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Volumn 65, Issue , 2016, Pages 234-241

The role of the gut-brain axis in alcohol use disorders

Author keywords

Gut microbiome; Gut brain axis; Neuroinflammation; Vagus nerve; Withdrawal

Indexed keywords

ALCOHOL USE DISORDER; ALCOHOL WITHDRAWAL; ALCOHOLISM; AMYGDALOID NUCLEUS; BEHAVIOR CHANGE; BRAIN FUNCTION; DYSBIOSIS; GUT BRAIN AXIS; HUMAN; INTESTINE FLORA; INTRACELLULAR SIGNALING; LIMBIC SYSTEM; NERVOUS SYSTEM INFLAMMATION; NEUROMODULATION; NONHUMAN; REVIEW; SENSORY NERVE; VAGUS NERVE; ANIMAL; BRAIN; DRUG EFFECTS; IMMUNOMODULATION; MICROBIOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

EID: 84949534153     PISSN: 02785846     EISSN: 18784216     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2015.06.013     Document Type: Review
Times cited : (59)

References (89)
  • 1
    • 84882241031 scopus 로고    scopus 로고
    • The intestinal microbiota, a leaky gut, and abnormal immunity in kidney disease
    • Anders H.-J., Andersen K., Stecher B. The intestinal microbiota, a leaky gut, and abnormal immunity in kidney disease. Kidney Int. [Internet] 2013, 83(6):1010-1016. (Available from: http://www.ncbi.nlm.nih.gov/pubmed/23325079).
    • (2013) Kidney Int. [Internet] , vol.83 , Issue.6 , pp. 1010-1016
    • Anders, H.-J.1    Andersen, K.2    Stecher, B.3
  • 3
    • 14644417860 scopus 로고    scopus 로고
    • The corticotropin-releasing factor (CRF)-system and monoaminergic afferents in the central amygdala: investigations in different mouse strains and comparison with the rat
    • Asan E., Yilmazer-Hanke D.M., Eliava M., Hantsch M., Lesch K.P., Schmitt A. The corticotropin-releasing factor (CRF)-system and monoaminergic afferents in the central amygdala: investigations in different mouse strains and comparison with the rat. Neuroscience 2005, 131:953-967.
    • (2005) Neuroscience , vol.131 , pp. 953-967
    • Asan, E.1    Yilmazer-Hanke, D.M.2    Eliava, M.3    Hantsch, M.4    Lesch, K.P.5    Schmitt, A.6
  • 4
    • 0028881076 scopus 로고
    • Permeability of the blood-brain barrier to soluble cytokine receptors
    • Banks W., Plotkin S., Kastin A. Permeability of the blood-brain barrier to soluble cytokine receptors. Neuroimmunomodulation 1995, 2(3):161-165.
    • (1995) Neuroimmunomodulation , vol.2 , Issue.3 , pp. 161-165
    • Banks, W.1    Plotkin, S.2    Kastin, A.3
  • 5
    • 80051535923 scopus 로고    scopus 로고
    • The intestinal microbiota affect central levels of brain-derived neurotropic factor and behavior in mice
    • Bercik P., Denou E., Collins J., Jackson W., Lu J., Jury J., et al. The intestinal microbiota affect central levels of brain-derived neurotropic factor and behavior in mice. Gastroenterology 2011, 141:599-609.
    • (2011) Gastroenterology , vol.141 , pp. 599-609
    • Bercik, P.1    Denou, E.2    Collins, J.3    Jackson, W.4    Lu, J.5    Jury, J.6
  • 6
    • 84884354746 scopus 로고    scopus 로고
    • So depression is an inflammatory disease, but where does the inflammation come from?
    • BMC Med [Internet]
    • Berk M., Williams L.J., Jacka F.N., O'Neil A., Pasco J.a, Moylan S., et al. So depression is an inflammatory disease, but where does the inflammation come from?. BMC Med. 2013, 11(1):200. BMC Med [Internet], (Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3846682&tool=pmcentrez&rendertype=abstract).
    • (2013) BMC Med. , vol.11 , Issue.1 , pp. 200
    • Berk, M.1    Williams, L.J.2    Jacka, F.N.3    O'Neil, A.4    Pasco, J.A.5    Moylan, S.6
  • 7
    • 80052965474 scopus 로고    scopus 로고
    • Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve
    • (Sep)
    • Bravo J.A., Forsythe P., Chew M.V., Escaravage E., Savignac H.M., Dinan T.G., et al. Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve. Proc. Natl. Acad. Sci. U. S. A. 2011, 108(38):16050-16055. (Sep).
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , Issue.38 , pp. 16050-16055
    • Bravo, J.A.1    Forsythe, P.2    Chew, M.V.3    Escaravage, E.4    Savignac, H.M.5    Dinan, T.G.6
  • 9
    • 84872246853 scopus 로고    scopus 로고
    • Metagenomic analyses of alcohol induced pathogenic alterations in the intestinal microbiome and the effect of Lactobacillus rhamnosus GG treatment
    • Bull-Otterson L., Feng W., Kirpich I., Wang Y., Qin X., Liu Y., et al. Metagenomic analyses of alcohol induced pathogenic alterations in the intestinal microbiome and the effect of Lactobacillus rhamnosus GG treatment. PLoS One 2013, 8(1):4-13.
    • (2013) PLoS One , vol.8 , Issue.1 , pp. 4-13
    • Bull-Otterson, L.1    Feng, W.2    Kirpich, I.3    Wang, Y.4    Qin, X.5    Liu, Y.6
  • 10
    • 77954371737 scopus 로고    scopus 로고
    • Expression of cannabinoid CB1 receptors by vagal afferent neurons: kinetics and role in influencing neurochemical phenotype
    • (Jul)
    • Burdyga G., Varro A., Dimaline R., Thompson D.G., Dockray G.J. Expression of cannabinoid CB1 receptors by vagal afferent neurons: kinetics and role in influencing neurochemical phenotype. Am. J. Physiol. Gastrointest. Liver Physiol. 2010, 299(1):G63-G69. (Jul).
    • (2010) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.299 , Issue.1 , pp. G63-G69
    • Burdyga, G.1    Varro, A.2    Dimaline, R.3    Thompson, D.G.4    Dockray, G.J.5
  • 11
    • 84924571755 scopus 로고    scopus 로고
    • Pathogenesis of Hepatic Encephalopathy and Brain Edema in Acute Liver Failure
    • Elsevier Ltd, March
    • Butterworth R.F. Pathogenesis of Hepatic Encephalopathy and Brain Edema in Acute Liver Failure. J Clin Exp Hepatol [Internet] 2015, 5:S96-S103. Elsevier Ltd, (March, Available from: http://linkinghub.elsevier.com/retrieve/pii/S0973688314000103).
    • (2015) J Clin Exp Hepatol [Internet] , vol.5 , pp. S96-S103
    • Butterworth, R.F.1
  • 13
    • 45149095307 scopus 로고    scopus 로고
    • Induction of c-Fos and DeltaFosB immunoreactivity in rat brain by vagal nerve stimulation
    • (Jul [cited 2014 Jul 31]
    • Cunningham J.T., Mifflin S.W., Gould G.G., Frazer A. Induction of c-Fos and DeltaFosB immunoreactivity in rat brain by vagal nerve stimulation. Neuropsychopharmacology [Internet] 2008, 33(8):1884-1895. (Jul [cited 2014 Jul 31], Available from: http://www.ncbi.nlm.nih.gov/pubmed/17957222).
    • (2008) Neuropsychopharmacology [Internet] , vol.33 , Issue.8 , pp. 1884-1895
    • Cunningham, J.T.1    Mifflin, S.W.2    Gould, G.G.3    Frazer, A.4
  • 14
    • 84916594191 scopus 로고    scopus 로고
    • The gut microbiome and diet in psychiatry
    • Dash S., Clarke G., Berk M., Jacka F.N. The gut microbiome and diet in psychiatry. Curr. Opin. Psychiatry [Internet] 2015, 28:1-6. (Available from: http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:landingpage&an=00001504-201501000-00002).
    • (2015) Curr. Opin. Psychiatry [Internet] , vol.28 , pp. 1-6
    • Dash, S.1    Clarke, G.2    Berk, M.3    Jacka, F.N.4
  • 15
    • 68649109810 scopus 로고    scopus 로고
    • The versatility of the vagus
    • (Jul)
    • Dockray G.J. The versatility of the vagus. Physiol. Behav. 2009, 97(5):531-536. (Jul).
    • (2009) Physiol. Behav. , vol.97 , Issue.5 , pp. 531-536
    • Dockray, G.J.1
  • 16
    • 67349205060 scopus 로고    scopus 로고
    • Cholecystokinin and Gut-Brain Signalling
    • Elsevier B.V.
    • Dockray G.J. Cholecystokinin and Gut-Brain Signalling. Regul Pept [Internet] 2009, 155(1-3):6-10. Elsevier B.V., (Available from: http://dx.doi.org/10.1016/j.regpep.2009.03.015).
    • (2009) Regul Pept [Internet] , pp. 6-10
    • Dockray, G.J.1
  • 17
    • 84904300288 scopus 로고    scopus 로고
    • Gastrointestinal hormones and the dialogue between gut and brain
    • July 2013
    • Dockray G.J. Gastrointestinal hormones and the dialogue between gut and brain. J. Physiol. [Internet] 2014, 00:1-15. (July 2013, Available from: http://www.ncbi.nlm.nih.gov/pubmed/24566540).
    • (2014) J. Physiol. [Internet] , pp. 1-15
    • Dockray, G.J.1
  • 18
    • 79251634224 scopus 로고    scopus 로고
    • Plasticity in vagal afferent neurones during feeding and fasting: mechanisms and significance
    • (Mar)
    • Dockray G.J., Burdyga G. Plasticity in vagal afferent neurones during feeding and fasting: mechanisms and significance. Acta Physiol. (Oxf.) 2011, 201(3):313-321. (Mar).
    • (2011) Acta Physiol. (Oxf.) , vol.201 , Issue.3 , pp. 313-321
    • Dockray, G.J.1    Burdyga, G.2
  • 19
    • 75849155537 scopus 로고    scopus 로고
    • A Meta-analysis of Cytokines in Major Depression
    • Elsevier Inc
    • Dowlati Y., Herrmann N., Swardfager W., Liu H., Sham L., Reim E.K., et al. A Meta-analysis of Cytokines in Major Depression. Biol Psychiatry [Internet] 2010, 67(5):446-457. Elsevier Inc, (Available from: http://dx.doi.org/10.1016/j.biopsych.2009.09.033).
    • (2010) Biol Psychiatry [Internet] , pp. 446-457
    • Dowlati, Y.1    Herrmann, N.2    Swardfager, W.3    Liu, H.4    Sham, L.5    Reim, E.K.6
  • 20
    • 84919383705 scopus 로고    scopus 로고
    • Model-based hypothesis of gut microbe populations and gut/brain barrier permeabilities in the development of regressive autism
    • Downs R., Perna J., Vitelli A., Cook D., Dhurjati P. Model-based hypothesis of gut microbe populations and gut/brain barrier permeabilities in the development of regressive autism. Med Hypotheses 2014, 83(6):649-655. 10.1016/j.mehy.2014.09.005.
    • (2014) Med Hypotheses , vol.83 , Issue.6 , pp. 649-655
    • Downs, R.1    Perna, J.2    Vitelli, A.3    Cook, D.4    Dhurjati, P.5
  • 21
    • 84881550079 scopus 로고    scopus 로고
    • Butyricicoccus pullicaecorum in inflammatory bowel disease
    • Eeckhaut V., Machiels K., Perrier C., Romero C., Maes S., Flahou B., et al. Butyricicoccus pullicaecorum in inflammatory bowel disease. Gut [Internet] 2013, 62(12):1745-1752. (Available from: http://www.ncbi.nlm.nih.gov/pubmed/23263527).
    • (2013) Gut [Internet] , vol.62 , Issue.12 , pp. 1745-1752
    • Eeckhaut, V.1    Machiels, K.2    Perrier, C.3    Romero, C.4    Maes, S.5    Flahou, B.6
  • 22
    • 84899699114 scopus 로고    scopus 로고
    • Immune modulation of the brain-gut-microbe axis
    • (April)
    • El Aidy S., Dinan T.G., Cryan J.F. Immune modulation of the brain-gut-microbe axis. Front. Microbiol. 2014, 5:3-6. (April).
    • (2014) Front. Microbiol. , vol.5 , pp. 3-6
    • El Aidy, S.1    Dinan, T.G.2    Cryan, J.F.3
  • 23
    • 84859298347 scopus 로고    scopus 로고
    • Is Unpredictable Chronic Mild Stress (UCMS) a Reliable Model to Study Depression-induced Neuroinflammation?
    • Elsevier B.V.
    • Farooq R.K., Isingrini E., Tanti A., Le Guisquet A.M., Arlicot N., Minier F., et al. Is Unpredictable Chronic Mild Stress (UCMS) a Reliable Model to Study Depression-induced Neuroinflammation?. Behav Brain Res [Internet] 2012, 231(1):130-137. Elsevier B.V., (Available from: http://dx.doi.org/10.1016/j.bbr.2012.03.020).
    • (2012) Behav Brain Res [Internet] , pp. 130-137
    • Farooq, R.K.1    Isingrini, E.2    Tanti, A.3    Le Guisquet, A.M.4    Arlicot, N.5    Minier, F.6
  • 24
  • 25
    • 84877145046 scopus 로고    scopus 로고
    • Gut-Brain Axis: How the Microbiome Influences Anxiety and Depression
    • Elsevier Ltd
    • Foster J.a., McVey Neufeld K.A. Gut-Brain Axis: How the Microbiome Influences Anxiety and Depression. Trends Neurosci [Internet] 2013, 36(5):305-312. Elsevier Ltd, (Available from: http://dx.doi.org/10.1016/j.tins.2013.01.005).
    • (2013) Trends Neurosci [Internet] , pp. 305-312
    • Foster, J.1    McVey Neufeld, K.A.2
  • 26
    • 84906502000 scopus 로고    scopus 로고
    • The Re-organization of Functional Brain Networks in Pharmacoresistant Epileptic Patients Who Respond to VNS
    • Elsevier Ireland Ltd
    • Fraschini M., Demuru M., Puligheddu M., Floridia S., Polizzi L., Maleci A., et al. The Re-organization of Functional Brain Networks in Pharmacoresistant Epileptic Patients Who Respond to VNS. Neurosci Lett [Internet] 2014, 580:153-157. Elsevier Ireland Ltd, (Available from: http://www.sciencedirect.com/science/article/pii/S030439401400651X).
    • (2014) Neurosci Lett [Internet] , vol.580 , pp. 153-157
    • Fraschini, M.1    Demuru, M.2    Puligheddu, M.3    Floridia, S.4    Polizzi, L.5    Maleci, A.6
  • 27
    • 84861329347 scopus 로고    scopus 로고
    • Temporal changes in innate immune signals in a rat model of alcohol withdrawal in emotional and cardiorespiratory homeostatic nuclei
    • (Jan [cited 2014 Jun 3]
    • Freeman K., Brureau A., Vadigepalli R., Staehle M.M., Brureau M.M., Gonye G.E., et al. Temporal changes in innate immune signals in a rat model of alcohol withdrawal in emotional and cardiorespiratory homeostatic nuclei. J. Neuroinflammation [Internet] 2012, 9(1):97. (Jan [cited 2014 Jun 3], Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3411448&tool=pmcentrez&rendertype=abstract).
    • (2012) J. Neuroinflammation [Internet] , vol.9 , Issue.1 , pp. 97
    • Freeman, K.1    Brureau, A.2    Vadigepalli, R.3    Staehle, M.M.4    Brureau, M.M.5    Gonye, G.E.6
  • 28
    • 84872497073 scopus 로고    scopus 로고
    • Coordinated dynamic gene expression changes in the central nucleus of the amygdala during alcohol withdrawal
    • (Jan [cited 2014 Jun 3]
    • Freeman K., Staehle M.M., Vadigepalli R., Gonye G.E., Ogunnaike B.a., Hoek J.B., et al. Coordinated dynamic gene expression changes in the central nucleus of the amygdala during alcohol withdrawal. Alcohol Clin. Exp. Res. [Internet] 2013, 37(Suppl.1):E88-E100. (Jan [cited 2014 Jun 3], Available from: http://www.ncbi.nlm.nih.gov/pubmed/22827539).
    • (2013) Alcohol Clin. Exp. Res. [Internet] , vol.37 , pp. E88-E100
    • Freeman, K.1    Staehle, M.M.2    Vadigepalli, R.3    Gonye, G.E.4    Ogunnaike, B.5    Hoek, J.B.6
  • 29
    • 84919338749 scopus 로고    scopus 로고
    • Vagal Nerve Stimulation Blocks Interleukin 6-dependent Synaptic Hyperexcitability Induced by Lipopolysaccharide-induced Acute Stress in the Rodent Prefrontal Cortex
    • Elsevier Inc
    • Garcia-Oscos F., Peña D., Housini M., Cheng D., Lopez D., Borland M.S., et al. Vagal Nerve Stimulation Blocks Interleukin 6-dependent Synaptic Hyperexcitability Induced by Lipopolysaccharide-induced Acute Stress in the Rodent Prefrontal Cortex. Brain Behav Immun [Internet] 2015, 43:149-158. Elsevier Inc, (Available from: http://linkinghub.elsevier.com/retrieve/pii/S0889159114004127).
    • (2015) Brain Behav Immun [Internet] , vol.43 , pp. 149-158
    • Garcia-Oscos, F.1    Peña, D.2    Housini, M.3    Cheng, D.4    Lopez, D.5    Borland, M.S.6
  • 30
    • 1842579124 scopus 로고    scopus 로고
    • Brain response to cecal infection with Campylobacter jejuni: analysis with Fos immunohistochemistry
    • (May)
    • Gaykema R.P.A., Goehler L.E., Lyte M. Brain response to cecal infection with Campylobacter jejuni: analysis with Fos immunohistochemistry. Brain Behav. Immun. 2004, 18(3):238-245. (May).
    • (2004) Brain Behav. Immun. , vol.18 , Issue.3 , pp. 238-245
    • Gaykema, R.P.A.1    Goehler, L.E.2    Lyte, M.3
  • 31
    • 84861193847 scopus 로고    scopus 로고
    • Corticotropin-releasing factor (CRF) and neuropeptide Y (NPY): effects on inhibitory transmission in central amygdala, and anxiety- & alcohol-related behaviors
    • (Jun)
    • Gilpin N.W. Corticotropin-releasing factor (CRF) and neuropeptide Y (NPY): effects on inhibitory transmission in central amygdala, and anxiety- & alcohol-related behaviors. Alcohol 2012, 46(4):329-337. (Jun).
    • (2012) Alcohol , vol.46 , Issue.4 , pp. 329-337
    • Gilpin, N.W.1
  • 33
    • 20444374493 scopus 로고    scopus 로고
    • Activation in vagal afferents and central autonomic pathways: early responses to intestinal infection with Campylobacter jejuni
    • (Jul)
    • Goehler L.E., Gaykema R.P.A., Opitz N., Reddaway R., Badr N., Lyte M. Activation in vagal afferents and central autonomic pathways: early responses to intestinal infection with Campylobacter jejuni. Brain Behav. Immun. 2005, 19(4):334-344. (Jul).
    • (2005) Brain Behav. Immun. , vol.19 , Issue.4 , pp. 334-344
    • Goehler, L.E.1    Gaykema, R.P.A.2    Opitz, N.3    Reddaway, R.4    Badr, N.5    Lyte, M.6
  • 34
    • 38649118544 scopus 로고    scopus 로고
    • Campylobacter jejuni infection increases anxiety-like behavior in the holeboard: Possible anatomical substrates for viscerosensory modulation of exploratory behavior
    • Goehler L.E., Park S.M., Opitz N., Lyte M., Gaykema R.P.A. Campylobacter jejuni infection increases anxiety-like behavior in the holeboard: Possible anatomical substrates for viscerosensory modulation of exploratory behavior. Brain Behav. Immun. 2008, 22(3):354-366.
    • (2008) Brain Behav. Immun. , vol.22 , Issue.3 , pp. 354-366
    • Goehler, L.E.1    Park, S.M.2    Opitz, N.3    Lyte, M.4    Gaykema, R.P.A.5
  • 35
    • 84906934110 scopus 로고    scopus 로고
    • Neuroimmune Regulation of Microglial Activity Involved in Neuroinflammation and Neurodegenerative Diseases
    • Elsevier B.V.
    • González H., Elgueta D., Montoya A., Pacheco R. Neuroimmune Regulation of Microglial Activity Involved in Neuroinflammation and Neurodegenerative Diseases. J Neuroimmunol [Internet] 2014, 274(1-2):1-13. Elsevier B.V., (Available from: http://dx.doi.org/10.1016/j.jneuroim.2014.07.012).
    • (2014) J Neuroimmunol [Internet] , pp. 1-13
    • González, H.1    Elgueta, D.2    Montoya, A.3    Pacheco, R.4
  • 36
    • 45549084470 scopus 로고    scopus 로고
    • Brain interleukin-1 mediates chronic stress-induced depression in mice via adrenocortical activation and hippocampal neurogenesis suppression
    • Goshen I., Kreisel T., Ben-Menachem-Zidon O., Licht T., Weidenfeld J., Ben-Hur T., et al. Brain interleukin-1 mediates chronic stress-induced depression in mice via adrenocortical activation and hippocampal neurogenesis suppression. Mol. Psychiatry 2008, 13:717-728.
    • (2008) Mol. Psychiatry , vol.13 , pp. 717-728
    • Goshen, I.1    Kreisel, T.2    Ben-Menachem-Zidon, O.3    Licht, T.4    Weidenfeld, J.5    Ben-Hur, T.6
  • 37
    • 84860644097 scopus 로고    scopus 로고
    • Brain-gut-microbe communication in health and disease
    • (2 DEC(December))
    • Grenham S., Clarke G., Cryan J.F., Dinan T.G. Brain-gut-microbe communication in health and disease. Front. Physiol. 2011, 1-15. (2 DEC(December)).
    • (2011) Front. Physiol. , pp. 1-15
    • Grenham, S.1    Clarke, G.2    Cryan, J.F.3    Dinan, T.G.4
  • 39
    • 84870880811 scopus 로고    scopus 로고
    • The intestinal microbiome and the leaky gut as therapeutic targets in alcoholic liver disease
    • (3 OCT(October))
    • Hartmann P., Chen W.C., Schnabl B. The intestinal microbiome and the leaky gut as therapeutic targets in alcoholic liver disease. Front. Physiol. 2012, 1-10. (3 OCT(October)).
    • (2012) Front. Physiol. , pp. 1-10
    • Hartmann, P.1    Chen, W.C.2    Schnabl, B.3
  • 40
    • 84894118144 scopus 로고    scopus 로고
    • Microbiota Modulate Behavioral and Physiological Abnormalities Associated With Neurodevelopmental Disorders
    • Elsevier Inc
    • Hsiao E.Y., McBride S.W., Hsien S., Sharon G., Hyde E.R., McCue T., et al. Microbiota Modulate Behavioral and Physiological Abnormalities Associated With Neurodevelopmental Disorders. Cell [Internet] 2013, 155(7):1451-1463. Elsevier Inc, (Available from: http://dx.doi.org/10.1016/j.cell.2013.11.024).
    • (2013) Cell [Internet] , pp. 1451-1463
    • Hsiao, E.Y.1    McBride, S.W.2    Hsien, S.3    Sharon, G.4    Hyde, E.R.5    McCue, T.6
  • 41
    • 84873279865 scopus 로고    scopus 로고
    • The Role of the Innate Immune System in Psychiatric Disorders
    • Elsevier Inc
    • Jones K.a., Thomsen C. The Role of the Innate Immune System in Psychiatric Disorders. Mol Cell Neurosci [Internet] 2013, 53:52-62. Elsevier Inc, (Available from: http://dx.doi.org/10.1016/j.mcn.2012.10.002).
    • (2013) Mol Cell Neurosci [Internet] , vol.53 , pp. 52-62
    • Jones, K.1    Thomsen, C.2
  • 43
    • 77953243617 scopus 로고    scopus 로고
    • The intestinal barrier and its regulation by neuroimmune factors
    • Keita A.V., Söderholm J.D. The intestinal barrier and its regulation by neuroimmune factors. Neurogastroenterol. Motil. 2010, 22:718-733.
    • (2010) Neurogastroenterol. Motil. , vol.22 , pp. 718-733
    • Keita, A.V.1    Söderholm, J.D.2
  • 44
    • 67649221730 scopus 로고    scopus 로고
    • A potential role for pro-inflammatory cytokines in regulating synaptic plasticity in major depressive disorder
    • Khairova R.a, Machado-Vieira R., Du J., Manji H.K. A potential role for pro-inflammatory cytokines in regulating synaptic plasticity in major depressive disorder. Int. J. Neuropsychopharmacol. 2009, 12:561-578.
    • (2009) Int. J. Neuropsychopharmacol. , vol.12 , pp. 561-578
    • Khairova, R.A.1    Machado-Vieira, R.2    Du, J.3    Manji, H.K.4
  • 45
    • 84901045104 scopus 로고    scopus 로고
    • Gut vagal afferents differentially modulate innate anxiety and learned fear
    • Klarer M., Arnold M., Gunther L., Winter C., Langhans W., Meyer U. Gut vagal afferents differentially modulate innate anxiety and learned fear. J. Neurosci. [Internet] 2014, 34(21):7067-7076. (Available from: http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.0252-14.2014).
    • (2014) J. Neurosci. [Internet] , vol.34 , Issue.21 , pp. 7067-7076
    • Klarer, M.1    Arnold, M.2    Gunther, L.3    Winter, C.4    Langhans, W.5    Meyer, U.6
  • 46
    • 68149110223 scopus 로고    scopus 로고
    • Evidence for IL-1 receptor blockade as a therapeutic strategy for the treatment of depression
    • Koo J.W., Duman R.S. Evidence for IL-1 receptor blockade as a therapeutic strategy for the treatment of depression. Curr. Opin. Investig. Drugs 2009, 10(7):664-671.
    • (2009) Curr. Opin. Investig. Drugs , vol.10 , Issue.7 , pp. 664-671
    • Koo, J.W.1    Duman, R.S.2
  • 47
    • 0033232472 scopus 로고    scopus 로고
    • Corticotropin-releasing factor, norepinephrine, and stress
    • Koob G.F. Corticotropin-releasing factor, norepinephrine, and stress. Biol. Psychiatry 1999, 46:1167-1180.
    • (1999) Biol. Psychiatry , vol.46 , pp. 1167-1180
    • Koob, G.F.1
  • 48
    • 75149143341 scopus 로고    scopus 로고
    • The Role of CRF and CRF-related Peptides in the Dark Side of Addiction
    • Elsevier B.V., (Feb)
    • Koob G.F. The Role of CRF and CRF-related Peptides in the Dark Side of Addiction. Brain Res 2010, 1314:3-14. Elsevier B.V., (Feb).
    • (2010) Brain Res , vol.1314 , pp. 3-14
    • Koob, G.F.1
  • 49
    • 84925631426 scopus 로고    scopus 로고
    • The dark side of emotion: the addiction perspective
    • Koob G.F. The dark side of emotion: the addiction perspective. Eur. J. Pharmacol. 2015, 753:73-87.
    • (2015) Eur. J. Pharmacol. , vol.753 , pp. 73-87
    • Koob, G.F.1
  • 50
    • 70350573103 scopus 로고    scopus 로고
    • Lactobacillus reuteri enhances excitability of colonic AH neurons by inhibiting calcium-dependent potassium channel opening
    • Kunze W.a., Mao Y.K., Wang B., Huizinga J.D., Ma X., Forsythe P., et al. Lactobacillus reuteri enhances excitability of colonic AH neurons by inhibiting calcium-dependent potassium channel opening. J. Cell. Mol. Med. 2009, 13(8):2261-2270.
    • (2009) J. Cell. Mol. Med. , vol.13 , Issue.8 , pp. 2261-2270
    • Kunze, W.1    Mao, Y.K.2    Wang, B.3    Huizinga, J.D.4    Ma, X.5    Forsythe, P.6
  • 52
    • 84912064085 scopus 로고    scopus 로고
    • Gut microbiota in alcoholic liver disease: pathogenetic role and therapeutic perspectives
    • Malaguarnera G. Gut microbiota in alcoholic liver disease: pathogenetic role and therapeutic perspectives. World J. Gastroenterol. [Internet] 2014, 20(44):16639. (Available from: http://www.wjgnet.com/1007-9327/full/v20/i44/16639.htm).
    • (2014) World J. Gastroenterol. [Internet] , vol.20 , Issue.44 , pp. 16639
    • Malaguarnera, G.1
  • 53
    • 84878987031 scopus 로고    scopus 로고
    • Satiation and stress-induced hypophagia: examining the role of hindbrain neurons expressing prolactin-releasing peptide or glucagon-like peptide 1
    • (January)
    • Maniscalco J.W., Kreisler A.D., Rinaman L. Satiation and stress-induced hypophagia: examining the role of hindbrain neurons expressing prolactin-releasing peptide or glucagon-like peptide 1. Front. Neurosci. 2012, 6:1-17. (January).
    • (2012) Front. Neurosci. , vol.6 , pp. 1-17
    • Maniscalco, J.W.1    Kreisler, A.D.2    Rinaman, L.3
  • 54
    • 79960645242 scopus 로고    scopus 로고
    • Gut Feelings: The Emerging Biology of Gut-Brain Communication
    • Nature Publishing Group
    • Mayer E.a Gut Feelings: The Emerging Biology of Gut-Brain Communication. Nat Rev Neurosci [Internet] 2011, 12:453-466. Nature Publishing Group, (August, Available from: http://dx.doi.org/10.1038/nrn3071).
    • (2011) Nat Rev Neurosci [Internet] , vol.12 , pp. 453-466
    • Mayer, E.A.1
  • 55
    • 84865368221 scopus 로고    scopus 로고
    • Effects of anti-inflammatory vagus nerve stimulation on the cerebral microcirculation in endotoxinemic rats
    • Mihaylova S., Killian A., Mayer K., Pullamsetti S.S., Schermuly R., Rosengarten B. Effects of anti-inflammatory vagus nerve stimulation on the cerebral microcirculation in endotoxinemic rats. J. Neuroinflammation [Internet] 2012, 9(1):183. (Available from: http://www.jneuroinflammation.com/content/9/1/183).
    • (2012) J. Neuroinflammation [Internet] , pp. 183
    • Mihaylova, S.1    Killian, A.2    Mayer, K.3    Pullamsetti, S.S.4    Schermuly, R.5    Rosengarten, B.6
  • 56
    • 63449122724 scopus 로고    scopus 로고
    • Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression
    • Biol Psychiatry [Internet]
    • Miller A.H., Maletic V., Raison C.L. Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression. Soc. Biol. Psychiatry 2009, 65(9):732-741. Biol Psychiatry [Internet], (Available from: http://dx.doi.org/10.1016/j.biopsych.2008.11.029).
    • (2009) Soc. Biol. Psychiatry , vol.65 , Issue.9 , pp. 732-741
    • Miller, A.H.1    Maletic, V.2    Raison, C.L.3
  • 57
    • 34547410247 scopus 로고    scopus 로고
    • Consensus paper of the WFSBP Task Force on Biological Markers: biological markers in depression
    • Mössner R., Mikova O., Koutsilieri E., Saoud M., Ehlis A.-C., Müller N., et al. Consensus paper of the WFSBP Task Force on Biological Markers: biological markers in depression. World J. Biol. Psychiatry 2007, 8(3):141-174.
    • (2007) World J. Biol. Psychiatry , vol.8 , Issue.3 , pp. 141-174
    • Mössner, R.1    Mikova, O.2    Koutsilieri, E.3    Saoud, M.4    Ehlis, A.-C.5    Müller, N.6
  • 58
    • 78149407586 scopus 로고    scopus 로고
    • The Role of the Vagus Nerve in Stroke
    • Elsevier B.V.
    • Mravec B. The Role of the Vagus Nerve in Stroke. Auton Neurosci Basic Clin [Internet] 2010, 158(1-2):8-12. Elsevier B.V., (Available from: http://dx.doi.org/10.1016/j.autneu.2010.08.009).
    • (2010) Auton Neurosci Basic Clin [Internet] , pp. 8-12
    • Mravec, B.1
  • 61
    • 84878011292 scopus 로고    scopus 로고
    • Commensal microbiota modulate murine behaviors in a strictly contamination-free environment confirmed by culture-based methods
    • (Jun)
    • Nishino R., Mikami K., Takahashi H., Tomonaga S., Furuse M., Hiramoto T., et al. Commensal microbiota modulate murine behaviors in a strictly contamination-free environment confirmed by culture-based methods. Neurogastroenterol. Motil. 2013, 25(6):521-528. (Jun).
    • (2013) Neurogastroenterol. Motil. , vol.25 , Issue.6 , pp. 521-528
    • Nishino, R.1    Mikami, K.2    Takahashi, H.3    Tomonaga, S.4    Furuse, M.5    Hiramoto, T.6
  • 62
    • 77649338803 scopus 로고    scopus 로고
    • Noradrenaline Reuptake Inhibitors Inhibit Expression of Chemokines IP-10 and RANTES and Cell Adhesion Molecules VCAM-1 and ICAM-1 in the CNS Following a Systemic Inflammatory Challenge
    • Elsevier B.V.
    • O'Sullivan J.B., Ryan K.M., Harkin A., Connor T.J. Noradrenaline Reuptake Inhibitors Inhibit Expression of Chemokines IP-10 and RANTES and Cell Adhesion Molecules VCAM-1 and ICAM-1 in the CNS Following a Systemic Inflammatory Challenge. J Neuroimmunol [Internet] 2010, 220(1-2):34-42. Elsevier B.V., (Available from: http://dx.doi.org/10.1016/j.jneuroim.2009.12.007).
    • (2010) J Neuroimmunol [Internet] , pp. 34-42
    • O'Sullivan, J.B.1    Ryan, K.M.2    Harkin, A.3    Connor, T.J.4
  • 63
    • 84898596693 scopus 로고    scopus 로고
    • Noninvasive Vagus Nerve Stimulation as Treatment for Trigeminal Allodynia
    • International Association for the Study of Pain, (May [cited 2014 Sep 9]
    • Oshinsky M.L., Murphy A.L., Hekierski H., Cooper M., Simon B.J. Noninvasive Vagus Nerve Stimulation as Treatment for Trigeminal Allodynia. Pain [Internet] 2014, 155(5):1037-1042. International Association for the Study of Pain, (May [cited 2014 Sep 9], Available from: http://www.ncbi.nlm.nih.gov/pubmed/24530613).
    • (2014) Pain [Internet] , pp. 1037-1042
    • Oshinsky, M.L.1    Murphy, A.L.2    Hekierski, H.3    Cooper, M.4    Simon, B.J.5
  • 65
    • 84903971410 scopus 로고    scopus 로고
    • Vagal nerve stimulation reverses aberrant dopamine system function in the methylazoxymethanol acetate rodent model of schizophrenia
    • Perez S.M., Carreno F.R., Frazer A., Lodge D.J. Vagal nerve stimulation reverses aberrant dopamine system function in the methylazoxymethanol acetate rodent model of schizophrenia. J. Neurosci. [Internet] 2014, 34(28):9261-9267. (Available from: http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.0588-14.2014).
    • (2014) J. Neurosci. [Internet] , vol.34 , Issue.28 , pp. 9261-9267
    • Perez, S.M.1    Carreno, F.R.2    Frazer, A.3    Lodge, D.J.4
  • 67
    • 0027373683 scopus 로고
    • Catecholamine-CRF synaptic interaction in a septal bed nucleus: afferents of neurons in the bed nucleus of the stria terminalis
    • Phelix C.F., Liposits Z., Paull W.K. Catecholamine-CRF synaptic interaction in a septal bed nucleus: afferents of neurons in the bed nucleus of the stria terminalis. Brain Res. Bull. U. S. 1994, 33(1):109-119.
    • (1994) Brain Res. Bull. U. S. , vol.33 , Issue.1 , pp. 109-119
    • Phelix, C.F.1    Liposits, Z.2    Paull, W.K.3
  • 69
    • 84942367783 scopus 로고    scopus 로고
    • Amygdalar neuronal plasticity and the interactions of alcohol, sex, and stress
    • [Epub ahead of print]
    • Retson T.a., Hoek J.B., Sterling R.C., Van Bockstaele E.J. Amygdalar neuronal plasticity and the interactions of alcohol, sex, and stress. Brain Struct. Funct. 2014, [Epub ahead of print].
    • (2014) Brain Struct. Funct.
    • Retson, T.1    Hoek, J.B.2    Sterling, R.C.3    Van Bockstaele, E.J.4
  • 70
    • 33750016887 scopus 로고    scopus 로고
    • Divergent projections of catecholaminergic neurons in the nucleus of the solitary tract to limbic forebrain and medullary autonomic brain regions
    • Reyes B.a S., Van Bockstaele E.J. Divergent projections of catecholaminergic neurons in the nucleus of the solitary tract to limbic forebrain and medullary autonomic brain regions. Brain Res. 2006, 1117(1):69-79.
    • (2006) Brain Res. , vol.1117 , Issue.1 , pp. 69-79
    • Reyes, B.A.S.1    Van Bockstaele, E.J.2
  • 71
    • 67650333217 scopus 로고    scopus 로고
    • Principles and clinical implications of the brain-gut-enteric microbiota axis
    • Rhee S.H., Pothoulakis C., Mayer E.a Principles and clinical implications of the brain-gut-enteric microbiota axis. Nat. Rev. Gastroenterol. Hepatol. 2009, 6(5):306-314.
    • (2009) Nat. Rev. Gastroenterol. Hepatol. , vol.6 , Issue.5 , pp. 306-314
    • Rhee, S.H.1    Pothoulakis, C.2    Mayer, E.A.3
  • 72
    • 79551566749 scopus 로고    scopus 로고
    • Hindbrain noradrenergic A2 neurons: diverse roles in autonomic, endocrine, cognitive, and behavioral functions
    • Rinaman L. Hindbrain noradrenergic A2 neurons: diverse roles in autonomic, endocrine, cognitive, and behavioral functions. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2011, 300:R222-R235.
    • (2011) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.300 , pp. R222-R235
    • Rinaman, L.1
  • 73
    • 0022501992 scopus 로고
    • The corticotropin-releasing factor (CRF)-system and monoaminergic afferents in the central amygdala: investigations in different mouse strains and comparison with the rat
    • Sakanaka M., Shibasaki T., Lederis K. The corticotropin-releasing factor (CRF)-system and monoaminergic afferents in the central amygdala: investigations in different mouse strains and comparison with the rat. Brain Res. 1986, 382:213-238.
    • (1986) Brain Res. , vol.382 , pp. 213-238
    • Sakanaka, M.1    Shibasaki, T.2    Lederis, K.3
  • 74
    • 84924577956 scopus 로고    scopus 로고
    • Gut microbiota are related to Parkinson's disease and clinical phenotype
    • Scheperjans F., Aho V., Pereira P.a.B., Koskinen K., Paulin L., Pekkonen E., et al. Gut microbiota are related to Parkinson's disease and clinical phenotype. Mov. Disord. [Internet] 2015, 30(3):350-358. (Available from: http://doi.wiley.com/10.1002/mds.26069).
    • (2015) Mov. Disord. [Internet] , vol.30 , Issue.3 , pp. 350-358
    • Scheperjans, F.1    Aho, V.2    Pereira, P.3    Koskinen, K.4    Paulin, L.5    Pekkonen, E.6
  • 75
    • 84904077057 scopus 로고    scopus 로고
    • Autoimmune Diseases, Gastrointestinal Disorders and the Microbiome in Schizophrenia: More Than a Gut Feeling
    • Elsevier B.V.
    • Severance E.G., Yolken R.H., Eaton W.W. Autoimmune Diseases, Gastrointestinal Disorders and the Microbiome in Schizophrenia: More Than a Gut Feeling. Schizophr Res [Internet] 2014, Elsevier B.V., (Available from: http://dx.doi.org/10.1016/j.schres.2014.06.027).
    • (2014) Schizophr Res [Internet]
    • Severance, E.G.1    Yolken, R.H.2    Eaton, W.W.3
  • 79
    • 84878287270 scopus 로고    scopus 로고
    • Consumption of Fermented Milk Product With Probiotic Modulates Brain Activity
    • Elsevier Inc, (1394-401.e4
    • Tillisch K., Labus J., Kilpatrick L., Jiang Z., Stains J., Ebrat B., et al. Consumption of Fermented Milk Product With Probiotic Modulates Brain Activity. Gastroenterology [Internet] 2013, 144(7). Elsevier Inc, (1394-401.e4, Available from: http://dx.doi.org/10.1053/j.gastro.2013.02.043).
    • (2013) Gastroenterology [Internet]
    • Tillisch, K.1    Labus, J.2    Kilpatrick, L.3    Jiang, Z.4    Stains, J.5    Ebrat, B.6
  • 80
    • 84941791528 scopus 로고    scopus 로고
    • The human gut microbiota with reference to autism spectrum disorder: considering the whole as more than a sum of its parts
    • Toh M.C., Allen-vercoe E. The human gut microbiota with reference to autism spectrum disorder: considering the whole as more than a sum of its parts. Microb. Ecol. Health Dis. 2015, 1:1-7.
    • (2015) Microb. Ecol. Health Dis. , vol.1 , pp. 1-7
    • Toh, M.C.1    Allen-vercoe, E.2
  • 81
    • 84926655893 scopus 로고    scopus 로고
    • Migraine associated with gastrointestinal disorders: review of the literature and clinical implications
    • November
    • Van Hemert S., Breedveld A.C., Rovers J.M., Vermeiden J.P., Witteman B.J., Smits M.G., et al. Migraine associated with gastrointestinal disorders: review of the literature and clinical implications. Front. Neurol. [Internet] 2014, 5:1-7. (November, Available from: http://journal.frontiersin.org/journal/10.3389/fneur.2014.00241/abstract).
    • (2014) Front. Neurol. [Internet] , vol.5 , pp. 1-7
    • Van Hemert, S.1    Breedveld, A.C.2    Rovers, J.M.3    Vermeiden, J.P.4    Witteman, B.J.5    Smits, M.G.6
  • 82
    • 84901491273 scopus 로고    scopus 로고
    • Vagus Nerve Stimulation. . .25years Later! What Do We Know About the Effects on Cognition?
    • Elsevier Ltd
    • Vonck K., Raedt R., Naulaerts J., De Vogelaere F., Thiery E., Van Roost D., et al. Vagus Nerve Stimulation. . .25years Later! What Do We Know About the Effects on Cognition?. Neurosci Biobehav Rev [Internet] 2014, 45C:63-71. Elsevier Ltd, (Available from: http://www.ncbi.nlm.nih.gov/pubmed/24858008).
    • (2014) Neurosci Biobehav Rev [Internet] , vol.45C , pp. 63-71
    • Vonck, K.1    Raedt, R.2    Naulaerts, J.3    De Vogelaere, F.4    Thiery, E.5    Van Roost, D.6
  • 84
    • 84873391360 scopus 로고    scopus 로고
    • A Critical Review of the Mechanism of Action for the Selective Serotonin Reuptake Inhibitors: Do These Drugs Possess Anti-inflammatory Properties and How Relevant Is This in the Treatment of Depression?
    • Elsevier Ltd
    • Walker F.R. A Critical Review of the Mechanism of Action for the Selective Serotonin Reuptake Inhibitors: Do These Drugs Possess Anti-inflammatory Properties and How Relevant Is This in the Treatment of Depression?. Neuropharmacology [Internet] 2013, 67:304-317. Elsevier Ltd, (Available from: http://dx.doi.org/10.1016/j.neuropharm.2012.10.002).
    • (2013) Neuropharmacology [Internet] , vol.67 , pp. 304-317
    • Walker, F.R.1
  • 86
    • 84924020997 scopus 로고    scopus 로고
    • An agent-based modeling framework for evaluating hypotheses on risks for developing autism: effects of the gut microbial environment
    • (Jan)
    • Weston B., Fogal B., Cook D., Dhurjati P. An agent-based modeling framework for evaluating hypotheses on risks for developing autism: effects of the gut microbial environment. Med. Hypotheses 2015, 84(4):395-401. (Jan).
    • (2015) Med. Hypotheses , vol.84 , Issue.4 , pp. 395-401
    • Weston, B.1    Fogal, B.2    Cook, D.3    Dhurjati, P.4
  • 88
    • 85019233393 scopus 로고    scopus 로고
    • Distribution of glucagon-like peptide 1-immunopositive neurons in human caudal medulla
    • Zheng H., Cai L., Rinaman L. Distribution of glucagon-like peptide 1-immunopositive neurons in human caudal medulla. Brain Struct. Funct. 2014, 1-7.
    • (2014) Brain Struct. Funct. , pp. 1-7
    • Zheng, H.1    Cai, L.2    Rinaman, L.3
  • 89
    • 84896138011 scopus 로고    scopus 로고
    • Corticotropin releasing factor: a key role in the neurobiology of addiction
    • (Apr)
    • Zorrilla E.P., Logrip M.L., Koob G.F. Corticotropin releasing factor: a key role in the neurobiology of addiction. Front. Neuroendocrinol. 2014, 35(2):234-244. (Apr).
    • (2014) Front. Neuroendocrinol. , vol.35 , Issue.2 , pp. 234-244
    • Zorrilla, E.P.1    Logrip, M.L.2    Koob, G.F.3


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