Nrf2 antioxidant defense is involved in survival signaling elicited by 27-hydroxycholesterol in human promonocytic cells

Free Radical Biology and Medicine

Volumn 91, Issue , 2016, Pages 93-104

  Vurusaner, Beyza ^a   Gamba, Paola ^b   Gargiulo, Simona ^b   Testa, Gabriella ^b   Staurenghi, Erica ^b   Leonarduzzi, Gabriella ^b   Poli, Giuseppe ^b   Basaga, Huveyda ^a  

^a SABANCI UNIVERSITY   (Turkey)

^b UNIVERSITY OF TURIN   (Italy)

Author keywords

27 Hydroxycholesterol; Nrf2; Oxysterols; ROS; Survival signaling

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 26 HYDROXYCHOLESTEROL; ENZYME; HEME OXYGENASE 1; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; PROTEIN NQO 1; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; 27-HYDROXYCHOLESTEROL; CHOLESTEROL DERIVATIVE; HMOX1 PROTEIN, HUMAN; NFE2L2 PROTEIN, HUMAN; NQO1 PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 3 KINASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

ARTICLE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MACROPHAGE; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; U937 CELL LINE; UPREGULATION; ACTIVE TRANSPORT; APOPTOSIS; CELL LINE; CELL SURVIVAL; DRUG EFFECTS; ENZYME INDUCTION; GENETICS; METABOLISM; MONOCYTE MACROPHAGE PRECURSOR CELL;

ACTIVE TRANSPORT, CELL NUCLEUS; APOPTOSIS; CELL LINE; CELL SURVIVAL; ENZYME INDUCTION; HEME OXYGENASE-1; HUMANS; HYDROXYCHOLESTEROLS; MAP KINASE SIGNALING SYSTEM; MONOCYTE-MACROPHAGE PRECURSOR CELLS; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES;

EID: 84950243661     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.12.007     Document Type: Article

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