 62