Cholecystokinin and gut-brain signalling

Regulatory Peptides

Volumn 155, Issue 1-3, 2009, Pages 6-10

  Dockray, Graham J ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Cholecystokinin; Gastric emptying; Ghrelin; Leptin; Nodose ganglion; PYY; Receptors; Satiety; Vagus

Indexed keywords

CANNABINOID 1 RECEPTOR; CHOLECYSTOKININ; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; G PROTEIN COUPLED RECEPTOR; MELANIN CONCENTRATING HORMONE RECEPTOR 1; PEPTIDE YY [3-36];

BRAIN FUNCTION; FOOD INTAKE; GASTROINTESTINAL TRACT; HUMAN; INTESTINE FUNCTION; NEUROTRANSMISSION; NODOSE GANGLION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; REVIEW; SATIETY; SENSORY NERVE; SIGNAL TRANSDUCTION; STOMACH EMPTYING; VAGUS NERVE;

ANIMALS; CHOLECYSTOKININ; GASTRIC EMPTYING; HUMANS; MODELS, BIOLOGICAL; NERVE TISSUE PROTEINS; UPPER GASTROINTESTINAL TRACT; VAGUS NERVE;

PYRONIA TITHONUS;

EID: 67349205060     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.regpep.2009.03.015     Document Type: Review

References (37)

1. Dockray G.J. Gastrointestinal hormones: gastrin, cholecystokinin, somatostatin and ghrelin. In: Johnson L.R. (Ed). Physiology of the gastrointestinal tract (2006), Elsevier Academic Press, Amsterdam 91-120
2. Gomez R., Navarro M., Ferrer B., Trigo J.M., Bilbao A., Del A.I., Cippitelli A., Nava F., Piomelli D., and Rodriguez d.F. A peripheral mechanism for CB1 cannabinoid receptor-dependent modulation of feeding. J Neurosci 22 (2002) 9612-9617
3. Rodriguez d.F., Navarro M., Gomez R., Escuredo L., Nava F., Fu J., Murillo-Rodriguez E., Giuffrida A., LoVerme J., Gaetani S., Kathuria S., Gall C., and Piomelli D. An anorexic lipid mediator regulated by feeding. Nature 414 (2001) 209-212
4. Dockray G.J. Gut endocrine secretions and their relevance to satiety. Curr Opin Pharmacol 4 (2004) 557-560
5. Murphy K.G., and Bloom S.R. Gut hormones and the regulation of energy homeostasis. Nature 444 (2006) 854-859
6. Raybould H.E. Mechanisms of CCK signaling from gut to brain. Curr Opin Pharmacol 7 (2007) 570-574
7. Chaudhri O.B., Salem V., Murphy K.G., and Bloom S.R. Gastrointestinal satiety signals. Annu Rev Physiol 70 (2008) 239-255
8. McLaughlin J., Grazia L.M., Jones M.N., D'Amato M., Dockray G.J., and Thompson D.G. Fatty acid chain length determines cholecystokinin secretion and effect on human gastric motility. Gastroenterology 116 (1999) 46-53
9. McLaughlin J.T., Lomax R.B., Hall L., Dockray G.J., Thompson D.G., and Warhurst G. Fatty acids stimulate cholecystokinin secretion via an acyl chain length-specific, Ca2+-dependent mechanism in the enteroendocrine cell line STC-1. J Physiol 513 (1998) 11-18
10. Lal S., McLaughlin J., Barlow J., D'Amato M., Giacovelli G., Varro A., Dockray G.J., and Thompson D.G. Cholecystokinin pathways modulate sensations induced by gastric distension in man. Am J Physiol Gastrointest Liver Physiol 287 (2004) G72-G79
11. Leslie F.C., Thompson D.G., McLaughlin J.T., Varro A., Dockray G.J., and Mandal B.K. Plasma cholecystokinin concentrations are elevated in acute upper gastrointestinal infections. Q J Med 96 (2003) 870-871
12. McDermott J.R., Leslie F.C., D'Amato M., Thompson D.G., Grencis R.K., and McLaughlin J.T. Immune control of food intake: enteroendocrine cells are regulated by CD4+ T lymphocytes during small intestinal inflammation. Gut 55 (2006) 492-497
13. Li Y., and Owyang C. Endogenous cholecystokinin stimulates pancreatic enzyme secretion via vagal afferent pathway in rats. Gastroenterology 107 (1994) 525-531
14. Forster E.R., Green T., Elliot M., Bremner A., and Dockray G.J. Gastric emptying in rats: role of afferent neurons and cholecystokinin. Am J Physiol 258 (1990) G552-G556
15. Smith G.P., Jerome C., Cushin B.J., Eterno R., and Simansky K.J. Abdominal vagotomy blocks the satiety effect of cholecystokinin in the rat. Science 213 (1981) 1036-1037
16. Moran T.H., Smith G.P., Hostetler A.M., and McHugh P.R. Transport of cholecystokinin (CCK) binding sites in subdiaphragmatic vagal branches. Brain Res 415 (1987) 149-152
17. Dockray G.J. The brain-gut axis. In: Yamada T. (Ed). Textbook of Gastroenterology (2006), Raven Press, New York 77-92
18. Zhang X., Shi T., Holmberg K., Landry M., Huang W., Xiao H., Ju G., and Hokfelt T. Expression and regulation of the neuropeptide Y Y2 receptor in sensory and autonomic ganglia. Proc Natl Acad Sci U S A 94 (1997) 729-734
19. Zhang X., Ji R.R., Arvidsson J., Lundberg J.M., Bartfai T., Bedecs K., and Hokfelt T. Expression of peptides, nitric oxide synthase and NPY receptor in trigeminal and nodose ganglia after nerve lesions. Exp Brain Res 111 (1996) 393-404
20. Broberger C., Holmberg K., Shi T.J., Dockray G., and Hokfelt T. Expression and regulation of cholecystokinin and cholecystokinin receptors in rat nodose and dorsal root ganglia. Brain Res 903 (2001) 128-140
21. Burdyga G., Lal S., Varro A., Dimaline R., Thompson D.G., and Dockray G.J. Expression of cannabinoid CB1 receptors by vagal afferent neurons is inhibited by cholecystokinin. J Neurosci 24 (2004) 2708-2715
22. Burdyga G., Varro A., Dimaline R., Thompson D.G., and Dockray G.J. Feeding-dependent depression of melanin-concentrating hormone and melanin-concentrating hormone receptor-1 expression in vagal afferent neurones. Neuroscience 137 (2006) 1405-1415
23. de Lartigue G., Dimaline R., Varro A., and Dockray G.J. Cocaine- and amphetamine-regulated transcript: stimulation of expression in rat vagal afferent neurons by cholecystokinin and suppression by ghrelin. J Neurosci 27 (2007) 2876-2882
24. Buyse M., Ovesjo M.L., Goiot H., Guilmeau S., Peranzi G., Moizo L., Walker F., Lewin M.J., Meister B., and Bado A. Expression and regulation of leptin receptor proteins in afferent and efferent neurons of the vagus nerve. Eur J Neurosci 14 (2001) 64-72
25. Burdyga G., de Lartigue G., Raybould H.E., Morris R., Dimaline R., Varro A., Thompson D.G., and Dockray G.J. Cholecystokinin regulates expression of Y2 receptors in vagal afferent neurons serving the stomach. J Neurosci 28 (2008) 11583-11592
26. Burdyga G., Varro A., Dimaline R., Thompson D.G., and Dockray G.J. Ghrelin receptors in rat and human nodose ganglia: putative role in regulating CB-1 and MCH receptor abundance. Am J Physiol Gastrointest Liver Physiol 290 (2006) G1289-G1297
27. Blackshaw L.A., and Grundy D. Effects of cholecystokinin (CCK-8) on two classes of gastroduodenal vagal afferent fibre. J Auton Nerv Syst 31 (1990) 191-201
28. Schwartz G.J., McHugh P.R., and Moran T.H. Integration of vagal afferent responses to gastric loads and cholecystokinin in rats. Am J Physiol 261 (1991) R64-R69
29. Peters J.H., Karpiel A.B., Ritter R.C., and Simasko S.M. Cooperative activation of cultured vagal afferent neurons by leptin and cholecystokinin. Endocrinology 145 (2004) 3652-3657
30. Whited K.L., Tso P., and Raybould H.E. Involvement of apolipoprotein A-IV and cholecystokinin1 receptors in exogenous peptide YY3 36-induced stimulation of intestinal feedback. Endocrinology 148 (2007) 4695-4703
31. Schwartz G.J., McHugh P.R., and Moran T.H. Gastric loads and cholecystokinin synergistically stimulate rat gastric vagal afferents. Am J Physiol 265 (1993) R872-R876
32. Gourcerol G., Wang L., Wang Y.H., Million M., and Tache Y. Urocortins and cholecystokinin-8 act synergistically to increase satiation in lean but not obese mice: involvement of corticotropin-releasing factor receptor-2 pathway. Endocrinology 148 (2007) 6115-6123
33. Wang Y.H., Tache Y., Sheibel A.B., Go V.L., and Wei J.Y. Two types of leptin-responsive gastric vagal afferent terminals: an in vitro single-unit study in rats. Am J Physiol 273 (1997) R833-R837
34. Barrachina M.D., Martinez V., Wang L., Wei J.Y., and Tache Y. Synergistic interaction between leptin and cholecystokinin to reduce short-term food intake in lean mice. Proc Natl Acad Sci U S A 94 (1997) 10455-10460
35. Burdyga G., Lal S., Spiller D., Jiang W., Thompson D.G., Attwood S., Saeed S., Grundy D., Varro A., Dimaline R., and Dockray G.J. Localization of orexin-1 receptors to vagal afferent neurons in the rat and humans. Gastroenterology 124 (2003) 129-139
36. Date Y., Toshinai K., Koda S., Miyazato M., Shimbara T., Tsuruta T., Niijima A., Kangawa K., and Nakazato M. Peripheral interaction of ghrelin with cholecystokinin on feeding regulation. Endocrinology 146 (2005) 3518-3525
37. Gourcerol G., Million M., Adelson D.W., Wang Y., Wang L., Rivier J., St-Pierre D.H., and Tache Y. Lack of interaction between peripheral injection of CCK and obestatin in the regulation of gastric satiety signaling in rodents. Peptides 27 (2006) 2811-2819