-
1
-
-
0032508032
-
Molecular identification of a hyperpolarization-activated channel in sea urchin sperm
-
R. Gauss, R. Seifert, and U.B. Kaupp Molecular identification of a hyperpolarization-activated channel in sea urchin sperm Nature 393 1998 583 587
-
(1998)
Nature
, vol.393
, pp. 583-587
-
-
Gauss, R.1
Seifert, R.2
Kaupp, U.B.3
-
2
-
-
0032508040
-
A family of hyperpolarization-activated mammalian cation channels
-
A. Ludwig, and X. Zong M. Biel A family of hyperpolarization-activated mammalian cation channels Nature 393 1998 587 591
-
(1998)
Nature
, vol.393
, pp. 587-591
-
-
Ludwig, A.1
Zong, X.2
Biel, M.3
-
3
-
-
0032577559
-
Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain
-
B. Santoro, and D.T. Liu G.R. Tibbs Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain Cell 93 1998 717 729
-
(1998)
Cell
, vol.93
, pp. 717-729
-
-
Santoro, B.1
Liu, D.T.2
Tibbs, G.R.3
-
4
-
-
0034818628
-
Cellular expression and functional characterization of four hyperpolarization-activated pacemaker channels in cardiac and neuronal tissues
-
S. Moosmang, and J. Stieber A. Ludwig Cellular expression and functional characterization of four hyperpolarization-activated pacemaker channels in cardiac and neuronal tissues Eur. J. Biochem. 268 2001 1646 1652
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 1646-1652
-
-
Moosmang, S.1
Stieber, J.2
Ludwig, A.3
-
5
-
-
0034661733
-
Molecular and functional heterogeneity of hyperpolarization-activated pacemaker channels in the mouse CNS
-
B. Santoro, and S. Chen S.A. Siegelbaum Molecular and functional heterogeneity of hyperpolarization-activated pacemaker channels in the mouse CNS J. Neurosci. 20 2000 5264 5275
-
(2000)
J. Neurosci.
, vol.20
, pp. 5264-5275
-
-
Santoro, B.1
Chen, S.2
Siegelbaum, S.A.3
-
6
-
-
7744241088
-
HCN2 and HCN1 channels govern the regularity of autonomous pacemaking and synaptic resetting in globus pallidus neurons
-
C.S. Chan, and R. Shigemoto D.J. Surmeier HCN2 and HCN1 channels govern the regularity of autonomous pacemaking and synaptic resetting in globus pallidus neurons J. Neurosci. 24 2004 9921 9932
-
(2004)
J. Neurosci.
, vol.24
, pp. 9921-9932
-
-
Chan, C.S.1
Shigemoto, R.2
Surmeier, D.J.3
-
7
-
-
0027525159
-
h) in neurons of the medial nucleus of the trapezoid body: Voltage-clamp analysis and enhancement by norepinephrine and cAMP suggest a modulatory mechanism in the auditory brain stem
-
h) in neurons of the medial nucleus of the trapezoid body: voltage-clamp analysis and enhancement by norepinephrine and cAMP suggest a modulatory mechanism in the auditory brain stem J. Neurophysiol. 70 1993 1420 1432
-
(1993)
J. Neurophysiol.
, vol.70
, pp. 1420-1432
-
-
Banks, M.I.1
Pearce, R.A.2
Smith, P.H.3
-
8
-
-
0035426072
-
Modulation of a presynaptic hyperpolarization-activated cationic current (I(h)) at an excitatory synaptic terminal in the rat auditory brainstem
-
M.F. Cuttle, and Z. Rusznák I.D. Forsythe Modulation of a presynaptic hyperpolarization-activated cationic current (I(h)) at an excitatory synaptic terminal in the rat auditory brainstem J. Physiol. 534 2001 733 744
-
(2001)
J. Physiol.
, vol.534
, pp. 733-744
-
-
Cuttle, M.F.1
Rusznák, Z.2
Forsythe, I.D.3
-
9
-
-
0029863069
-
h) by cyclic nucleotides in guinea-pig primary afferent neurons
-
h) by cyclic nucleotides in guinea-pig primary afferent neurons J. Physiol. 492 1996 97 106
-
(1996)
J. Physiol.
, vol.492
, pp. 97-106
-
-
Ingram, S.L.1
Williams, J.T.2
-
10
-
-
0033787592
-
Excitability increase induced by β-adrenergic receptor-mediated activation of hyperpolarization-activated cation channels in rat cerebellar basket cells
-
F. Saitow, and S. Konishi Excitability increase induced by β-adrenergic receptor-mediated activation of hyperpolarization-activated cation channels in rat cerebellar basket cells J. Neurophysiol. 84 2000 2026 2034
-
(2000)
J. Neurophysiol.
, vol.84
, pp. 2026-2034
-
-
Saitow, F.1
Konishi, S.2
-
11
-
-
1442300292
-
Immunohistochemical localization of Ih channel subunits, HCN1-4, in the rat brain
-
T. Notomi, and R. Shigemoto Immunohistochemical localization of Ih channel subunits, HCN1-4, in the rat brain J. Comp. Neurol. 471 2004 241 276
-
(2004)
J. Comp. Neurol.
, vol.471
, pp. 241-276
-
-
Notomi, T.1
Shigemoto, R.2
-
12
-
-
0018387132
-
How does adrenaline accelerate the heart?
-
H.F. Brown, D. DiFrancesco, and S.J. Noble How does adrenaline accelerate the heart? Nature 280 1979 235 236
-
(1979)
Nature
, vol.280
, pp. 235-236
-
-
Brown, H.F.1
Difrancesco, D.2
Noble, S.J.3
-
13
-
-
0033522501
-
Two pacemaker channels from human heart with profoundly different activation kinetics
-
A. Ludwig, and X. Zong M. Biel Two pacemaker channels from human heart with profoundly different activation kinetics EMBO J. 18 1999 2323 2329
-
(1999)
EMBO J.
, vol.18
, pp. 2323-2329
-
-
Ludwig, A.1
Zong, X.2
Biel, M.3
-
14
-
-
0033911658
-
Pacemaker oscillations in heart and brain: A key role for hyperpolarization-activated cation channels
-
R. Gauss, and R. Seifert Pacemaker oscillations in heart and brain: a key role for hyperpolarization-activated cation channels Chronobiol. Int. 17 2000 453 469
-
(2000)
Chronobiol. Int.
, vol.17
, pp. 453-469
-
-
Gauss, R.1
Seifert, R.2
-
15
-
-
67651030760
-
Hyperpolarization-activated cation channels: From genes to function
-
M. Biel, and C. Wahl-Schott X. Zong Hyperpolarization-activated cation channels: from genes to function Physiol. Rev. 89 2009 847 885
-
(2009)
Physiol. Rev.
, vol.89
, pp. 847-885
-
-
Biel, M.1
Wahl-Schott, C.2
Zong, X.3
-
16
-
-
0023037826
-
Characterization of single pacemaker channels in cardiac sino-atrial node cells
-
D. DiFrancesco Characterization of single pacemaker channels in cardiac sino-atrial node cells Nature 324 1986 470 473
-
(1986)
Nature
, vol.324
, pp. 470-473
-
-
Difrancesco, D.1
-
17
-
-
0032970234
-
The HCN gene family: Molecular basis of the hyperpolarization-activated pacemaker channels
-
B. Santoro, and G.R. Tibbs The HCN gene family: molecular basis of the hyperpolarization-activated pacemaker channels Ann. N. Y. Acad. Sci. 868 1999 741 764
-
(1999)
Ann. N. Y. Acad. Sci.
, vol.868
, pp. 741-764
-
-
Santoro, B.1
Tibbs, G.R.2
-
18
-
-
0033104823
-
Dual allosteric modulation of pacemaker (f) channels by cAMP and voltage in rabbit SA node
-
D. DiFrancesco Dual allosteric modulation of pacemaker (f) channels by cAMP and voltage in rabbit SA node J. Physiol. 515 1999 367 376
-
(1999)
J. Physiol.
, vol.515
, pp. 367-376
-
-
Difrancesco, D.1
-
19
-
-
0034848889
-
Regulation of hyperpolarization-activated HCN channel gating and cAMP modulation due to interactions of COOH terminus and core transmembrane regions
-
J. Wang, S. Chen, and S.A. Siegelbaum Regulation of hyperpolarization-activated HCN channel gating and cAMP modulation due to interactions of COOH terminus and core transmembrane regions J. Gen. Physiol. 118 2001 237 250
-
(2001)
J. Gen. Physiol.
, vol.118
, pp. 237-250
-
-
Wang, J.1
Chen, S.2
Siegelbaum, S.A.3
-
20
-
-
0037168125
-
Activity-dependent regulation of HCN pacemaker channels by cyclic AMP: Signaling through dynamic allosteric coupling
-
J. Wang, and S. Chen S.A. Siegelbaum Activity-dependent regulation of HCN pacemaker channels by cyclic AMP: signaling through dynamic allosteric coupling Neuron 36 2002 451 461
-
(2002)
Neuron
, vol.36
, pp. 451-461
-
-
Wang, J.1
Chen, S.2
Siegelbaum, S.A.3
-
21
-
-
0012457490
-
Hyperpolarization-activated cation currents: From molecules to physiological function
-
R.B. Robinson, and S.A. Siegelbaum Hyperpolarization-activated cation currents: from molecules to physiological function Annu. Rev. Physiol. 65 2003 453 480
-
(2003)
Annu. Rev. Physiol.
, vol.65
, pp. 453-480
-
-
Robinson, R.B.1
Siegelbaum, S.A.2
-
22
-
-
33645313112
-
CNG and HCN channels: Two peas, one pod
-
K.B. Craven, and W.N. Zagotta CNG and HCN channels: two peas, one pod Annu. Rev. Physiol. 68 2006 375 401
-
(2006)
Annu. Rev. Physiol.
, vol.68
, pp. 375-401
-
-
Craven, K.B.1
Zagotta, W.N.2
-
23
-
-
0035047603
-
Molecular diversity of pacemaker ion channels
-
U.B. Kaupp, and R. Seifert Molecular diversity of pacemaker ion channels Annu. Rev. Physiol. 63 2001 235 257
-
(2001)
Annu. Rev. Physiol.
, vol.63
, pp. 235-257
-
-
Kaupp, U.B.1
Seifert, R.2
-
24
-
-
0141831003
-
Structural basis for modulation and agonist specificity of HCN pacemaker channels
-
W.N. Zagotta, and N.B. Olivier E. Gouaux Structural basis for modulation and agonist specificity of HCN pacemaker channels Nature 425 2003 200 205
-
(2003)
Nature
, vol.425
, pp. 200-205
-
-
Zagotta, W.N.1
Olivier, N.B.2
Gouaux, E.3
-
25
-
-
27144548931
-
Functional expression of the human HCN3 channel
-
J. Stieber, and G. Stöckl F. Hofmann Functional expression of the human HCN3 channel J. Biol. Chem. 280 2005 34635 34643
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 34635-34643
-
-
Stieber, J.1
Stöckl, G.2
Hofmann, F.3
-
26
-
-
34347222939
-
Kinetic relationship between the voltage sensor and the activation gate in spHCN channels
-
A. Bruening-Wright, F. Elinder, and H.P. Larsson Kinetic relationship between the voltage sensor and the activation gate in spHCN channels J. Gen. Physiol. 130 2007 71 81
-
(2007)
J. Gen. Physiol.
, vol.130
, pp. 71-81
-
-
Bruening-Wright, A.1
Elinder, F.2
Larsson, H.P.3
-
27
-
-
0347627834
-
Regulation of hyperpolarization-activated HCN channels by cAMP through a gating switch in binding domain symmetry
-
C. Ulens, and S.A. Siegelbaum Regulation of hyperpolarization-activated HCN channels by cAMP through a gating switch in binding domain symmetry Neuron 40 2003 959 970
-
(2003)
Neuron
, vol.40
, pp. 959-970
-
-
Ulens, C.1
Siegelbaum, S.A.2
-
28
-
-
33846647992
-
Voltage sensor movement and cAMP binding allosterically regulate an inherently voltage-independent closed-open transition in HCN channels
-
S. Chen, and J. Wang S.A. Siegelbaum Voltage sensor movement and cAMP binding allosterically regulate an inherently voltage-independent closed-open transition in HCN channels J. Gen. Physiol. 129 2007 175 188
-
(2007)
J. Gen. Physiol.
, vol.129
, pp. 175-188
-
-
Chen, S.1
Wang, J.2
Siegelbaum, S.A.3
-
29
-
-
84856107576
-
How subunits cooperate in cAMP-induced activation of homotetrameric HCN2 channels
-
J. Kusch, and S. Thon K. Benndorf How subunits cooperate in cAMP-induced activation of homotetrameric HCN2 channels Nat. Chem. Biol. 8 2012 162 169
-
(2012)
Nat. Chem. Biol.
, vol.8
, pp. 162-169
-
-
Kusch, J.1
Thon, S.2
Benndorf, K.3
-
31
-
-
78651189765
-
On the nature of allosteric transitions: A plausible model
-
J. Monod, J. Wyman, and J.P. Changeux On the nature of allosteric transitions: a plausible model J. Mol. Biol. 12 1965 88 118
-
(1965)
J. Mol. Biol.
, vol.12
, pp. 88-118
-
-
Monod, J.1
Wyman, J.2
Changeux, J.P.3
-
32
-
-
84868141482
-
Probability fluxes and transition paths in a Markovian model describing complex subunit cooperativity in HCN2 channels
-
K. Benndorf, J. Kusch, and E. Schulz Probability fluxes and transition paths in a Markovian model describing complex subunit cooperativity in HCN2 channels PLOS Comput. Biol. 8 2012 e1002721
-
(2012)
PLOS Comput. Biol.
, vol.8
-
-
Benndorf, K.1
Kusch, J.2
Schulz, E.3
-
33
-
-
33947501708
-
Relating ligand binding to activation gating in CNGA2 channels
-
C. Biskup, and J. Kusch K. Benndorf Relating ligand binding to activation gating in CNGA2 channels Nature 446 2007 440 443
-
(2007)
Nature
, vol.446
, pp. 440-443
-
-
Biskup, C.1
Kusch, J.2
Benndorf, K.3
-
34
-
-
77954483652
-
Interdependence of receptor activation and ligand binding in HCN2 pacemaker channels
-
J. Kusch, and C. Biskup K. Benndorf Interdependence of receptor activation and ligand binding in HCN2 pacemaker channels Neuron 67 2010 75 85
-
(2010)
Neuron
, vol.67
, pp. 75-85
-
-
Kusch, J.1
Biskup, C.2
Benndorf, K.3
-
35
-
-
79953875921
-
State-dependent cAMP binding to functioning HCN channels studied by patch-clamp fluorometry
-
S. Wu, and Z.V. Vysotskaya L. Zhou State-dependent cAMP binding to functioning HCN channels studied by patch-clamp fluorometry Biophys. J. 100 2011 1226 1232
-
(2011)
Biophys. J.
, vol.100
, pp. 1226-1232
-
-
Wu, S.1
Vysotskaya, Z.V.2
Zhou, L.3
-
36
-
-
10044248233
-
Single-channel behavior of heteromeric α1β glycine receptors: An attempt to detect a conformational change before the channel opens
-
V. Burzomato, and M. Beato L.G. Sivilotti Single-channel behavior of heteromeric α1β glycine receptors: an attempt to detect a conformational change before the channel opens J. Neurosci. 24 2004 10924 10940
-
(2004)
J. Neurosci.
, vol.24
, pp. 10924-10940
-
-
Burzomato, V.1
Beato, M.2
Sivilotti, L.G.3
-
37
-
-
49649102025
-
On the nature of partial agonism in the nicotinic receptor superfamily
-
R. Lape, D. Colquhoun, and L.G. Sivilotti On the nature of partial agonism in the nicotinic receptor superfamily Nature 454 2008 722 727
-
(2008)
Nature
, vol.454
, pp. 722-727
-
-
Lape, R.1
Colquhoun, D.2
Sivilotti, L.G.3
-
38
-
-
84885116519
-
Elementary functional properties of single HCN2 channels
-
S. Thon, R. Schmauder, and K. Benndorf Elementary functional properties of single HCN2 channels Biophys. J. 105 2013 1581 1589
-
(2013)
Biophys. J.
, vol.105
, pp. 1581-1589
-
-
Thon, S.1
Schmauder, R.2
Benndorf, K.3
-
39
-
-
0001941068
-
High-speed solution switching using piezo-based micropositioning stages
-
B. Sakmann, E. Neher, Plenum Press New York
-
P. Jonas High-speed solution switching using piezo-based micropositioning stages B. Sakmann, E. Neher, In Single-Channel Recording 1995 Plenum Press New York 231 243
-
(1995)
In Single-Channel Recording
, pp. 231-243
-
-
Jonas, P.1
-
40
-
-
0037389277
-
Patch-clamp fluorometry recording of conformational rearrangements of ion channels
-
J. Zheng, and W.N. Zagotta Patch-clamp fluorometry recording of conformational rearrangements of ion channels Sci. STKE 2003 2003 PL7
-
(2003)
Sci. STKE
, vol.2003
, pp. PL7
-
-
Zheng, J.1
Zagotta, W.N.2
-
41
-
-
34250474110
-
Derivative-free analogues of the Levenberg-Marquardt and Gauss algorithms or nonlinear least squares approximation
-
K.M. Brown, and J.E. Dennis Derivative-free analogues of the Levenberg-Marquardt and Gauss algorithms or nonlinear least squares approximation Numer. Math. 18 1972 289 297
-
(1972)
Numer. Math.
, vol.18
, pp. 289-297
-
-
Brown, K.M.1
Dennis, J.E.2
-
43
-
-
0000410893
-
A Q-Matrix cookbook
-
B. Sakman, E. Neher, Springer New York
-
D. Colquhoun, and A.G. Hawkes A Q-Matrix cookbook B. Sakman, E. Neher, Single Channel Recording 2009 Springer New York 589 633
-
(2009)
Single Channel Recording
, pp. 589-633
-
-
Colquhoun, D.1
Hawkes, A.G.2
-
44
-
-
84868576729
-
Unraveling subunit cooperativity in homotetrameric HCN2 channels
-
K. Benndorf, S. Thon, and E. Schulz Unraveling subunit cooperativity in homotetrameric HCN2 channels Biophys. J. 103 2012 1860 1869
-
(2012)
Biophys. J.
, vol.103
, pp. 1860-1869
-
-
Benndorf, K.1
Thon, S.2
Schulz, E.3
-
45
-
-
84455192507
-
Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels
-
M. Lolicato, and M. Nardini A. Moroni Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels J. Biol. Chem. 286 2011 44811 44820
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 44811-44820
-
-
Lolicato, M.1
Nardini, M.2
Moroni, A.3
-
46
-
-
84903957215
-
Double electron-electron resonance reveals cAMP-induced conformational change in HCN channels
-
M.C. Puljung, and H.A. DeBerg S. Stoll Double electron-electron resonance reveals cAMP-induced conformational change in HCN channels Proc. Natl. Acad. Sci. USA 111 2014 9816 9821
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 9816-9821
-
-
Puljung, M.C.1
Deberg, H.A.2
Stoll, S.3
-
47
-
-
84907681174
-
Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function
-
A. Saponaro, and S.R. Pauleta A. Moroni Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function Proc. Natl. Acad. Sci. USA 111 2014 14577 14582
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 14577-14582
-
-
Saponaro, A.1
Pauleta, S.R.2
Moroni, A.3
-
48
-
-
84905836722
-
A mechanism for the auto-inhibition of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel opening and its relief by cAMP
-
M. Akimoto, and Z. Zhang G. Melacini A mechanism for the auto-inhibition of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel opening and its relief by cAMP J. Biol. Chem. 289 2014 22205 22220
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 22205-22220
-
-
Akimoto, M.1
Zhang, Z.2
Melacini, G.3
-
49
-
-
0032199006
-
Binding, gating, affinity and efficacy: The interpretation of structure-activity relationships for agonists and of the effects of mutating receptors
-
D. Colquhoun Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors Br. J. Pharmacol. 125 1998 924 947
-
(1998)
Br. J. Pharmacol.
, vol.125
, pp. 924-947
-
-
Colquhoun, D.1
-
50
-
-
0013863816
-
Comparison of experimental binding data and theoretical models in proteins containing subunits
-
D.E. Koshland Jr., G. Némethy, and D. Filmer Comparison of experimental binding data and theoretical models in proteins containing subunits Biochemistry 5 1966 365 385
-
(1966)
Biochemistry
, vol.5
, pp. 365-385
-
-
Koshland, D.E.1
Némethy, G.2
Filmer, D.3
-
51
-
-
0034971172
-
Integrated allosteric model of voltage gating of HCN channels
-
C. Altomare, and A. Bucchi D. DiFrancesco Integrated allosteric model of voltage gating of HCN channels J. Gen. Physiol. 117 2001 519 532
-
(2001)
J. Gen. Physiol.
, vol.117
, pp. 519-532
-
-
Altomare, C.1
Bucchi, A.2
Difrancesco, D.3
-
52
-
-
28244432811
-
Activation of olfactory-type cyclic nucleotide-gated channels is highly cooperative
-
V. Nache, and E. Schulz K. Benndorf Activation of olfactory-type cyclic nucleotide-gated channels is highly cooperative J. Physiol. 569 2005 91 102
-
(2005)
J. Physiol.
, vol.569
, pp. 91-102
-
-
Nache, V.1
Schulz, E.2
Benndorf, K.3
-
53
-
-
0028140472
-
Shaker potassium channel gating. III: Evaluation of kinetic models for activation
-
W.N. Zagotta, T. Hoshi, and R.W. Aldrich Shaker potassium channel gating. III: Evaluation of kinetic models for activation J. Gen. Physiol. 103 1994 321 362
-
(1994)
J. Gen. Physiol.
, vol.103
, pp. 321-362
-
-
Zagotta, W.N.1
Hoshi, T.2
Aldrich, R.W.3
-
54
-
-
0026712418
-
Markov modelling of ensemble current relaxations: Bovine adrenal nicotinic receptor currents analysed
-
D.J. Maconochie, and D.E. Knight Markov modelling of ensemble current relaxations: bovine adrenal nicotinic receptor currents analysed J. Physiol. 454 1992 155 182
-
(1992)
J. Physiol.
, vol.454
, pp. 155-182
-
-
Maconochie, D.J.1
Knight, D.E.2
-
55
-
-
79954425389
-
Structural insights into adrenergic receptor function and pharmacology
-
B.K. Kobilka Structural insights into adrenergic receptor function and pharmacology Trends Pharmacol. Sci. 32 2011 213 218
-
(2011)
Trends Pharmacol. Sci.
, vol.32
, pp. 213-218
-
-
Kobilka, B.K.1
-
56
-
-
84865180885
-
Sequential inter- and intrasubunit rearrangements during activation of dimeric metabotropic glutamate receptor 1
-
V. Hlavackova, and U. Zabel M.J. Lohse Sequential inter- and intrasubunit rearrangements during activation of dimeric metabotropic glutamate receptor 1 Sci. Signal. 5 2012 ra59
-
(2012)
Sci. Signal.
, vol.5
, pp. ra59
-
-
Hlavackova, V.1
Zabel, U.2
Lohse, M.J.3
|