메뉴 건너뛰기




Volumn 6, Issue NOV, 2015, Pages

Macrophages during the fibrotic process: M2 as friend and foe

Author keywords

Cell metabolism; Fibrosis; Macrophage activation; Myofibroblasts; Polarization

Indexed keywords

ARGINASE; BONE MORPHOGENETIC PROTEIN; INTERLEUKIN 10; SCATTER FACTOR; TRANSFORMING GROWTH FACTOR BETA;

EID: 84949635133     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2015.00602     Document Type: Short Survey
Times cited : (341)

References (85)
  • 1
    • 28544446111 scopus 로고    scopus 로고
    • Monocyte and macrophage heterogeneity
    • Gordon S, Taylor PR. Monocyte and macrophage heterogeneity. Nat Rev Immunol (2005) 5(12):953-64. doi: 10.1038/nri1733.
    • (2005) Nat Rev Immunol , vol.5 , Issue.12 , pp. 953-964
    • Gordon, S.1    Taylor, P.R.2
  • 2
    • 84857883847 scopus 로고    scopus 로고
    • Macrophage plasticity and polarization: in vivo veritas
    • Sica A, Mantovani A. Macrophage plasticity and polarization: in vivo veritas. J Clin Invest (2012) 122(3):787-95. doi:10.1172/JCI59643.
    • (2012) J Clin Invest , vol.122 , Issue.3 , pp. 787-795
    • Sica, A.1    Mantovani, A.2
  • 3
    • 77953881058 scopus 로고    scopus 로고
    • Macrophages and immunologic inflammation of the kidney
    • Duffield JS. Macrophages and immunologic inflammation of the kidney. Semin Nephrol (2010) 30(3):234-54. doi:10.1016/j.semnephrol.2010.03.003.
    • (2010) Semin Nephrol , vol.30 , Issue.3 , pp. 234-254
    • Duffield, J.S.1
  • 4
    • 77954961992 scopus 로고    scopus 로고
    • Macrophages: master regulators of inflammation and fibrosis
    • Wynn TA, Barron L. Macrophages: master regulators of inflammation and fibrosis. Semin Liver Dis (2010) 30(3):245-57. doi:10.1055/s-0030-1255354.
    • (2010) Semin Liver Dis , vol.30 , Issue.3 , pp. 245-257
    • Wynn, T.A.1    Barron, L.2
  • 5
    • 80052378182 scopus 로고    scopus 로고
    • The historical milestones in the understanding of leukocyte biology initiated by Elie Metchnikoff
    • Cavaillon JM. The historical milestones in the understanding of leukocyte biology initiated by Elie Metchnikoff. J Leukoc Biol (2011) 90(3):413-24. doi:10.1189/jlb.0211094.
    • (2011) J Leukoc Biol , vol.90 , Issue.3 , pp. 413-424
    • Cavaillon, J.M.1
  • 6
    • 76249095169 scopus 로고    scopus 로고
    • Development of monocytes, macrophages, and dendritic cells
    • Geissmann F, Manz MG, Jung S, Sieweke MH, Merad M, Ley K. Development of monocytes, macrophages, and dendritic cells. Science (2010) 327(5966):656-61. doi:10.1126/science.1178331.
    • (2010) Science , vol.327 , Issue.5966 , pp. 656-661
    • Geissmann, F.1    Manz, M.G.2    Jung, S.3    Sieweke, M.H.4    Merad, M.5    Ley, K.6
  • 7
    • 84876800337 scopus 로고    scopus 로고
    • Macrophage biology in development, homeostasis and disease
    • Wynn TA, Chawla A. Macrophage biology in development, homeostasis and disease. Nature (2013) 496(7446):445-55. doi:10.1038/nature12034.
    • (2013) Nature , vol.496 , Issue.7446 , pp. 445-455
    • Wynn, T.A.1    Chawla, A.2
  • 8
    • 84926656185 scopus 로고    scopus 로고
    • Ontogeny and polarization of macrophages in inflammation: blood monocytes versus tissue macrophages
    • Dey A, Allen J, Hankey-Giblin PA. Ontogeny and polarization of macrophages in inflammation: blood monocytes versus tissue macrophages. Front Immunol (2014) 5:683. doi:10.3389/fimmu.2014.00683.
    • (2014) Front Immunol , vol.5 , pp. 683
    • Dey, A.1    Allen, J.2    Hankey-Giblin, P.A.3
  • 9
    • 84934283265 scopus 로고    scopus 로고
    • Revisiting mouse peritoneal macrophages: heterogeneity, development, and function
    • Cassado Ados A, D'Império Lima MR, Bortoluci KR. Revisiting mouse peritoneal macrophages: heterogeneity, development, and function. Front Immunol (2015) 6:225. doi:10.3389/fimmu.2015.00225.
    • (2015) Front Immunol , vol.6 , pp. 225
    • Cassado Ados, A.1    D'Império Lima, M.R.2    Bortoluci, K.R.3
  • 10
    • 0034049748 scopus 로고    scopus 로고
    • Origins and functions of phagocytes in the embryo
    • Lichanska AM, Hume DA. Origins and functions of phagocytes in the embryo. Exp Hematol (2000) 28(6):601-11. doi:10.1016/S0301-472X(00)00157-0.
    • (2000) Exp Hematol , vol.28 , Issue.6 , pp. 601-611
    • Lichanska, A.M.1    Hume, D.A.2
  • 11
    • 0033988290 scopus 로고    scopus 로고
    • Developmental derivation of embryonic and adult macrophages
    • Shepard JL, Zon LI. Developmental derivation of embryonic and adult macrophages. Curr Opin Hematol (2000) 7(1):3-8. doi:10.1097/00062752-200001000-00002.
    • (2000) Curr Opin Hematol , vol.7 , Issue.1 , pp. 3-8
    • Shepard, J.L.1    Zon, L.I.2
  • 12
    • 84859508307 scopus 로고    scopus 로고
    • A lineage of myeloid cells independent of Myb and hematopoietic stem cells
    • Schulz C, Gomez Perdiguero E. A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science (2012) 336(6077):86-90. doi:10.1126/science.1219179.
    • (2012) Science , vol.336 , Issue.6077 , pp. 86-90
    • Schulz, C.1    Gomez Perdiguero, E.2
  • 13
    • 30044448462 scopus 로고    scopus 로고
    • Colony-stimulating factor-1 in immunity and inflammation
    • Chitu V, Stanley ER. Colony-stimulating factor-1 in immunity and inflammation. Curr Opin Immunol (2006) 18(1):39-48. doi:10.1016/j.coi.2005.11.006.
    • (2006) Curr Opin Immunol , vol.18 , Issue.1 , pp. 39-48
    • Chitu, V.1    Stanley, E.R.2
  • 14
    • 77957115690 scopus 로고    scopus 로고
    • Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells
    • Wei S, Nandi S, Chitu V, Yeung YG, Yu W, Huang M, et al. Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells. J Leukoc Biol (2010) 88(3):495-505. doi:10.1189/jlb.1209822.
    • (2010) J Leukoc Biol , vol.88 , Issue.3 , pp. 495-505
    • Wei, S.1    Nandi, S.2    Chitu, V.3    Yeung, Y.G.4    Yu, W.5    Huang, M.6
  • 15
    • 84925465211 scopus 로고    scopus 로고
    • Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors
    • Gomez Perdiguero E, Klapproth K, Schulz C, Busch K, Azzoni E, Crozet L, et al. Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors. Nature (2015) 518(7540):547-51. doi:10.1038/nature13989.
    • (2015) Nature , vol.518 , Issue.7540 , pp. 547-551
    • Gomez Perdiguero, E.1    Klapproth, K.2    Schulz, C.3    Busch, K.4    Azzoni, E.5    Crozet, L.6
  • 16
    • 0037963473 scopus 로고    scopus 로고
    • Blood monocytes consist of two principal subsets with distinct migratory properties
    • Geissmann F, Jung S, Littman DR. Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity (2003) 19(1):71-82. doi:10.1016/S1074-7613(03)00174-2.
    • (2003) Immunity , vol.19 , Issue.1 , pp. 71-82
    • Geissmann, F.1    Jung, S.2    Littman, D.R.3
  • 17
    • 34547728312 scopus 로고    scopus 로고
    • Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior
    • Auffray C, Fogg D, Garfa M, Elain G, Join-Lambert O, Kayal S, et al. Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior. Science (2007) 317(5838):666-70. doi:10.1126/science.1142883.
    • (2007) Science , vol.317 , Issue.5838 , pp. 666-670
    • Auffray, C.1    Fogg, D.2    Garfa, M.3    Elain, G.4    Join-Lambert, O.5    Kayal, S.6
  • 18
    • 67649404131 scopus 로고    scopus 로고
    • Blood monocytes: development, heterogeneity, and relationship with dendritic cells
    • Auffray C, Sieweke MH, Geissmann F. Blood monocytes: development, heterogeneity, and relationship with dendritic cells. Annu Rev Immunol (2009) 27:669-92. doi:10.1146/annurev.immunol.021908.132557.
    • (2009) Annu Rev Immunol , vol.27 , pp. 669-692
    • Auffray, C.1    Sieweke, M.H.2    Geissmann, F.3
  • 19
    • 0034659784 scopus 로고    scopus 로고
    • M-1/M-2 macrophages and the Th1/Th2 paradigm
    • Mills CD, Kincaid K, Alt JM, Heilman MJ, Hill AM. M-1/M-2 macrophages and the Th1/Th2 paradigm. J Immunol (2000) 164(12):6166-73. doi:10.4049/jimmunol.164.12.6166.
    • (2000) J Immunol , vol.164 , Issue.12 , pp. 6166-6173
    • Mills, C.D.1    Kincaid, K.2    Alt, J.M.3    Heilman, M.J.4    Hill, A.M.5
  • 20
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser DM, Edwards JP. Exploring the full spectrum of macrophage activation. Nat Rev Immunol (2008) 8(12):958-69. doi:10.1038/nri2448.
    • (2008) Nat Rev Immunol , vol.8 , Issue.12 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 21
    • 77956976681 scopus 로고    scopus 로고
    • Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
    • Biswas SK, Mantovani A. Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat Immunol (2010) 11(10):889-96. doi:10.1038/ni.1937.
    • (2010) Nat Immunol , vol.11 , Issue.10 , pp. 889-896
    • Biswas, S.K.1    Mantovani, A.2
  • 22
    • 7644231561 scopus 로고    scopus 로고
    • The chemokine system in diverse forms of macrophage activation and polarization
    • Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, Locati M. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol (2004) 25(12):677-86. doi:10.1016/j.it.2004.09.015.
    • (2004) Trends Immunol , vol.25 , Issue.12 , pp. 677-686
    • Mantovani, A.1    Sica, A.2    Sozzani, S.3    Allavena, P.4    Vecchi, A.5    Locati, M.6
  • 23
    • 33750813483 scopus 로고    scopus 로고
    • Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression
    • Martinez FO, Gordon S, Locati M, Mantovani A. Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J Immunol (2006) 177(10):7303-11. doi:10.4049/jimmunol.177.10.7303.
    • (2006) J Immunol , vol.177 , Issue.10 , pp. 7303-7311
    • Martinez, F.O.1    Gordon, S.2    Locati, M.3    Mantovani, A.4
  • 24
    • 33745840137 scopus 로고    scopus 로고
    • The IL-21 receptor augments Th2 effector function and alternative macrophage activation
    • Pesce J, Kaviratne M, Ramalingam TR, Thompson RW, Urban JF Jr, Cheever AW, et al. The IL-21 receptor augments Th2 effector function and alternative macrophage activation. J Clin Invest (2006) 116(7):2044-55. doi:10.1172/JCI27727.
    • (2006) J Clin Invest , vol.116 , Issue.7 , pp. 2044-2055
    • Pesce, J.1    Kaviratne, M.2    Ramalingam, T.R.3    Thompson, R.W.4    Urban, J.F.5    Cheever, A.W.6
  • 25
    • 75549085516 scopus 로고    scopus 로고
    • IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation
    • Kurowska-Stolarska M, Stolarski B, Kewin P, Murphy G, Corrigan CJ, Ying S, et al. IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation. J Immunol (2009) 183(10):6469-77. doi:10.4049/jimmunol.0901575.
    • (2009) J Immunol , vol.183 , Issue.10 , pp. 6469-6477
    • Kurowska-Stolarska, M.1    Stolarski, B.2    Kewin, P.3    Murphy, G.4    Corrigan, C.J.5    Ying, S.6
  • 26
    • 38549159026 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of fibrosis
    • Wynn TA. Cellular and molecular mechanisms of fibrosis. J Pathol (2008) 214(2):199-210. doi:10.1002/path.2277.
    • (2008) J Pathol , vol.214 , Issue.2 , pp. 199-210
    • Wynn, T.A.1
  • 27
  • 28
    • 15244356690 scopus 로고    scopus 로고
    • Mechanisms of disease: mechanisms of hepatic fibrosis and therapeutic implications
    • Friedman SL. Mechanisms of disease: mechanisms of hepatic fibrosis and therapeutic implications. Nat Clin Pract Gastroenterol Hepatol (2004) 1(2):98-105. doi:10.1038/ncpgasthep0055.
    • (2004) Nat Clin Pract Gastroenterol Hepatol , vol.1 , Issue.2 , pp. 98-105
    • Friedman, S.L.1
  • 29
    • 84875583686 scopus 로고    scopus 로고
    • Effects of connective tissue growth factor antisense oligonucleotides on the cultured human keloid fibroblasts in vitro
    • Liu JY, Li SR, Ji SX. [Effects of connective tissue growth factor antisense oligonucleotides on the cultured human keloid fibroblasts in vitro]. Zhonghua Zheng Xing Wai Ke Za Zhi (2004) 20(6):454-6.
    • (2004) Zhonghua Zheng Xing Wai Ke Za Zhi , vol.20 , Issue.6 , pp. 454-456
    • Liu, J.Y.1    Li, S.R.2    Ji, S.X.3
  • 31
    • 0027366398 scopus 로고
    • Activation-dependent contractility of rat hepatic lipocytes in culture and in vivo
    • Rockey DC, Housset CN, Friedman SL. Activation-dependent contractility of rat hepatic lipocytes in culture and in vivo. J Clin Invest (1993) 92(4):1795-804. doi:10.1172/JCI116769.
    • (1993) J Clin Invest , vol.92 , Issue.4 , pp. 1795-1804
    • Rockey, D.C.1    Housset, C.N.2    Friedman, S.L.3
  • 32
    • 84898789996 scopus 로고    scopus 로고
    • Macrophage heterogeneity in liver injury and fibrosis
    • Tacke F, Zimmermann HW. Macrophage heterogeneity in liver injury and fibrosis. J Hepatol (2014) 60(5):1090-6. doi:10.1016/j.jhep.2013.12.025.
    • (2014) J Hepatol , vol.60 , Issue.5 , pp. 1090-1096
    • Tacke, F.1    Zimmermann, H.W.2
  • 33
    • 0035159094 scopus 로고    scopus 로고
    • Alpha-smooth muscle actin expression upregulates fibroblast contractile activity
    • Hinz B, Celetta G, Tomasek JJ, Gabbiani G, Chaponnier C. Alpha-smooth muscle actin expression upregulates fibroblast contractile activity. Mol Biol Cell (2001) 12(9):2730-41. doi:10.1091/mbc.12.9.2730.
    • (2001) Mol Biol Cell , vol.12 , Issue.9 , pp. 2730-2741
    • Hinz, B.1    Celetta, G.2    Tomasek, J.J.3    Gabbiani, G.4    Chaponnier, C.5
  • 34
    • 84863733411 scopus 로고    scopus 로고
    • Cellular orchestrators of renal fibrosis
    • Conway B, Hughes J. Cellular orchestrators of renal fibrosis. QJM (2012) 105(7):611-5. doi:10.1093/qjmed/hcr235.
    • (2012) QJM , vol.105 , Issue.7 , pp. 611-615
    • Conway, B.1    Hughes, J.2
  • 35
    • 84859073207 scopus 로고    scopus 로고
    • Recent developments in myofibroblast biology: paradigms for connective tissue remodeling
    • Hinz B, Phan SH, Thannickal VJ, Prunotto M, Desmoulière A, Varga J, et al. Recent developments in myofibroblast biology: paradigms for connective tissue remodeling. Am J Pathol (2012) 180(4):1340-55. doi:10.1016/j.ajpath.2012.02.004.
    • (2012) Am J Pathol , vol.180 , Issue.4 , pp. 1340-1355
    • Hinz, B.1    Phan, S.H.2    Thannickal, V.J.3    Prunotto, M.4    Desmoulière, A.5    Varga, J.6
  • 36
    • 70449372660 scopus 로고    scopus 로고
    • Identification of markers that distinguish monocyte-derived fibrocytes from monocytes, macrophages, and fibroblasts
    • Pilling D, Fan T, Huang D, Kaul B, Gomer RH. Identification of markers that distinguish monocyte-derived fibrocytes from monocytes, macrophages, and fibroblasts. PLoS One (2009) 4(10):e7475. doi:10.1371/journal.pone.0007475.
    • (2009) PLoS One , vol.4 , Issue.10
    • Pilling, D.1    Fan, T.2    Huang, D.3    Kaul, B.4    Gomer, R.H.5
  • 37
    • 77953544771 scopus 로고    scopus 로고
    • Fibrocytes in health and disease
    • Herzog EL, Bucala R. Fibrocytes in health and disease. Exp Hematol (2010) 38(7):548-56. doi:10.1016/j.exphem.2010.03.004.
    • (2010) Exp Hematol , vol.38 , Issue.7 , pp. 548-556
    • Herzog, E.L.1    Bucala, R.2
  • 38
    • 33646858310 scopus 로고    scopus 로고
    • TGFbeta1 induces epithelial-mesenchymal transition, but not myofibroblast transdifferentiation of human kidney tubular epithelial cells in primary culture
    • Forino M, Torregrossa R, Ceol M. TGFbeta1 induces epithelial-mesenchymal transition, but not myofibroblast transdifferentiation of human kidney tubular epithelial cells in primary culture. Int J Exp Pathol (2006) 87(3):197-208. doi:10.1111/j.1365-2613.2006.00479.x.
    • (2006) Int J Exp Pathol , vol.87 , Issue.3 , pp. 197-208
    • Forino, M.1    Torregrossa, R.2    Ceol, M.3
  • 39
    • 77955071008 scopus 로고    scopus 로고
    • Review: endothelial-myofibroblast transition, a new player in diabetic renal fibrosis
    • Li J, Bertram JF. Review: endothelial-myofibroblast transition, a new player in diabetic renal fibrosis. Nephrology (Carlton) (2010) 15(5):507-12. doi:10.1111/j.1440-1797.2010.01363.x.
    • (2010) Nephrology (Carlton) , vol.15 , Issue.5 , pp. 507-512
    • Li, J.1    Bertram, J.F.2
  • 40
    • 0034782524 scopus 로고    scopus 로고
    • Idiopathic membranous glomerulonephritis is associated with altered patterns of self-reactive IgM and IgG antibody repertoires
    • Stahl D, Venetz JP, Lacroix-Desmazes S, Rondeau E, Bonnin E, Kazatchkine MD, et al. Idiopathic membranous glomerulonephritis is associated with altered patterns of self-reactive IgM and IgG antibody repertoires. Scand J Immunol (2001) 54(5):534-42. doi:10.1046/j.1365-3083.2001.01000.x.
    • (2001) Scand J Immunol , vol.54 , Issue.5 , pp. 534-542
    • Stahl, D.1    Venetz, J.P.2    Lacroix-Desmazes, S.3    Rondeau, E.4    Bonnin, E.5    Kazatchkine, M.D.6
  • 41
    • 0038282317 scopus 로고    scopus 로고
    • TGF beta 1 and ET-1 expression in the peripheral blood of patients with cirrhosis
    • Yang L, Liu X, Fu H, Qiang O, Huang M. [TGF beta 1 and ET-1 expression in the peripheral blood of patients with cirrhosis]. Hua Xi Yi Ke Da Xue Xue Bao (2001) 32(2):202-3.
    • (2001) Hua Xi Yi Ke Da Xue Xue Bao , vol.32 , Issue.2 , pp. 202-203
    • Yang, L.1    Liu, X.2    Fu, H.3    Qiang, O.4    Huang, M.5
  • 42
    • 0242582117 scopus 로고    scopus 로고
    • Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models
    • Zeisberg M, Bottiglio C, Kumar N, Maeshima Y, Strutz F, Müller GA, et al. Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models. Am J Physiol Renal Physiol (2003) 285(6):F1060-7. doi:10.1152/ajprenal.00191.2002.
    • (2003) Am J Physiol Renal Physiol , vol.285 , Issue.6 , pp. F1060-F1067
    • Zeisberg, M.1    Bottiglio, C.2    Kumar, N.3    Maeshima, Y.4    Strutz, F.5    Müller, G.A.6
  • 43
    • 34447645515 scopus 로고    scopus 로고
    • Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r-EGFP transgene reporter
    • Rae F, Woods K, Sasmono T, Campanale N, Taylor D, Ovchinnikov DA, et al. Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r-EGFP transgene reporter. Dev Biol (2007) 308(1):232-46. doi:10.1016/j.ydbio.2007.05.027.
    • (2007) Dev Biol , vol.308 , Issue.1 , pp. 232-246
    • Rae, F.1    Woods, K.2    Sasmono, T.3    Campanale, N.4    Taylor, D.5    Ovchinnikov, D.A.6
  • 44
    • 33645525811 scopus 로고    scopus 로고
    • The relationship between albuminuria, MCP-1/CCL2, and interstitial macrophages in chronic kidney disease
    • Eardley KS, Zehnder D, Quinkler M, Lepenies J, Bates RL, Savage CO, et al. The relationship between albuminuria, MCP-1/CCL2, and interstitial macrophages in chronic kidney disease. Kidney Int (2006) 69(7):1189-97. doi:10.1038/sj.ki.5000212.
    • (2006) Kidney Int , vol.69 , Issue.7 , pp. 1189-1197
    • Eardley, K.S.1    Zehnder, D.2    Quinkler, M.3    Lepenies, J.4    Bates, R.L.5    Savage, C.O.6
  • 45
    • 0025123898 scopus 로고
    • Radiologic findings of clonorchiasis
    • Lim JH. Radiologic findings of clonorchiasis. AJR Am J Roentgenol (1990) 155(5):1001-8. doi:10.2214/ajr.155.5.2120938.
    • (1990) AJR Am J Roentgenol , vol.155 , Issue.5 , pp. 1001-1008
    • Lim, J.H.1
  • 46
    • 73349086549 scopus 로고    scopus 로고
    • Effects of liposome clodronate on renal leukocyte populations and renal fibrosis in murine obstructive nephropathy
    • Kitamoto K, Machida Y, Uchida J, Izumi Y, Shiota M, Nakao T, et al. Effects of liposome clodronate on renal leukocyte populations and renal fibrosis in murine obstructive nephropathy. J Pharmacol Sci (2009) 111(3):285-92. doi:10.1254/jphs.09227FP.
    • (2009) J Pharmacol Sci , vol.111 , Issue.3 , pp. 285-292
    • Kitamoto, K.1    Machida, Y.2    Uchida, J.3    Izumi, Y.4    Shiota, M.5    Nakao, T.6
  • 47
    • 0036950667 scopus 로고    scopus 로고
    • Absence of angiotensin II type 1 receptor in bone marrow-derived cells is detrimental in the evolution of renal fibrosis
    • Nishida M, Fujinaka H, Matsusaka T, Price J, Kon V, Fogo AB, et al. Absence of angiotensin II type 1 receptor in bone marrow-derived cells is detrimental in the evolution of renal fibrosis. J Clin Invest (2002) 110(12):1859-68. doi:10.1172/JCI200215045.
    • (2002) J Clin Invest , vol.110 , Issue.12 , pp. 1859-1868
    • Nishida, M.1    Fujinaka, H.2    Matsusaka, T.3    Price, J.4    Kon, V.5    Fogo, A.B.6
  • 48
    • 80053445847 scopus 로고    scopus 로고
    • Inflammation and wound healing: the role of the macrophage
    • Koh TJ, DiPietro LA. Inflammation and wound healing: the role of the macrophage. Expert Rev Mol Med (2011) 13:e23. doi:10.1017/S1462399411001943.
    • (2011) Expert Rev Mol Med , vol.13
    • Koh, T.J.1    DiPietro, L.A.2
  • 50
    • 84877064608 scopus 로고    scopus 로고
    • Macrophages and fibrosis: how resident and infiltrating mononuclear phagocytes orchestrate all phases of tissue injury and repair
    • Lech M, Anders HJ. Macrophages and fibrosis: how resident and infiltrating mononuclear phagocytes orchestrate all phases of tissue injury and repair. Biochim Biophys Acta (2013) 1832(7):989-97. doi:10.1016/j.bbadis.2012.12.001.
    • (2013) Biochim Biophys Acta , vol.1832 , Issue.7 , pp. 989-997
    • Lech, M.1    Anders, H.J.2
  • 51
    • 0038582623 scopus 로고    scopus 로고
    • Gelatinase A (MMP-2) is necessary and sufficient for renal tubular cell epithelial-mesenchymal transformation
    • Cheng S, Lovett DH. Gelatinase A (MMP-2) is necessary and sufficient for renal tubular cell epithelial-mesenchymal transformation. Am J Pathol (2003) 162(6):1937-49. doi:10.1016/S0002-9440(10)64327-1.
    • (2003) Am J Pathol , vol.162 , Issue.6 , pp. 1937-1949
    • Cheng, S.1    Lovett, D.H.2
  • 52
    • 84875693894 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 of tubular and macrophage origin contributes to the pathogenesis of renal fibrosis via macrophage recruitment through osteopontin cleavage
    • Tan TK, Zheng G, Hsu TT, Lee SR, Zhang J, Zhao Y, et al. Matrix metalloproteinase-9 of tubular and macrophage origin contributes to the pathogenesis of renal fibrosis via macrophage recruitment through osteopontin cleavage. Lab Invest (2013) 93(4):434-49. doi:10.1038/labinvest.2013.121.
    • (2013) Lab Invest , vol.93 , Issue.4 , pp. 434-449
    • Tan, T.K.1    Zheng, G.2    Hsu, T.T.3    Lee, S.R.4    Zhang, J.5    Zhao, Y.6
  • 53
    • 16244399175 scopus 로고    scopus 로고
    • Inhibition of matrix metalloproteinases during chronic allograft nephropathy in rats
    • Lutz J, Yao Y, Song E, Antus B, Hamar P, Liu S, et al. Inhibition of matrix metalloproteinases during chronic allograft nephropathy in rats. Transplantation (2005) 79(6):655-61. doi:10.1097/01.TP.0000151644.85832.B5.
    • (2005) Transplantation , vol.79 , Issue.6 , pp. 655-661
    • Lutz, J.1    Yao, Y.2    Song, E.3    Antus, B.4    Hamar, P.5    Liu, S.6
  • 54
    • 34247149014 scopus 로고    scopus 로고
    • Scar-associated macrophages are a major source of hepatic matrix metalloproteinase-13 and facilitate the resolution of murine hepatic fibrosis
    • Fallowfield JA, Mizuno M, Kendall TJ, Constandinou CM, Benyon RC, Duffield JS, et al. Scar-associated macrophages are a major source of hepatic matrix metalloproteinase-13 and facilitate the resolution of murine hepatic fibrosis. J Immunol (2007) 178(8):5288-95. doi:10.4049/jimmunol.178.8.5288.
    • (2007) J Immunol , vol.178 , Issue.8 , pp. 5288-5295
    • Fallowfield, J.A.1    Mizuno, M.2    Kendall, T.J.3    Constandinou, C.M.4    Benyon, R.C.5    Duffield, J.S.6
  • 55
    • 84861576741 scopus 로고    scopus 로고
    • Elastin accumulation is regulated at the level of degradation by macrophage metalloelastase (MMP-12) during experimental liver fibrosis
    • Pellicoro A, Aucott RL, Ramachandran P, Robson AJ, Fallowfield JA, Snowdon VK, et al. Elastin accumulation is regulated at the level of degradation by macrophage metalloelastase (MMP-12) during experimental liver fibrosis. Hepatology (2012) 55(6):1965-75. doi:10.1002/hep.25567.
    • (2012) Hepatology , vol.55 , Issue.6 , pp. 1965-1975
    • Pellicoro, A.1    Aucott, R.L.2    Ramachandran, P.3    Robson, A.J.4    Fallowfield, J.A.5    Snowdon, V.K.6
  • 56
    • 84869208905 scopus 로고    scopus 로고
    • Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis
    • Ramachandran P, Pellicoro A, Vernon MA, Boulter L, Aucott RL, Ali A, et al. Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis. Proc Natl Acad Sci U S A (2012) 109(46):E3186-95. doi:10.1073/pnas.1119964109.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.46 , pp. E3186-E3195
    • Ramachandran, P.1    Pellicoro, A.2    Vernon, M.A.3    Boulter, L.4    Aucott, R.L.5    Ali, A.6
  • 57
    • 84884984479 scopus 로고    scopus 로고
    • Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice
    • Pradere JP, Kluwe J, De Minicis S, Jiao JJ, Gwak GY, Dapito DH, et al. Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice. Hepatology (2013) 58(4):1461-73. doi:10.1002/hep.26429.
    • (2013) Hepatology , vol.58 , Issue.4 , pp. 1461-1473
    • Pradere, J.P.1    Kluwe, J.2    De Minicis, S.3    Jiao, J.J.4    Gwak, G.Y.5    Dapito, D.H.6
  • 58
    • 55849103960 scopus 로고    scopus 로고
    • Macrophage diversity in renal injury and repair
    • Ricardo SD, van Goor H, Eddy AA. Macrophage diversity in renal injury and repair. J Clin Invest (2008) 118(11):3522-30. doi:10.1172/JCI36150.
    • (2008) J Clin Invest , vol.118 , Issue.11 , pp. 3522-3530
    • Ricardo, S.D.1    van Goor, H.2    Eddy, A.A.3
  • 59
    • 0032519925 scopus 로고    scopus 로고
    • Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF
    • Fadok VA, Bratton DL, Konowal A, Freed PW, Westcott JY, Henson PM. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J Clin Invest (1998) 101(4):890-8. doi:10.1172/JCI1112.
    • (1998) J Clin Invest , vol.101 , Issue.4 , pp. 890-898
    • Fadok, V.A.1    Bratton, D.L.2    Konowal, A.3    Freed, P.W.4    Westcott, J.Y.5    Henson, P.M.6
  • 60
    • 77953895145 scopus 로고    scopus 로고
    • Macrophages and renal fibrosis
    • Vernon MA, Mylonas KJ, Hughes J. Macrophages and renal fibrosis. Semin Nephrol (2010) 30(3):302-17. doi:10.1016/j.semnephrol.2010.03.004.
    • (2010) Semin Nephrol , vol.30 , Issue.3 , pp. 302-317
    • Vernon, M.A.1    Mylonas, K.J.2    Hughes, J.3
  • 61
    • 0025395378 scopus 로고
    • The dental health of institutionalized elderly patients: from awareness to action
    • Boisvert R, Boisclair G, Picotte L. [The dental health of institutionalized elderly patients: from awareness to action]. J Can Dent Assoc (1990) 56(3):223-4.
    • (1990) J Can Dent Assoc , vol.56 , Issue.3 , pp. 223-224
    • Boisvert, R.1    Boisclair, G.2    Picotte, L.3
  • 62
    • 20844462878 scopus 로고    scopus 로고
    • Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction
    • Sharma UC, Pokharel S, van Brakel TJ, van Berlo JH, Cleutjens JP, Schroen B, et al. Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction. Circulation (2004) 110(19):3121-8. doi:10.1161/01.CIR.0000147181.65298.4D.
    • (2004) Circulation , vol.110 , Issue.19 , pp. 3121-3128
    • Sharma, U.C.1    Pokharel, S.2    van Brakel, T.J.3    van Berlo, J.H.4    Cleutjens, J.P.5    Schroen, B.6
  • 63
    • 84919492907 scopus 로고    scopus 로고
    • Galectin-3 in patients undergoing ablation of atrial fibrillation
    • Clementy N, Piver E. Galectin-3 in patients undergoing ablation of atrial fibrillation. IJC Metabolic & Endocrine (2014) 5(0):56-60. doi:10.1016/j.ijcme.2014.10.003.
    • (2014) IJC Metabolic & Endocrine , vol.5 , pp. 56-60
    • Clementy, N.1    Piver, E.2
  • 64
    • 84869128422 scopus 로고    scopus 로고
    • MyD88 signaling pathway is involved in renal fibrosis by favoring a TH2 immune response and activating alternative M2 macrophages
    • Braga TT, Correa-Costa M, Guise YF, Castoldi A, de Oliveira CD, Hyane MI, et al. MyD88 signaling pathway is involved in renal fibrosis by favoring a TH2 immune response and activating alternative M2 macrophages. Mol Med (2012) 18:1231-9. doi:10.2119/molmed.2012.00131.
    • (2012) Mol Med , vol.18 , pp. 1231-1239
    • Braga, T.T.1    Correa-Costa, M.2    Guise, Y.F.3    Castoldi, A.4    de Oliveira, C.D.5    Hyane, M.I.6
  • 65
    • 84908499100 scopus 로고    scopus 로고
    • Macrophage heterogeneity, phenotypes, and roles in renal fibrosis
    • Cao Q, Wang Y, Harris DC. Macrophage heterogeneity, phenotypes, and roles in renal fibrosis. Kidney Int Suppl (2011) (2014) 4(1):16-9. doi:10.1038/kisup.2014.4.
    • (2011) Kidney Int Suppl , vol.4 , Issue.1 , pp. 16-19
    • Cao, Q.1    Wang, Y.2    Harris, D.C.3
  • 66
    • 4043055316 scopus 로고    scopus 로고
    • Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis
    • Phillips RJ, Burdick MD, Hong K, Lutz MA, Murray LA, Xue YY, et al. Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis. J Clin Invest (2004) 114(3):438-46. doi:10.1172/JCI200420997.
    • (2004) J Clin Invest , vol.114 , Issue.3 , pp. 438-446
    • Phillips, R.J.1    Burdick, M.D.2    Hong, K.3    Lutz, M.A.4    Murray, L.A.5    Xue, Y.Y.6
  • 67
    • 84908544895 scopus 로고    scopus 로고
    • Macrophages promote renal fibrosis through direct and indirect mechanisms
    • Nikolic-Paterson DJ, Wang S, Lan HY. Macrophages promote renal fibrosis through direct and indirect mechanisms. Kidney Int Suppl (2011) (2014) 4(1):34-8. doi:10.1038/kisup.2014.7.
    • (2011) Kidney Int Suppl , vol.4 , Issue.1 , pp. 34-38
    • Nikolic-Paterson, D.J.1    Wang, S.2    Lan, H.Y.3
  • 68
    • 84929575066 scopus 로고    scopus 로고
    • Macrophages in kidney injury, inflammation, and fibrosis
    • Cao Q, Harris DC. Macrophages in kidney injury, inflammation, and fibrosis. Physiology (Bethesda) (2015) 30(3):183-94. doi:10.1152/physiol.00046.2014.
    • (2015) Physiology (Bethesda) , vol.30 , Issue.3 , pp. 183-194
    • Cao, Q.1    Harris, D.C.2
  • 69
    • 84863702343 scopus 로고    scopus 로고
    • Mechanisms of fibrosis: therapeutic translation for fibrotic disease
    • Wynn TA, Ramalingam TR. Mechanisms of fibrosis: therapeutic translation for fibrotic disease. Nat Med (2012) 18(7):1028-40. doi:10.1038/nm.2807.
    • (2012) Nat Med , vol.18 , Issue.7 , pp. 1028-1040
    • Wynn, T.A.1    Ramalingam, T.R.2
  • 70
    • 84907462313 scopus 로고    scopus 로고
    • Aldosterone induced galectin-3 secretion in vitro and in vivo: from cells to humans
    • Lin YH, Chou CH, Wu XM, Chang YY, Hung CS, Chen YH, et al. Aldosterone induced galectin-3 secretion in vitro and in vivo: from cells to humans. PLoS One (2014) 9(9):e95254. doi:10.1371/journal.pone.0085728.
    • (2014) PLoS One , vol.9 , Issue.9
    • Lin, Y.H.1    Chou, C.H.2    Wu, X.M.3    Chang, Y.Y.4    Hung, C.S.5    Chen, Y.H.6
  • 71
    • 84896905991 scopus 로고    scopus 로고
    • Metabolic regulation of immune responses
    • Ganeshan K, Chawla A. Metabolic regulation of immune responses. Annu Rev Immunol (2014) 32:609-34. doi:10.1146/annurev-immunol-032713-120236.
    • (2014) Annu Rev Immunol , vol.32 , pp. 609-634
    • Ganeshan, K.1    Chawla, A.2
  • 72
    • 84924975551 scopus 로고    scopus 로고
    • Mitochondria in the regulation of innate and adaptive immunity
    • Weinberg SE, Sena LA, Chandel NS. Mitochondria in the regulation of innate and adaptive immunity. Immunity (2015) 42(3):406-17. doi:10.1016/j.immuni.2015.02.002.
    • (2015) Immunity , vol.42 , Issue.3 , pp. 406-417
    • Weinberg, S.E.1    Sena, L.A.2    Chandel, N.S.3
  • 73
    • 84921315334 scopus 로고    scopus 로고
    • Cellular metabolism and macrophage functional polarization
    • Zhu L, Zhao Q, Yang T, Ding W, Zhao Y. Cellular metabolism and macrophage functional polarization. Int Rev Immunol (2015) 34(1):82-100. doi:10.3109/08830185.2014.969421.
    • (2015) Int Rev Immunol , vol.34 , Issue.1 , pp. 82-100
    • Zhu, L.1    Zhao, Q.2    Yang, T.3    Ding, W.4    Zhao, Y.5
  • 74
    • 84942982260 scopus 로고    scopus 로고
    • Metabolic reprogramming in macrophages and dendritic cells in innate immunity
    • Kelly B, O'Neill LA. Metabolic reprogramming in macrophages and dendritic cells in innate immunity. Cell Res (2015) 25(7):771-84. doi:10.1038/cr.2015.68.
    • (2015) Cell Res , vol.25 , Issue.7 , pp. 771-784
    • Kelly, B.1    O'Neill, L.A.2
  • 75
    • 84876285741 scopus 로고    scopus 로고
    • Succinate is an inflammatory signal that induces IL-1beta through HIF-1alpha
    • Tannahill GM, Curtis AM, Adamik J, Palsson-McDermott EM, McGettrick AF, Goel G, et al. Succinate is an inflammatory signal that induces IL-1beta through HIF-1alpha. Nature (2013) 496(7444):238-42. doi:10.1038/nature11986.
    • (2013) Nature , vol.496 , Issue.7444 , pp. 238-242
    • Tannahill, G.M.1    Curtis, A.M.2    Adamik, J.3    Palsson-McDermott, E.M.4    McGettrick, A.F.5    Goel, G.6
  • 76
    • 84924935721 scopus 로고    scopus 로고
    • Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization
    • Jha AK, Huang SC, Sergushichev A, Lampropoulou V, Ivanova Y, Loginicheva E, et al. Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization. Immunity (2015) 42(3):419-30. doi:10.1016/j.immuni.2015.02.005.
    • (2015) Immunity , vol.42 , Issue.3 , pp. 419-430
    • Jha, A.K.1    Huang, S.C.2    Sergushichev, A.3    Lampropoulou, V.4    Ivanova, Y.5    Loginicheva, E.6
  • 77
    • 33745428666 scopus 로고    scopus 로고
    • Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation
    • Vats D, Mukundan L, Odegaard JI, Zhang L, Smith KL, Morel CR, et al. Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation. Cell Metab (2006) 4(1):13-24. doi:10.1016/j.cmet.2006.08.006.
    • (2006) Cell Metab , vol.4 , Issue.1 , pp. 13-24
    • Vats, D.1    Mukundan, L.2    Odegaard, J.I.3    Zhang, L.4    Smith, K.L.5    Morel, C.R.6
  • 79
    • 84879438510 scopus 로고    scopus 로고
    • Enhanceosomes as integrators of hypoxia inducible factor (HIF) and other transcription factors in the hypoxic transcriptional response
    • Pawlus MR, Hu CJ. Enhanceosomes as integrators of hypoxia inducible factor (HIF) and other transcription factors in the hypoxic transcriptional response. Cell Signal (2013) 25(9):1895-903. doi:10.1016/j.cellsig.2013.05.018.
    • (2013) Cell Signal , vol.25 , Issue.9 , pp. 1895-1903
    • Pawlus, M.R.1    Hu, C.J.2
  • 80
    • 84875868055 scopus 로고    scopus 로고
    • A mitochondrial bioenergetic etiology of disease
    • Wallace DC. A mitochondrial bioenergetic etiology of disease. J Clin Invest (2013) 123(4):1405-12. doi:10.1172/JCI61398.
    • (2013) J Clin Invest , vol.123 , Issue.4 , pp. 1405-1412
    • Wallace, D.C.1
  • 81
    • 84901382660 scopus 로고    scopus 로고
    • Mitochondrial DNA genetics and the heteroplasmy conundrum in evolution and disease
    • Wallace DC, Chalkia D. Mitochondrial DNA genetics and the heteroplasmy conundrum in evolution and disease. Cold Spring Harb Perspect Biol (2013) 5(11):a021220. doi:10.1101/cshperspect.a021220.
    • (2013) Cold Spring Harb Perspect Biol , vol.5 , Issue.11
    • Wallace, D.C.1    Chalkia, D.2
  • 82
    • 84941242654 scopus 로고    scopus 로고
    • The role of mitochondrial DNA in mediating alveolar epithelial cell apoptosis and pulmonary fibrosis
    • Kim SJ, Cheresh P, Jablonski RP, Williams DB, Kamp DW. The role of mitochondrial DNA in mediating alveolar epithelial cell apoptosis and pulmonary fibrosis. Int J Mol Sci (2015) 16(9):21486-519. doi:10.3390/ijms161023259.
    • (2015) Int J Mol Sci , vol.16 , Issue.9 , pp. 21486-21519
    • Kim, S.J.1    Cheresh, P.2    Jablonski, R.P.3    Williams, D.B.4    Kamp, D.W.5
  • 83
    • 84970924256 scopus 로고    scopus 로고
    • Deletion of Lkb1 in renal tubular epithelial cells leads to CKD by altering metabolism
    • Han SH, Malaga-Dieguez L, Chinga F, Kang HM, Tao J, Reidy K, et al. Deletion of Lkb1 in renal tubular epithelial cells leads to CKD by altering metabolism. J Am Soc Nephrol (2015). doi:10.1681/ASN.2014121181.
    • (2015) J Am Soc Nephrol
    • Han, S.H.1    Malaga-Dieguez, L.2    Chinga, F.3    Kang, H.M.4    Tao, J.5    Reidy, K.6
  • 84
    • 33846056958 scopus 로고    scopus 로고
    • Interference of cyclosporine on glucose metabolism: potential role in chronic transplantation kidney fibrosis
    • Qiu J, Tu Z, Shi Y, Zhang L, Li Q, Wang W, et al. Interference of cyclosporine on glucose metabolism: potential role in chronic transplantation kidney fibrosis. Transplant Proc (2006) 38(7):2065-8. doi:10.1016/j.transproceed.2006.06.047.
    • (2006) Transplant Proc , vol.38 , Issue.7 , pp. 2065-2068
    • Qiu, J.1    Tu, Z.2    Shi, Y.3    Zhang, L.4    Li, Q.5    Wang, W.6
  • 85
    • 84949685184 scopus 로고    scopus 로고
    • Sirtuin 1 signaling and alcoholic fatty liver disease
    • You M, Jogasuria A, Taylor C, Wu J. Sirtuin 1 signaling and alcoholic fatty liver disease. Hepatobiliary Surg Nutr (2015) 4(2):88-100. doi:10.3978/j.issn.2304-3881.2014.12.06.
    • (2015) Hepatobiliary Surg Nutr , vol.4 , Issue.2 , pp. 88-100
    • You, M.1    Jogasuria, A.2    Taylor, C.3    Wu, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.