Activation of AKT1/GSK-3β/β-Catenin–TRIM11/Survivin Pathway by Novel GSK-3β Inhibitor Promotes Neuron Cell Survival: Study in Differentiated SH-SY5Y Cells in OGD Model

Molecular Neurobiology

Volumn 53, Issue 10, 2016, Pages 6716-6729

  Darshit, B S ^a   Ramanathan, M ^a  

^a PSG COLLEGE OF PHARMACY   (India)

Author keywords

Apoptosis; Glycogen synthase kinase 3 (GSK 3 ); Ischemia; Neuroprotection; Purine; Catenin

Indexed keywords

1 (4 METHOXYBENZYL) 3 (5 NITRO 2 THIAZOLYL)UREA; AKT1 PROTEIN; BETA CATENIN; CASPASE 3; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; GLYCOGEN SYNTHASE KINASE 3BETA INHIBITOR; LACTATE DEHYDROGENASE; NEUROGENIN 1; NEUROMODULIN; NEURONAL DIFFERENTIATION 2; PEPTIDES AND PROTEINS; RETINOIC ACID; SURVIVIN; TRIPARTITE MOTIF CONTAINING 11 PROTEIN; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; BIRC5 PROTEIN, HUMAN; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3BETA; INHIBITOR OF APOPTOSIS PROTEIN; OXYGEN; PROTEIN KINASE B; PROTEIN KINASE INHIBITOR; TRIM11 PROTEIN, HUMAN; TRIPARTITE MOTIF PROTEIN; UBIQUITIN PROTEIN LIGASE;

APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; GAP43 GENE; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MOLECULAR MODEL; MOLECULE; MTT ASSAY; NERVE CELL; NEUROBLASTOMA CELL LINE; NEUROD2 GENE; NEUROPROTECTION; NGN1 GENE; OXYGEN AND GLUCOSE DEPRIVATION MODEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SH SY5Y CELL LINE; SIGNAL TRANSDUCTION; TRIM11 GENE; UPREGULATION; BIOLOGICAL MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; METABOLISM; PATHOLOGY; TIME FACTOR; TUMOR CELL LINE;

APOPTOSIS; BETA CATENIN; BIOMARKERS; CASPASE 3; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL SURVIVAL; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3 BETA; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; L-LACTATE DEHYDROGENASE; MODELS, BIOLOGICAL; NEURONS; NEUROPROTECTION; OXYGEN; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TIME FACTORS; TRIPARTITE MOTIF PROTEINS; UBIQUITIN-PROTEIN LIGASES; UP-REGULATION;

EID: 84949655924     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-015-9598-z     Document Type: Article

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