Neurodegeneration in frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9orf72 is linked to TDP-43 pathology and not associated with aggregated forms of dipeptide repeat proteins

Neuropathology and Applied Neurobiology

Volumn 42, Issue 3, 2016, Pages 242-254

  Davidson, Y ^a   Robinson, A C ^a   Liu, X ^a,b   Wu, D ^a,b   Troakes, C ^c   Rollinson, S ^a   Masuda Suzukake, M ^d   Suzuki, G ^d   Nonaka, T ^d   Shi, J ^b   Tian, J ^b   Hamdalla, H ^e   Ealing, J ^e   Richardson, A ^e   Jones, M ^e   Pickering Brown, S ^a   Snowden, J S ^a,e   Hasegawa, M ^d   Mann, D M A ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^e HOPE HOSPITAL   (United Kingdom)

Author keywords

C9orf72; Dipeptide repeat proteins; Frontotemporal lobar degeneration; Motor neurone disease; TDP 43

Indexed keywords

CARRIER PROTEINS AND BINDING PROTEINS; DIPEPTIDE REPEAT PROTEIN; POLY GA PROTEIN; POLY GP PROTEIN; POLY GR PROTEIN; POLY PA PROTEIN; POLY PR PROTEIN; PROTEIN ANTIBODY; UNCLASSIFIED DRUG; C9ORF72 PROTEIN, HUMAN; DIPEPTIDE; DNA BINDING PROTEIN; PROTEIN; REPETITIVE DNA; TDP-43 PROTEIN, HUMAN;

ANTERIOR HORN CELL; ANTIBODY DETECTION; ARTICLE; BRAIN CORTEX; C9ORF72 GENE; CELL INCLUSION; CEREBELLUM; CLINICAL ARTICLE; FRONTAL VARIANT FRONTOTEMPORAL DEMENTIA; GENE; GRANULE CELL; HIPPOCAMPUS; HUMAN; MOTOR NEURON DISEASE; NERVE DEGENERATION; NEUROPATHOLOGY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SPINAL CORD; TDP 43 PROTEINOPATHY; THALAMUS; AGED; FEMALE; FRONTOTEMPORAL DEMENTIA; GENETICS; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; MIDDLE AGED; NERVE CELL; PATHOLOGY;

AGED; DIPEPTIDES; DNA REPEAT EXPANSION; DNA-BINDING PROTEINS; FEMALE; FRONTOTEMPORAL LOBAR DEGENERATION; HUMANS; IMMUNOHISTOCHEMISTRY; INCLUSION BODIES; MALE; MIDDLE AGED; MOTOR NEURON DISEASE; NERVE DEGENERATION; NEURONS; PROTEINS;

EID: 84949665218     PISSN: 03051846     EISSN: 13652990     Source Type: Journal    
DOI: 10.1111/nan.12292     Document Type: Article

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