Antibody against Small Aggregated Peptide Specifically Recognizes Toxic Aβ-42 Oligomers in Alzheimer's Disease

ACS Chemical Neuroscience

Volumn 6, Issue 12, 2015, Pages 1981-1989

  Bodani, Riddhi U ^a   Sengupta, Urmi ^a   Castillo Carranza, Diana L ^a   Guerrero Muñoz, Marcos J ^a   Gerson, Julia E ^a   Rudra, Jai ^b   Kayed, Rakez ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b Departments of Neurology and Neuroscience and Cell Biology ^*  (United States)

Author keywords

Amyloid oligomers; repeated sequence; small peptide

Indexed keywords

ALANINE; ALANINE DERIVATIVE; AMINO ACID; AMYLOID; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; ANTIBODY; EPITOPE; ISOLEUCINE; MONOCLONAL ANTIBODY; OLIGOMER; PROTEIN AGGREGATE; UNCLASSIFIED DRUG; VALINE; VALYLISOLEUCYLALANYL ANTIBODY; AMYLOID PRECURSOR PROTEIN; PRESENILIN 1; PROTEIN BINDING;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID PLAQUE; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; BRAIN; CONTROLLED STUDY; DEGENERATIVE DISEASE; EX VIVO STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOGENICITY; IMMUNOREACTIVITY; IMMUNOTHERAPY; IN VITRO STUDY; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; AGE; ANIMAL; CHEMISTRY; DRUG EFFECTS; GENETICS; IMMUNOLOGY; METABOLISM; NEUROBLASTOMA; NEUROIMAGING; PATHOLOGY; TRANSGENIC MOUSE;

AGE FACTORS; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANTIBODIES; BRAIN; HUMANS; MICE; MICE, TRANSGENIC; NEUROBLASTOMA; NEUROIMAGING; PRESENILIN-1; PROTEIN BINDING;

EID: 84950288771     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/acschemneuro.5b00231     Document Type: Article

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