Macrophage autophagy limits acute toxic liver injury in mice through down regulation of interleukin-1β

Journal of Hepatology

Volumn 64, Issue 1, 2016, Pages 118-127

  Ilyas, Ghulam ^a   Zhao, Enpeng ^a   Liu, Kun ^a   Lin, Yu ^a   Tesfa, Lydia ^b   Tanaka, Kathryn E ^b   Czaja, Mark J ^a  

^a MARION BESSIN LIVER RESEARCH CENTER   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Apoptosis; Galactosamine; Inflammasome; Innate immunity; Kupffer cell; Lipopolysaccharide; Macrophage

Indexed keywords

ALANINE AMINOTRANSFERASE; AUTOPHAGY PROTEIN 5; CASPASE 3; CASPASE 7; CASPASE 8; CYCLOOXYGENASE 2; GALACTOSAMINE; GAMMA INTERFERON; INFLAMMASOME; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 18; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; NITRIC OXIDE SYNTHASE; TUMOR NECROSIS FACTOR; ATG5 PROTEIN, MOUSE; AUTOPHAGY RELATED PROTEIN 5; CYTOKINE; IL1B PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; DOWN REGULATION; ENZYME ACTIVATION; GENE INDUCTION; IMMUNOBLOTTING; IMMUNOFLUORESCENCE TEST; KUPFFER CELL; LEUKOCYTE ACTIVATION; LIVER CELL; LIVER CELL CULTURE; LIVER HISTOLOGY; LIVER TOXICITY; MACROPHAGE; MALE; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUNEL ASSAY; WILD TYPE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CHEMICAL AND DRUG INDUCED LIVER INJURY; PHYSIOLOGY;

ANIMALS; AUTOPHAGY; AUTOPHAGY-RELATED PROTEIN 5; CHEMICAL AND DRUG INDUCED LIVER INJURY; CYTOKINES; DOWN-REGULATION; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICROTUBULE-ASSOCIATED PROTEINS;

EID: 84949516182     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2015.08.019     Document Type: Article

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