-
1
-
-
74049141478
-
Epigenetics in cancer
-
Sharma, S., Kelly, T. K., & Jones, P. A. Epigenetics in cancer. Carcinogenesis 31, 27-36 (2010
-
(2010)
Carcinogenesis
, vol.31
, pp. 27-36
-
-
Sharma, S.1
Kelly, T.K.2
Jones, P.A.3
-
2
-
-
77957970301
-
Epigenetic modifications and human disease
-
Portela, A., & Esteller, M. Epigenetic modifications and human disease. Nat Biotechnol 28, 1057-1068 (2010
-
(2010)
Nat Biotechnol
, vol.28
, pp. 1057-1068
-
-
Portela, A.1
Esteller, M.2
-
3
-
-
0036532202
-
Histone methylation in transcriptional control
-
Kouzarides, T. Histone methylation in transcriptional control. Curr Opin Genet Dev 12, 198-209 (2002
-
(2002)
Curr Opin Genet Dev
, vol.12
, pp. 198-209
-
-
Kouzarides, T.1
-
4
-
-
33845786515
-
The control of histone lysine methylation in epigenetic regulation
-
Volkel, P., & Angrand, P. O. The control of histone lysine methylation in epigenetic regulation. Biochimie 89, 1-20 (2007
-
(2007)
Biochimie
, vol.89
, pp. 1-20
-
-
Volkel, P.1
Angrand, P.O.2
-
5
-
-
0037693853
-
Trimethylated lysine 9 of histone H3 is a mark for DNA methylation in Neurospora crassa
-
Tamaru, H., et al. Trimethylated lysine 9 of histone H3 is a mark for DNA methylation in Neurospora crassa. Nat Genet 34, 75-79 (2003
-
(2003)
Nat Genet
, vol.34
, pp. 75-79
-
-
Tamaru, H.1
-
6
-
-
3042781030
-
Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27
-
Kirmizis, A., et al. Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27. Genes Dev 18, 1592-1605 (2004
-
(2004)
Genes Dev
, vol.18
, pp. 1592-1605
-
-
Kirmizis, A.1
-
7
-
-
2642542643
-
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin
-
Schotta, G., et al. A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. Genes Dev 18, 1251-1262 (2004
-
(2004)
Genes Dev
, vol.18
, pp. 1251-1262
-
-
Schotta, G.1
-
8
-
-
0037979272
-
Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II
-
Krogan, N. J., et al. Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II. Mol Cell Biol 23, 4207-4218 (2003
-
(2003)
Mol Cell Biol
, vol.23
, pp. 4207-4218
-
-
Krogan, N.J.1
-
9
-
-
0037083757
-
Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation
-
Nishioka, K., et al. Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation. Genes Dev 16, 479-489 (2002
-
(2002)
Genes Dev
, vol.16
, pp. 479-489
-
-
Nishioka, K.1
-
10
-
-
0035815360
-
Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly
-
Nakayama, J., Rice, J. C., Strahl, B. D., Allis, C. D., & Grewal, S. I. Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly. Science 292, 110-113 (2001
-
(2001)
Science
, vol.292
, pp. 110-113
-
-
Nakayama, J.1
Rice, J.C.2
Strahl, B.D.3
Allis, C.D.4
Grewal, S.I.5
-
11
-
-
1242271994
-
HP1 is essential for DNA methylation in neurospora
-
Freitag, M., Hickey, P. C., Khlafallah, T. K., Read, N. D., & Selker, E. U. HP1 is essential for DNA methylation in neurospora. Mol Cell 13, 427-434 (2004
-
(2004)
Mol Cell
, vol.13
, pp. 427-434
-
-
Freitag, M.1
Hickey, P.C.2
Khlafallah, T.K.3
Read, N.D.4
Selker, E.U.5
-
12
-
-
0034632829
-
Regulation of chromatin structure by site-specific histone H3 methyltransferases
-
Rea, S., et al. Regulation of chromatin structure by site-specific histone H3 methyltransferases. Nature 406, 593-599 (2000
-
(2000)
Nature
, vol.406
, pp. 593-599
-
-
Rea, S.1
-
13
-
-
0034461595
-
Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression
-
O?Carroll, D., et al. Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression. Mol Cell Biol 20, 9423-9433 (2000
-
(2000)
Mol Cell Biol
, vol.20
, pp. 9423-9433
-
-
O'Carroll, D.1
-
14
-
-
17944380227
-
Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability
-
Peters, A. H., et al. Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability. Cell 107, 323-337 (2001
-
(2001)
Cell
, vol.107
, pp. 323-337
-
-
Peters, A.H.1
-
15
-
-
0037052539
-
A complex with chromatin modifiers that occupies E2F-And Myc-responsive genes in G0 cells
-
Ogawa, H., Ishiguro, K., Gaubatz, S., Livingston, D. M., & Nakatani, Y. A complex with chromatin modifiers that occupies E2F-And Myc-responsive genes in G0 cells. Science 296, 1132-1136 (2002
-
(2002)
Science
, vol.296
, pp. 1132-1136
-
-
Ogawa, H.1
Ishiguro, K.2
Gaubatz, S.3
Livingston, D.M.4
Nakatani, Y.5
-
16
-
-
0035816682
-
Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3
-
Tachibana, M., Sugimoto, K., Fukushima, T., & Shinkai, Y. Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3. J Biol Chem 276, 25309-25317 (2001
-
(2001)
J Biol Chem
, vol.276
, pp. 25309-25317
-
-
Tachibana, M.1
Sugimoto, K.2
Fukushima, T.3
Shinkai, Y.4
-
17
-
-
0037089626
-
SETDB1: A novel KAP-1-Associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins
-
Schultz, D. C., Ayyanathan, K., Negorev, D., Maul, G. G., & Rauscher, F. J., 3rd. SETDB1: a novel KAP-1-Associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins. Genes Dev 16, 919-932 (2002
-
(2002)
Genes Dev
, vol.16
, pp. 919-932
-
-
Schultz, D.C.1
Ayyanathan, K.2
Negorev, D.3
Maul, G.G.4
Rauscher, F.J.5
-
18
-
-
0345275880
-
Inactivation of a histone methyltransferase by mutations in human cancers
-
Kim, K. C., Geng, L., & Huang, S. Inactivation of a histone methyltransferase by mutations in human cancers. Cancer Res 63, 7619-7623 (2003
-
(2003)
Cancer Res
, vol.63
, pp. 7619-7623
-
-
Kim, K.C.1
Geng, L.2
Huang, S.3
-
19
-
-
20144388930
-
Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9
-
Tachibana, M., et al. Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9. Genes Dev 19, 815-826 (2005
-
(2005)
Genes Dev
, vol.19
, pp. 815-826
-
-
Tachibana, M.1
-
20
-
-
33745999467
-
Zinc finger protein Wiz links G9a/GLP histone methyltransferases to the co-repressor molecule CtBP
-
Ueda, J., Tachibana, M., Ikura, T., & Shinkai, Y. Zinc finger protein Wiz links G9a/GLP histone methyltransferases to the co-repressor molecule CtBP. J Biol Chem 281, 20120-20128 (2006
-
(2006)
J Biol Chem
, vol.281
, pp. 20120-20128
-
-
Ueda, J.1
Tachibana, M.2
Ikura, T.3
Shinkai, Y.4
-
21
-
-
54349095323
-
G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription
-
Tachibana, M., Matsumura, Y., Fukuda, M., Kimura, H., & Shinkai, Y. G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription. EMBO J 27, 2681-2690 (2008
-
(2008)
EMBO J
, vol.27
, pp. 2681-2690
-
-
Tachibana, M.1
Matsumura, Y.2
Fukuda, M.3
Kimura, H.4
Shinkai, Y.5
-
22
-
-
0037099413
-
G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis
-
Tachibana, M., et al. G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis. Genes Dev 16, 1779-1791 (2002
-
(2002)
Genes Dev
, vol.16
, pp. 1779-1791
-
-
Tachibana, M.1
-
23
-
-
79955029493
-
Epigenetic reprogramming and development: A unique heterochromatin organization in the preimplantation mouse embryo
-
Burton, A., & Torres-Padilla, M. E. Epigenetic reprogramming and development: a unique heterochromatin organization in the preimplantation mouse embryo. Brief Funct Genomics 9, 444-454 (2010
-
(2010)
Brief Funct Genomics
, vol.9
, pp. 444-454
-
-
Burton, A.1
Torres-Padilla, M.E.2
-
24
-
-
3042756180
-
Regulation of histone H3 lysine 9 methylation in oocytes and early pre-implantation embryos
-
Liu, H., Kim, J. M., & Aoki, F. Regulation of histone H3 lysine 9 methylation in oocytes and early pre-implantation embryos. Development 131, 2269-2280 (2004
-
(2004)
Development
, vol.131
, pp. 2269-2280
-
-
Liu, H.1
Kim, J.M.2
Aoki, F.3
-
25
-
-
23144456323
-
Asymmetry in histone H3 variants and lysine methylation between paternal and maternal chromatin of the early mouse zygote
-
van der Heijden, G. W., et al. Asymmetry in histone H3 variants and lysine methylation between paternal and maternal chromatin of the early mouse zygote. Mech Dev 122, 1008-1022 (2005
-
(2005)
Mech Dev
, vol.122
, pp. 1008-1022
-
-
Van Der Heijden, G.W.1
-
26
-
-
8844282619
-
Differential dynamics of histone H3 methylation at positions K4 and K9 in the mouse zygote
-
Lepikhov, K., & Walter, J. Differential dynamics of histone H3 methylation at positions K4 and K9 in the mouse zygote. BMC Dev Biol 4, 12 (2004
-
(2004)
BMC Dev Biol
, vol.4
, pp. 12
-
-
Lepikhov, K.1
Walter, J.2
-
27
-
-
14844286976
-
Dynamic chromatin modifications characterise the first cell cycle in mouse embryos
-
Santos, F., Peters, A. H., Otte, A. P., Reik, W., & Dean, W. Dynamic chromatin modifications characterise the first cell cycle in mouse embryos. Dev Biol 280, 225-236 (2005
-
(2005)
Dev Biol
, vol.280
, pp. 225-236
-
-
Santos, F.1
Peters, A.H.2
Otte, A.P.3
Reik, W.4
Dean, W.5
-
28
-
-
0022370488
-
Puromycin photoaffinity labels small-And large-subunit proteins at the A site of the Drosophila ribosome
-
Gilly, M., & Pellegrini, M. Puromycin photoaffinity labels small-And large-subunit proteins at the A site of the Drosophila ribosome. Biochemistry 24, 5781-5786 (1985
-
(1985)
Biochemistry
, vol.24
, pp. 5781-5786
-
-
Gilly, M.1
Pellegrini, M.2
-
29
-
-
0037665145
-
Roscovitine and other purines as kinase inhibitors from starfish oocytes to clinical trials
-
Meijer, L., & Raymond, E. Roscovitine and other purines as kinase inhibitors. From starfish oocytes to clinical trials. Acc Chem Res 36, 417-425 (2003
-
(2003)
Acc Chem Res
, vol.36
, pp. 417-425
-
-
Meijer, L.1
Raymond, E.2
-
30
-
-
0037392942
-
The specificities of protein kinase inhibitors: An update
-
Bain, J., McLauchlan, H., Elliott, M., & Cohen, P. The specificities of protein kinase inhibitors: an update. Biochem J 371, 199-204 (2003
-
(2003)
Biochem J
, vol.371
, pp. 199-204
-
-
Bain, J.1
McLauchlan, H.2
Elliott, M.3
Cohen, P.4
-
31
-
-
0018948573
-
Mechanism of inhibition of herpes simplex virus and vaccinia virus DNA polymerases by aphidicolin, a highly specific inhibitor of DNA replication in eucaryotes
-
Pedrali-Noy, G., & Spadari, S. Mechanism of inhibition of herpes simplex virus and vaccinia virus DNA polymerases by aphidicolin, a highly specific inhibitor of DNA replication in eucaryotes. J Virol 36, 457-464 (1980
-
(1980)
J Virol
, vol.36
, pp. 457-464
-
-
Pedrali-Noy, G.1
Spadari, S.2
-
32
-
-
62049083789
-
Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294
-
Chang, Y., et al. Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294. Nat Struct Mol Biol 16, 312-317 (2009
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 312-317
-
-
Chang, Y.1
-
33
-
-
33846783261
-
Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase
-
Kubicek, S., et al. Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase. Mol Cell 25, 473-481 (2007
-
(2007)
Mol Cell
, vol.25
, pp. 473-481
-
-
Kubicek, S.1
-
34
-
-
79955460159
-
H3K9 methyltransferase G9a and the related molecule GLP
-
Shinkai, Y., & Tachibana, M. H3K9 methyltransferase G9a and the related molecule GLP. Genes Dev 25, 781-788 (2011
-
(2011)
Genes Dev
, vol.25
, pp. 781-788
-
-
Shinkai, Y.1
Tachibana, M.2
-
35
-
-
84925003240
-
The zinc finger proteins ZNF644 and WIZ regulate the G9a/GLP complex for gene repression
-
Bian, C., Chen, Q., & Yu, X. The zinc finger proteins ZNF644 and WIZ regulate the G9a/GLP complex for gene repression. Elife 4 (2015
-
(2015)
Elife
, vol.4
-
-
Bian, C.1
Chen, Q.2
Yu, X.3
-
36
-
-
77249087063
-
Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin
-
Schneider-Poetsch, T., et al. Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin. Nat Chem Biol 6, 209-217 (2010
-
(2010)
Nat Chem Biol
, vol.6
, pp. 209-217
-
-
Schneider-Poetsch, T.1
-
37
-
-
84862908426
-
Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin
-
Liu, J., Xu, Y., Stoleru, D., & Salic, A. Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin. Proc Natl Acad Sci USA 109, 413-418 (2012
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 413-418
-
-
Liu, J.1
Xu, Y.2
Stoleru, D.3
Salic, A.4
-
38
-
-
77950858804
-
Epigenetic chromatin modifications in the cortical spreading depression
-
Passaro, D., et al. Epigenetic chromatin modifications in the cortical spreading depression. Brain Res 1329, 1-9 (2010
-
(2010)
Brain Res
, vol.1329
, pp. 1-9
-
-
Passaro, D.1
-
39
-
-
84872037574
-
PGC7 H3K9me2 and Tet3: Regulators of DNA methylation in zygotes
-
Kang, J., Kalantry, S., & Rao, A. PGC7, H3K9me2 and Tet3: regulators of DNA methylation in zygotes. Cell Res 23, 6-9 (2013
-
(2013)
Cell Res
, vol.23
, pp. 6-9
-
-
Kang, J.1
Kalantry, S.2
Rao, A.3
-
40
-
-
84862551364
-
PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos
-
Nakamura, T., et al. PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos. Nature 486, 415-419 (2012
-
(2012)
Nature
, vol.486
, pp. 415-419
-
-
Nakamura, T.1
-
41
-
-
84897093768
-
Asymmetric reprogramming capacity of parental pronuclei in mouse zygotes
-
Liu, W., et al. Asymmetric reprogramming capacity of parental pronuclei in mouse zygotes. Cell Rep 6, 1008-1016 (2014
-
(2014)
Cell Rep
, vol.6
, pp. 1008-1016
-
-
Liu, W.1
-
42
-
-
33846309585
-
Comparison of histone modifications in in vivo and in vitro fertilization mouse embryos
-
Huang, J. C., et al. Comparison of histone modifications in in vivo and in vitro fertilization mouse embryos. Biochem Biophys Res Commun 354, 77-83 (2007
-
(2007)
Biochem Biophys Res Commun
, vol.354
, pp. 77-83
-
-
Huang, J.C.1
-
43
-
-
0027372662
-
Culture of preimplantation embryos
-
Lawitts, J. A., & Biggers, J. D. Culture of preimplantation embryos. Methods Enzymol 225, 153-164 (1993
-
(1993)
Methods Enzymol
, vol.225
, pp. 153-164
-
-
Lawitts, J.A.1
Biggers, J.D.2
-
44
-
-
4243155188
-
Intra-oocyte localization of MAD2 and its relationship with kinetochores, microtubules, and chromosomes in rat oocytes during meiosis
-
Zhang, D., et al. Intra-oocyte localization of MAD2 and its relationship with kinetochores, microtubules, and chromosomes in rat oocytes during meiosis. Biol Reprod 71, 740-748 (2004
-
(2004)
Biol Reprod
, vol.71
, pp. 740-748
-
-
Zhang, D.1
|