Effects of SOX2 on proliferation, migration and adhesion of human dental pulp stem cells

PLoS ONE

Volumn 10, Issue 10, 2015, Pages

  Liu, Pengfei ^a,b   Cai, Jinglei ^b   Dong, Delu ^a   Chen, Yaoyu ^a,b   Liu, Xiaobo ^a,b   Wang, Yi ^a   Zhou, Yulai ^a  

^a JILIN UNIVERSITY   (China)

^b GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLECYSTOKININ OCTAPEPTIDE; FIBRONECTIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SOX2; SOX2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR SOX;

ARTICLE; CELL ADHESION; CELL CYCLE; CELL FUNCTION; CELL ISOLATION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; FILTERS AND MEMBRANES; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; MICROARRAY ANALYSIS; MOLAR TOOTH; POLYMERASE CHAIN REACTION; RETROVIRUS INFECTION; SIGNAL TRANSDUCTION; STEM CELL; TISSUE ENGINEERING; TOOTH DISEASE; TOOTH PULP; UPREGULATION; WESTERN BLOTTING; ADULT STEM CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL MOTION; CYTOLOGY; GENETICS; METABOLISM; PHYSIOLOGY;

ADULT STEM CELLS; CELL ADHESION; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; DENTAL PULP; GENE EXPRESSION; HUMANS; SOXB1 TRANSCRIPTION FACTORS;

EID: 84949844908     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0141346     Document Type: Article

References (46)

1. Lewis S. Stem cells: Sending cells back in time. Nat Rev Neurosci. 2013; 14(2):78. doi: 10.1038/nrn3432 PMID: 23299058.
2. Trounson A, Thakar RG, Lomax G, Gibbons D. Clinical trials for stem cell therapies. BMC Med. 2011; 9:52. doi: 10.1186/1741-7015-9-52 PMID: 21569277; PubMed Central PMCID: PMC3098796.
3. Hendriks S, Dancet EAF, van Pelt AMM, Hamer G, Repping S. Artificial gametes: a systematic review of biological progress towards clinical application. Hum Reprod Update. 2015; 21(3):285-96. doi: 10.1093/humupd/dmv001 PMID: WOS: 000354792800001.
4. Pisciotta A, Carnevale G, Meloni S, Riccio M, De Biasi S, Gibellini L, et al. Human dental pulp stem cells (hDPSCs): isolation, enrichment and comparative differentiation of two sub-populations. BMC developmental biology. 2015; 15:14. doi: 10.1186/s12861-015-0065-x PMID: 25879198; PubMed Central PMCID: PMC4377026.
5. d'Aquino R, De Rosa A, Laino G, Caruso F, Guida L, Rullo R, et al.Human dental pulp stem cells: from biology to clinical applications. Journal of experimental zoology Part B, Molecular and developmental evolution. 2009; 312B(5):408-15. doi: 10.1002/jez.b.21263 PMID: 19065566.
6. Goldberg M, Smith AJ. Cells and extracellular matrices of dentin and pulp: A biological basis for repair and tissue engineering. Crit Rev Oral Biol M. 2004; 15(1):13-27. PMID: WOS: 000226792300003.
7. Gronthos S, Mankani M, Brahim J, Robey PG, Shi S. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America. 2000; 97(25):13625-30. doi: 10.1073/pnas.240309797 PMID: 11087820; PubMed Central PMCID: PMC17626.
8. Tatullo M, Marrelli M, Shakesheff KM, White LJ. Dental pulp stem cells: function, isolation and applications in regenerative medicine. Journal of tissue engineering and regenerative medicine. 2014. doi: 10.1002/term.1899 PMID: 24850632.
9. Paino F, La Noce M, Tirino V, Naddeo P, Desiderio V, Pirozzi G, et al. Histone deacetylase inhibition with valproic acid downregulates osteocalcin gene expression in human dental pulp stem cells and osteoblasts: evidence for HDAC2 involvement. Stem cells. 2014; 32(1):279-89. doi: 10.1002/stem.1544 PMID: 24105979; PubMed Central PMCID: PMC3963447.
10. La Noce M, Paino F, Spina A, Naddeo P, Montella R, Desiderio V, et al. Dental pulp stem cells: state of the art and suggestions for a true translation of research into therapy. Journal of dentistry. 2014; 42 (7):761-8. doi: 10.1016/j.jdent.2014.02.018 PMID: 24589847.
11. Liu J, Yu F, Sun Y, Jiang B, Zhang W, Yang J, et al. Concise reviews: Characteristics and potential applications of human dental tissue-derived mesenchymal stem cells. Stem cells. 2015; 33(3):627-38. doi: 10.1002/stem.1909 PMID: 25447379.
12. Tirino V, Paino F, d'Aquino R, Desiderio V, De Rosa A, Papaccio G. Methods for the Identification, Characterization and Banking of Human DPSCs: Current Strategies and Perspectives. Stem Cell Rev Rep. 2011; 7(3):608-15. doi: 10.1007/s12015-011-9235-9 PMID: WOS: 000292835000013.
13. Conde MCM, Nedel F, Campos VF, Smith AJ, Nor JE, Demarco FF, et al. Odontoblast RNA stability in different temperature-based protocols for tooth storage. International endodontic journal. 2012; 45 (3):266-72. doi: 10.1111/j.1365-2591.2011.01971.x PMID: WOS: 000299545500008.
14. Liu L, Wu L, Wei X, Ling J. Induced overexpression of Oct4A in human dental pulp cells enhances pluripotency and multilineage differentiation capability. Stem cells and development. 2015; 24(8):962-72. doi: 10.1089/scd.2014.0388 PMID: 25422984.
15. Jayaraman P, Govindasamy V, Gnanasegaran N, Kunasekaran W, Vasanthan P, Musa S, et al. Expression patterns of immune genes in long-term cultured dental stem cells. Clinical oral investigations. 2015. doi: 10.1007/s00784-015-1497-1 PMID: 26048030.
16. Han SM, Han SH, Coh YR, Jang G, Chan Ra J, Kang SK, et al. Enhanced proliferation and differentiation of Oct4- and Sox2-overexpressing human adipose tissue mesenchymal stem cells. Experimental & molecular medicine. 2014; 46:e101. doi: 10.1038/emm.2014.28 PMID: 24946789; PubMed Central PMCID: PMC4081551.
17. Liu L, Wei X, Ling J, Wu L, Xiao Y. Expression pattern of Oct-4, Sox2, and c-Myc in the primary culture of human dental pulp derived cells. Journal of endodontics. 2011; 37(4):466-72. doi: 10.1016/j.joen.2010.12.012 PMID: 21419292.
18. Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006; 126(4):663-76. doi: 10.1016/j.cell.2006.07.024 PMID: 16904174.
19. Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell. 2007; 131(5):861-72. doi: 10.1016/j.cell.2007.11.019 PMID: 18035408.
20. Cai J, Li W, Su H, Qin D, Yang J, Zhu F, et al. Generation of human induced pluripotent stem cells from umbilical cord matrix and amniotic membrane mesenchymal cells. The Journal of biological chemistry. 2010; 285(15):11227-34. doi: 10.1074/jbc.M109.086389 PMID: 20139068; PubMed Central PMCID: PMC2857000.
21. Esteban MA, Wang T, Qin B, Yang J, Qin D, Cai J, et al. Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. Cell Stem Cell. 2010; 6(1):71-9. doi: 10.1016/j.stem.2009.12.001 PMID: 20036631.
22. Yan X, Qin H, Qu C, Tuan RS, Shi S, Huang GT. iPS cells reprogrammed from human mesenchymal-like stem/progenitor cells of dental tissue origin. Stem cells and development. 2010; 19(4):469-80. doi: 10.1089/scd.2009.0314 PMID: 19795982; PubMed Central PMCID: PMC2851830.
23. Beltrao-Braga PC, Pignatari GC, Maiorka PC, Oliveira NA, Lizier NF, Wenceslau CV, et al. Feeder-free derivation of induced pluripotent stem cells from human immature dental pulp stem cells. Cell transplantation. 2011; 20(11-12):1707-19. doi: 10.3727/096368911X566235 PMID: 21457612.
24. Tamaoki N, Takahashi K, Tanaka T, Ichisaka T, Aoki H, Takeda-Kawaguchi T, et al. Dental pulp cells for induced pluripotent stem cell banking. J Dent Res. 2010; 89(8):773-8. doi: 10.1177/0022034510366846 PMID: 20554890.
25. Masui S, Nakatake Y, Toyooka Y, Shimosato D, Yagi R, Takahashi K, et al. Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells. Nature cell biology. 2007; 9 (6):625-35. doi: 10.1038/ncb1589 PMID: 17515932.
26. Kopp JL, Ormsbee BD, Desler M, Rizzino A. Small increases in the level of Sox2 trigger the differentiation of mouse embryonic stem cells. Stem cells. 2008; 26(4):903-11. doi: 10.1634/stemcells.2007-0951 PMID: 18238855.
27. Qin Y, Zhou C, Wang N, Yang H, Gao WQ. Conversion of Adipose Tissue-Derived Mesenchymal Stem Cells to Neural Stem Cell-Like Cells by a Single Transcription Factor, Sox2. Cellular reprogramming. 2015; 17(3):221-6. doi: 10.1089/cell.2015.0001 PMID: 26053521.
28. Yoon DS, Kim YH, Jung HS, Paik S, Lee JW. Importance of Sox2 in maintenance of cell proliferation and multipotency of mesenchymal stem cells in low-density culture. Cell proliferation. 2011; 44(5):428-40. doi: 10.1111/j.1365-2184.2011.00770.x PMID: 21951286.
29. Liu TM, Wu YN, Guo XM, Hui JH, Lee EH, Lim B. Effects of ectopic Nanog and Oct4 overexpression on mesenchymal stem cells. Stem cells and development. 2009; 18(7):1013-22. doi: 10.1089/scd.2008.0335 PMID: 19102659; PubMed Central PMCID: PMC3190294.
30. Yang N, Hui L, Wang Y, Yang H, Jiang X. Overexpression of SOX2 promotes migration, invasion, and epithelial-mesenchymal transition through the Wnt/beta-catenin pathway in laryngeal cancer Hep-2 cells. Tumour biology: the journal of the International Society for Oncodevelopmental Biology and Medicine. 2014; 35(8):7965-73. doi: 10.1007/s13277-014-2045-3 PMID: 24833089.
31. Go MJ, Takenaka C, Ohgushi H. Forced expression of Sox2 or Nanog in human bone marrow derived mesenchymal stem cells maintains their expansion and differentiation capabilities. Experimental cell research. 2008; 314(5):1147-54. doi: 10.1016/j.yexcr.2007.11.021 PMID: WOS: 000253752300020.
32. Qin Z, Li Y, Li Y, Liu G. Tumor Necrosis Factor Alpha Stimulates Proliferation of Dental Pulp Stem Cells via Akt/Glycogen Synthase Kinase-3beta/Cyclin D1 Signaling Pathway. Journal of endodontics. 2015. doi: 10.1016/j.joen.2015.02.020 PMID: 25843750.
33. Liu P, Feng Y, Dong C, Yang D, Li B, Chen X, et al. Administration of BMSCs with Muscone in Rats with Gentamicin-Induced AKI Improves Their Therapeutic Efficacy. PloS one. 2014; 9(5):e97123. doi: 10.1371/journal.pone.0097123 PMID: 24824427
34. Liu P, Feng Y, Dong C, Liu D, Wu X, Wu H, et al. Study on therapeutic action of bone marrow derived mesenchymal stem cell combined with vitamin E against acute kidney injury in rats. Life sciences. 2013; 92(14-16):829-37. doi: 10.1016/j.lfs.2013.02.016 PMID: 23499556.
35. Majchrzak K, Lo Re D, Gajewska M, Bulkowska M, Homa A, Pawlowski K, et al. Migrastatin analogues inhibit canine mammary cancer cell migration and invasion. PloS one. 2013; 8(10):e76789. doi: 10.1371/journal.pone.0076789 PMID: 24116159; PubMed Central PMCID: PMC3792885.
36. Zhang W, Mao YQ, Wang H, Yin WJ, Zhu SX, Wang WC. MiR-124 suppresses cell motility and adhesion by targeting talin 1 in prostate cancer cells. Cancer cell international. 2015; 15:49. doi: 10.1186/ s12935-015-0189-x PMID: 25969668; PubMed Central PMCID: PMC4427999.
37. Matsuzawa M, Arai C, Nomura Y, Murata T, Yamakoshi Y, Oida S, et al. Periostin of human periodontal ligament fibroblasts promotes migration of human mesenchymal stem cell through the alphavbeta3 integrin/FAK/PI3K/Akt pathway. Journal of periodontal research. 2015. doi: 10.1111/jre.12277 PMID: 25900259.
38. Gao F, Hu X, Xie X, Liu X, Wang J. Heat shock protein 90 stimulates rat mesenchymal stem cell migration via PI3K/Akt and ERK1/2 pathways. Cell biochemistry and biophysics. 2015; 71(1):481-9. doi: 10.1007/s12013-014-0228-6 PMID: 25287672.
39. Liu N, Tian J, Cheng J, Zhang J. Migration of CXCR4 gene-modified bone marrow-derived mesenchymal stem cells to the acute injured kidney. J Cell Biochem. 2013; 114(12):2677-89. doi: 10.1002/jcb.24615 PMID: 23794207.
40. Fan YX, Gu CH, Zhang YL, Zhong BS, Wang LZ, Zhou ZR, et al. Oct4 and Sox2 overexpression improves the proliferation and differentiation of bone mesenchymal stem cells in Xiaomeishan porcine. Genetics and molecular research: GMR. 2013; 12(4):6067-79. doi: 10.4238/2013.December.2.5 PMID: 24338401.
41. Hutz K, Mejias-Luque R, Farsakova K, Ogris M, Krebs S, Anton M, et al. The stem cell factor SOX2 regulates the tumorigenic potential in human gastric cancer cells. Carcinogenesis. 2014; 35(4):942-50. doi: 10.1093/carcin/bgt410 PMID: 24325912.
42. Lin F, Lin P, Zhao D, Chen Y, Xiao L, Qin W, et al. Sox2 targets cyclinE, p27 and survivin to regulate androgen-independent human prostate cancer cell proliferation and apoptosis. Cell proliferation. 2012; 45(3):207-16. doi: 10.1111/j.1365-2184.2012.00812.x PMID: 22469032.
43. Wang X, Ji X, Chen J, Yan D, Zhang Z, Wang Q, et al. SOX2 enhances the migration and invasion of ovarian cancer cells via Src kinase. PloS one. 2014; 9(6):e99594. doi: 10.1371/journal.pone.0099594 PMID: 24937695; PubMed Central PMCID: PMC4061006.
44. Yang N, Hui L, Wang Y, Yang H, Jiang X. SOX2 promotes the migration and invasion of laryngeal cancer cells by induction of MMP-2 via the PI3K/Akt/mTOR pathway. Oncology reports. 2014; 31(6):2651-9. doi: 10.3892/or.2014.3120 PMID: 24700142.
45. Cheng K, Rai P, Plagov A, Lan X, Kumar D, Salhan D, et al. Transplantation of bone marrow-derived MSCs improves cisplatinum-induced renal injury through paracrine mechanisms. Exp Mol Pathol. 2013; 94(3):466-73. doi: 10.1016/j.yexmp.2013.03.002 PMID: 23534987; PubMed Central PMCID: PMC3647016.
46. Galler KM, Widbiller M, Buchalla W, Eidt A, Hiller KA, Hoffer P, et al. EDTA conditioning of dentine promotes adhesion, migration and differentiation of dental pulp stem cells. International endodontic journal. 2015. doi: 10.1111/iej.12492 PMID: 26114662.