Protective effects of thymol on altered plasma lipid peroxidation and nonenzymic antioxidants in isoproterenol-induced myocardial infarcted rats

Journal of Biochemical and Molecular Toxicology

Volumn 26, Issue 9, 2012, Pages 368-373

  Nagoor Meeran, Mohamed Fizur ^a   Stanely Mainzen Prince, Ponnian ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

Antioxidants; Cardiac Marker Enzyme; Isoproterenol; Lipid Peroxidation; Myocardial Infarction; Thymol

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; CREATINE KINASE MB; GLUTATHIONE; ISOPRENALINE; LIPID HYDROPEROXIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THYMOL;

ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; HEART INFARCTION; HEART PROTECTION; LIPID PEROXIDATION; MALE; NONHUMAN; PROTEIN BLOOD LEVEL; RAT;

ANIMALS; ANTIOXIDANTS; CARDIOTONIC AGENTS; CREATINE KINASE, MB FORM; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE; ISOPROTERENOL; LIPID PEROXIDATION; MALE; MYOCARDIAL INFARCTION; RATS; RATS, WISTAR; REDUCING AGENTS; THIOBARBITURIC ACID REACTIVE SUBSTANCES; THYMOL;

RATTUS; RATTUS NORVEGICUS;

EID: 84866454503     PISSN: 10956670     EISSN: 10990461     Source Type: Journal    
DOI: 10.1002/jbt.21431     Document Type: Article

References (22)

1. Patel V, Upaganlawar A, Zalawadia R, Balaraman R. Cardioprotective effect of melatonin against isoproterenol induced myocardial infarction in rats: a biochemical, electrocardiographic and histoarchitectural evaluation. Eur J Pharmacol 2010;644:160-168.
2. Rajadurai M, Stanely Mainzen Prince P. Preventive effect of naringin on lipid peroxides and antioxidants in isoproterenol-induced cardiotoxicity in Wistar rats: biochemical and histopathological evidences. Toxicology 2006;228:259-268.
3. Mari Kannan M, Darlin Quine S. Ellagic acid ameliorates isoproterenol induced oxidative stress: Evidence from electrocardiological, biochemical and histological study. Eur J Pharmacol 2011;659:45-52.
4. Zhou R, Xu Q, Zheng P, Yan L, Zheng J, Dai G. Cardioprotective effect of fluvastatin on isoproterenol-induced myocardial infarction in rat. Eur J Pharmacol 2008;586:244-250.
5. Ulrich-Merzenich G, ZeitlerH, VetterH, Kraft K. Synergy research: vitamins and secondary plant components in the maintenance of the redox homeostasis and in cell signaling. Phytomedicine 2009;16:2-16.
6. Archana PR, Nageshwar Rao B, Satish Rao BS. In vivo radioprotective potential of thymol, a monoterpene phenol derivative of cymene. Mutat Res 2011;726:136-145.
7. Buyukleyla M, Rencuzogullari E. The effects of thymol on sister chromatid exchange, chromosome aberration and micronucleus inhumanlymphocytes. Ecotoxicol Environ Saf 2009;72:943-947.
8. Hsu SS, Lin KL, Chou CT, Chiang AJ, Liang WZ, Chang HT, Tsai JY, Liao WC, Huang FD, Huang JK, Chen IS, Liu SI, Kuo CC, Jan CR. Effect of thymol on Ca2+ homeostasis and viability in human glioblastoma cells. Eur J Pharmacol 2011;670:85-91.
9. Gujar JG, Wagh SJ, Gaikar VG. Experimental and modeling studies on microwave-assisted extraction of thymol from seeds of Trachyspermum ammi (TA). Sep Purif Technol 2010;70:257-264.
10. Zamureenko VA, Klyuev NA, Bocharov BV, Kabanov VS, Zakharov AM. An investigation of the component composition of the essential oil of Monarda fistulosa. Chem Nat Compd 1989;25:549-551.
11. Ghosheh OA, Houdi AA, Crooks PA. High performance liquid chromatographic analysis of the pharmacologically active quinones and related compounds in the oil of the black seed (Nigella sativa L). J Pharm Biomed Anal 1999;19:757-762.
12. Stanely Mainzen Prince P. (2011). A biochemical, electrocardiographic, electrophoretic, histopathological and in vitro study on the protective effects of (-) epicatechin in isoproterenol-induced myocardial infarcted rats. Eur J Pharmacol 2011;671:95-101.
13. Yagi K. Lipid peroxides and human disease. Chem Phys Lipids 1987;45:337-351.
14. Jiang ZY, Hunt JV, Wolff SP. Ferrous ion oxidation in the presence of xylenol orange for detection of lipid hydroperoxides in low-density lipoprotein. Anal Biochem 1992;202:384-389.
15. Rao KS, Recknagel RO. Early onset of lipid peroxidation in rat liver after carbon tetrachloride administration. Exp Mol Pathol 1968;9:271-278.
16. Ellman GC. Tissue sulfhydryl groups. Arch Biochem Biophys 1959;82:70-77.
17. Omaye ST, Turnbull TD, Sauberlich HE. Selected method for the determination of ascorbic acid in animal cells, tissues and fluids. Methods Enzymol 1979;62:3-11.
18. Baker H, Frank O, Angelis B, Feingold S. Plasma tocopherol in man at various times after ingesting free or acetylated tocopherol. Nutr Rep Int 1980;21:531-536.
19. Oyaizu M. Studies on product of browning reaction prepared from glucose amine. Jpn J Nutr 1986;44:307-315.
20. Padmanabhan M, Stanely Mainzen Prince P. Preventive effect of S-allylcysteine on lipid peroxides and antioxidants in normal and isoproterenol induced cardiotoxicity in rats: a histopathological study. Toxicology 2006;224:128-137.
21. Hsu B, Coupar IM, Ng K. Antioxidant activity of hot water extract from the fruit of the Doum palm, Hyphaene thebaica. Food Chem 2006;98:317-328.
22. Siddhuraju P, Becker K. The antioxidant and free radical scavenging activities of processed cowpea (Vigna unguiculata (L.) Walp.) seed extracts. Food Chem 2007;101:10-19.