SOX2 promotes the migration and invasion of laryngeal cancer cells by induction of MMP-2 via the PI3K/Akt/mTOR pathway

Oncology Reports

Volumn 31, Issue 6, 2014, Pages 2651-2659

  Yang, Ning ^a   Hui, Lian ^a   Wang, Yan ^a   Yang, Huijun ^a   Jiang, Xuejun ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Cell invasion; Laryngeal cancer; Matrix metalloproteinase 2; PI3K; SOX2

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; GELATINASE A; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SOX2; MATRIX METALLOPROTEINASE INHIBITOR; MTOR PROTEIN, HUMAN; ONCOPROTEIN; SOX2 PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE; TRANSCRIPTION FACTOR SOX;

ARTICLE; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME REGULATION; HEP 2 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; LARYNGEAL CANCER CELL LINE; LARYNX SQUAMOUS CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; TUMOR PROMOTION; UPREGULATION; BIOSYNTHESIS; CELL MOTION; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GENETICS; HEPG2 CELL LINE; LARYNX TUMOR; METABOLISM; PATHOLOGY; TUMOR INVASION;

CELL MOVEMENT; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HEP G2 CELLS; HUMANS; LARYNGEAL NEOPLASMS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE INHIBITORS; NEOPLASM INVASIVENESS; ONCOGENE PROTEIN V-AKT; PHOSPHATIDYLINOSITOL 3-KINASES; SOXB1 TRANSCRIPTION FACTORS; TOR SERINE-THREONINE KINASES;

EID: 84902149646     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2014.3120     Document Type: Article

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