-
1
-
-
5244326376
-
Über den jetzigen Stand der Chemotherapie
-
COI: 1:CAS:528:DyaD1MXlsFWr
-
Ehrlich P (1909) Über den jetzigen Stand der Chemotherapie. Ber Dtsch Chem Ges 42:17–47
-
(1909)
Ber Dtsch Chem Ges
, vol.42
, pp. 17-47
-
-
Ehrlich, P.1
-
2
-
-
0016318314
-
Immunological surveillance against altered self components by sensitised T lymphocytes in lymphocytic choriomeningitis
-
COI: 1:STN:280:DyaE2M%2FivFelsQ%3D%3D, PID: 4547543
-
Zinkernagel RM, Doherty PC (1974) Immunological surveillance against altered self components by sensitised T lymphocytes in lymphocytic choriomeningitis. Nature 251:547–548
-
(1974)
Nature
, vol.251
, pp. 547-548
-
-
Zinkernagel, R.M.1
Doherty, P.C.2
-
3
-
-
4644324025
-
Cancer immunotherapy: moving beyond current vaccines
-
COI: 1:CAS:528:DC%2BD2cXntFSktL0%3D, PID: 15340416
-
Rosenberg SA, Yang JC, Restifo NP (2004) Cancer immunotherapy: moving beyond current vaccines. Nat Med 10:909–915
-
(2004)
Nat Med
, vol.10
, pp. 909-915
-
-
Rosenberg, S.A.1
Yang, J.C.2
Restifo, N.P.3
-
4
-
-
0030807565
-
Antigenic cancer cells grow progressively in immune hosts without evidence for T cell exhaustion or systemic anergy
-
COI: 1:CAS:528:DyaK2sXkvVaksLg%3D, PID: 9221752
-
Wick M, Dubey P, Koeppen H, Siegel CT, Fields PE, Chen L, Bluestone JA, Schreiber H (1997) Antigenic cancer cells grow progressively in immune hosts without evidence for T cell exhaustion or systemic anergy. J Exp Med 186:229–238
-
(1997)
J Exp Med
, vol.186
, pp. 229-238
-
-
Wick, M.1
Dubey, P.2
Koeppen, H.3
Siegel, C.T.4
Fields, P.E.5
Chen, L.6
Bluestone, J.A.7
Schreiber, H.8
-
5
-
-
0029120245
-
CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
-
COI: 1:CAS:528:DyaK2MXntFKhsL4%3D, PID: 7543139
-
Krummel MF, Allison JP (1995) CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J Exp Med 182:459–465
-
(1995)
J Exp Med
, vol.182
, pp. 459-465
-
-
Krummel, M.F.1
Allison, J.P.2
-
6
-
-
0029947568
-
Enhancement of antitumor immunity by CTLA-4 blockade
-
COI: 1:CAS:528:DyaK28XhvVWmsLk%3D, PID: 8596936
-
Leach DR, Krummel MF, Allison JP (1996) Enhancement of antitumor immunity by CTLA-4 blockade. Science 271:1734–1736
-
(1996)
Science
, vol.271
, pp. 1734-1736
-
-
Leach, D.R.1
Krummel, M.F.2
Allison, J.P.3
-
7
-
-
0026700235
-
Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death
-
COI: 1:CAS:528:DyaK3sXkslShtbs%3D, PID: 1396582
-
Ishida Y, Agata Y, Shibahara K, Honjo T (1992) Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. EMBO J 11:3887–3895
-
(1992)
EMBO J
, vol.11
, pp. 3887-3895
-
-
Ishida, Y.1
Agata, Y.2
Shibahara, K.3
Honjo, T.4
-
8
-
-
0031007143
-
Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors
-
COI: 1:CAS:528:DyaK2sXjsFOhtr8%3D, PID: 9176498
-
Melero I, Shuford WW, Newby SA, Aruffo A, Ledbetter JA, Hellstrom KE, Mittler RS, Chen L (1997) Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors. Nat Med 3:682–685
-
(1997)
Nat Med
, vol.3
, pp. 682-685
-
-
Melero, I.1
Shuford, W.W.2
Newby, S.A.3
Aruffo, A.4
Ledbetter, J.A.5
Hellstrom, K.E.6
Mittler, R.S.7
Chen, L.8
-
9
-
-
0034651736
-
Engagement of the OX-40 receptor in vivo enhances antitumor immunity
-
COI: 1:CAS:528:DC%2BD3cXhtlymu7g%3D, PID: 10657670
-
Weinberg AD, Rivera MM, Prell R et al (2000) Engagement of the OX-40 receptor in vivo enhances antitumor immunity. J Immunol 164:2160–2169
-
(2000)
J Immunol
, vol.164
, pp. 2160-2169
-
-
Weinberg, A.D.1
Rivera, M.M.2
Prell, R.3
-
10
-
-
84877059530
-
The TNFRs OX40, 4-1BB, and CD40 as targets for cancer immunotherapy
-
COI: 1:CAS:528:DC%2BC3sXisVyitb4%3D, PID: 23414607
-
Moran AE, Kovacsovics-Bankowski M, Weinberg AD (2013) The TNFRs OX40, 4-1BB, and CD40 as targets for cancer immunotherapy. Curr Opin Immunol 25:230–237
-
(2013)
Curr Opin Immunol
, vol.25
, pp. 230-237
-
-
Moran, A.E.1
Kovacsovics-Bankowski, M.2
Weinberg, A.D.3
-
11
-
-
84873411673
-
Clinical targeting of the TNF and TNFR superfamilies
-
COI: 1:CAS:528:DC%2BC3sXhtFSgtrk%3D, PID: 23334208
-
Croft M, Benedict CA, Ware CF (2013) Clinical targeting of the TNF and TNFR superfamilies. Nat Rev Drug Discov 12:147–168
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 147-168
-
-
Croft, M.1
Benedict, C.A.2
Ware, C.F.3
-
12
-
-
84873396202
-
Targeting the B7 family of co-stimulatory molecules: successes and challenges
-
COI: 1:CAS:528:DC%2BC3sXhsl2nsbbM, PID: 23329394
-
Podojil JR, Miller SD (2013) Targeting the B7 family of co-stimulatory molecules: successes and challenges. BioDrugs 27:1–13
-
(2013)
BioDrugs
, vol.27
-
-
Podojil, J.R.1
Miller, S.D.2
-
13
-
-
0033590502
-
ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28
-
COI: 1:CAS:528:DyaK1MXpvVGnug%3D%3D, PID: 9930702
-
Hutloff A, Dittrich AM, Beier KC, Eljaschewitsch B, Kraft R, Anagnostopoulos I, Kroczek RA (1999) ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28. Nature 397:263–266
-
(1999)
Nature
, vol.397
, pp. 263-266
-
-
Hutloff, A.1
Dittrich, A.M.2
Beier, K.C.3
Eljaschewitsch, B.4
Kraft, R.5
Anagnostopoulos, I.6
Kroczek, R.A.7
-
14
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
-
COI: 1:CAS:528:DyaK2MXptlOlurk%3D, PID: 7481803
-
Waterhouse P, Penninger JM, Timms E, Wakeham A, Shahinian A, Lee KP, Thompson CB, Griesser H, Mak TW (1995) Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science 270:985–988
-
(1995)
Science
, vol.270
, pp. 985-988
-
-
Waterhouse, P.1
Penninger, J.M.2
Timms, E.3
Wakeham, A.4
Shahinian, A.5
Lee, K.P.6
Thompson, C.B.7
Griesser, H.8
Mak, T.W.9
-
15
-
-
0033180181
-
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
-
COI: 1:CAS:528:DyaK1MXlvVShsb8%3D, PID: 10485649
-
Nishimura H, Nose M, Hiai H, Minato N, Honjo T (1999) Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity 11:141–151
-
(1999)
Immunity
, vol.11
, pp. 141-151
-
-
Nishimura, H.1
Nose, M.2
Hiai, H.3
Minato, N.4
Honjo, T.5
-
16
-
-
0035846991
-
Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice
-
COI: 1:CAS:528:DC%2BD3MXktlKlsw%3D%3D, PID: 11209085
-
Nishimura H, Okazaki T, Tanaka Y et al (2001) Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice. Science 291:319–322
-
(2001)
Science
, vol.291
, pp. 319-322
-
-
Nishimura, H.1
Okazaki, T.2
Tanaka, Y.3
-
17
-
-
77749279776
-
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
-
COI: 1:CAS:528:DC%2BC3cXjtlKms7c%3D, PID: 20160101
-
Curran MA, Montalvo W, Yagita H, Allison JP (2010) PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors. Proc Natl Acad Sci U S A 107:4275–4280
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 4275-4280
-
-
Curran, M.A.1
Montalvo, W.2
Yagita, H.3
Allison, J.P.4
-
18
-
-
34447646310
-
Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses
-
COI: 1:CAS:528:DC%2BD2sXosFeqtrk%3D, PID: 17629517
-
Butte MJ, Keir ME, Phamduy TB, Sharpe AH, Freeman GJ (2007) Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses. Immunity 27:111–122
-
(2007)
Immunity
, vol.27
, pp. 111-122
-
-
Butte, M.J.1
Keir, M.E.2
Phamduy, T.B.3
Sharpe, A.H.4
Freeman, G.J.5
-
19
-
-
84874889330
-
Clinical development of immunostimulatory monoclonal antibodies and opportunities for combination
-
COI: 1:CAS:528:DC%2BC3sXjsFektbs%3D, PID: 23460531
-
Melero I, Grimaldi AM, Perez-Gracia JL, Ascierto PA (2013) Clinical development of immunostimulatory monoclonal antibodies and opportunities for combination. Clin Cancer Res 19:997–1008
-
(2013)
Clin Cancer Res
, vol.19
, pp. 997-1008
-
-
Melero, I.1
Grimaldi, A.M.2
Perez-Gracia, J.L.3
Ascierto, P.A.4
-
20
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
COI: 1:CAS:528:DC%2BC3sXht1ektbrF, PID: 23724867
-
Wolchok JD, Kluger H, Callahan MK et al (2013) Nivolumab plus ipilimumab in advanced melanoma. New Engl J Med 369:122–133
-
(2013)
New Engl J Med
, vol.369
, pp. 122-133
-
-
Wolchok, J.D.1
Kluger, H.2
Callahan, M.K.3
-
21
-
-
84907498833
-
Survival, response duration, and activity by BRAF mutation (MT) status of nivolumab (NIVO, anti-PD-1, BMS-936558, ONO-4538) and ipilimumab (IPI) concurrent therapy in advanced melanoma (MEL)
-
Sznol M, Kluger HM, Callahan MK et al (2014) Survival, response duration, and activity by BRAF mutation (MT) status of nivolumab (NIVO, anti-PD-1, BMS-936558, ONO-4538) and ipilimumab (IPI) concurrent therapy in advanced melanoma (MEL). J Clin Oncol 32(5s Suppl):LBA9003
-
(2014)
J Clin Oncol
, vol.32
, pp. LBA9003
-
-
Sznol, M.1
Kluger, H.M.2
Callahan, M.K.3
-
22
-
-
84879104519
-
Dual blockade of PD-1 and CTLA-4 combined with tumor vaccine effectively restores T-cell rejection function in tumors
-
COI: 1:CAS:528:DC%2BC3sXpsVens78%3D, PID: 23633484
-
Duraiswamy J, Kaluza KM, Freeman GJ, Coukos G (2013) Dual blockade of PD-1 and CTLA-4 combined with tumor vaccine effectively restores T-cell rejection function in tumors. Cancer Res 73:3591–3603
-
(2013)
Cancer Res
, vol.73
, pp. 3591-3603
-
-
Duraiswamy, J.1
Kaluza, K.M.2
Freeman, G.J.3
Coukos, G.4
-
23
-
-
84884901819
-
Peripheral and tumor immune correlates in patients with advanced melanoma treated with combination nivolumab (anti-PD-1, BMS-936558, ONO-4538) and ipilimumab
-
Callahan MK, Horak CE, Curran MA et al (2013) Peripheral and tumor immune correlates in patients with advanced melanoma treated with combination nivolumab (anti-PD-1, BMS-936558, ONO-4538) and ipilimumab. J Clin Oncol 31(Suppl):3003
-
(2013)
J Clin Oncol
, vol.31
, pp. 3003
-
-
Callahan, M.K.1
Horak, C.E.2
Curran, M.A.3
-
24
-
-
84863672266
-
Biomarkers on melanoma patient T cells associated with ipilimumab treatment
-
COI: 1:CAS:528:DC%2BC3sXitVynsL0%3D, PID: 22788688
-
Wang W, Yu D, Sarnaik AA, Yu B, Hall M, Morelli D, Zhang Y, Zhao X, Weber JS (2012) Biomarkers on melanoma patient T cells associated with ipilimumab treatment. J Transl Med 10:146
-
(2012)
J Transl Med
, vol.10
, pp. 146
-
-
Wang, W.1
Yu, D.2
Sarnaik, A.A.3
Yu, B.4
Hall, M.5
Morelli, D.6
Zhang, Y.7
Zhao, X.8
Weber, J.S.9
-
25
-
-
85003055100
-
Increased frequency of ICOS+ CD4 T cells as a pharmacodynamic biomarker for anti-CTLA-4 therapy
-
PID: 24777852
-
Ng Tang D, Shen Y, Sun J, Wen S, Wolchok JD, Yuan J, Allison JP, Sharma P (2013) Increased frequency of ICOS+ CD4 T cells as a pharmacodynamic biomarker for anti-CTLA-4 therapy. Cancer Immunol Res 1:229–234
-
(2013)
Cancer Immunol Res
, vol.1
, pp. 229-234
-
-
Ng Tang, D.1
Shen, Y.2
Sun, J.3
Wen, S.4
Wolchok, J.D.5
Yuan, J.6
Allison, J.P.7
Sharma, P.8
-
26
-
-
77952337834
-
Preoperative CTLA-4 blockade: tolerability and immune monitoring in the setting of a presurgical clinical trial
-
COI: 1:CAS:528:DC%2BC3cXlvF2hsrY%3D, PID: 20460488
-
Carthon BC, Wolchok JD, Yuan J et al (2010) Preoperative CTLA-4 blockade: tolerability and immune monitoring in the setting of a presurgical clinical trial. Clin Cancer Res 16:2861–2871
-
(2010)
Clin Cancer Res
, vol.16
, pp. 2861-2871
-
-
Carthon, B.C.1
Wolchok, J.D.2
Yuan, J.3
-
27
-
-
80051694786
-
The ICOS/ICOSL pathway is required for optimal antitumor responses mediated by anti-CTLA-4 therapy
-
COI: 1:CAS:528:DC%2BC3MXhtVSrtb3P, PID: 21708958
-
Fu T, He Q, Sharma P (2011) The ICOS/ICOSL pathway is required for optimal antitumor responses mediated by anti-CTLA-4 therapy. Cancer Res 71:5445–5454
-
(2011)
Cancer Res
, vol.71
, pp. 5445-5454
-
-
Fu, T.1
He, Q.2
Sharma, P.3
-
28
-
-
84897940775
-
Engagement of the ICOS pathway markedly enhances efficacy of CTLA-4 blockade in cancer immunotherapy
-
COI: 1:CAS:528:DC%2BC2cXmtVOit7s%3D, PID: 24687957
-
Fan X, Quezada SA, Sepulveda MA, Sharma P, Allison JP (2014) Engagement of the ICOS pathway markedly enhances efficacy of CTLA-4 blockade in cancer immunotherapy. J Exp Med 211:715–725
-
(2014)
J Exp Med
, vol.211
, pp. 715-725
-
-
Fan, X.1
Quezada, S.A.2
Sepulveda, M.A.3
Sharma, P.4
Allison, J.P.5
-
29
-
-
77953715389
-
4-1BB as a therapeutic target for human disease
-
COI: 1:CAS:528:DC%2BC3MXhtF2itLvK, PID: 19760070
-
Lee SW, Croft M (2009) 4-1BB as a therapeutic target for human disease. Adv Exp Med Biol 647:120–129
-
(2009)
Adv Exp Med Biol
, vol.647
, pp. 120-129
-
-
Lee, S.W.1
Croft, M.2
-
30
-
-
65349153714
-
Immune regulation by 4-1BB and 4-1BBL: complexities and challenges
-
COI: 1:CAS:528:DC%2BD1MXhsFGls7nO, PID: 19426223
-
Wang C, Lin GH, McPherson AJ, Watts TH (2009) Immune regulation by 4-1BB and 4-1BBL: complexities and challenges. Immunol Rev 229:192–215
-
(2009)
Immunol Rev
, vol.229
, pp. 192-215
-
-
Wang, C.1
Lin, G.H.2
McPherson, A.J.3
Watts, T.H.4
-
31
-
-
34548512807
-
Established B16 tumors are rejected following treatment with GM-CSF-secreting tumor cell immunotherapy in combination with anti-4-1BB mAb
-
COI: 1:CAS:528:DC%2BD2sXhtVCnsrbJ, PID: 17706463
-
Li B, Lin J, Vanroey M, Jure-Kunkel M, Jooss K (2007) Established B16 tumors are rejected following treatment with GM-CSF-secreting tumor cell immunotherapy in combination with anti-4-1BB mAb. Clin Immunol 125:76–87
-
(2007)
Clin Immunol
, vol.125
, pp. 76-87
-
-
Li, B.1
Lin, J.2
Vanroey, M.3
Jure-Kunkel, M.4
Jooss, K.5
-
32
-
-
84878648242
-
Systemic 4-1BB activation induces a novel T cell phenotype driven by high expression of Eomesodermin
-
COI: 1:CAS:528:DC%2BC3sXmtVWqsLg%3D, PID: 23547098
-
Curran MA, Geiger TL, Montalvo W, Kim M, Reiner SL, Al-Shamkhani A, Sun JC, Allison JP (2013) Systemic 4-1BB activation induces a novel T cell phenotype driven by high expression of Eomesodermin. J Exp Med 210:743–755
-
(2013)
J Exp Med
, vol.210
, pp. 743-755
-
-
Curran, M.A.1
Geiger, T.L.2
Montalvo, W.3
Kim, M.4
Reiner, S.L.5
Al-Shamkhani, A.6
Sun, J.C.7
Allison, J.P.8
-
33
-
-
84904207094
-
Focal radiation therapy combined with 4-1BB activation and CTLA-4 blockade yields long-term survival and a protective antigen-specific memory response in a murine glioma model
-
PID: 25013914
-
Belcaid Z, Phallen JA, Zeng J et al (2014) Focal radiation therapy combined with 4-1BB activation and CTLA-4 blockade yields long-term survival and a protective antigen-specific memory response in a murine glioma model. PLoS One 9:e101764
-
(2014)
PLoS One
, vol.9
, pp. e101764
-
-
Belcaid, Z.1
Phallen, J.A.2
Zeng, J.3
-
34
-
-
79955785050
-
Combination CTLA-4 blockade and 4-1BB activation enhances tumor rejection by increasing T-cell infiltration, proliferation, and cytokine production
-
COI: 1:CAS:528:DC%2BC3MXlsl2gtLc%3D, PID: 21559358
-
Curran MA, Kim M, Montalvo W, Al-Shamkhani A, Allison JP (2011) Combination CTLA-4 blockade and 4-1BB activation enhances tumor rejection by increasing T-cell infiltration, proliferation, and cytokine production. PLoS One 6:e19499
-
(2011)
PLoS One
, vol.6
, pp. e19499
-
-
Curran, M.A.1
Kim, M.2
Montalvo, W.3
Al-Shamkhani, A.4
Allison, J.P.5
-
35
-
-
33746924449
-
Combination therapy with anti-CTL antigen-4 and anti-4-1BB antibodies enhances cancer immunity and reduces autoimmunity
-
COI: 1:CAS:528:DC%2BD28XmvFGktbk%3D, PID: 16849577
-
Kocak E, Lute K, Chang X et al (2006) Combination therapy with anti-CTL antigen-4 and anti-4-1BB antibodies enhances cancer immunity and reduces autoimmunity. Cancer Res 66:7276–7284
-
(2006)
Cancer Res
, vol.66
, pp. 7276-7284
-
-
Kocak, E.1
Lute, K.2
Chang, X.3
-
36
-
-
0036467421
-
Administration of agonistic anti-4-1BB monoclonal antibody leads to the amelioration of experimental autoimmune encephalomyelitis
-
COI: 1:CAS:528:DC%2BD38XpsFerug%3D%3D, PID: 11801689
-
Sun Y, Lin X, Chen HM, Wu Q, Subudhi SK, Chen L, Fu YX (2002) Administration of agonistic anti-4-1BB monoclonal antibody leads to the amelioration of experimental autoimmune encephalomyelitis. J Immunol 168:1457–1465
-
(2002)
J Immunol
, vol.168
, pp. 1457-1465
-
-
Sun, Y.1
Lin, X.2
Chen, H.M.3
Wu, Q.4
Subudhi, S.K.5
Chen, L.6
Fu, Y.X.7
-
37
-
-
80051626171
-
4-1BB triggering ameliorates experimental autoimmune encephalomyelitis by modulating the balance between Th17 and regulatory T cells
-
COI: 1:CAS:528:DC%2BC3MXptVamsbs%3D, PID: 21715692
-
Kim YH, Choi BK, Shin SM et al (2011) 4-1BB triggering ameliorates experimental autoimmune encephalomyelitis by modulating the balance between Th17 and regulatory T cells. J Immunol 187:1120–1128
-
(2011)
J Immunol
, vol.187
, pp. 1120-1128
-
-
Kim, Y.H.1
Choi, B.K.2
Shin, S.M.3
-
38
-
-
84856769074
-
Evaluation of serum IL-17 levels during ipilimumab therapy: correlation with colitis
-
Callahan MK, Yang A, Tandon S et al (2011) Evaluation of serum IL-17 levels during ipilimumab therapy: correlation with colitis. J Clin Oncol 29(Suppl):2505
-
(2011)
J Clin Oncol
, vol.29
, pp. 2505
-
-
Callahan, M.K.1
Yang, A.2
Tandon, S.3
-
39
-
-
84904251418
-
Humanized mice as a model for aberrant responses in human T cell immunotherapy
-
COI: 1:CAS:528:DC%2BC2cXhtFSmtrnK, PID: 24943216
-
Vudattu NK, Waldron-Lynch F, Truman LA, Deng S, Preston-Hurlburt P, Torres R, Raycroft MT, Mamula MJ, Herold KC (2014) Humanized mice as a model for aberrant responses in human T cell immunotherapy. J Immunol 193:587–596
-
(2014)
J Immunol
, vol.193
, pp. 587-596
-
-
Vudattu, N.K.1
Waldron-Lynch, F.2
Truman, L.A.3
Deng, S.4
Preston-Hurlburt, P.5
Torres, R.6
Raycroft, M.T.7
Mamula, M.J.8
Herold, K.C.9
-
40
-
-
78449237499
-
Clinical experiences with anti-CD137 and anti-PD1 therapeutic antibodies
-
COI: 1:CAS:528:DC%2BC3cXhsVWrur7P, PID: 21074066
-
Ascierto PA, Simeone E, Sznol M, Fu YX, Melero I (2010) Clinical experiences with anti-CD137 and anti-PD1 therapeutic antibodies. Semin Oncol 37:508–516
-
(2010)
Semin Oncol
, vol.37
, pp. 508-516
-
-
Ascierto, P.A.1
Simeone, E.2
Sznol, M.3
Fu, Y.X.4
Melero, I.5
-
41
-
-
84907284200
-
Anti-CTLA-4 therapy broadens the melanoma-reactive CD8+ T cell response
-
PID: 25232180
-
Kvistborg P, Philips D, Kelderman S et al (2014) Anti-CTLA-4 therapy broadens the melanoma-reactive CD8+ T cell response. Sci Transl Med 6:254ra128
-
(2014)
Sci Transl Med
, vol.6
, pp. 254ra128
-
-
Kvistborg, P.1
Philips, D.2
Kelderman, S.3
-
42
-
-
84929318014
-
Melanoma-intrinsic β-catenin signaling prevents T cell infiltration and anti-tumor immunity
-
Spranger S, Bao R, Gajewski TF (2014) Melanoma-intrinsic β-catenin signaling prevents T cell infiltration and anti-tumor immunity. J ImmunoTherapy Cancer 2(Suppl 3):O15
-
(2014)
J ImmunoTherapy Cancer
, vol.2
, pp. O15
-
-
Spranger, S.1
Bao, R.2
Gajewski, T.F.3
-
43
-
-
84920921528
-
Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
-
COI: 1:CAS:528:DC%2BC2cXitFamsr7N, PID: 25428507
-
Gubin MM, Zhang X, Schuster H et al (2014) Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens. Nature 515:577–581
-
(2014)
Nature
, vol.515
, pp. 577-581
-
-
Gubin, M.M.1
Zhang, X.2
Schuster, H.3
-
44
-
-
84872841412
-
Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma
-
PID: 24043743
-
van Rooij N, van Buuren MM, Philips D et al (2013) Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma. J Clin Oncol 31:e439–e442
-
(2013)
J Clin Oncol
, vol.31
, pp. e439-e442
-
-
van Rooij, N.1
van Buuren, M.M.2
Philips, D.3
|