Antifungal activity of thyme (Thymus vulgaris L.) essential oil and thymol against moulds from damp dwellings

Letters in Applied Microbiology

Volumn 44, Issue 1, 2007, Pages 36-42

  Segvic Klaric M ^a   Kosalec, I ^a   Mastelic J ^b   Pieckova E ^c   Pepeljnak, S ^a  

^a UNIVERSITY OF ZAGREB   (Croatia)

^b UNIVERSITY OF SPLIT   (Croatia)

^c SLOVAK MEDICAL UNIVERSITY   (Slovakia)

Author keywords

Antifungal activity; Damp walls; Moulds; Thyme essential oil; Thymol

Indexed keywords

FUNGI; HOUSING; MOLDS; PHENOLS; THYMUS;

ALTERNARIA; ANTIFUNGAL ACTIVITIES; CLADOSPORIUM; CROATIA; DAMP DWELLINGS; DAMP WALL; MOLD; THYME ESSENTIAL OIL; THYMOL; THYMUS VULGARIS L;

ESSENTIAL OILS;

CINEOLE; ESSENTIAL OIL; PARA CYMENE; THYME OIL; THYMOL;

APPROXIMATION THEORY; BACTERIA; CONCENTRATION (PROCESS); DISINFECTION; ESSENTIAL OILS; FUNGI;

ANTIMICROBIAL ACTIVITY; ESSENTIAL OIL; FUNGUS; HERB; HUMID ENVIRONMENT; INHIBITION; PERENNIAL PLANT; WALL;

ABSIDIA; ALTERNARIA; ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS; CHAETOMIUM; CLADOSPORIUM; COMPARATIVE STUDY; CONTROLLED STUDY; CROATIA; DILUTION; DRUG EXPOSURE; FUNGAL STRAIN; FUNGICIDAL ACTIVITY; FUNGUS; IN VITRO STUDY; INHIBITION KINETICS; ISOLATION PROCEDURE; MINIMUM INHIBITORY CONCENTRATION; MOULD; MUCOR; NONHUMAN; PENICILLIUM; RHIZOPUS; SAMPLE; SLOVAKIA; SPECIES; SPOROGENESIS; STACHYBOTRYS CHARTARUM; THYME; TRICHODERMA; ULOCLADIUM; VAPOR;

CENTRAL EUROPE; CROATIA; EURASIA; EUROPE; SLOVAKIA; SOUTHERN EUROPE; ZAGREB;

ABSIDIA; ALTERNARIA; ASPERGILLUS; CHAETOMIUM; CLADOSPORIUM; MUCOR; PENICILLIUM; RHIZOPUS; STACHYBOTRYS CHARTARUM; THYMUS VULGARIS; TRICHODERMA; ULOCLADIUM;

EID: 33845757537     PISSN: 02668254     EISSN: 1472765X     Source Type: Journal    
DOI: 10.1111/j.1472-765X.2006.02032.x     Document Type: Article

References (27)

1. Adams, R.P. (1995) Identification of Essential Oil Components by Gas Chromatography/Mass Spectrometry. Illinois: Allured Publishing Coorporation.
2. Bünger, J., Westphal, G., Mönnich, A., Hinnendahl, B., Hallier, E. and Müller, M. (2004) Cytotoxicity of occupationally and environmentally relevant mycotoxins. Toxicology 202, 199-211.
3. Burt, S. (2004) Essential oils: their antibacterial properties and potential applications in foods - a review. Int J Food Microbiol 94, 223-253.
4. Flappan, S.M., Portnoy, J., Jones, P. and Barnes, C. (1999) Infant pulmonaryhemorrhage in a suburban home with water damage and mold (Stachybotrys atra). Environ Health Perspect 107, 927-930.
5. Grant, C., Hunter, C.A., Flannigan, B. and Bravery, A.F. (1989) The moisture requirements of moulds isolated from domestic dwelling. Int Biodeterior 25, 259-284.
6. Gravesen, S., Nielson, P.A., Iversen, R. and Nielsen, K.F. (1999) Microfungal contamination of damp buildings-examples of risk constructions and risk materials. Environ Health Perspect 107(Suppl. 3), 505-508.
7. Hammer, K.A., Carson, C.F. and Riley, T.V. (2003) Antifungal activity of the components of Melaleuca alternifolia (tea tree) oil. J Appl Microbiol 95, 853-860.
8. de Hoog, G.S., Guarro, J., Gene, J. and Figueras, M.J. (2000) Atlas of Clinical Fungi, 2nd edn. Baard-Delft: Centraalbureau voor Schimmelcultures/ Universitat Rovira i Virgili.
9. Hossain, M.A., Ahmed, M.S. and Ghannoum, M.A. (2004) Attributes of Stachybotrys charatrum and its association with human disease. J Allergy Clin Immunol 113, 200-208.
10. Inouye, S., Watanabe, M., Nishiyama, Y., Takeo, K., Akao, M. and Yamaguchi, H. (1998) Antisporulating and respiration-inhibitory effects of essential oils on filamentous fungi. Mycoses 41, 403-440.
11. López-Malo, A., Alzamora, S.M. and Palou, E. (2005) Aspergillus flavus growth in the presence of chemical preservatives and naturally occurring antimicrobial compounds. Int J Food Microbiol 99, 119-128.
12. Nielsen, K.F. (2003) Mycotoxin production by indoor molds. Fungal Genet Biol 39, 103-117.
13. Pasanen, A.-L., Korpi, A., Kasanen, J.P. and Pasanen, P. (1998) Critical aspects on the significance of microbial volatile metabolites as indoor pollutants. Environ Int 24, 703-712.
14. Pauli, A. (2001) Antimicrobial properties of essential oil constituents. Int J Aromatherapy 11, 126-133.
15. Pepeljnjak, S., Kosalec, I., Kalodera, Z. and Kuštrak, D. (2003) Natural antimycotics from Croatian plants. In Plant-Derived Antimycotics ed. Rai, M. and Mares, D. pp. 49-81. Binghampton: The Haworth Press.
16. Piecková, E. and Jesenská, Z. (1999) Microscopic fungi in dwellings and their health implications in humans. Ann Agric Environ Med 6, 1-11.
17. Piecková, E. and Kunová, Z. (2002) Indoor fungi and their ciliostatic metabolites. Ann Agric Environ Med 9, 59-63.
18. Piecková, E., Hurbánková, M., Pivovarová, Z., Černá, S., Kováčiková, Z., Lišková, A., Tatrai, E. and Šegvić, M. (2004) Toxicity of indoor Stachybotrys chartarum. Toxicol Appl Pharmacol 197, 443.
19. Pina-Vaz, C., Rodrigues, A.G., Pinto, E., Costa-de-Olivera, S., Tavares, C., Salgueiro, L., Cavaleiro, C., Goncalves, M.J. et al. (2004) Antifungal activity of Thymus oils and other major compounds. JEADV 18, 73-78.
20. Rakotonirainy, M.S. and Lavédrine, B. (2005) Screening for antifungal activity of essential oils and related compounds to control the biocontamination in libraries and archives storage areas. Int Biodeterior Biodegrad 55, 141-147.
21. Raper, K.B. and Thom, C. (1949) A Manual of the Penicillia. Baltimore: The Williams and Wilkins Company.
22. Rasooli, I. and Owlia, P. (2005) Chemoprevention by thyme oils of Aspergillus parasiticus growth and aflatoxin production. Phytochemistry 66, 2851-2856.
23. Rylander, R. (1997) Airborne (1 → 3)-beta-d-glucan and airway disease in a day-care center before and after renovation. Arch Environ Health 52, 281-285.
24. Samson, R.A., Hoekstra, E.S. and van Oorschot, C.A.N. (1981) Introduction to Food-Borne Fungi. Utrecht: Institute of the Royal Netherlands Academy of Art and Sciences.
25. Schulz, T., Senkpiel, K. and Ohgke, H. (2004) Comparison of the toxicity of reference mycotoxins and spore extracts of common indoor moulds. Int J Hyg Environ Health 207, 267-277.
26. Sokeman, A., Gulluce, M., Akpulat, H.A., Daferera, D., Tepe, B., Polissiou, M., Sokmen, M. and Sahin, F. (2004) The in vitro antimicrobial and antioxidant activities of the essential oils and methanol extracts of endemic Thymus spathulifolius. Food Control 15, 627-634.
27. Viollon, C. and Chaumont, J.-P. (1994) Antifungal properties of essential oils and their main components upon Cryptococcus neoformans. Mycopathologia 128, 151-153.