메뉴 건너뛰기




Volumn 469, Issue 1, 2016, Pages 49-54

Anti-adipogenic effects of sesamol on human mesenchymal stem cells

Author keywords

Adipogenesis; Human mesenchymal stem cells; Osteogenesis; Sesamol

Indexed keywords

ADIPONECTIN; AGENTS AFFECTING LIPID METABOLISM; GLYCEROL; HERMES ANTIGEN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHENOL DERIVATIVE; SESAME SEED OIL; SESAMOL; THY 1 ANTIGEN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; 1,3 BENZODIOXOLE DERIVATIVE; ANTIOXIDANT;

EID: 84950262496     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.11.070     Document Type: Article
Times cited : (16)

References (41)
  • 1
    • 84859499772 scopus 로고    scopus 로고
    • Noggin is novel inducer of mesenchymal stem cell adipogenesis: Implications for bone health and obesity
    • A. Sawant, D. Chanda, T. Isayeva, G. Tsuladze, W.T. Garvey, and S. Ponnazhagan Noggin is novel inducer of mesenchymal stem cell adipogenesis: implications for bone health and obesity J. Biol. Chem. 287 2012 12241 12249
    • (2012) J. Biol. Chem. , vol.287 , pp. 12241-12249
    • Sawant, A.1    Chanda, D.2    Isayeva, T.3    Tsuladze, G.4    Garvey, W.T.5    Ponnazhagan, S.6
  • 3
    • 34547201694 scopus 로고    scopus 로고
    • Mesenchymal progenitors able to differentiate into osteogenic, chondrogenic, and/or adipogenic cells in vitro are present in most primary fibroblast-like cell populations
    • K. Sudo, M. Kanno, K. Miharada, S. Ogawa, T. Hiroyama, K. Saijo, and Y. Nakamura Mesenchymal progenitors able to differentiate into osteogenic, chondrogenic, and/or adipogenic cells in vitro are present in most primary fibroblast-like cell populations Stem Cells 25 2007 1610 1617
    • (2007) Stem Cells , vol.25 , pp. 1610-1617
    • Sudo, K.1    Kanno, M.2    Miharada, K.3    Ogawa, S.4    Hiroyama, T.5    Saijo, K.6    Nakamura, Y.7
  • 5
    • 65949113378 scopus 로고    scopus 로고
    • Marrow fat and the bone microenvironment: Developmental, functional, and pathological implications
    • C.J. Rosen, C. Ackert-Bicknell, J.P. Rodriguez, and A.M. Pino Marrow fat and the bone microenvironment: developmental, functional, and pathological implications Crit. Rev. Eukaryot. Gene Expr. 19 2009 109 124
    • (2009) Crit. Rev. Eukaryot. Gene Expr. , vol.19 , pp. 109-124
    • Rosen, C.J.1    Ackert-Bicknell, C.2    Rodriguez, J.P.3    Pino, A.M.4
  • 6
    • 0029961204 scopus 로고    scopus 로고
    • The function of adipocytes in the bone marrow stroma: An update
    • J.M. Gimble, C.E. Robinson, X. Wu, and K.A. Kelly The function of adipocytes in the bone marrow stroma: an update Bone 19 1996 421 428
    • (1996) Bone , vol.19 , pp. 421-428
    • Gimble, J.M.1    Robinson, C.E.2    Wu, X.3    Kelly, K.A.4
  • 7
    • 2342613539 scopus 로고    scopus 로고
    • Controlling the balance between osteoblastogenesis and adipogenesis and the consequent therapeutic implications
    • M.E. Nuttall, and J.M. Gimble Controlling the balance between osteoblastogenesis and adipogenesis and the consequent therapeutic implications Curr. Opin. Pharmacol. 4 2004 290 294
    • (2004) Curr. Opin. Pharmacol. , vol.4 , pp. 290-294
    • Nuttall, M.E.1    Gimble, J.M.2
  • 10
    • 13844257282 scopus 로고    scopus 로고
    • Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma/stem cells: The role of PPAR-gamma2 transcription factor and TGF-beta/BMP signaling pathways
    • E.J. Moerman, K. Teng, D.A. Lipschitz, and B. Lecka-Czernik Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma/stem cells: the role of PPAR-gamma2 transcription factor and TGF-beta/BMP signaling pathways Aging Cell 3 2004 379 389
    • (2004) Aging Cell , vol.3 , pp. 379-389
    • Moerman, E.J.1    Teng, K.2    Lipschitz, D.A.3    Lecka-Czernik, B.4
  • 11
    • 0033849777 scopus 로고    scopus 로고
    • Obesity and insulin resistance
    • B.B. Kahn, and J.S. Flier Obesity and insulin resistance J. Clin. Investig. 106 2000 473 481
    • (2000) J. Clin. Investig. , vol.106 , pp. 473-481
    • Kahn, B.B.1    Flier, J.S.2
  • 12
    • 0034842784 scopus 로고    scopus 로고
    • Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis
    • J. Justesen, K. Stenderup, E.N. Ebbesen, L. Mosekilde, T. Steiniche, and M. Kassem Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis Biogerontology 2 2001 165 171
    • (2001) Biogerontology , vol.2 , pp. 165-171
    • Justesen, J.1    Stenderup, K.2    Ebbesen, E.N.3    Mosekilde, L.4    Steiniche, T.5    Kassem, M.6
  • 13
    • 0023276009 scopus 로고
    • Changes in trabecular bone, hematopoiesis and bone marrow vessels in aplastic anemia, primary osteoporosis, and old age: A comparative histomorphometric study
    • R. Burkhardt, G. Kettner, W. Bohm, M. Schmidmeier, R. Schlag, B. Frisch, B. Mallmann, W. Eisenmenger, and T. Gilg Changes in trabecular bone, hematopoiesis and bone marrow vessels in aplastic anemia, primary osteoporosis, and old age: a comparative histomorphometric study Bone 8 1987 157 164
    • (1987) Bone , vol.8 , pp. 157-164
    • Burkhardt, R.1    Kettner, G.2    Bohm, W.3    Schmidmeier, M.4    Schlag, R.5    Frisch, B.6    Mallmann, B.7    Eisenmenger, W.8    Gilg, T.9
  • 14
    • 67650504733 scopus 로고    scopus 로고
    • Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment
    • O. Naveiras, V. Nardi, P.L. Wenzel, P.V. Hauschka, F. Fahey, and G.Q. Daley Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment Nature 460 2009 259 263
    • (2009) Nature , vol.460 , pp. 259-263
    • Naveiras, O.1    Nardi, V.2    Wenzel, P.L.3    Hauschka, P.V.4    Fahey, F.5    Daley, G.Q.6
  • 15
    • 0015137446 scopus 로고
    • Osteoporosis and the replacement of cell populations of the marrow by adipose tissue. A quantitative study of 84 iliac bone biopsies
    • P. Meunier, J. Aaron, C. Edouard, and G. Vignon Osteoporosis and the replacement of cell populations of the marrow by adipose tissue. A quantitative study of 84 iliac bone biopsies Clin. Orthop. Relat. Res. 80 1971 147 154
    • (1971) Clin. Orthop. Relat. Res. , vol.80 , pp. 147-154
    • Meunier, P.1    Aaron, J.2    Edouard, C.3    Vignon, G.4
  • 17
    • 31544457103 scopus 로고    scopus 로고
    • Mechanisms of disease: Is osteoporosis the obesity of bone?
    • C.J. Rosen, and M.L. Bouxsein Mechanisms of disease: is osteoporosis the obesity of bone? Nat. Clin. Pract. Rheumatol. 2 2006 35 43
    • (2006) Nat. Clin. Pract. Rheumatol. , vol.2 , pp. 35-43
    • Rosen, C.J.1    Bouxsein, M.L.2
  • 19
    • 34547852256 scopus 로고    scopus 로고
    • Anemia of immobility: Caused by adipocyte accumulation in bone marrow
    • M.W. Payne, H.K. Uhthoff, and G. Trudel Anemia of immobility: caused by adipocyte accumulation in bone marrow Med. Hypotheses 69 2007 778 786
    • (2007) Med. Hypotheses , vol.69 , pp. 778-786
    • Payne, M.W.1    Uhthoff, H.K.2    Trudel, G.3
  • 20
    • 0032793068 scopus 로고    scopus 로고
    • Regulation of peroxisome proliferator-activated receptor gamma expression by adipocyte differentiation and determination factor 1/sterol regulatory element binding protein 1: Implications for adipocyte differentiation and metabolism
    • L. Fajas, K. Schoonjans, L. Gelman, J.B. Kim, J. Najib, G. Martin, J.C. Fruchart, M. Briggs, B.M. Spiegelman, and J. Auwerx Regulation of peroxisome proliferator-activated receptor gamma expression by adipocyte differentiation and determination factor 1/sterol regulatory element binding protein 1: implications for adipocyte differentiation and metabolism Mol. Cell Biol. 19 1999 5495 5503
    • (1999) Mol. Cell Biol. , vol.19 , pp. 5495-5503
    • Fajas, L.1    Schoonjans, K.2    Gelman, L.3    Kim, J.B.4    Najib, J.5    Martin, G.6    Fruchart, J.C.7    Briggs, M.8    Spiegelman, B.M.9    Auwerx, J.10
  • 21
    • 0038607705 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor-gamma inhibits the Runx2-mediated transcription of osteocalcin in osteoblasts
    • M.J. Jeon, J.A. Kim, S.H. Kwon, S.W. Kim, K.S. Park, S.W. Park, S.Y. Kim, and C.S. Shin Activation of peroxisome proliferator-activated receptor-gamma inhibits the Runx2-mediated transcription of osteocalcin in osteoblasts J. Biol. Chem. 278 2003 23270 23277
    • (2003) J. Biol. Chem. , vol.278 , pp. 23270-23277
    • Jeon, M.J.1    Kim, J.A.2    Kwon, S.H.3    Kim, S.W.4    Park, K.S.5    Park, S.W.6    Kim, S.Y.7    Shin, C.S.8
  • 22
    • 84899150663 scopus 로고    scopus 로고
    • Review of signaling pathways governing MSC osteogenic and adipogenic differentiation
    • A.W. James Review of signaling pathways governing MSC osteogenic and adipogenic differentiation Sci. Cairo 2013 2013 684736
    • (2013) Sci. Cairo , vol.2013 , pp. 684736
    • James, A.W.1
  • 23
    • 33646354409 scopus 로고    scopus 로고
    • Activation of CCAAT/enhancer-binding protein (C/EBP) alpha expression by C/EBP beta during adipogenesis requires a peroxisome proliferator-activated receptor-gamma-associated repression of HDAC1 at the C/ebp alpha gene promoter
    • Y. Zuo, L. Qiang, and S.R. Farmer Activation of CCAAT/enhancer-binding protein (C/EBP) alpha expression by C/EBP beta during adipogenesis requires a peroxisome proliferator-activated receptor-gamma-associated repression of HDAC1 at the C/ebp alpha gene promoter J. Biol. Chem. 281 2006 7960 7967
    • (2006) J. Biol. Chem. , vol.281 , pp. 7960-7967
    • Zuo, Y.1    Qiang, L.2    Farmer, S.R.3
  • 24
    • 0037330414 scopus 로고    scopus 로고
    • PPARgamma agonists in the treatment of type II diabetes: Is increased fatness commensurate with long-term efficacy?
    • T.M. Larsen, S. Toubro, and A. Astrup PPARgamma agonists in the treatment of type II diabetes: is increased fatness commensurate with long-term efficacy? Int. J. Obes. Relat. Metab. Disord. 27 2003 147 161
    • (2003) Int. J. Obes. Relat. Metab. Disord. , vol.27 , pp. 147-161
    • Larsen, T.M.1    Toubro, S.2    Astrup, A.3
  • 25
    • 33645863768 scopus 로고    scopus 로고
    • Transcriptional regulation of metabolism
    • B. Desvergne, L. Michalik, and W. Wahli Transcriptional regulation of metabolism Physiol. Rev. 86 2006 465 514
    • (2006) Physiol. Rev. , vol.86 , pp. 465-514
    • Desvergne, B.1    Michalik, L.2    Wahli, W.3
  • 26
    • 71649093576 scopus 로고    scopus 로고
    • Regulation of osteoblast and adipocyte differentiation from human mesenchymal stem cells by conjugated linoleic acid
    • I.D. Platt, and A. El-Sohemy Regulation of osteoblast and adipocyte differentiation from human mesenchymal stem cells by conjugated linoleic acid J. Nutr. Biochem. 20 2009 956 964
    • (2009) J. Nutr. Biochem. , vol.20 , pp. 956-964
    • Platt, I.D.1    El-Sohemy, A.2
  • 28
    • 78349247846 scopus 로고    scopus 로고
    • Melatonin inhibits adipogenesis and enhances osteogenesis of human mesenchymal stem cells by suppressing PPARgamma expression and enhancing Runx2 expression
    • L. Zhang, P. Su, C. Xu, C. Chen, A. Liang, K. Du, Y. Peng, and D. Huang Melatonin inhibits adipogenesis and enhances osteogenesis of human mesenchymal stem cells by suppressing PPARgamma expression and enhancing Runx2 expression J. Pineal Res. 49 2010 364 372
    • (2010) J. Pineal Res. , vol.49 , pp. 364-372
    • Zhang, L.1    Su, P.2    Xu, C.3    Chen, C.4    Liang, A.5    Du, K.6    Peng, Y.7    Huang, D.8
  • 29
    • 84865609750 scopus 로고    scopus 로고
    • Curcumin increases rat mesenchymal stem cell osteoblast differentiation but inhibits adipocyte differentiation
    • Q. Gu, Y. Cai, C. Huang, Q. Shi, and H. Yang Curcumin increases rat mesenchymal stem cell osteoblast differentiation but inhibits adipocyte differentiation Pharmacogn. Mag. 8 2012 202 208
    • (2012) Pharmacogn. Mag. , vol.8 , pp. 202-208
    • Gu, Q.1    Cai, Y.2    Huang, C.3    Shi, Q.4    Yang, H.5
  • 30
    • 0036472327 scopus 로고    scopus 로고
    • Retinoic acid activation of the ERK pathway is required for embryonic stem cell commitment into the adipocyte lineage
    • F. Bost, L. Caron, I. Marchetti, C. Dani, Y. Le Marchand-Brustel, and B. Binetruy Retinoic acid activation of the ERK pathway is required for embryonic stem cell commitment into the adipocyte lineage Biochem. J. 361 2002 621 627
    • (2002) Biochem. J. , vol.361 , pp. 621-627
    • Bost, F.1    Caron, L.2    Marchetti, I.3    Dani, C.4    Le Marchand-Brustel, Y.5    Binetruy, B.6
  • 31
    • 84881604578 scopus 로고    scopus 로고
    • Shikonin suppresses ERK 1/2 phosphorylation during the early stages of adipocyte differentiation in 3T3-L1 cells
    • S.Y. Gwon, J.Y. Ahn, C.H. Jung, B.K. Moon, and T.Y. Ha Shikonin suppresses ERK 1/2 phosphorylation during the early stages of adipocyte differentiation in 3T3-L1 cells BMC Complement. Altern. Med. 13 2013 207
    • (2013) BMC Complement. Altern. Med. , vol.13 , pp. 207
    • Gwon, S.Y.1    Ahn, J.Y.2    Jung, C.H.3    Moon, B.K.4    Ha, T.Y.5
  • 32
    • 14544298335 scopus 로고    scopus 로고
    • The role of MAPKs in adipocyte differentiation and obesity
    • F. Bost, M. Aouadi, L. Caron, and B. Binetruy The role of MAPKs in adipocyte differentiation and obesity Biochimie 87 2005 51 56
    • (2005) Biochimie , vol.87 , pp. 51-56
    • Bost, F.1    Aouadi, M.2    Caron, L.3    Binetruy, B.4
  • 33
    • 0035853804 scopus 로고    scopus 로고
    • DNA synthesis and mitotic clonal expansion is not a required step for 3T3-L1 preadipocyte differentiation into adipocytes
    • Z. Qiu, Y. Wei, N. Chen, M. Jiang, J. Wu, and K. Liao DNA synthesis and mitotic clonal expansion is not a required step for 3T3-L1 preadipocyte differentiation into adipocytes J. Biol. Chem. 276 2001 11988 11995
    • (2001) J. Biol. Chem. , vol.276 , pp. 11988-11995
    • Qiu, Z.1    Wei, Y.2    Chen, N.3    Jiang, M.4    Wu, J.5    Liao, K.6
  • 34
    • 39049117924 scopus 로고    scopus 로고
    • Effect of sesamol on diabetes-associated cognitive decline in rats
    • A. Kuhad, and K. Chopra Effect of sesamol on diabetes-associated cognitive decline in rats Exp. Brain Res. 185 2008 411 420
    • (2008) Exp. Brain Res. , vol.185 , pp. 411-420
    • Kuhad, A.1    Chopra, K.2
  • 35
    • 84881509057 scopus 로고    scopus 로고
    • Protective effect of 3,4-methylenedioxyphenol (sesamol) on stress-related mucosal disease in rats
    • D.Z. Hsu, Y.W. Chen, P.Y. Chu, S. Periasamy, and M.Y. Liu Protective effect of 3,4-methylenedioxyphenol (sesamol) on stress-related mucosal disease in rats Biomed. Res. Int. 2013 2013 481827
    • (2013) Biomed. Res. Int. , vol.2013 , pp. 481827
    • Hsu, D.Z.1    Chen, Y.W.2    Chu, P.Y.3    Periasamy, S.4    Liu, M.Y.5
  • 36
    • 0029883886 scopus 로고    scopus 로고
    • Antioxidative effect of sesamol and related compounds on lipid peroxidation
    • M. Uchida, S. Nakajin, S. Toyoshima, and M. Shinoda Antioxidative effect of sesamol and related compounds on lipid peroxidation Biol. Pharm. Bull. 19 1996 623 626
    • (1996) Biol. Pharm. Bull. , vol.19 , pp. 623-626
    • Uchida, M.1    Nakajin, S.2    Toyoshima, S.3    Shinoda, M.4
  • 37
    • 14844282050 scopus 로고    scopus 로고
    • Regulation of PPARgamma activity during adipogenesis
    • S.R. Farmer Regulation of PPARgamma activity during adipogenesis Int. J. Obes. Lond. 29 Suppl. 1 2005 S13 S16
    • (2005) Int. J. Obes. Lond. , vol.29 , pp. S13-S16
    • Farmer, S.R.1
  • 39
    • 0033083803 scopus 로고    scopus 로고
    • Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity
    • Z. Wu, E.D. Rosen, R. Brun, S. Hauser, G. Adelmant, A.E. Troy, C. McKeon, G.J. Darlington, and B.M. Spiegelman Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity Mol. Cell 3 1999 151 158
    • (1999) Mol. Cell , vol.3 , pp. 151-158
    • Wu, Z.1    Rosen, E.D.2    Brun, R.3    Hauser, S.4    Adelmant, G.5    Troy, A.E.6    McKeon, C.7    Darlington, G.J.8    Spiegelman, B.M.9
  • 40
    • 35548952832 scopus 로고    scopus 로고
    • Effect of deficiency in SREBP cleavage-activating protein on lipid metabolism during intermittent hypoxia
    • J. Li, A. Nanayakkara, J. Jun, V. Savransky, and V.Y. Polotsky Effect of deficiency in SREBP cleavage-activating protein on lipid metabolism during intermittent hypoxia Physiol. Genom. 31 2007 273 280
    • (2007) Physiol. Genom. , vol.31 , pp. 273-280
    • Li, J.1    Nanayakkara, A.2    Jun, J.3    Savransky, V.4    Polotsky, V.Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.