-
1
-
-
84890814629
-
Cancer immunotherapy
-
Couzin-Frankel J. Cancer immunotherapy. Science 2013, 342(6165):1432-1433.
-
(2013)
Science
, vol.342
, Issue.6165
, pp. 1432-1433
-
-
Couzin-Frankel, J.1
-
2
-
-
80051720194
-
Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
-
Porter D.L., et al. Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. NEJM 2011, 365(8):725-733.
-
(2011)
NEJM
, vol.365
, Issue.8
, pp. 725-733
-
-
Porter, D.L.1
-
3
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian S.L., et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. NEJM 2012, 366(26):2443-2454.
-
(2012)
NEJM
, vol.366
, Issue.26
, pp. 2443-2454
-
-
Topalian, S.L.1
-
4
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
Brahmer J.R., et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. NEJM 2012, 366(26):2455-2465.
-
(2012)
NEJM
, vol.366
, Issue.26
, pp. 2455-2465
-
-
Brahmer, J.R.1
-
5
-
-
84884535896
-
Cancer drug resistance: an evolving paradigm
-
Holohan C., et al. Cancer drug resistance: an evolving paradigm. Nat. Rev. Cancer 2013, 13(10):714-726.
-
(2013)
Nat. Rev. Cancer
, vol.13
, Issue.10
, pp. 714-726
-
-
Holohan, C.1
-
6
-
-
84921448324
-
The evolution of checkpoint blockade as a cancer therapy: what's here, what's next?
-
Shin D.S., Ribas A. The evolution of checkpoint blockade as a cancer therapy: what's here, what's next?. Curr. Opin. Immunol 2015, 33:23-35.
-
(2015)
Curr. Opin. Immunol
, vol.33
, pp. 23-35
-
-
Shin, D.S.1
Ribas, A.2
-
7
-
-
0029924107
-
Human tumor antigens recognized by T lymphocytes
-
Boon T., van der Bruggen P. Human tumor antigens recognized by T lymphocytes. J. Exp. Med 1996, 183(3):725-729.
-
(1996)
J. Exp. Med
, vol.183
, Issue.3
, pp. 725-729
-
-
Boon, T.1
van der Bruggen, P.2
-
8
-
-
0033103021
-
A new era for cancer immunotherapy based on the genes that encode cancer antigens
-
Rosenberg S.A. A new era for cancer immunotherapy based on the genes that encode cancer antigens. Immunity 1999, 10(3):281-287.
-
(1999)
Immunity
, vol.10
, Issue.3
, pp. 281-287
-
-
Rosenberg, S.A.1
-
9
-
-
0035399835
-
Immunity against solid tumors?
-
Zinkernagel R.M. Immunity against solid tumors?. Int. J. Cancer 2001, 93(1):1-5.
-
(2001)
Int. J. Cancer
, vol.93
, Issue.1
, pp. 1-5
-
-
Zinkernagel, R.M.1
-
10
-
-
0035902080
-
Progress in human tumour immunology and immunotherapy
-
Rosenberg S.A. Progress in human tumour immunology and immunotherapy. Nature 2001, 411(6835):380-384.
-
(2001)
Nature
, vol.411
, Issue.6835
, pp. 380-384
-
-
Rosenberg, S.A.1
-
11
-
-
33244472107
-
Tumor-infiltrating T lymphocytes: friends or foes?
-
Yu P., Fu Y.-X. Tumor-infiltrating T lymphocytes: friends or foes?. Lab. Invest 2006, 86(3):231-245.
-
(2006)
Lab. Invest
, vol.86
, Issue.3
, pp. 231-245
-
-
Yu, P.1
Fu, Y.-X.2
-
12
-
-
84925611946
-
Microenvironmental regulation of therapeutic response in cancer
-
Klemm F., Joyce J.A. Microenvironmental regulation of therapeutic response in cancer. Trends Cell Biol 2015, 25(4):198-213.
-
(2015)
Trends Cell Biol
, vol.25
, Issue.4
, pp. 198-213
-
-
Klemm, F.1
Joyce, J.A.2
-
13
-
-
84885757630
-
Immune modulation of the tumor microenvironment for enhancing cancer immunotherapy
-
Devaud C., et al. Immune modulation of the tumor microenvironment for enhancing cancer immunotherapy. Oncoimmunology 2013, 2(8):e25961.
-
(2013)
Oncoimmunology
, vol.2
, Issue.8
, pp. e25961
-
-
Devaud, C.1
-
14
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
Pardoll D.M. The blockade of immune checkpoints in cancer immunotherapy. Nat. Rev. Cancer 2012, 12(4):252-264.
-
(2012)
Nat. Rev. Cancer
, vol.12
, Issue.4
, pp. 252-264
-
-
Pardoll, D.M.1
-
15
-
-
0035846991
-
Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice
-
Nishimura H., et al. Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice. Science 2001, 291(5502):319-322.
-
(2001)
Science
, vol.291
, Issue.5502
, pp. 319-322
-
-
Nishimura, H.1
-
16
-
-
42649125225
-
PD-1 and its ligands in tolerance and immunity
-
Keir M.E., et al. PD-1 and its ligands in tolerance and immunity. Annu. Rev. Immunol 2008, 26:677-704.
-
(2008)
Annu. Rev. Immunol
, vol.26
, pp. 677-704
-
-
Keir, M.E.1
-
17
-
-
18544380239
-
Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion
-
Dong H., et al. Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat. Med 2002, 8(8):793-800.
-
(2002)
Nat. Med
, vol.8
, Issue.8
, pp. 793-800
-
-
Dong, H.1
-
18
-
-
0037126021
-
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
-
Iwai Y., et al. Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. PNAS 2002, 99(19):12293-12297.
-
(2002)
PNAS
, vol.99
, Issue.19
, pp. 12293-12297
-
-
Iwai, Y.1
-
19
-
-
84859158384
-
Targeting the PD-1/B7-H1 (PD-L1) pathway to activate anti-tumor immunity
-
Topalian S.L., Drake C.G., Pardoll D.M. Targeting the PD-1/B7-H1 (PD-L1) pathway to activate anti-tumor immunity. Curr. Opin. Immunol 2012, 24(2):207-212.
-
(2012)
Curr. Opin. Immunol
, vol.24
, Issue.2
, pp. 207-212
-
-
Topalian, S.L.1
Drake, C.G.2
Pardoll, D.M.3
-
20
-
-
0842325739
-
PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells
-
Blank C., et al. PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells. Cancer Res 2004, 64(3):1140-1145.
-
(2004)
Cancer Res
, vol.64
, Issue.3
, pp. 1140-1145
-
-
Blank, C.1
-
21
-
-
84877059916
-
T cell anergy, exhaustion, senescence, and stemness in the tumor microenvironment
-
Crespo J., et al. T cell anergy, exhaustion, senescence, and stemness in the tumor microenvironment. Curr. Opin. Immunol 2013, 25(2):214-221.
-
(2013)
Curr. Opin. Immunol
, vol.25
, Issue.2
, pp. 214-221
-
-
Crespo, J.1
-
22
-
-
84904024273
-
Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy
-
Taube J.M., et al. Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy. Clin. Cancer Res 2014, 20(19):5064-5074.
-
(2014)
Clin. Cancer Res
, vol.20
, Issue.19
, pp. 5064-5074
-
-
Taube, J.M.1
-
23
-
-
84920956735
-
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
-
Herbst R.S., et al. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature 2014, 515(7528):563-567.
-
(2014)
Nature
, vol.515
, Issue.7528
, pp. 563-567
-
-
Herbst, R.S.1
-
24
-
-
84933177430
-
Immune checkpoint combinations from mouse to man
-
Ai M., Curran M.A. Immune checkpoint combinations from mouse to man. Cancer Immunol. Immunother 2015, 64(7):885-892.
-
(2015)
Cancer Immunol. Immunother
, vol.64
, Issue.7
, pp. 885-892
-
-
Ai, M.1
Curran, M.A.2
-
25
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
Wolchok J.D., et al. Nivolumab plus ipilimumab in advanced melanoma. NEJM 2013, 369(2):122-133.
-
(2013)
NEJM
, vol.369
, Issue.2
, pp. 122-133
-
-
Wolchok, J.D.1
-
27
-
-
84929481482
-
Nivolumab and ipilimumab versus ipilimumab in untreated melanoma
-
Postow M.A., et al. Nivolumab and ipilimumab versus ipilimumab in untreated melanoma. NEJM 2015, 372(21):2006-2017.
-
(2015)
NEJM
, vol.372
, Issue.21
, pp. 2006-2017
-
-
Postow, M.A.1
-
28
-
-
84902825664
-
Improved survival with T cell clonotype stability after anti-CTLA-4 treatment in cancer patients
-
238ra70
-
Cha E., et al. Improved survival with T cell clonotype stability after anti-CTLA-4 treatment in cancer patients. Sci. Transl. Med 2014, 6(238):238ra70.
-
(2014)
Sci. Transl. Med
, vol.6
, Issue.238
-
-
Cha, E.1
-
29
-
-
84977161108
-
Mechanism of tumor rejection with doublets of CTLA-4, PD-1/PD-L1, or IDO blockade involves restored IL-2 production and proliferation of CD8 (+) T cells directly within the tumor microenvironment
-
Spranger S., et al. Mechanism of tumor rejection with doublets of CTLA-4, PD-1/PD-L1, or IDO blockade involves restored IL-2 production and proliferation of CD8 (+) T cells directly within the tumor microenvironment. J. Immunother. Cancer 2014, 2:3.
-
(2014)
J. Immunother. Cancer
, vol.2
, pp. 3
-
-
Spranger, S.1
-
30
-
-
33846465547
-
Immunostimulatory monoclonal antibodies for cancer therapy
-
Melero I., et al. Immunostimulatory monoclonal antibodies for cancer therapy. Nat. Rev. Cancer 2007, 7(2):95-106.
-
(2007)
Nat. Rev. Cancer
, vol.7
, Issue.2
, pp. 95-106
-
-
Melero, I.1
-
31
-
-
0026528181
-
Molecular and biological characterization of a murine ligand for CD40
-
Armitage R.J., et al. Molecular and biological characterization of a murine ligand for CD40. Nature 1992, 357(6373):80-82.
-
(1992)
Nature
, vol.357
, Issue.6373
, pp. 80-82
-
-
Armitage, R.J.1
-
32
-
-
33947223664
-
Prospect of targeting the CD40 pathway for cancer therapy
-
Vonderheide R.H. Prospect of targeting the CD40 pathway for cancer therapy. Clin. Cancer Res 2007, 13(4):1083-1088.
-
(2007)
Clin. Cancer Res
, vol.13
, Issue.4
, pp. 1083-1088
-
-
Vonderheide, R.H.1
-
33
-
-
0032482474
-
T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions
-
Schoenberger S.P., et al. T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature 1998, 393(6684):480-483.
-
(1998)
Nature
, vol.393
, Issue.6684
, pp. 480-483
-
-
Schoenberger, S.P.1
-
34
-
-
0032482356
-
Help for cytotoxic-T-cell responses is mediated by CD40 signalling
-
Bennett S.R., et al. Help for cytotoxic-T-cell responses is mediated by CD40 signalling. Nature 1998, 393(6684):478-480.
-
(1998)
Nature
, vol.393
, Issue.6684
, pp. 478-480
-
-
Bennett, S.R.1
-
36
-
-
0032896709
-
CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help
-
French R.R., et al. CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help. Nat. Med 1999, 5(5):548-553.
-
(1999)
Nat. Med
, vol.5
, Issue.5
, pp. 548-553
-
-
French, R.R.1
-
37
-
-
0032984496
-
CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy
-
Diehl L., et al. CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy. Nat. Med 1999, 5(7):774-779.
-
(1999)
Nat. Med
, vol.5
, Issue.7
, pp. 774-779
-
-
Diehl, L.1
-
38
-
-
0032984347
-
Conversion of tumor-specific CD4+ T-cell tolerance to T-cell priming through in vivo ligation of CD40
-
Sotomayor E.M., et al. Conversion of tumor-specific CD4+ T-cell tolerance to T-cell priming through in vivo ligation of CD40. Nat. Med 1999, 5(7):780-787.
-
(1999)
Nat. Med
, vol.5
, Issue.7
, pp. 780-787
-
-
Sotomayor, E.M.1
-
39
-
-
79953154967
-
CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans
-
Beatty G.L., et al. CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans. Science 2011, 331(6024):1612-1616.
-
(2011)
Science
, vol.331
, Issue.6024
, pp. 1612-1616
-
-
Beatty, G.L.1
-
40
-
-
84874845333
-
Agonistic CD40 antibodies and cancer therapy
-
Vonderheide R.H., Glennie M.J. Agonistic CD40 antibodies and cancer therapy. Clin. Cancer Res 2013, 19(5):1035-1043.
-
(2013)
Clin. Cancer Res
, vol.19
, Issue.5
, pp. 1035-1043
-
-
Vonderheide, R.H.1
Glennie, M.J.2
-
41
-
-
84885783438
-
Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy
-
Bouchlaka M.N., et al. Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy. J. Exp. Med 2013, 210(11):2223-2237.
-
(2013)
J. Exp. Med
, vol.210
, Issue.11
, pp. 2223-2237
-
-
Bouchlaka, M.N.1
-
42
-
-
84911904714
-
Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice
-
Mirsoian A., et al. Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice. J. Exp. Med 2014, 211(12):2373-2383.
-
(2014)
J. Exp. Med
, vol.211
, Issue.12
, pp. 2373-2383
-
-
Mirsoian, A.1
-
43
-
-
84911908525
-
Immunotherapy and the belly of the beast
-
Merghoub T., Wolchok J.D. Immunotherapy and the belly of the beast. J. Exp. Med 2014, 211(12):2327-2328.
-
(2014)
J. Exp. Med
, vol.211
, Issue.12
, pp. 2327-2328
-
-
Merghoub, T.1
Wolchok, J.D.2
-
44
-
-
84939572921
-
Engineering CAR-T cells: design concepts
-
Srivastava S., Riddell S.R. Engineering CAR-T cells: design concepts. Trends Immunol 2015, 36(8):494-502.
-
(2015)
Trends Immunol
, vol.36
, Issue.8
, pp. 494-502
-
-
Srivastava, S.1
Riddell, S.R.2
-
45
-
-
0036137615
-
Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRζ/CD28 receptor
-
Maher J., et al. Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRζ/CD28 receptor. Nat. Biotechnol 2002, 20(1):70-75.
-
(2002)
Nat. Biotechnol
, vol.20
, Issue.1
, pp. 70-75
-
-
Maher, J.1
-
46
-
-
84876325876
-
Chimeric antigen receptor-modified T cells for acute lymphoid leukemia
-
Grupp S.A., et al. Chimeric antigen receptor-modified T cells for acute lymphoid leukemia. NEJM 2013, 368(16):1509-1518.
-
(2013)
NEJM
, vol.368
, Issue.16
, pp. 1509-1518
-
-
Grupp, S.A.1
-
47
-
-
84896335556
-
Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia
-
224ra25
-
Davila M.L., et al. Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia. Sci. Transl. Med 2014, 6(224):224ra25.
-
(2014)
Sci. Transl. Med
, vol.6
, Issue.224
-
-
Davila, M.L.1
-
48
-
-
33750699642
-
A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer
-
Kershaw M.H., et al. A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer. Clin. Cancer Res 2006, 12(20):6106-6115.
-
(2006)
Clin. Cancer Res
, vol.12
, Issue.20
, pp. 6106-6115
-
-
Kershaw, M.H.1
-
49
-
-
55549145071
-
Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma
-
Pule M.A., et al. Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma. Nat. Med 2008, 14(11):1264-1270.
-
(2008)
Nat. Med
, vol.14
, Issue.11
, pp. 1264-1270
-
-
Pule, M.A.1
-
50
-
-
84908891854
-
Regional delivery of mesothelin-targeted CAR T cell therapy generates potent and long-lasting CD4-dependent tumor immunity
-
261ra151
-
Adusumilli P.S., et al. Regional delivery of mesothelin-targeted CAR T cell therapy generates potent and long-lasting CD4-dependent tumor immunity. Sci. Transl. Med 2014, 6(261):261ra151.
-
(2014)
Sci. Transl. Med
, vol.6
, Issue.261
-
-
Adusumilli, P.S.1
-
51
-
-
0032851160
-
Functions of cell surface heparan sulfate proteoglycans
-
Bernfield M., et al. Functions of cell surface heparan sulfate proteoglycans. Annu. Rev. Biochem 1999, 68(1):729-777.
-
(1999)
Annu. Rev. Biochem
, vol.68
, Issue.1
, pp. 729-777
-
-
Bernfield, M.1
-
52
-
-
84937758074
-
Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes
-
Caruana I., et al. Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes. Nat. Med 2015, 21(5):524-529.
-
(2015)
Nat. Med
, vol.21
, Issue.5
, pp. 524-529
-
-
Caruana, I.1
-
53
-
-
34447287858
-
Heparanase: structure, biological functions, and inhibition by heparin-derived mimetics of heparan sulfate
-
Vlodavsky I., et al. Heparanase: structure, biological functions, and inhibition by heparin-derived mimetics of heparan sulfate. Curr. Pharm. Des 2007, 13(20):2057-2073.
-
(2007)
Curr. Pharm. Des
, vol.13
, Issue.20
, pp. 2057-2073
-
-
Vlodavsky, I.1
-
54
-
-
84896902938
-
Chemokines and chemokine receptors: positioning cells for host defense and immunity
-
Griffith J.W., Sokol C.L., Luster A.D. Chemokines and chemokine receptors: positioning cells for host defense and immunity. Annu. Rev. Immunol 2014, 32:659-702.
-
(2014)
Annu. Rev. Immunol
, vol.32
, pp. 659-702
-
-
Griffith, J.W.1
Sokol, C.L.2
Luster, A.D.3
-
56
-
-
0142166426
-
Chemokines: agents for the immunotherapy of cancer?
-
Homey B., Müller A., Zlotnik A. Chemokines: agents for the immunotherapy of cancer?. Nat. Rev. Immunol 2002, 2(3):175-184.
-
(2002)
Nat. Rev. Immunol
, vol.2
, Issue.3
, pp. 175-184
-
-
Homey, B.1
Müller, A.2
Zlotnik, A.3
-
57
-
-
50049105173
-
Orchestrating the orchestrators: chemokines in control of T cell traffic
-
Bromley S.K., Mempel T.R., Luster A.D. Orchestrating the orchestrators: chemokines in control of T cell traffic. Nat. Immunol 2008, 9(9):970-980.
-
(2008)
Nat. Immunol
, vol.9
, Issue.9
, pp. 970-980
-
-
Bromley, S.K.1
Mempel, T.R.2
Luster, A.D.3
-
58
-
-
0346727325
-
Differential regulation of CCL21 in lymphoid/nonlymphoid tissues for effectively attracting T cells to peripheral tissues
-
Lo J.C., et al. Differential regulation of CCL21 in lymphoid/nonlymphoid tissues for effectively attracting T cells to peripheral tissues. J. Clin. Invest 2003, 112(10):1495-1505.
-
(2003)
J. Clin. Invest
, vol.112
, Issue.10
, pp. 1495-1505
-
-
Lo, J.C.1
-
59
-
-
0034192078
-
Secondary lymphoid tissue chemokine mediates T cell-dependent antitumor responses in vivo
-
Sharma S., et al. Secondary lymphoid tissue chemokine mediates T cell-dependent antitumor responses in vivo. J. Immunol 2000, 164(9):4558-4563.
-
(2000)
J. Immunol
, vol.164
, Issue.9
, pp. 4558-4563
-
-
Sharma, S.1
-
60
-
-
11144358381
-
Intratumoral administration of dendritic cells overexpressing CCL21 generates systemic antitumor responses and confers tumor immunity
-
Yang S.-C., et al. Intratumoral administration of dendritic cells overexpressing CCL21 generates systemic antitumor responses and confers tumor immunity. Clin. Cancer Res 2004, 10(8):2891-2901.
-
(2004)
Clin. Cancer Res
, vol.10
, Issue.8
, pp. 2891-2901
-
-
Yang, S.-C.1
-
61
-
-
77952231121
-
Induction of lymphoidlike stroma and immune escape by tumors that express the chemokine CCL21
-
Shields J.D., et al. Induction of lymphoidlike stroma and immune escape by tumors that express the chemokine CCL21. Science 2010, 328(5979):749-752.
-
(2010)
Science
, vol.328
, Issue.5979
, pp. 749-752
-
-
Shields, J.D.1
-
62
-
-
0030967209
-
Mig and IP-10: CXC chemokines that target lymphocytes
-
Farber J.M. Mig and IP-10: CXC chemokines that target lymphocytes. J. Leukoc. Biol 1997, 61(3):246-257.
-
(1997)
J. Leukoc. Biol
, vol.61
, Issue.3
, pp. 246-257
-
-
Farber, J.M.1
-
63
-
-
84937780190
-
Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy
-
da Silva R.B., et al. Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy. Nat. Immunol 2015, 16(8):850-858.
-
(2015)
Nat. Immunol
, vol.16
, Issue.8
, pp. 850-858
-
-
da Silva, R.B.1
-
64
-
-
84055199517
-
Cytokines in cancer immunotherapy
-
Lee S., Margolin K. Cytokines in cancer immunotherapy. Cancers 2011, 3(4):3856-3893.
-
(2011)
Cancers
, vol.3
, Issue.4
, pp. 3856-3893
-
-
Lee, S.1
Margolin, K.2
-
65
-
-
84891373820
-
License for destruction: tumor-specific cytokine targeting
-
Johansson A., Hamzah J., Ganss R. License for destruction: tumor-specific cytokine targeting. Trends Mol. Med 2014, 20(1):16-24.
-
(2014)
Trends Mol. Med
, vol.20
, Issue.1
, pp. 16-24
-
-
Johansson, A.1
Hamzah, J.2
Ganss, R.3
-
66
-
-
9644278053
-
Cytokines in cancer immunity and immunotherapy
-
Smyth M.J., et al. Cytokines in cancer immunity and immunotherapy. Immunol. Rev 2004, 202(1):275-293.
-
(2004)
Immunol. Rev
, vol.202
, Issue.1
, pp. 275-293
-
-
Smyth, M.J.1
-
67
-
-
77951019547
-
Targeted delivery of interferon-alpha via fusion to anti-CD20 results in potent antitumor activity against B-cell lymphoma
-
Xuan C., et al. Targeted delivery of interferon-alpha via fusion to anti-CD20 results in potent antitumor activity against B-cell lymphoma. Blood 2010, 115(14):2864-2871.
-
(2010)
Blood
, vol.115
, Issue.14
, pp. 2864-2871
-
-
Xuan, C.1
-
68
-
-
84892416698
-
Targeting the tumor microenvironment with interferon-β bridges innate and adaptive immune responses
-
Yang X., et al. Targeting the tumor microenvironment with interferon-β bridges innate and adaptive immune responses. Cancer Cell 2014, 25(1):37-48.
-
(2014)
Cancer Cell
, vol.25
, Issue.1
, pp. 37-48
-
-
Yang, X.1
-
69
-
-
84907495019
-
Therapeutic activity of high-dose intratumoral IFN-β requires direct effect on the tumor vasculature
-
Spaapen R.M., et al. Therapeutic activity of high-dose intratumoral IFN-β requires direct effect on the tumor vasculature. J. Immunol 2014, 193(8):4254-4260.
-
(2014)
J. Immunol
, vol.193
, Issue.8
, pp. 4254-4260
-
-
Spaapen, R.M.1
-
71
-
-
33749319703
-
Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
-
Galon J., et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 2006, 313(5795):1960-1964.
-
(2006)
Science
, vol.313
, Issue.5795
, pp. 1960-1964
-
-
Galon, J.1
-
72
-
-
79956329617
-
Tumor-infiltrating CD8+ lymphocytes predict clinical outcome in breast cancer
-
Mahmoud S.M., et al. Tumor-infiltrating CD8+ lymphocytes predict clinical outcome in breast cancer. J. Clin. Oncol 2011, 29(15):1949-1955.
-
(2011)
J. Clin. Oncol
, vol.29
, Issue.15
, pp. 1949-1955
-
-
Mahmoud, S.M.1
-
73
-
-
84856021596
-
Prognostic significance of tumor-infiltrating T cells in ovarian cancer: a meta-analysis
-
Hwang W.-T., et al. Prognostic significance of tumor-infiltrating T cells in ovarian cancer: a meta-analysis. Gynecol. Oncol 2012, 124(2):192-198.
-
(2012)
Gynecol. Oncol
, vol.124
, Issue.2
, pp. 192-198
-
-
Hwang, W.-T.1
-
74
-
-
65349113104
-
Immunoregulation by tumor necrosis factor superfamily member LIGHT
-
Wang Y., et al. Immunoregulation by tumor necrosis factor superfamily member LIGHT. Immunol. Rev 2009, 229(1):232-243.
-
(2009)
Immunol. Rev
, vol.229
, Issue.1
, pp. 232-243
-
-
Wang, Y.1
-
75
-
-
34548646455
-
Targeting the primary tumor to generate CTL for the effective eradication of spontaneous metastases
-
Yu P., et al. Targeting the primary tumor to generate CTL for the effective eradication of spontaneous metastases. J. Immunol 2007, 179(3):1960-1968.
-
(2007)
J. Immunol
, vol.179
, Issue.3
, pp. 1960-1968
-
-
Yu, P.1
-
76
-
-
10744227434
-
Priming of naive T cells inside tumors leads to eradication of established tumors
-
Yu P., et al. Priming of naive T cells inside tumors leads to eradication of established tumors. Nat. Immunol 2004, 5(2):141-149.
-
(2004)
Nat. Immunol
, vol.5
, Issue.2
, pp. 141-149
-
-
Yu, P.1
-
77
-
-
0033006011
-
Development and maturation of secondary lymphoid tissues
-
Fu Y.-X., Chaplin D.D. Development and maturation of secondary lymphoid tissues. Annu. Rev. Immunol 1999, 17(1):399-433.
-
(1999)
Annu. Rev. Immunol
, vol.17
, Issue.1
, pp. 399-433
-
-
Fu, Y.-X.1
Chaplin, D.D.2
-
78
-
-
17644400505
-
Network communications: lymphotoxins, LIGHT, and TNF
-
Ware C.F. Network communications: lymphotoxins, LIGHT, and TNF. Annu. Rev. Immunol 2005, 23:787-819.
-
(2005)
Annu. Rev. Immunol
, vol.23
, pp. 787-819
-
-
Ware, C.F.1
-
79
-
-
0032797272
-
Chemokines and cell migration in secondary lymphoid organs
-
Cyster J.G. Chemokines and cell migration in secondary lymphoid organs. Science 1999, 286(5447):2098-2102.
-
(1999)
Science
, vol.286
, Issue.5447
, pp. 2098-2102
-
-
Cyster, J.G.1
-
80
-
-
0347302952
-
Cytokines in cancer pathogenesis and cancer therapy
-
Dranoff G. Cytokines in cancer pathogenesis and cancer therapy. Nat. Rev. Cancer 2004, 4(1):11-22.
-
(2004)
Nat. Rev. Cancer
, vol.4
, Issue.1
, pp. 11-22
-
-
Dranoff, G.1
-
81
-
-
84880923978
-
Newly described pattern recognition receptors team up against intracellular pathogens
-
Broz P., Monack D.M. Newly described pattern recognition receptors team up against intracellular pathogens. Nat. Rev. Immunol 2013, 13(8):551-565.
-
(2013)
Nat. Rev. Immunol
, vol.13
, Issue.8
, pp. 551-565
-
-
Broz, P.1
Monack, D.M.2
-
82
-
-
17144404177
-
IRF-7 is the master regulator of type-I interferon-dependent immune responses
-
Honda K., et al. IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature 2005, 434(7034):772-777.
-
(2005)
Nature
, vol.434
, Issue.7034
, pp. 772-777
-
-
Honda, K.1
-
84
-
-
84859489110
-
CpG still rocks! Update on an accidental drug
-
Krieg A.M. CpG still rocks! Update on an accidental drug. Nucleic Acid Ther 2012, 22(2):77-89.
-
(2012)
Nucleic Acid Ther
, vol.22
, Issue.2
, pp. 77-89
-
-
Krieg, A.M.1
-
85
-
-
54749114415
-
Systemic targeting of CpG-ODN to the tumor microenvironment with anti-neu-CpG hybrid molecule and T regulatory cell depletion induces memory responses in BALB-neuT tolerant mice
-
Sharma S., et al. Systemic targeting of CpG-ODN to the tumor microenvironment with anti-neu-CpG hybrid molecule and T regulatory cell depletion induces memory responses in BALB-neuT tolerant mice. Cancer Res 2008, 68(18):7530-7540.
-
(2008)
Cancer Res
, vol.68
, Issue.18
, pp. 7530-7540
-
-
Sharma, S.1
-
86
-
-
84871005809
-
Intratumoral delivery of CpG-conjugated anti-MUC1 antibody enhances NK cell anti-tumor activity
-
Schettini J., et al. Intratumoral delivery of CpG-conjugated anti-MUC1 antibody enhances NK cell anti-tumor activity. Cancer Immunol. Immunother 2012, 61(11):2055-2065.
-
(2012)
Cancer Immunol. Immunother
, vol.61
, Issue.11
, pp. 2055-2065
-
-
Schettini, J.1
-
87
-
-
40949133887
-
CpG oligodeoxynucleotides as immunotherapy in cancer
-
Jahrsdörfer B., Weiner G.J. CpG oligodeoxynucleotides as immunotherapy in cancer. Update Cancer Ther 2008, 3(1):27-32.
-
(2008)
Update Cancer Ther
, vol.3
, Issue.1
, pp. 27-32
-
-
Jahrsdörfer, B.1
Weiner, G.J.2
-
88
-
-
84912120595
-
STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors
-
Woo S.-R., et al. STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors. Immunity 2014, 41(5):830-842.
-
(2014)
Immunity
, vol.41
, Issue.5
, pp. 830-842
-
-
Woo, S.-R.1
-
89
-
-
84912128872
-
STING-dependent cytosolic DNA sensing promotes radiation-induced type I interferon-dependent antitumor immunity in immunogenic tumors
-
Deng L., et al. STING-dependent cytosolic DNA sensing promotes radiation-induced type I interferon-dependent antitumor immunity in immunogenic tumors. Immunity 2014, 41(5):843-852.
-
(2014)
Immunity
, vol.41
, Issue.5
, pp. 843-852
-
-
Deng, L.1
|