Rhein inhibits lipopolysaccharide-induced intestinal injury during sepsis by blocking the toll-like receptor 4 nuclear factor-κB pathway

Molecular Medicine Reports

Volumn 12, Issue 3, 2015, Pages 4415-4421

  Zhang, Ke ^a   Jiao, Xian Fa ^a   Li, Jin Xiu ^a   Wang, Xiao Wen ^a  

^a ZHENGZHOU PEOPLE S HOSPITAL   (China)

Author keywords

Colon; Inflammatory response; Rhein; Sepsis; Toll like receptor 4

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; RESATORVID; RHEIN; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; ANTHRAQUINONE DERIVATIVE; ANTIINFLAMMATORY AGENT; TLR4 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLON; COLON INJURY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; INTESTINE INJURY; MALE; MOUSE; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SEPSIS; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; BAGG ALBINO MOUSE; DRUG EFFECTS; GENE EXPRESSION; GENETICS; IMMUNOLOGY; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PRECLINICAL STUDY; PROTEIN PROCESSING;

MUS; RHEUM RHABARBARUM; RHEUM X HYBRIDUM;

ANIMALS; ANTHRAQUINONES; ANTI-INFLAMMATORY AGENTS; COLON; DRUG EVALUATION, PRECLINICAL; GENE EXPRESSION; LIPOPOLYSACCHARIDES; MALE; MICE, INBRED BALB C; NF-KAPPA B; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; SEPSIS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84935505553     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3925     Document Type: Article

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